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3. How to take Zantac 75
Adults and children aged 16 years and over: Swallow 1 tablet, with a drink
of water, as soon as you have symptoms.
If symptoms persist for more than one hour or return, take another tablet.
To prevent your symptoms, you can take 1 tablet half an hour to an hour
before eating or drinking.
Please read right through this leaflet before you start using this medicine. This
medicine is available without prescription, but you still need to use Zantac 75
carefully to get the best results from it.
• Keep this leaflet, you may need to read it again.
• If you have any questions, or if there is anything you do not understand, ask
your pharmacist.

If you take too many tablets

Contact your doctor or casualty department.

4. Possible side effects

Like all medicines, Zantac 75 can have side effects, but they are rare.

In this leaflet:

• Do not take more than 4 tablets in 24 hours.
• Do not take for longer than 2 weeks at a time.
• Do not take more than the recommended dose.

Stop taking the medicine and tell your doctor immediately if you experience:

What Zantac 75 does
Check before you take Zantac 75
How to take Zantac 75
Possible side effects
How to store Zantac 75
Further information

1. What Zantac 75 does

Zantac 75 is used to treat and prevent indigestion and heartburn for up to 12 hours.
The stomach produces acid which helps to digest food. Sometimes your stomach
produces too much acid which can cause indigestion and heartburn.
The active ingredient is ranitidine hydrochloride which is a medicine called an
'H2-blocker'. It works by preventing your stomach from producing too much acid.

2. Check before taking Zantac 75
Do not take Zantac 75:
• if you have ever had an allergic reaction to ranitidine or to any of the other
ingredients (listed in Section 6)
• if you are under 16 years.

Ask your doctor before you take this medicine:
• if you have kidney or liver problems
• if you have porphyria (too much of the pigment called porphyrin which may
discolour the urine)
• if you have unintended weight loss associated with acid indigestion
• if you are middle-aged or older with new or recently changed indigestion
• if you have persistent stomach pain
• if you are under regular medical supervision
• if you are elderly
• if you have breathing problems
• if you have a weak immune system
• if you suffer from diabetes.

If you are taking other medicines
Talk to your doctor or pharmacist before taking Zantac 75 if you are taking any
other medicines, including those obtained without a prescription; particularly
medicines to prevent blood clotting, such as warfarin, medicines for insomnia (e.g.
triazolam, midazolam), medicines for lowering blood glucose (e.g. glipizide),
medicines for fungal infections (e.g. ketoconazole, itraconazole, posaconazole),
medicines for treating HIV infection (e.g. atazanavir, delavirdine), medicines for lung
cancer (e.g. gefitnib) and non-steroidal anti-inflammatory painkillers (e.g. aspirin or
ibuprofen). This advice is even more important if you are elderly.

• Allergic reactions. These are very rare but may include developing an itchy rash,
swelling of the eyelids, face or lips (with or without a lumpy skin rash elsewhere
on the body), unexplained fever, difficulty breathing, dizziness (especially on
standing up) and chest pain or tightness.
• Unexplained bruising or bleeding, sore throat, mouth ulcers, fever, extreme
paleness, weakness or exhaustion. These can be signs of blood disorders such as
anaemia, low white blood cells, low platelet count, suppressed bone marrow or
reduction in agranulocytes (a type of white blood cell).
The following side effects may occur. Tell your doctor if you get them.
• Confusion, depression, drowsiness or hallucinations.
• Headache, dizziness or sudden, jerky movements.
• Changes in heart rhythm.
• Inflammation of your blood vessels.
• Sudden inflammation of your pancreas (you may get severe stomach pain)
or diarrhoea.
• Stomach pain, constipation, feeling sick (nausea).
• Inflammation of your liver which may cause one or more of the following: feeling
or being sick, fever, itching, yellowing of the skin and eyes, dark coloured urine.
This can cause changes to your liver function tests.
• Hair loss, blurred vision.
• Aches and pains in your muscles and joints.
• Sudden inflammation of your kidneys.
• Increase of serum creatine in the blood (kidney function test).
• Blood in your urine or changes in the normal amount of urine.
• Impotence.
• Swollen, tender or leaking breasts.
Reporting of side effects:
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any
possible side effects not listed in this leaflet. You can also report side effects directly
via the Yellow Card Scheme at: By reporting side
effects, you can help provide more information on the safety of this medicine.

5. How to store Zantac 75

Keep out of the reach and sight of children.
Do not use this medicine after the 'EXP' date shown on the pack. Store below 25°C.
Tablets should not be removed from blisters until immediatiately prior to use.

6. Further information

Active ingredients Each tablet contains Ranitidine Hydrochloride 84 mg (equivalent
to Ranitidine 75 mg). Other ingredients Microcrystalline cellulose, magnesium
stearate, hypromellose (E 464), titanium dioxide (E 171), red iron oxide (E 172) and
Packs of Zantac 75 contain 24 or 48 tablets.
The marketing authorisation holder is Omega Pharma Ltd., 32 Vauxhall Bridge Road,
London, SW1V 2SA, United Kingdom and all enquiries should be sent this address.
Manufactured by: Glaxo Wellcome SA, Aranda de Duero, Burgos, Spain or Omega
Pharma International, Venecoweg 26, B-9810 Nazareth, Belgium.
Zantac is a registered trademark of the GlaxoSmithKline group of companies and is
used under licence.

Pregnancy and breast feeding
Talk to your doctor before taking Zantac 75 if you are pregnant, trying to become
pregnant or are breast feeding.
LF03528E 62000000006107

This leaflet was revised in February 2016
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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.