XALATAN 0.005% EYE DROPS
Active substance(s): LATANOPROST / LATANOPROST / LATANOPROST
Xalatan® 0.005% Eye Drops
HOW TO USE XALATAN
Always use Xalatan exactly as your doctor or the doctor treating your child has told you. You should
check with your doctor or the doctor treating your child or pharmacist if you are not sure.
The usual dosage for adults (including the elderly) and children is one drop once a day in the affected
eye(s). The best time to do this is in the evening.
PACKAGE LEAFLET: INFORMATION FOR THE USER
This product is available using the name Xalatan 0.005% Eye Drops, but will be referred to as Xalatan
throughout this leaflet.
Do not use Xalatan more than once a day, because the effectiveness of the treatment can be reduced
if you administer it more often.
Read all of this leaflet carefully before you start using this medicine. Even if you have
already used Xalatan or a similar medicine before, we advise you to read this text carefully.
The information may have been changed.
Use Xalatan as instructed by your doctor or by the doctor treating your child until they tell you to stop.
Contact lens wearers
If you or your child wear contact lenses, they should be removed before using Xalatan. After using
Xalatan you should wait 15 minutes before putting the contact lenses back into the eye.
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or the doctor treating your child or your
This medicine has been prescribed for you or for your child. Do not pass it on to others. It may
harm them, even if their symptoms are the same as yours.
If any of the side effects get serious, or if you notice any side effects not listed in this leaflet,
please tell your doctor or the doctor treating your child or your pharmacist.
Instructions for use
Wash your hands and sit or stand comfortably.
Unscrew the protective cap. The protective cap should
Use your finger to gently pull down the lower eyelid of your
Place the tip of the bottle close to, but not touching your
Squeeze the bottle gently so that only one drop goes into
your eye, then release the lower eyelid.
Press a finger against the corner of the affected eye by the
nose. Hold for 1 minute whilst keeping the eye closed.
Repeat in your other eye if your doctor has told you to do this.
Put the protective cap back on the bottle.
What Xalatan is and what it is used for
Before you use Xalatan
How to use Xalatan
Possible side effects
How to store Xalatan
WHAT XALATAN IS AND WHAT IT IS USED FOR
Xalatan belongs to a group of medicines known as prostaglandin analogues. It works by increasing the
natural outflow of fluid from inside the eye into the bloodstream.
Xalatan is used to treat conditions known as open angle glaucoma and ocular hypertension in
adults. Both of these conditions are linked with an increase in the pressure within your eye, eventually
affecting your eye sight.
Xalatan is also used to treat increased eye pressure and glaucoma in all ages of children and babies.
BEFORE YOU USE XALATAN
Xalatan can be used in adult men and women (including the elderly) and in children from birth to 18
years of age. Xalatan has not been investigated in prematurely born infants (less than 36 weeks
Do not use Xalatan if you are
Allergic (hypersensitive) to latanoprost or any of the other ingredients of Xalatan (see section 6 for
the list of ingredients in your medicine)
Pregnant or trying to become pregnant
Take special care with Xalatan
Talk to your doctor or the doctor treating your child or your pharmacist before you take Xalatan or
before you give this to your child if you think any of the following apply to you or your child:
If you or your child are about to have or have had eye surgery (including cataract surgery)
If you or your child suffer from eye problems (such as eye pain, irritation or inflammation, blurred
If you or your child suffers from dry eyes
If you or your child have severe asthma or the asthma is not well controlled
If you or your child wear contact lenses. You can still use Xalatan, but follow the instruction for
contact lens wearers in Section 3
If you have suffered or are currently suffering from a viral infection of the eye caused by the
herpes simplex virus (HSV)
Taking other medicines
If you use Xalatan with other eye drops
Wait at least 5 minutes between using Xalatan and taking other eye drops.
If you use more Xalatan than you should
If you put too many drops into the eye, it may lead to some minor irritation in the eye and the eyes
may water and turn red. This should pass, but if you are worried contact your doctor or the doctor
treating your child for advice.
Xalatan may interact with other medicines. Please tell your doctor, the doctor treating your child or
pharmacist if you or your child are taking or have taken any other medicines including those medicines
(or eye drops) obtained without a prescription.
Do not use Xalatan when you are pregnant. Tell your doctor immediately if you are pregnant, think
you are pregnant, or are planning to become pregnant.
Do not use Xalatan when you are breast-feeding.
Driving and using machines
When you use Xalatan you might have blurred vision, for a short time. If this happens to you, do not
drive or use any tools or machines until your vision becomes clear again.
Contact your doctor as soon as possible if you or your child swallows Xalatan accidentally.
If you forget to use Xalatan
Carry on with the usual dosage at the usual time. Do not take a double dose to make up for the dose
you have forgotten. If you are unsure about anything talk to your doctor or pharmacist.
If you stop using Xalatan
You should speak to your doctor or the doctor treating your child if you want to stop taking Xalatan.
Very common effects (likely to affect more than 1 in 10 people):
Important information about some of the ingredients of Xalatan
Xalatan contains a preservative called benzalkonium chloride. This preservative may cause eye
irritation or disruption to the surface of the eye. Benzalkonium chloride can be absorbed by contact
lenses and is known to discolour soft contact lenses. Therefore, avoid contact with soft contact lenses.
If you or your child wear contact lenses, they should be removed before using Xalatan. After using
Xalatan you should wait 15 minutes before putting the contact lenses back in. See the instructions for
contact lens wearers in Section 3.
POSSIBLE SIDE EFFECTS
Like all medicines, Xalatan can cause side effects, although not everybody gets them.
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A gradual change in your eye colour by increasing the amount of brown pigment in the coloured
part of the eye known as the iris. If you have mixed-colour eyes (blue-brown, grey-brown, yellowbrown or green-brown) you are more likely to see this change than if you have eyes of one colour
(blue, grey, green or brown eyes). Any changes in your eye colour may take years to develop
although it is normally seen within 8 months of treatment. The colour change may be permanent
and may be more noticeable if you use Xalatan in only one eye. There appears to be no problems
associated with the change in eye colour. The eye colour change does not continue after Xalatan
treatment is stopped.
Redness of the eye.
Eye irritation (a feeling of burning, grittiness, itching, stinging or the sensation of a foreign body in
A gradual change to eyelashes of the treated eye and the fine hairs around the treated eye, seen
mostly in people of Japanese origin. These changes involve an increase of the colour (darkening),
length, thickness and number of your eye lashes.
Common effects (likely to affect less than 1 in 10 people):
Irritation or disruption to the surface of the eye, eyelid inflammation (blepharitis) and eye pain.
Uncommon effects (likely to affect less than 1 in every 100 people):
Eyelid swelling, dryness of the eye, inflammation or irritation of the surface of the eye (keratitis),
blurred vision and conjunctivitis.
Rare effects (likely to affect less than 1 in every 1000 people):
Inflammation of the iris, the coloured part of the eye (iritis/uveitis); swelling of the retina (macular
oedema), symptoms of swelling or scratching/damage to the surface of the eye, swelling around
the eye (periorbital oedema) misdirected eyelashes or an extra row of eyelashes, light sensitivity
Skin reactions on the eyelids, darkening of the skin of the eyelids.
Asthma, worsening of asthma and shortness of breath (dyspnoea).
Very rare effects (likely to affect less than 1 in 10,000 people):
Worsening of angina in patients who also have heart disease, chest pain, sunken eye appearance
(eye sulcus deepening).
Patients have also reported the following side-effects: fluid filled area within the coloured part of the
eye (iris cyst), headache, dizziness, palpitations, muscle pain, joint pain and developing a viral
infection of the eye caused by the herpes simplex virus (HSV).
Side effects seen more often in children compared to adults are: runny itchy nose and fever.
If any of the side effects become serious, or if you notice any side effects not listed in this leaflet,
please contact your doctor or pharmacist.
HOW TO STORE XALATAN
Before Xalatan is first opened keep it in a fridge (between 2°C and 8°C or 36°F and 46°F).
Once the bottle has been opened, it is not necessary to store it in the fridge; Xalatan can be kept at
normal room temperature (below 25º C / 77º F).
Keep all medicines out of the sight and reach of children.
Keep container in the outer carton to protect from light.
Each bottle should be thrown away four weeks after first opening.
The bottle label has an expiry date. Do not use after this date. The expiry date refers to the last day of
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to
dispose of medicines no longer required. These measures will help to protect the environment.
What Xalatan contains
The active substance is 0.005% (50micrograms/ml) latanoprost.
The other ingredients are: benzalkonium chloride, sodium chloride, sodium dihydrogen phosphate
monohydrate, disodium phosphate anhydrous and water for injections.
What Xalatan looks and contents of the pack
Xalatan is a clear, colourless eye drop solution.
Each bottle contains 2.5ml of solution.
This product is manufactured by: Pfizer Manufacturing Belgium NV, Rijksweg 12, Puurs, Belgium.
Procured from within the EU and repackaged by: Doncaster Pharmaceuticals Group Ltd., Kirk Sandall,
Doncaster, DN3 1QR.
Product Licence holder: BR Lewis Pharmaceuticals Ltd., Kirk Sandall, Doncaster, DN3 1QR.
PL No: 08929/0543
Leaflet revision and issue date (Ref): 22.04.13
Xalatan® is a registered trademark of Pfizer Ltd.
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Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.