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Active substance(s): ASPIRIN / ASPIRIN / ASPIRIN

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Package leaflet: Information for the user
Aspirin 300mg Tablets
Read all of this leaflet carefully before you start taking this medicine because it contains
important information for you.
Always take this medicine exactly as described in this leaflet or as your doctor, pharmacist or
nurse have told you.
- Keep this leaflet. You may need to read it again.
- Ask your pharmacist if you need more information or advice
- If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any
possible side effects not listed in this leaflet. See section 4.
- You must talk to a doctor if you do not feel better or if you feel worse after 3 days.
The name of your medicine is Aspirin 300mg Tablets. In the rest of this leaflet, it is called
Aspirin Tablets.
What is in this leaflet
1. What Aspirin Tablets are and what they are used for
2. What you need to know before you take Aspirin Tablets
3. How to take Aspirin Tablets
4. Possible side effects
5. How to store Aspirin Tablets
6. Contents of the pack and other information
1. What Aspirin 300mg Tablets are and they are used for

What this medicine does
The active substance in your medicine is Aspirin. Aspirin belongs to a group of medicines
called non-steroidal anti-inflammatory drugs (NSAIDs). Aspirin works by preventing the
release in the body of substances which cause pain, inflammation and fever.
Aspirin Tablets are used:
 For the symptomatic relief of mild to moderate pain, including migraine, toothache,
neuralgia, headache, sore throat, period pains, aches and pains (including muscle
pains and backache).
 For the symptomatic relief of influenza, feverishness and feverish colds. For the
symptomatic relief of sprains, strains, rheumatic pain, sciatica, lumbago, fibrositis,
joint swelling and stiffness.

2. What you need to know before you take Aspirin Tablets

Aspirin can cause Reye’s syndrome when it is given to children. This is a very rare
disease but it can be fatal. Do not give aspirin to children under 16 years of age unless
your doctor tells you to.
Do not take Aspirin Tablets if you:

• are allergic to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) e.g.
ibuprofen, or any of the other ingredients of this medicine (listed in section 6). Symptoms
may include rhinitis (runny nose), swollen face, mouth or tongue, itchy rash or asthma attack;
• have or have had a stomach ulcer;
• have a condition where your blood does not clot properly (e.g. haemophilia);
• are taking medicines to thin your blood such as warfarin;
• have or have had gout;
• are in the last 3 months of pregnancy or are breast-feeding.
Warnings and Precautions
Talk to your doctor, pharmacist or nurse before taking Aspirin Tablets if you:
• have asthma, or suffer from allergies
• have problems with your heart, kidneys or liver
• are dehydrated
• have nasal polyps (inflamed swellings inside the nose)
• suffer from indigestion (dyspepsia)
• have an infection
• have high blood pressure
• have a lack of glucose 6-phosphate dehydrogenase (G6PD)
• are elderly
• are diabetic
You should let your doctor know you are taking aspirin tablets, particularly if you are going
to have an operation, as you may need to stop taking your tablets several days before the
Your blood, kidney and liver should be monitored during prolonged use of aspirin as blood,
kidney and liver disorders may develop.
Other Medicines and Aspirin Tablets
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other
medicines. The following medicines can affect or be affected by Aspirin:
• Alcohol: some of the effects of aspirin are enhanced.
• Mifepristone (used to terminate pregnancy). You should not take aspirin until eight to
twelve days after mifepristone. If taken with aspirin this medicine may not be as effective.
• Non-steroidal anti-inflammatory (NSAIDs) e.g. ibuprofen or diclofenac sodium (used for
pain relief and to treat inflammation) or Corticosteroids e.g. prednisolone and
betamethasone (used to treat allergy or inflammation): if taken with aspirin you may have
more severe side effects e.g. increased risk of bleeding or ulcers in the stomach. If you
suddenly stop taking corticosteroids you may develop aspirin poisoning.
• Metoclopramide (used to treat nausea and vomiting): it may increase the effect of aspirin.
• Adsorbents e.g. kaolin (for diarrhoea) and Antacids e.g. aluminium hydroxide and
magnesium carbonate (used to treat indigestion): these medicines may reduce the effect of
• Medicines known to affect the clotting of your blood: if you take one of these medicines
below with aspirin you may increase the likelihood of bleeding.
• Coumarins e.g. warfarin, phenindone or heparins (blood thinning medicines), streptokinase.
• Clopidogrel and ticlopidine (used to prevent strokes and heart attacks).
• Calcium channel blockers such as verapamil, used to treat high blood pressure.

• ACE Inhibitors or Angiotensin-II Receptor Antagonists e.g. captopril, enalapril maleate,
valsartan, losartan (used to lower high blood pressure): taken with aspirin these medicines
may not be as effective and you may suffer from kidney problems.
• Antidepressants (used to treat depression) e.g. Selective Serotonin Re-uptake Inhibitors
(SSRIs) (such as venlafaxine): if taken with aspirin you may increase the likelihood of
• Medicines to control epilepsy e.g. phenytoin and valproate: aspirin may increase the effect
of these medicines. If you take sodium valproate with aspirin you may increase the likelihood
of bleeding
• Zafirlukast (used to prevent or treat asthma).
• Spironolactone (diuretic) water tablets, Probenicid or Sulfinpyrazone (used to treat gout):
if taken with aspirin these medicines may not be as effective. Phenylbutazone may reduce the
effect of aspirin.
• Methotrexate (used in the treatment of arthritis, Crohn’s disease and cancer) or Carbonic
anhydrase inhibitors e.g. acetazolamide (used in the treatment of glaucoma, epilepsy and
excess water retention): if taken with aspirin the side effects of these medicines may become
more severe.
• Steroids such as cortisone and hydrocortisone, used to treat allergic conditions.
• Thiopental (used as an anaesthetic).
• Gold compounds (used to treat rheumatoid arthritis).
• Insulin and other drugs used to treat diabetes.
• Sulphonamides, such as sulphamethoxazole, used to treat infections.
• Vitamin C.
• Cilostazol (for leg pain that occurs when walking due to poor circulation): the dose of
aspirin should not be greater than 80mg a day.
Aspirin may affect the results of thyroid function tests.
Aspirin Tablets with alcohol
Avoid drinking alcohol while taking Aspirin.
Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a
baby, ask your doctor or pharmacist for advice before taking this medicine.
Taking this medicine may impair the fertility in women. This effect is reversible on stopping
the medicine.
Aspirin Tablets contain lactose.
If you have been told by your doctor that you have an intolerance to some sugars, contact
your doctor before taking this medicinal product, as it contains lactose.
3. How to take Aspirin Tablets

For oral use.
Always take this medicine exactly as described in this leaflet or as your doctor, pharmacist or
nurse have told you. Check with your doctor, pharmacist or nurse if you are not sure.
Adults (including the elderly and children over 16 years):
The recommended dose is one to three tablets, swallowed whole with water.

The dose should not be taken more frequently than every four hours and not more than four
times in any 24 hour period.
Maximum daily dose: 12 tablets (3.6g) every 24 hours in divided doses.
Take the tablets with or immediately after food to reduce the risk of getting stomach and
bowel irritation.
Do not take more medicine than the label tells you to.
If you do not get better, talk to your doctor.
Children and Adolescents
Do not give to children under 16 years of age unless your doctor tells you to.
If you take more Aspirin Tablets than you should
If you take more Aspirin Tablets than your doctor has prescribed contact your nearest
hospital casualty department or doctor immediately. Take the medicine or this leaflet with
you to show the doctor.
Symptoms of an overdose include vomiting, dehydration, tinnitus, vertigo, headache, nausea,
dizziness, restlessness, heart failure, breathing failure, deafness, sweating, warm extremities
with racing pulse, increased breathing rate and hyperventilation.
If you forget to take Aspirin Tablets
• If you forget to take a dose, do not worry. Take the next dose when it is due.
• Do not take a double dose to make up for a forgotten dose.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or
4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
If you experience the following side effects while taking your medicine, you should stop
taking your tablets and tell your doctor straight away:
• allergic reaction (hypersensitivity) which may include lumpy skin or hives, skin rash,
swelling of eyelids, face, lips, mouth or tongue, or sudden wheeziness, or induce or worsen
asthma attacks;
• you suffer from severe or persistent indigestion, stomach upset or pain, you may develop
ulcers or bleeding from the stomach which can cause severe stomach pain, bloody or black
tarry stools or vomiting blood.
Other possible side effects:
• stomach upset and feeling sick;
• an increased tendency to bleed;
• anaemia and other blood disorders;
• mouth ulcers;
• slight blood loss which may result in iron-deficiency anaemia during long term use;
• diarrhoea;

• blood in the urine;
• Stevens-Johnson syndrome (fever, rash, sore mouth and eyes, joint and muscle aches);
• severe skin problem with shedding of upper layer;
• you may succumb to infections more easily;
• you may bruise more easily.
Some patients have developed liver problems (particularly with high doses).
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any
possible side effects not listed in this leaflet. You can also report side effects directly via the
yellow card scheme at
By reporting side effects you can help provide more information on the safety of this
5. How to store Aspirin Tablets
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the label.
Do not store above 25°C. Store in the original container.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist
how to throw away medicines you no longer use. These measures will help protect the
6. Contents of the pack and other information

What Aspirin Tablets contain
The active substance is aspirin. Each tablet contains 300mg of aspirin.
The other ingredients are lactose, starch and talc.
What Aspirin Tablets look like and contents of the pack
Aspirin Tablets are white, round tablets, which have embossed on one face and a break
line on the other.
Each pack of Aspirin Tablets contains 8, 10, 12, 16, 20, 24, 25, 28, 30, or 32 tablets. Packs of
20, 24, 25, 28, 30 and 32 tablets are only available from your pharmacist. Packs of 48, 50, 96
and 100 tablets are only available on prescription from your doctor. Packs of 250, 500, 1000
and 5000 are dispensary packs only. Not all pack sizes are marketed.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Wockhardt UK Ltd, Ash Road North, Wrexham, LL13 9UF, UK
CP Pharmaceuticals Ltd, Ash Road North, Wrexham, LL13 9UF, UK.
Other formats:
To listen to or request a copy of this leaflet in Braille, large print or audio please call, free of
charge: 0800 198 5000 (UK Only)

Please be ready to give the following information:
Product name

Reference number

Aspirin 300mg Tablets


This leaflet was last revised in 05/2017.

Expand Transcript

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.