Skip to Content


Active substance(s): RIMEXOLONE

View full screen / Print PDF » Download PDF ⇩
Vexol ® 1% Eye Drops

Ref: 0544/170216/1/F

Patient Information Leaflet
Read all of this leaflet carefully before you start
using this medicine, because it contains
important information for you.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your
doctor or your pharmacist.
• This medicine has been prescribed for you only.
Do not pass it on to others. It may harm them,
even if their signs of illness are the same as
• If you get any of the side effects, talk to your
doctor or pharmacist. This includes any possible
side effects not listed in this leaflet. See section 4.
Your medicine is called Vexol 1% Eye Drops,
throughout the remainder of this leaflet it will be
referred to as Vexol
What is in this leaflet
1 What Vexol is and what it is used for
2 What you need to know before you use Vexol
3 How to use Vexol
4 Possible side effects
5 How to store Vexol
6 Contents of the pack and other information


What Vexol is and what it is used for

Vexol belongs to a group of medicines known as
It is used to prevent or treat eye inflammation
following surgery of the eye and to treat
inflammation of the eye surface and the front portion
inside the eye (anterior segment).
It helps to relieve the symptoms of inflammation
such as redness, soreness and swelling.

2 What you need to know before you use

Do not use Vexol...
• If you have any type of infection of the eye that
is not being treated. Use of steroids may make
infections worse.
• If you have a red eye that has not been seen by a
• If you are allergic to rimexolone or any of the
other ingredients listed in section 6.

Pregnancy and breast-feeding
If you are pregnant or might get pregnant, or if you
are breast-feeding a baby, talk to your doctor
before you use Vexol.
Driving and using machines
If your vision is blurred or your sight is affected in
any way following the use of Vexol, you should not
drive or operate machinery until your vision is
Other medicines and VEXOL
Tell your doctor or pharmacist if you are taking or
have recently taken any other medicines, including
medicines obtained without a prescription.
If you are using more than one eye preparation,
wait 15 minutes between each application.
Important information if you wear Contact
Wearing contact lenses is not advisable during
treatment of an eye inflammation as it may make
your condition worse.
Do not use the drops while wearing contact
lenses. Wait at least 15 minutes after use before
putting your lenses back in. There is a preservative
in Vexol (benzalkonium chloride) that can discolour
soft contact lenses and may cause eye irritation.


How to use Vexol

The usual dose
This will depend on the reason for use.
Inflammation (red, painful eye)
Apply 1 drop in the affected eye 4 times a day or
more often, if advised by your doctor.
Inflammation of the inside of the eye (Uveitis)
1st week - Apply 1 drop in the affected eye every
hour while awake.
2nd week - Apply 1 drop every 2 hours while awake.
3rd week - Apply 1 drop 4 times a day.
4th week - Apply 1 drop twice daily for the first 4
days and then apply 1 drop once daily for the last 3
Inflammation after eye surgery
Apply 1 drop in the affected eye 4 times a day,
beginning 24 hours after your operation and
continuing for the first 2 weeks afterwards.

Ask your doctor for advice.

Not for use in CHILDREN.

Vexol is not for use in CHILDREN.

Remove the loose collar from the cap when the
bottle is first opened.

Take special care...
• If you have a disorder causing a thinning of the
eye tissues, such as rheumatoid arthritis,
Fuch's dystrophy or following a corneal
transplant. Steroids may cause further thinning
and possible perforation.
• Steroids applied to the eye may delay the healing
of your eye wound.
You may still be able to use Vexol, but discuss it
with your doctor first.

Always use Vexol exactly as your doctor has told
you. You should check with your doctor or
pharmacist if you are not sure.

How to use
• Wash your hands before
you start.
• Shake the bottle well.
• Twist off the bottle cap.
• Hold the bottle pointing
down, between your
thumb and fingers.
• Tilt your head back.
• Pull down your lower
eyelid with a finger, until
there is a 'pocket'
between the eyelid and
your eye. The drop will go
in here (picture 1).
• Bring the bottle tip close
to the eye. Do this in front
of a mirror if it helps.
• Do not touch your eye
or eyelid, surrounding areas or other surfaces
with the dropper. It could infect the drops.
• Gently press on the base of the bottle to release
one drop at a time (picture 2).
• Do not squeeze the bottle, only a gentle press
on the bottom is needed.
• If you use drops in both eyes, repeat the steps for
your other eye. Put the bottle cap firmly back on
immediately after use.
• If a drop misses your eye, try again.
• If you forget to use Vexol, just use it as soon as
possible. However, if it is almost time for your
next dose, skip the missed dose and go back to
your normal dosing schedule. Do not take a
double dose to make up.
• If you use more Vexol than you should, it can
be washed out with luke warm water.
• If treatment with Vexol is stopped…
A flare-up of inflammation may occur if treatment
is discontinued early. Do not suddenly stop using
the product without your doctor's advice. Your
doctor may want to gradually reduce the amount
you use to reduce the chance of unwanted
If you have any further questions on the use of
Vexol, ask your doctor or pharmacist.

Rare ( 1 in 10 users in 10,000 ): Allergy, low blood
pressure, runny nose.
Not known ( cannot be estimated from the
available data ): Chest pain.
If VEXOL is used for a long time this can lead to
an increase in pressure inside the eye or the
formation of cataracts, both of which can lead to
decreased vision. It can also lead to infections, as
your natural resistance to these is reduced. The
risk of VEXOL induced increased pressure inside
the eye may be greater in children and may occur
earlier than in adults. VEXOL is not approved for
use in children.
If any of the side effects get serious, or you notice
any side effects not listed in this leaflet, tell your
doctor or pharmacist.
Reporting of side effects
If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report
side effects directly via the Yellow Card Scheme at
By reporting side effects, you help provide more
information on the safety of this medicine.

Do not use this medicine after date shown on the
carton label on or bottle. Only keep this medicine if
your doctor tells you to. If your eye drops become
discoloured or show any other signs of deterioration,
consult your pharmacist (chemist) who will tell you
what to do.
• Do not store above 30°C.
• Do not freeze.
• Once the bottle has been opened then the eye
drops must be discarded one month after first

Possible side effects

Like all medicines, Vexol can cause side effects,
although not everybody gets them.

You may experience some or all of the
following effects in your eye(s):

Common ( affect 1 to 10 people in 100 ): Blurred
vision, discharge, discomfort.
Uncommon ( affect 1 to 10 people in 1000 ):
Redness of the eye or inside the eyelid, pain,
itching, dry eyes, swelling, watery eyes, eye
staining, irritation, serious infections, increased
pressure in the eye, eye surface inflammation or
other disorders.
Rare ( 1 to 10 users in 10,000 ): Swelling of the
back of the eye, eyelid swelling, sensitivity to
light, crusting on the eyelids or scarring or other
Not known ( cannot be estimated from the
available data ): Reduced vision.

How to store Vexol

You may also experience effects in other
areas of your body including:

Uncommon ( affect 1 in 10 people in 1000 ):
Headache, redness or soreness of the throat, bad
or unusual taste.

Contents of the pack and other

What Vexol contains
Vexol contains 10mg/ml of rimexolone as the active
ingredient. Vexol also contains benzalkonium
chloride, mannitol, carbomer, polysorbate 80,
sodium chloride, disodium edetate, sodium
hydroxide, hydrochloric acid, purified water.
What Vexol looks like and contents of the pack
Vexol is a white to off-white suspension in a plastic
dropper bottle.
Vexol is available in bottles of 5ml of solution.
Manufacturer and Licence Holder
Vexol is manufactured by Alcon Cusi, S.A C/Camil
Fabra 58, 08320 EI Masnou-Barcelona, Spain and
is procured from within the EU and repackaged by
the Product Licence Holder: Lexon (UK) Limited,
Unit 18, Oxleasow Road, East Moons Moat,
Redditch, Worcestershire, B98 0RE.


PL 15184/0544

Leaflet revision date: 17/02/16

Blind or partially sighted?
Is this leaflet hard to see or read?
Phone Lexon (UK) Limited,
Tel: 01527 505414 for help.
Ref: 0544/170216/1/B

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.