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Coliprotec F18 (Canada)

This page contains information on Coliprotec F18 for veterinary use.
The information provided typically includes the following:
  • Coliprotec F18 Indications
  • Warnings and cautions for Coliprotec F18
  • Direction and dosage information for Coliprotec F18

Coliprotec F18

This treatment applies to the following species:
Manufacturer: Prevtec microbia

Escherichia coli Vaccine, Avirulent Live Culture, Porcine Isolate

Frozen form

FOR ORAL USE ONLY IN SWINE

Distribution under conditional license in Canada

Description Of The Vaccine

The oral live vaccine Coliprotec®F18 containing naturally avirulent Escherichia coli (E. coli) is being used in healthy pigs, 18 days of age or older, as an aid in the control of Post-Weaning Diarrhea and Edema Disease caused by F18-positive pathogenic E. coli. The vaccine is conditionally licensed in Canada, pending additional data demonstrating product efficacy against Edema Disease.

Precautions

- Keep frozen until use at -70 to -80°C (-158 to -176°F)

- For oral use only

- Materials and water used for the preparation and administration of the vaccine must be free of antibiotic or disinfectant residue to prevent inactivation of Coliprotec®F18 vaccine

- Do not administer antibiotics or other live vaccines for a minimum of 3 days prior to and after vaccination

- Withdraw antibiotics and disinfectants from drinking water for a minimum of 3 days prior to and after vaccination

- Use entire content when first opened

- Diluted vaccine should be used within 4 hours

- Do not vaccinate within 21 days before slaughter

Warning

Anaphylactic reactions may occur. Use epinephrine as antidote. Dispose unused product and empty containers according to local waste disposal requirements.

Coliprotec F18 Dosage And Administration

The Coliprotec®F18 vaccine is administered orally using one dose per pig. Three methods of administration are recommended, being: 1) Individual oral administration using a syringe or a drencher, 2) Conventional drinking water systems and 3) Automatic medicator (proportioner) watering system.

Directions For Administration

Thaw the vaccine vial immediately prior vaccination at 2-8°C or in a cool water bath until complete thawing.

Individual administration using a syringe

Transfer the vaccine to a graduated sterile container. Rinse the bottle with 10 mL of water and transfer to the same container. DILUTE THE VACCINE IN THE CONTAINER USING WATER TO OBTAIN A FINAL VOLUME OF 3 ML PER DOSE. Using a syringe or a drencher, administer a 3-mL oral single dose of the vaccine preparation per pig.

Conventional drinking water system

Withhold water for 1 to 2 hours immediately before vaccination. Flush the watering system with untreated water. Ensure that pigs can drink in 4 hours by providing watering space so that all the pigs can drink easily.

On the day prior to vaccination, determine the volume (mL) of water consumed within 4 hours, by the number of pigs to be treated. If the information is not available, please refer to the reference table below. Transfer the vaccine to a sterile container. Rinse the vial with 10 mL of water and transfer to the same container. Dilute the vaccine with the determined volume of water. Add the bacterial suspension to the drinking water tanks for the appropriate number of pigs. The diluted culture should be consumed within 4 hours.

Automatic medicator watering system

Withhold water for 1 to 2 hours immediately before vaccination. Flush the watering system with untreated water. Ensure that pigs can drink in 4 hours by providing watering space so that all the pigs can drink easily.

Determine the volume of stock solution to be prepared for the number of pigs to treat: On the day prior to vaccination, pre-fill the proportioner container with a known volume of water and determine the volume (mL) consumed within 4 hours by the number of pigs to be treated. If the information is not available, please refer to the reference table below. Select the volume of the proportioner for 30 mL of stock solution per 4 litres of water (1 oz per gallon). Many proportioners are factory set at 1:128 to deliver 1 oz per gallon of water.

Prepare the stock solution of culture: Use the number of doses equal to the number of pigs to be treated. Transfer the vaccine in the proportioner container. Rinse the vial with 10 mL of water and transfer to the same container. Add the appropriate volume of water to reach the determined volume of stock solution. Mix well. Insert the tube of the proportioner into the stock solution (vaccine preparation) and open the water system. The diluted culture should be consumed within 4 hours.

In case of concerns about the presence of disinfectant residues in the drinking water, it is recommended to add skimmed milk powder as a stabilizer into the drinking water prior to adding the vaccine. The final concentration of the skimmed milk powder should be 5 g / litre.

Reference Table For Water Consumption

Water consumption is affected by environmental temperature, management conditions, and the age of pigs. The following table serves as a guideline.

Body weight

Water consumption per 100 pigs in a 4-hour period

Volume of stock solution to be prepared per 100 pigs1

4.5 Kg

11 L

85 mL

6.8 Kg

17 L

130 mL

9.0 Kg

23 L

175 mL

1Proportioner set at 30 mL per 4 litres (1 oz per gallon)

Manufactured for Prevtec microbia Inc.

3395 Casavant Blvd. West • Saint-Hyacinthe (Qc) • Canada • J2S 0B8 • Tel: 1+450-774-7000 • Fax: 1+450-774-8777

Manufactured by Saskatchewan Research Council

Saskatoon (SK) • Canada • Can. Vet. Bio. Est. Lic. No.: 57

PKI-RA-0015 v01

Code

Format

F18-F-200

200 doses

F18-F-500

500 doses

NAC No.: 1331001.0

PREVTEC MICROBIA INC
3395 CASAVANT BLVD. W, SAINT-HYACINTHE, QC, J2S 0B8
Telephone:   1-450-774-7000
Toll-Free:   1-866-774-7003
Order Desk:   1-800-773-7603
Fax:   1-450-774-8777
Website:   www.prevtecmicrobia.com
Email:   info@prevtecmicrobia.com
Every effort has been made to ensure the accuracy of the Coliprotec F18 information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2016 North American Compendiums. Updated: 2016-10-31

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