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TRANYLCYPROMINE 10 MG COATED TABLETS

Active substance(s): TRANYLCYPROMINE

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PATIENT INFORMATION LEAFLET

Parnate® 10mg Coated Tablets

Revision Date: 16.08.2016
Leaflet Reference: PAR10

(tranylcypromine)
Your medicine is known by the above name, but will be referred to as
Thoughts of suicide and worsening of your depression or anxiety
Parnate® 10mg Tablets throughout this leaflet.
disorder:
If you are depressed and/or have anxiety disorders, you can
sometimes have thoughts of harming or killing yourself (see section 4
Read all of this leaflet carefully before you start taking this
‘Possible side effects’). These may be increased when first starting
medicine because it contains important information for you.
antidepressants, since these medicines all take time to work, usually
Keep this leaflet. You may need to read it again.
about two weeks but sometimes longer.
If you have any further questions, ask your doctor or pharmacist.
This medicine has been prescribed for you. Do not pass it on to others.
You may be more likely to think like this if you:
It may harm them, even if their signs of illness are the same as yours.

have previously had thoughts about killing or harming yourself.
If you get any side effects, talk to your doctor or pharmacist. This

are a young adult. Information from clinical trials has shown an
includes any possible side effects not listed in this leaflet.
increased risk of suicidal behaviour in adults aged less than 25
years with psychiatric conditions who were treated with an
What is in this leaflet:
antidepressant.
®
1. What Parnate 10mg Tablets are and what they are used for
2. What you need to know before you take Parnate® 10mg Tablets
If you have thoughts of harming or killing yourself, at any time, contact
3. How to take Parnate® 10mg Tablets
your doctor or go to a hospital straight away. You may find it helpful to
4. Possible side effects
tell a relative or close friend that you are depressed or have an anxiety
5. How to store Parnate® 10mg Tablets
disorder, and ask them to read this leaflet. You might ask them to tell
6. Contents of the pack and other information
you if they think your depression or anxiety is getting worse, or if they
are worried about changes in your behaviour.
1. WHAT PARNATE® 10MG TABLETS ARE AND WHAT THEY ARE
Children and adolescents
USED FOR
Parnate® 10mg Tablets is not recommended for children under 18
®
years old (see section 3 ‘Use in children and adolescents’).
Parnate 10mg Tablets contain the active substance tranylcypromine
which belongs to a group of antidepressant medicines known as
Other medicines and Parnate® 10mg Tablets
monoamine oxidase inhibitors (MAOIs). It works by stopping the
breakdown of two substances in the brain called serotonin and
Please tell your doctor or pharmacist if you are taking, have recently
noradrenaline. Your medicine should help bring these substances back
taken or might take any other medicines, including medicines obtained
to normal levels.
without a prescription.
This medicine is used to treat moderate to severe depression in adults.
DO NOT take Parnate® 10mg Tablets with the following
It can also help you if you are having feelings of fear (phobia) which
medicines:
sometimes occurs in depression. This medicine is often used when

Medicines called sympathomimetic agents - these include
other types of antidepressant medicines have not worked.
ephedrine, pseudoephedrine, adrenaline and noradrenaline (these
may be found in medicines used to treat heart problems and
asthma as well as some decongestants and cough/cold remedies)
2. WHAT YOU NEED TO KNOW BEFORE YOU TAKE PARNATE®

Bupropion, a medicine to help you stop smoking
10MG TABLETS

medicines to control appetite, e.g. amphetamine and fenfluramine

medicines that treat Parkinson’s disease, e.g. levodopa
Do not take Parnate® 10mg Tablets if:

dopamine, a medicine used to treat certain heart conditions

You are allergic to tranylcypromine or any of the other ingredients

the pain killers pethidine and nefopam
of this medicine (listed in section 6)

general anaesthetics such as propofol, which are used in surgery

You are taking other MAOIs or have taken other MAOIs within the

other medicines used to treat depression (e.g. amitriptyline,
last two weeks
imipramine, tryptophan)

You have taken clomipramine or imipramine within the last three

buspirone, used to treat anxiety.
weeks or are planning to take them within the next three weeks

You suffer from porphyria (which is an inherited disease affecting
Parnate® 10mg Tablets must be taken with caution if you are
the nervous system and skin)
taking the following medicines:

You have severe heart disease or any disease of the blood

other MAOIs such as isocarboxazid
vessels of the brain

strong pain killers e.g. codeine

You have pheochromocytoma which is a tumour of the adrenal

medicines to treat seizures/fits, e.g. carbamazepine
glands (glands near the kidneys) causing high blood pressure

barbiturates used to treat severe sleeping problems, e.g.

You have been diagnosed with an overactive thyroid gland (a
amylobarbitone
gland in the neck)

SSRIs such as fluoxetine or sertraline (for depression). Taking

You have known liver damage or a disorder affecting the blood
your medicine with these products may cause the following serious
cells (your doctor will know)
side effects: sweating, extreme agitation, confusion, muscle

You are taking any of the medicines listed under ‘Do not take’ in
stiffness
the Other Medicines and Parnate® 10mg Tablets section of this

medicines for high blood pressure (e.g. guanethidine, reserpine,
leaflet.
methyldopa)

Please tell your doctor if any of the above apply to you, and do not

medicines to treat diabetes (e.g. insulin, metformin)
take Parnate® 10mg Tablets.

antihistamines used to treat allergies, e.g. cetirizine.
Warnings and precautions
Consult your doctor before you take Parnate® 10mg Tablets if you are
taking or might be taking any of these.
Talk to your doctor or pharmacist before taking this medicine if






you:

Parnate® 10mg Tablets with food, drink and alcohol

are elderly
have a mild heart problem which restricts your activity
suffer from seizures/fits (epilepsy)
are due to have surgery in the next few weeks
have a history of dependence on drugs or alcohol.
Even though some of the above may be obvious, it is important that
your doctor is aware if any of them apply to you.

You should NOT take alcohol (especially red wine) whilst you are
taking Parnate® 10mg Tablets. This includes non-alcoholic beer or
lager.
Parnate® 10mg Tablets stops the breakdown of a substance called
tyramine which is found in large amounts of certain foods. If this
substance is not broken down, it can cause very high blood pressure.

1

So, whilst you are taking Parnate® 10mg Tablets, you should avoid the
following foods:

Matured cheeses (e.g. cheddar or processed cheese made from
mature cheese)

Yeast extracts (e.g. Bovril or Marmite)

Meat, fish or poultry which is not fresh or has been pickled

Broad bean pods

Banana skins.

such as nausea (feeling sick), vomiting (being sick), sweating and
difficulty in sleeping. If you have any further questions on the use of
this medicine, ask your doctor or pharmacist.

6. CONTENTS OF THE PACK AND OTHER INFORMATION

4. POSSIBLE SIDE EFFECTS

Each tablet contains tranylcypromine sulphate equivalent to 10mg of
tranylcypromine base.
Parnate® 10mg Tablets also contain sucrose, maize starch, calcium
sulphate dihydrate (E516), carmellose sodium, magnesium stearate
(E470b). The coating contains gelatin, sucrose, docusate sodium,
purified talc (E553b), light kaolin (E559), calcium carbonate (E170),
ethylcellulose, acacia (E414), carmoisine (E122), ponceau 4R (E124),
maize starch, titanium dioxide (E171), carnauba wax (E903) and edible
ink [shellac, iron oxide black (E172), soya lecithin (E322) and trace
amounts of dimethyl siloxane].

Like all medicines, Parnate® 10mg Tablets can cause side effects,
although not everybody gets them.
If you eat foods or take medicines which interact with the active
ingredient tranylcypromine, you may get very high blood pressure (a
hypertensive crisis).
If you notice any of the following symptoms please see your doctor
immediately:

frequent or throbbing headaches, painful or stiff neck, changes in
heart rate, pain in the middle of the chest, feeling sick or being
sick, sweating, paleness, or flushing of the skin and enlarged
pupils which may make bright sunlight uncomfortable. Although
very rare, there may be muscle weakness or paralysis (loss of
movement) down one side of the body and there have been a few
deaths from hypertensive crisis.

thoughts of suicide and suicidal behaviour early on in treatment or
shortly after stopping treatment (see section 2 ‘Thoughts of suicide
and worsening of your depression or anxiety disorder’).

Pregnancy and breast feeding
If you are pregnant or breast-feeding, think you may be pregnant or
planning to have a baby, ask your doctor or pharmacist for advice
before taking this medicine.
Parnate® 10mg Tablets should NOT be used during pregnancy or
breast feeding unless your doctor thinks it is essential. This medicine
may pass into breast milk.
Your doctor will decide whether you should ablactate (gradually
reduce) or stop therapy with Parnate® 10mg Tablets. Effects of
Parnate® 10mg Tablets on fertility are unknown.
Driving and using machines
Parnate® 10mg Tablets may make you feel drowsy or dizzy or affect
your concentration. You should not drive or use machines when you
first start to take this medicine until you are certain that you are not
getting these side effects. If in any doubt, speak to your doctor before
you drive or use machines.

Sometimes patients feel anxious whilst taking this medicine and rarely
some patients will become very agitated or irritable. Your doctor may
reduce your dose if this happens.
Some patients get low blood pressure and may feel dizzy on standing
up. If this continues for a long time, your doctor may stop your
medicine.
Other side effects which may occur include:

difficulty in sleeping, mild headache, sleepiness, weakness,
dizziness, fast heart beat (palpitations), restlessness, dry mouth,
blurred vision, feeling sick, water retention or swelling, weight gain,
increased appetite, rash and difficulty in passing water.

Important information about some of the ingredients of Parnate®
10mg Tablets
This medicine also contains carmoisine (E122) and Ponceau 4R
(E124) which may cause allergic reactions.
This medicine also contains sucrose (a sugar). If you have been told
by your doctor that you have an intolerance to some sugars, contact
your doctor before taking this medicine.
3. HOW TO TAKE PARNATE® 10MG TABLETS
Always take this medicine exactly as your doctor has told you. Do NOT
take more than your doctor tells you to. Check with your doctor or
pharmacist if you are not sure.

What Parnate® 10mg Tablets contain:

What Parnate® 10mg Tablets look like and contents of the pack
Parnate® 10mg tablets are bi-convex, geranium-red sugar-coated
tablets marked with “FW 251” on one side. The tablets are in white
plastic containers with a cap and a security tag containing a desiccant
cartridge.
Parnate ® 10mg Tablets are available in containers of 28 tablets.
Who manufactured your medicine
Parnate® 10mg tablets are manufactured by Dales Pharmaceuticals
Ltd., Snaygill Industrial Estate, Keighly Road, Skipton, North Yorkshire,
BD23 2RW, UK. Procured from within the EU and repackaged by
Product Licence Holder: Beachcourse Limited, 20 Alliance Court,
Alliance Road, London W3 0RB.

PL
16378/0551
Revision date: 16.08.2016

POM

Leaflet reference: PAR10

Rarely some patients experience soreness in the hands and feet,
which may be a sign of inflamed nerves.
Rarely, some patients may find the relief of their depression decreases
with time and higher doses of the active ingredient, tranylcypromine,
are needed to get the same effect.

Swallow the tablets whole with a glass of water.
The recommended dose for adults is:
One tablet in the morning and one tablet in the afternoon each day
Try to take the last dose before 3 o’clock in the afternoon
This dose may be increased by your doctor to three tablets a day.
Take the extra tablet at mid-day

If you are elderly your doctor will usually prescribe you a lower
dose.
When you start to feel better, your doctor may change your dose to
one tablet a day.
Do NOT take more than three tablets each day unless your doctor tells
you to.




Very rarely, liver problems (symptoms include yellowing of the skin and
the whites of the eyes), bruising and changes in blood have been
reported. Therefore, if you get a bad sore throat or high fever or
become very tired and pale or notice bruises and nose bleeds, tell your
doctor.
Reporting of side effects

Parnate® 10mg Tablets are not recommended for children under 18
years old (see section 2 ‘Children and adolescents’).

If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You can
also report side effects directly via the Yellow Card Scheme at:
www.mhra.gov.uk/yellowcard.
By reporting side effects, you can help provide more information on the
safety of this medicine.

If you take more Parnate® 10mg Tablets than you should:

5. HOW TO STORE PARNATE® 10MG TABLETS

Use in children and adolescents

If you think that you, or any other person, have taken too many tablets,
contact your doctor or hospital casualty department immediately. Take
any remaining tablets and this leaflet with you so that the medical staff
know exactly what you have taken.

Keep this medicine out of the sight and reach of children.
Do not use Parnate® 10mg Tablets after the expiry date which is stated
on the carton and label after EXP. The expiry date refers to the last
day of that month.
If your tablets are out of date, take them to your pharmacist who will
get rid of them safely.
Do not store above 25°C Store in original container in order to protect
from light and moisture. Replace cap tightly after use.
Medicines should not be disposed via wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer required.
These measures will help to protect the environment.

If you forget to take your Parnate® 10mg Tablets:
If you miss a dose, wait until your next dose. Do not take the dose you
have missed. You can then carry on as before. Do not take more than
one dose at a time.
If you stop taking Parnate® 10mg Tablets
Continue to take Parnate® 10mg Tablets even if you no longer feel ill.
DO NOT STOP taking this medicine without talking with your doctor
first, especially if you have taken large doses for a long time.
When the time comes to stop your doctor will probably decrease your
dose gradually as stopping the tablets suddenly may cause ill-effects

2

3

PATIENT INFORMATION LEAFLET

Tranylcypromine 10mg Coated Tablets
Your medicine is known by the above name, but will be referred to as
Tranylcypromine 10mg Tablets throughout this leaflet.

Thoughts of suicide and worsening of your depression or anxiety
disorder:
If you are depressed and/or have anxiety disorders, you can
sometimes have thoughts of harming or killing yourself (see section 4
‘Possible side effects’). These may be increased when first starting
antidepressants, since these medicines all take time to work, usually
about two weeks but sometimes longer.

Read all of this leaflet carefully before you start taking this
medicine because it contains important information for you.
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or pharmacist.
This medicine has been prescribed for you. Do not pass it on to others.
It may harm them, even if their signs of illness are the same as yours.
If you get any side effects, talk to your doctor or pharmacist. This
includes any possible side effects not listed in this leaflet.




What is in this leaflet:
1. What Tranylcypromine 10mg Tablets are and what they are used for
2. What you need to know before you take Tranylcypromine 10mg
Tablets
3. How to take Tranylcypromine 10mg Tablets
4. Possible side effects
5. How to store Tranylcypromine 10mg Tablets
6. Contents of the pack and other information

You may be more likely to think like this if you:
have previously had thoughts about killing or harming yourself.
are a young adult. Information from clinical trials has shown an
increased risk of suicidal behaviour in adults aged less than 25
years with psychiatric conditions who were treated with an
antidepressant.
If you have thoughts of harming or killing yourself, at any time, contact
your doctor or go to a hospital straight away. You may find it helpful to
tell a relative or close friend that you are depressed or have an anxiety
disorder, and ask them to read this leaflet. You might ask them to tell
you if they think your depression or anxiety is getting worse, or if they
are worried about changes in your behaviour.
Children and adolescents

1. WHAT TRANYLCYPROMINE 10MG TABLETS ARE AND WHAT
THEY ARE USED FOR

Tranylcypromine 10mg Tablets is not recommended for children under
18 years old (see section 3 ‘Use in children and adolescents’).

Tranylcypromine 10mg Tablets contain the active substance
tranylcypromine which belongs to a group of antidepressant medicines
known as monoamine oxidase inhibitors (MAOIs). It works by stopping
the breakdown of two substances in the brain called serotonin and
noradrenaline. Your medicine should help bring these substances back
to normal levels.
This medicine is used to treat moderate to severe depression in adults.
It can also help you if you are having feelings of fear (phobia) which
sometimes occurs in depression. This medicine is often used when
other types of antidepressant medicines have not worked.

Other medicines and Tranylcypromine 10mg Tablets
Please tell your doctor or pharmacist if you are taking, have recently
taken or might take any other medicines, including medicines obtained
without a prescription.
DO NOT take Tranylcypromine 10mg Tablets with the following
medicines:

Medicines called sympathomimetic agents - these include
ephedrine, pseudoephedrine, adrenaline and noradrenaline (these
may be found in medicines used to treat heart problems and
asthma as well as some decongestants and cough/cold remedies)

Bupropion, a medicine to help you stop smoking

medicines to control appetite, e.g. amphetamine and fenfluramine

medicines that treat Parkinson’s disease, e.g. levodopa

dopamine, a medicine used to treat certain heart conditions

the pain killers pethidine and nefopam

general anaesthetics such as propofol, which are used in surgery

other medicines used to treat depression (e.g. amitriptyline,
imipramine, tryptophan)

buspirone, used to treat anxiety.

2. WHAT YOU NEED TO KNOW BEFORE YOU TAKE
TRANYLCYPROMINE 10MG TABLETS
Do not take Tranylcypromine 10mg Tablets if:
You are allergic to tranylcypromine or any of the other ingredients
of this medicine (listed in section 6)

You are taking other MAOIs or have taken other MAOIs within the
last two weeks

You have taken clomipramine or imipramine within the last three
weeks or are planning to take them within the next three weeks

You suffer from porphyria (which is an inherited disease affecting
the nervous system and skin)

You have severe heart disease or any disease of the blood
vessels of the brain

You have pheochromocytoma which is a tumour of the adrenal
glands (glands near the kidneys) causing high blood pressure

You have been diagnosed with an overactive thyroid gland (a
gland in the neck)

You have known liver damage or a disorder affecting the blood
cells (your doctor will know)

You are taking any of the medicines listed under ‘Do not take’ in
the Other Medicines and Tranylcypromine 10mg Tablets section of
this leaflet.

Please tell your doctor if any of the above apply to you, and do not
take Tranylcypromine 10mg Tablets.


Tranylcypromine 10mg Tablets must be taken with caution if you
are taking the following medicines:
other MAOIs such as isocarboxazid
strong pain killers e.g. codeine
medicines to treat seizures/fits, e.g. carbamazepine
barbiturates used to treat severe sleeping problems, e.g.
amylobarbitone

SSRIs such as fluoxetine or sertraline (for depression). Taking
your medicine with these products may cause the following serious
side effects: sweating, extreme agitation, confusion, muscle
stiffness

medicines for high blood pressure (e.g. guanethidine, reserpine,
methyldopa)

medicines to treat diabetes (e.g. insulin, metformin)

antihistamines used to treat allergies, e.g. cetirizine.
Consult your doctor before you take Tranylcypromine if you are taking
or might be taking any of these.





Warnings and precautions
Talk to your doctor or pharmacist before taking this medicine if
you:






Revision Date: 16.08.2016
Leaflet Reference: TRAN10

Tranylcypromine 10mg Tablets with food, drink and alcohol
You should NOT take alcohol (especially red wine) whilst you are
taking Tranylcypromine 10mg Tablets. This includes non-alcoholic
beer or lager.
Tranylcypromine 10mg Tablets stops the breakdown of a substance
called tyramine which is found in large amounts of certain foods. If this
substance is not broken down, it can cause very high blood pressure.

are elderly
have a mild heart problem which restricts your activity
suffer from seizures/fits (epilepsy)
are due to have surgery in the next few weeks
have a history of dependence on drugs or alcohol.
Even though some of the above may be obvious, it is important that
your doctor is aware if any of them apply to you.

1

So, whilst you are taking Tranylcypromine 10mg Tablets, you should
avoid the following foods:

Matured cheeses (e.g. cheddar or processed cheese made from
mature cheese)

Yeast extracts (e.g. Bovril or Marmite)

Meat, fish or poultry which is not fresh or has been pickled

Broad bean pods

Banana skins.

When the time comes to stop your doctor will probably decrease your
dose gradually as stopping the tablets suddenly may cause ill-effects
such as nausea (feeling sick), vomiting (being sick), sweating and
difficulty in sleeping. If you have any further questions on the use of
this medicine, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Tranylcypromine 10mg Tablets can cause side
effects, although not everybody gets them.
If you eat foods or take medicines which interact with the active
ingredient tranylcypromine, you may get very high blood pressure (a
hypertensive crisis).
If you notice any of the following symptoms please see your doctor
immediately:

frequent or throbbing headaches, painful or stiff neck, changes in
heart rate, pain in the middle of the chest, feeling sick or being
sick, sweating, paleness, or flushing of the skin and enlarged
pupils which may make bright sunlight uncomfortable. Although
very rare, there may be muscle weakness or paralysis (loss of
movement) down one side of the body and there have been a few
deaths from hypertensive crisis.

thoughts of suicide and suicidal behaviour early on in treatment or
shortly after stopping treatment (see section 2 ‘Thoughts of suicide
and worsening of your depression or anxiety disorder’).

Pregnancy and breast feeding
If you are pregnant or breast-feeding, think you may be pregnant or
planning to have a baby, ask your doctor or pharmacist for advice
before taking this medicine.
Tranylcypromine 10mg Tablets should NOT be used during pregnancy
or breast feeding unless your doctor thinks it is essential. This
medicine may pass into breast milk.
Your doctor will decide whether you should ablactate (gradually
reduce) or stop therapy with Tranylcypromine 10mg Tablets. Effects of
Tranylcypromine on fertility are unknown.
Driving and using machines
Tranylcypromine 10mg Tablets may make you feel drowsy or dizzy or
affect your concentration. You should not drive or use machines when
you first start to take this medicine until you are certain that you are not
getting these side effects. If in any doubt, speak to your doctor before
you drive or use machines.
Important information about some of the ingredients of
Tranylcypromine 10mg Tablets

Sometimes patients feel anxious whilst taking this medicine and rarely
some patients will become very agitated or irritable. Your doctor may
reduce your dose if this happens.
Some patients get low blood pressure and may feel dizzy on standing
up. If this continues for a long time, your doctor may stop your
medicine.
Other side effects which may occur include:

difficulty in sleeping, mild headache, sleepiness, weakness,
dizziness, fast heart beat (palpitations), restlessness, dry mouth,
blurred vision, feeling sick, water retention or swelling, weight gain,
increased appetite, rash and difficulty in passing water.

This medicine also contains carmoisine (E122) and Ponceau 4R
(E124) which may cause allergic reactions.
This medicine also contains sucrose (a sugar). If you have been told
by your doctor that you have an intolerance to some sugars, contact
your doctor before taking this medicine.
3. HOW TO TAKE TRANYLCYPROMINE 10MG TABLETS
Always take this medicine exactly as your doctor has told you. Do NOT
take more than your doctor tells you to. Check with your doctor or
pharmacist if you are not sure.

6. CONTENTS OF THE PACK AND OTHER INFORMATION
What Tranylcypromine 10mg Tablets contain:
Each tablet contains tranylcypromine sulphate equivalent to 10mg of
tranylcypromine base.
Tranylcypromine 10mg Tablets also contain sucrose, maize starch,
calcium sulphate dihydrate (E516), carmellose sodium, magnesium
stearate (E470b). The coating contains gelatin, sucrose, docusate
sodium, purified talc (E553b), light kaolin (E559), calcium carbonate
(E170), ethylcellulose, acacia (E414), carmoisine (E122), ponceau 4R
(E124), maize starch, titanium dioxide (E171), carnauba wax (E903)
and edible ink [shellac, iron oxide black (E172), soya lecithin (E322)
and trace amounts of dimethyl siloxane].
What Tranylcypromine 10mg Tablets look like and contents of the
pack
Tranylcypromine 10mg tablets are bi-convex, geranium-red sugarcoated tablets marked with “FW 251” on one side. The tablets are in
white plastic containers with a cap and a security tag containing a
desiccant cartridge.
Tranylcypromine 10mg Tablets are available in containers of 28
tablets.
Who manufactured your medicine
Tranylcypromine 10mg tablets are manufactured by Dales
Pharmaceuticals Ltd., Snaygill Industrial Estate, Keighly Road,
Skipton, North Yorkshire, BD23 2RW, UK. Procured from within the EU
and repackaged by Product Licence Holder: Beachcourse Limited, 20
Alliance Court, Alliance Road, London W3 0RB.

PL
16378/0551
Revision date: 16.08.2016

POM

Leaflet reference: TRAN10

Rarely some patients experience soreness in the hands and feet,
which may be a sign of inflamed nerves.
Rarely, some patients may find the relief of their depression decreases
with time and higher doses of the active ingredient, tranylcypromine,
are needed to get the same effect.

Swallow the tablets whole with a glass of water.
The recommended dose for adults is:
One tablet in the morning and one tablet in the afternoon each day
Try to take the last dose before 3 o’clock in the afternoon
This dose may be increased by your doctor to three tablets a day.
Take the extra tablet at mid-day

If you are elderly your doctor will usually prescribe you a lower
dose.
When you start to feel better, your doctor may change your dose to
one tablet a day.
Do NOT take more than three tablets each day unless your doctor tells
you to.




Very rarely, liver problems (symptoms include yellowing of the skin and
the whites of the eyes), bruising and changes in blood have been
reported. Therefore, if you get a bad sore throat or high fever or
become very tired and pale or notice bruises and nose bleeds, tell your
doctor.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You can
also report side effects directly via the Yellow Card Scheme at:
www.mhra.gov.uk/yellowcard.
By reporting side effects, you can help provide more information on the
safety of this medicine.

Use in children and adolescents
Tranylcypromine 10mg Tablets are not recommended for children
under 18 years old (see section 2 ‘Children and adolescents’).
If you take more Tranylcypromine 10mg Tablets than you should:
If you think that you, or any other person, have taken too many tablets,
contact your doctor or hospital casualty department immediately. Take
any remaining tablets and this leaflet with you so that the medical staff
know exactly what you have taken.

5. HOW TO STORE TRANYLCYPROMINE 10MG TABLETS
Keep this medicine out of the sight and reach of children.
Do not use Tranylcypromine 10mg Tablets after the expiry date which
is stated on the carton and label after EXP. The expiry date refers to
the last day of that month.
If your tablets are out of date, take them to your pharmacist who will
get rid of them safely.
Do not store above 25°C Store in original container in order to protect
from light and moisture. Replace cap tightly after use.
Medicines should not be disposed via wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer required.
These measures will help to protect the environment.

If you forget to take your Tranylcypromine 10mg Tablets:
If you miss a dose, wait until your next dose. Do not take the dose you
have missed. You can then carry on as before. Do not take more than
one dose at a time.
If you stop taking Tranylcypromine 10mg Tablets
Continue to take Tranylcypromine 10mg Tablets even if you no longer
feel ill. DO NOT STOP taking this medicine without talking with your
doctor first, especially if you have taken large doses for a long time.

2

3

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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