VISTAPHENICOL EYE DROPS
Active substance(s): CHLORAMPHENICOL / CHLORAMPHENICOL / CHLORAMPHENICOL
Chloramphenicol 0.5% Eye Drops
Read all of this leaﬂet carefully before you start using this medicine because it contains
important information for you.
• Keep this leaﬂet. You may need to read it again
• If you have any further questions, please ask your doctor or pharmacist
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even
if their signs of illness are the same as yours
• If you get any side eﬀects, talk to your doctor or pharmacist. This includes any possible side eﬀects
not listed in this leaﬂet. See section 4
What is in this leaﬂet:
1. What Chloramphenicol Eye Drops are and
what they are used for
2. What you need to know before you use
Chloramphenicol Eye Drops
3. How to use Chloramphenicol Eye Drops
4. Possible side eﬀects
5. How to store Chloramphenicol Eye Drops
6. Contents of the pack and other information
1. What Chloramphenicol Eye
Drops are and what they are
Chloramphenicol belongs to a group of
medicines called antibiotics. An antibiotic is
a medicine which is used for the treatment
of a variety of infections caused by bacteria.
Chloramphenicol Eye Drops are used in both
adults and children for the treatment of a wide
range of eye infections caused by bacteria.
2. What you need to know before you
use Chloramphenicol Eye Drops
Do not use Chloramphenicol Eye Drops if:
• you are allergic to chloramphenicol or any of
the other ingredients of this medicine listed
in section 6
Warnings and precautions
Talk to your doctor or pharmacist before using
Chloramphenicol Eye Drops if:
• you have visual disturbances
• you have severe pain in the eye
• you are sensitive to light
• your eye is inﬂamed and you have a
rash on the scalp or face
• your eye looks cloudy
• your black or coloured part of the eye
• you have a foreign body in the eye
• you have an eye infection that keeps
• you have glaucoma (raised pressure
in the eye)
• you have dry eyes
• you have eye injury or eye surgery
• you are currently using any other eye
drops or eye ointment
Other medicines and Chloramphenicol Eye
Tell your doctor or pharmacist if you are using,
have recently used or might use any other
In particular, tell your doctor if you are taking
any of the following:
• medicines for cancer such as methotrexate
• medicines for the immune system such as
• the dietary supplement chymotrypsin
Pregnancy and breast-feeding
Chloramphenicol should not be used during
pregnancy and breast-feeding unless
considered essential by your doctor, as the
eﬀects are unknown.
If you are a pregnant or breast-feeding, think
you may be pregnant or are planning to have a
baby, ask your doctor or pharmacist for advice
before using this medicine.
Chloramphenicol eye drops contain
phenylmercuric nitrate as a preservative which
may cause allergic reaction. Do not wear contact
lenses during treatment.
8. Repeat in the other eye if you have been
told to use Chloramphenicol Eye Drops in
9. Replace the outer cap on the container,
trying not to touch the applicator tip with
anything, including the eye or the ﬁngers
10. Wash your hands.
Use in children:
Dosage adjustment may be necessary in
newborn infants to reduce the risk of adverse
eﬀects. The maximum duration of treatment is
How much to use
One to two drops should be applied to each
aﬀected eye up to six times daily or more
frequently if required. Severe infections
may require one or two drops every ﬁfteen
to twenty minutes initially; reducing the
frequency of use as the infection is controlled.
Prolonged use of Chloramphenicol Eye Drops is
not advisable. You should not use this product
for longer than 5 days at a time unless your
doctor has told you otherwise.
If you use more chloramphenicol than you
Chloramphenicol Eye Drops are for external use
only. If you suspect someone has swallowed
any Chloramphenicol Eye Drops, contact your
doctor or go to the accident and emergency
department of your local hospital at once.
Always take the container with you, if possible,
even if empty.
Driving and using machines
Chloramphenicol Eye Drops can cause
temporary blurring of vision after application.
Wait until your vision is clear before driving or
If you accidentaly apply too much drops, you
should wash your eye with plenty of water, if
any painful symptoms continue after this, you
should tell your doctor immediately.
3. How to use Chloramphenicol Eye
If you forget to use Chloramphenicol Eye
Try not to miss doses. If you do miss a dose, do
not worry, just carry on as normal. Do not use
extra drops to make up.
Always use this medicine exactly as your doctor
or pharmacist has told you. Check with your
doctor or pharmacist if you are not sure.
Contact lenses should be taken out before
treatment with Chloramphenicol Eye Drops.
Instructions for use
1. Wash your hands well before use
2. Remove the outer cap. You may ﬁnd it
easier to apply your drops in front of a
3. Tilt the head back and pull the lower lid of
the eye out to form a pocket
4. Hold the container between the thumb and
middle ﬁnger of the other hand, turn the
container upside down near to the eye, try
not to touch the eye with the nozzle
5. Apply enough pressure to
the container to release one
to two drops
6. Blink the eye a few times
7. If you think that you have
missed the eye, then insert
4. Possible side eﬀects
Like all medicines, this medicine can cause side
eﬀects, although not everyone gets them.
Stop using your medicine and tell your doctor or
pharmacist immediately if you experience the
following side eﬀects:
• Wheeziness (shortness of breath), fever,
swelling of your face, lips or tongue, itching
or rash with swelling of skin (the rash could
be puﬀy (swollen) or blotchy, or look like little
• A sore throat, bruising or being unable
to overcome an infection. On very rare
occasions, patients using chloramphenicol
have had changes in their blood cells causing
severe tiredness or easy bruising
Possible side eﬀects include:
• inﬂammation of the skin (dermatitis).
100mm Measurement Veriﬁcation Bar
Rare side eﬀects include:
• damage to parts of the eye
• bone marrow depression (a condition where the
marrow is unable to produce red blood cells)
• a reduced production and death of red blood
Reporting of side eﬀects
If you get any side eﬀects, talk to your doctor,
pharmacist or nurse. This includes any possible
side eﬀects not listed in this leaﬂet. You can
also report side eﬀects directly via the Yellow
Card Scheme: www.mhra.gov.uk/yellowcard. By
reporting side eﬀects you can help provide more
information on the safety of this medicine.
5. How to store Chloramphenicol
Keep out of the sight and reach of children.
Do not use Chloramphenicol Eye Drops after the
expiry date printed on the bottle label. The expiry
date refers to the last day of the month. Once you
have opened the bottle use within 4 weeks.
You are advised to dispose of the bottle once you
have ﬁnished your 5 day course of treatment.
This medicine needs to be stored upright between
2-8°C (in a refrigerator). Protect from light. Do not
allow it to freeze.
Medicines should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of medicines no longer
required. These measures will help to protect the
6. Contents of the pack and other
What Chloramphenicol Eye Drops contains
The active ingredient is Chloramphenicol 0.5%
The other ingredients are Puriﬁed Water, Boric
Acid, Borax and Phenylmercuric Nitrate 0.002%
What Chloramphenicol Eye Drops look like
and contents of the pack
Chloramphenicol Eye Drops are supplied in
plastic bottles, each bottle containing 10ml of
Marketing Authorisation Holder:
Martindale Pharmaceuticals Ltd.
Bampton Road, Romford, RM3 8UG, England
Via G.B. Oliva 6/8
56121 Pisa, Italy
If you would like any more information, or
would like the leaﬂet in a diﬀerent format,
please contact Medical Information at the
Product Licence Numbers: PL 00156/0048
HK – 09064
This leaﬂet was last updated February 2017
PACKAGE LEAFLET: INFORMATION FOR THE USER
Chloramphenicol 0.5% PIL UK PL
00156/0048 Eye drops
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.