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Active substance(s): ST JOHNS WORT DRY EXTRACT

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1. What this product is and what it is used for
2. Before you take this product
3. How to take this product
4. Possible side effects
5. How to store this product
6. Further information
This is a traditional herbal medicinal product containing
St John’s Wort extract. It is used to relieve the symptoms
of slightly low mood and mild anxiety. This is based on
traditional use only.
Do not take this product if:
• Your skin is exceptionally sensitive to sunlight (photosensitive)
• You are having light treatment (phototherapy) for any condition
• You are suffering from depression (see below)
• You are pregnant or breast-feeding
• You are allergic to any of the ingredients (see section 6)
• You are under the age of 18 years
Suffering from depression?
Symptoms of depression include feelings of helplessness and
hopelessness, loss of interest in daily activities, appetite or weight
changes, changes in sleep pattern, loss of energy and difficulty
concentrating. If your doctor has told you that you are suffering
from depression do not use this product. If you think that you
may be suffering from depression you should tell your doctor
before taking this product.
While you are taking this product:
• avoid excessive sunbathing or the use of sunbeds/solariums
• stop using it at least 10 days prior to undergoing any surgery
Driving or operating machines:
St John’s Wort may make you feel dizzy or sleepy.
If affected do not drive or use machinery.
Taking this product with other medicines
St John’s Wort can affect the way some medicines work and

Please read this information
carefully before you start
taking these tablets. It contains
some important information
about this product. Keep this
leaflet with the tablets. You may
want to read it again or show
it to your doctor, pharmacist or
refer to a qualified healthcare
reduce their effectiveness. Medicines that can be affected by St
John’s Wort include prescription medicines, and those that you
may have bought without a prescription. Therefore it is important
that you do not take St John’s Wort if you are using any of the
medicines listed in the table below.
All hormonal contraceptives: The birth control ‘Pill’, emergency
contraception (also known as the ‘morning after pill’), hormonal
implants, creams, patches, intra-uterine devices with hormones.
All medicines for depression/anxiety: Amitriptyline, clomipramine,
moclobemide, citalopram, escitalopram, fluoxetine, fluvoxamine,
paroxetine, sertraline, duloxetine, venlafaxine.
All hormonal replacement therapy (HRT) treatments: HRT tablets,
patches, gels, vaginal rings
All medicines for thinning the blood (anticoagulants): Warfarin,
All medicines for epilepsy: Carbamazepine, phenobarbitone,
phenytoin, primidone, sodium valproate
All immunosuppressant medicines: Ciclosporin, tacrolimus
All medicines for HIV infections: Amprenavir, atazanavir, darunavir,
fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir,
tipranavir, efavirenz, nevirapine, delavirdine
Some medicines for cholesterol: Simvastatin, atorvastatin
Some medicines for cancer: Irinotecan, dasatinib, erlotinib,
imatinib, sorafenib, sunitinib, etoposide, mitotane
Some medicines for heart disease: Digoxin, ivabradine, amiodarone
Some medicines for migraines: Almotriptan, eletriptan, frovatriptan,
naratriptan, rizatriptan, sumatriptan, zolmitriptan
Some medicines for high blood pressure: Amlodipine, nifedipine,
felodipine, verapamil
A medicine for regulating mood: Lithium
A thyroid hormone: Thyroxine



Taking this product with other medicines (continued)
St John’s Wort may also affect the following medicines. Therefore
do not take this product with these medicines unless a doctor has
said it is safe to do so:
• fentanyl, propofol, sevoflurane and midazolam
(anaesthetics/pre-operative medicines)
• tramadol (an analgesic)
• erythromycin, clarithromycin and telithromycin (antibiotics)
• itraconazole and voriconazole (antifungals)
• artemether and lumefantrine (antimalarials)
• rasagiline (an anti-Parkinson’s medicine)
• aripiprazole (an antipsychotic medicine)
• buspirone (an anxiolytic)
• aprepitant (used to treat post-operative vomiting)
• butobarbital and phenobarbital (barbiturates)
• methyl phenidate (a central nervous system or CNS stimulant)
• exemestane (a hormone antagonist)
• eplerenone (a diuretic)
• lansoprazole and omeprazole (proton pump inhibitors)
• theophylline (a bronchodilator)
• gliclazide (an antidiabetic medicine)
Adults and the elderly
Take 1 tablet daily. Swallow the tablets whole with some water or
other liquid. Do not chew. Do not exceed the stated dose.
If you take too much of this product (overdose)
If you take more than the recommended dose, speak to a doctor,
pharmacist or qualified healthcare practitioner and take this leaflet
with you.
If you forget to take this product
Continue to take your usual dose at the usual time, it does not matter
if you have missed a dose.
If you have any questions, or are unsure about anything, please
ask your doctor, pharmacist or qualified healthcare practitioner.
Like all medicines, this product can have side effects. The following
side effects have been reported:
• gastrointestinal disorders such as indigestion, loss of appetite,
nausea, diarrhoea and constipation.
• fatigue and restlessness.
allergic skin reactions such as rash, hives or itching of
the skin. If you experience allergic skin reactions, stop taking the
product and consult your doctor.
Also sunburn-like reactions on skin exposed to strong sunlight or
strong ultra-violet (UV) irradiation e.g. solarium have been reported,
particularly in fair skinned individuals. Other side effects that have
been reported include headaches, nerve pain or tingling, anxiety,
dizziness and mania. The frequency of these effects occurring
is not known.

You must speak to a doctor or qualfied healthcare practitioner
if your symptoms worsen, if they do not improve after six
weeks, or if any of the side effects become serious or if you
notice any side effects not mentioned in the leaflet.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in the package
leaflet. You can also report side effects directly via the Yellow Card
Scheme at By reporting side
effects you can help provide more information on the safety of
this medicine.
Do not use your tablets after the expiry date. The expiry date is
printed on the box and the blister pack. The expiry date refers to the
last day of that month.
Do not store above 25°C. Store in the original packaging.
Keep the tablets out of sight and reach of children.
Keep your tablets in the packaging until it is time to take them.
Medicines should not be disposed of via waste water or household
waste. Ask your pharmacist how to dispose of medicines no longer
required. These measures will help protect the environment.
Each film coated tablet contains 425mg of extract
(as dry extract) from St John’s Wort aerial parts (Hypericum
perforatum L.) (5-7:1) (equivalent to 2125mg – 2975mg of
St John’s Wort). Extraction Solvent: Ethanol 60% V/V.
This product also contains the following ingredients:
Excipients in the extract
Maltodextrin, Silica Colloidal Anhydrous
Tablet Core
Maltodextrin, Microcrystalline cellulose, Croscarmellose Sodium,
Stearic Acid, Magnesium Stearate, Silica Colloidal Anhydrous
Tablet Coating
Hypromellose, Red Iron Oxide (E172), Titanium Dioxide (E171),
The tablets are red coated and oval shaped.
This product is available in 30, 60 and 90 tablets. Not all pack
sizes are marketed.
If you would like further information about this product or for
large print, Braille or audio version please contact:
Traditional Herbal Registration Holder: Vitabiotics Ltd, 1 Apsley
Way, London NW2 7HF. Telephone: 020 8955 2662
Manufacturer: Thompson & Capper Ltd, Hardwick Road,
Astmoor, Runcorn, Cheshire WA7 1PH. Traditional Herbal
Registration Number: THR 00387/0055
This leaflet was revised in September 2016.



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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.