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Active substance(s): ST JOHNS WORT DRY EXTRACT

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Patient Information Leaflet

Also sunburn-like reactions on
skin exposed to strong sunlight
or strong ultra-violet (UV)
irradiation e.g. solarium have
been reported, particularly in
fair skinned individuals. Other
side effects that have been
After taking this product:
You must speak to a doctor or reported include headaches,
qualified healthcare practitioner nerve pain or tingling, anxiety,
dizziness and mania.
if your symptoms worsen, if
they do not improve after six
If any of the above side
weeks, or if any of the side
effects become serious or
effects become serious or if
if you experience any side
you notice any side effects not effects not listed, consult your
mentioned in the leaflet.
doctor or qualified healthcare
If you forget to take
this product:
Continue to take your usual
dose at the usual time, it does
not matter if you have missed
a dose.

If you have any questions, or practitioner.
are unsure about anything,
5. How to store this product
please ask your doctor,
Do not store above 25°C.
pharmacist or qualified
Store in the original package
healthcare practitioner.
Keep the tablets out of the
4. Possible side effects
reach and sight of children.
Like all medicines, this product Keep your tablets in the
can have side effects.
blister pack until it is time
The following side effects have to take them.
been reported:
Do not use Thompson &
• Gastrointestinal disorders
Capper St John’s Wort tablets
such as indigestion, loss of
after the expiry date which is
appetite, nausea, diarrhoea
stated on the box and blister
and constipation.
pack. The expiry date refers
• Fatigue and restlessness.
to the last day of that month.
Return any out of date tablets
• Allergic skin reactions such
to your pharmacist who will
as rash, hives or itching of
dispose of them for you.
the skin. If you experience
allergic skin reactions, stop
taking the product and
consult your doctor.

6. Further information

Traditional registration holder
and manufacturer for this
product: Thompson & Capper
Ltd. Hardwick Road, Astmoor,
Runcorn, Cheshire. WA7 1PH.

Each film-coated tablet
contains 425mg of extract
(as dry extract) from St John’s
Wort aerial parts (Hypericum
perforatum L.) (5-7/1)
(equivalent to 2125mg–2975mg THR 01359/0005
of St John’s Wort). Extraction
You can help make medicines
solvent: Ethanol 60% V/V.
safer by reporting any side
This product also contains the effects to the Yellow Card
Scheme at
following ingredients:
Excipients in the extract:
Alternatively you can get a
Maltodextrin, silica colloidal
paper Yellow Card from your
GP’s surgery or call freephone
Tablet core: Maltodextrin,
0808 100 3352 (available 10am
microcrystalline cellulose,
- 2pm Monday - Friday).
croscarmellose sodium,
stearic acid, magnesium
If you would like further
stearate, silica colloidal
information about this product
or a version of this leaflet in
Tablet coating: Hypromellose, large print or audio format
iron oxide red (E172), titanium please contact:
dioxide (E171), glycerol.
The tablets are red coated
01928 573734
and oval shaped.
Email: Enquiries@
Each pack contains 30, 60
This leaflet was
or 90 coated tablets
revised in June 2011
Not all pack sizes may be

St John’s wort extract 425mg

Please read this information carefully before you start taking
these tablets. It contains some important information about
this product. Keep this leaflet with the tablets. You may want to
read it again or show it to your doctor, pharmacist or qualified
healthcare practitioner.
You must speak to a qualified healthcare practitioner if your
symptoms worsen, if they do not improve after six weeks,
or if side effects not mentioned in this leaflet occur.
What is in this leaflet
1. What this product is and what it is used for

page 1

2. Before you take this product

page 2

3. How to take this product

page 4

4. Possible side effects

page 5

5. How to store this product

page 5

6. Further information

page 6

1. What this product is and what it is used for
This product is a traditional herbal medicinal product containing
St John’s Wort extract.
Thompson & Capper St John’s Wort tablets are a traditional
herbal medicinal product used to relieve the symptoms of
slightly low mood and mild anxiety based on traditional
use only.

Certification Mark



2. Before you take this

While you are taking this
• avoid excessive sunbathing
2.1 Do not take this product if:
or the use of sunbeds/
• your skin is exceptionally
sensitive to sunlight
• stop using it at least 10 days
prior to undergoing any
• you are having light treatment surgery.
(phototherapy) for any
2.2 Driving and operating
• you are suffering from
In rare cases St John’s Wort
depression (see below)
may make you feel dizzy or
• you are pregnant or
sleepy. If affected do not drive
or use machines.
• you are allergic to any of the
2.3 Taking this product with
ingredients (see section 6)
other medicines
• Are under the age of
St John’s Wort can affect the
18 years.
way some medicines work
and reduce their effectiveness.
Suffering from depression?
Medicines that can be affected
Symptoms of depression
by St John’s Wort include
include feelings of helplessness
prescription medicines, and
and hopelessness, loss of
those that you may have
interest in daily activities,
bought without a prescription.
appetite or weight changes,
Therefore it is important that
changes in sleep pattern,
you do not take Thompson &
loss of energy and difficulty
Capper St John’s Wort if you
concentrating. If your doctor
are using any of the medicines
has told you that you are
suffering from depression
do not use this product. If
you think that you may be
suffering from depression you
should tell your doctor before
taking this product.


All hormonal contraceptives:
The birth control ‘Pill’,
emergency contraception,
hormonal implants, creams,
patches, intra-uterine devices
with hormones.

All medicines for HIV
infections: Amprenavir,
atazanavir, darunavir,
fosamprenavir, indinavir,
lopinavir, nelfinavir, ritonavir,
saquinavir, tipranavir, efavirenz,
All medicines for depression/ nevirapine, delavirdine.
anxiety: Amitriptyline,
Some medicines for
clomipramine, moclobemide,
cholesterol: Simvastatin,
citalopram, escitalopram,
fluoxetine, fluvoxamine,
Some medicines for cancer:
paroxetine, sertraline,
Irinotecan, dasatinib, erlotinib,
duloxetine, venlafaxine.
imatinib, sorafenib, sunitinib,
All hormonal replacement
therapy (HRT) treatments:
HRT tablets, patches, gels,
vaginal rings.

etoposide, mitotane.

All medicines for thinning
the blood (anticoagulants):
Warfarin, acenocoumarol.

Some medicines for
migraines: Almotriptan,
eletriptan, frovatriptan,
naratriptan, rizatriptan,
sumatriptan, zolmitriptan.

All medicines for
epilepsy: Carbamazepine,
phenobarbitone, phenytoin,
primidone, sodium valproate.
All immunosuppressant
medicines: Ciclosporin,

Some medicines for heart
disease: Digoxin, ivabradine,


2.3 Taking this product
with other medicines
Thompson & Capper St John’s
Wort may also affect the
following medicines. Therefore
do not take this product with
these medicines unless a
doctor has said it is safe
to do so:

• rasagiline (an antiParkinson’s medicine)
• aripiprazole (an
antipsychotic medicine)

A medicine for regulating
mood: Lithium.

• buspirone (an anxiolytic)

A thyroid hormone: Thyroxine.

• eplerenone (a diuretic)
• lansoprazole and
omeprazole (proton pump
• theophylline
(a bronchodilator)

• fentanyl, propofol,
• gliclazide (an antidiabetic
sevoflurane, and midazolam medicine).
3. How to take this product
• tramadol (an analgesic)
Adults and the elderly
• erythromycin,
Take 1 tablet daily. Swallow the
clarithromycin and
tablet whole with some water
telithromycin (antibiotics)
or other liquid. Do not chew
• itraconazole and
the tablet.
voriconazole (antifungals)
Do not exceed the stated dose.
• artemether and
lumefantrine (antimalarials)

Some medicines for high
blood pressure: Amlodipine,
nifedipine, felodipine,

• exemestane (a hormone

If you take too much of this
product (overdose):
If you take more than the
recommended dose, speak to a
doctor, pharmacist or qualified
healthcare practitioner and take
this leaflet with you.

• aprepitant (used to treat
post-operative vomiting)
• butobarbital and
phenobarbital (barbiturates)
• methyl phenidate (a central
nervous system or CNS



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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.