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Caseous D-T (Canada)

This page contains information on Caseous D-T for veterinary use.
The information provided typically includes the following:
  • Caseous D-T Indications
  • Warnings and cautions for Caseous D-T
  • Direction and dosage information for Caseous D-T

Caseous D-T

This treatment applies to the following species:
Company: Colorado Serum


This product has been shown to be effective for the vaccination of healthy sheep against tetanus, enterotoxemia associated with Clostridium perfringens Type D, and caseous lymphadenitis (CLA) associated with Corynebacterium pseudotuberculosis.

This product is a detoxified and purified whole culture of Corynebacterium pseudotuberculosis.

CLA is a chronic disease of sheep, goats, and other small ruminants in which clinical signs and lesions may not be seen for several months after infection. Causative bacteria can settle on skin, allowing exposure through wounds, then migrating to lymph nodes. Pulmonary transfer can also occur, especially in crowded conditions. CLA presents with both internal and external abscesses and lesions.

Clostridium tetani and Clostridium perfringens Type D are found in normal gut flora of farm animals. Tetanus occurs when the bacteria gains entry into wounds in unvaccinated animals. Overeating disease can occur in ruminants after overgrowth of Clostridium perfringens Type D occurs following an acidosis event from grain overload or ingestion of a high starch diet.

This product was licensed prior to the requirement to establish a minimum age for use. The duration of immunity is unknown. Safety in pregnant animals is unknown.

Directions For Use

Do not vaccinate within 21 days before slaughter. Shake well before use. Use entire contents when first opened. Store at 2°-8° C. Do not freeze. Do not mix with other products.

DOSAGE & ADMINISTRATION: Inject 2 ml subcutaneously in axillary space. Repeat in 4 weeks in opposite axillary space. Historically, annual vaccination of a single dose is recommended. Contact veterinarian for advice.


Anaphylactoid reaction may occur following administration of products of this nature. If noted, administer adrenalin or equivalent. Delayed treatment could result in an irreversible reaction. Following vaccination, slight lameness (soreness) in lambs may be observed, along with lethargy, in a percentage of the mature animals. It has also been shown that little or no benefit can be expected when animals with visible signs of the disease are vaccinated. Those showing infection should be disposed of or immediately culled from the flock and quarantined.

The vaccine will be ineffective if the vaccinating sheep already have the aforementioned diseases, and could make the condition worse.

This product is not recommend for goats, as previous safety studies showed a higher than accepted presence of fever and lethargy following vaccination.

In case of human exposure, consult a physician.

Contains thimerosal as a preservative.

Conveniently packaged in 10 dose and 50 dose sizes.


VLN: 188 / PCN: 7894.00

COLORADO SERUM COMPANY, 4950 York Street, Denver, Colorado 80216




Order #

20 ml

10 doses


100 ml

50 doses


CPN: 1174005.4

4950 YORK STREET, P.O. BOX 16428-0428, DENVER, CO, 80216-0428
Telephone:   303-295-7527
Order Desk:   800-525-2065
Fax:   303-295-1923
Every effort has been made to ensure the accuracy of the Caseous D-T information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2021 Animalytix LLC. Updated: 2021-10-04