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alpha blockers used to treat high blood pressure and heart
conditions (these include prazosin and terazosin)

diuretics (also called ‘water pills’)

Your medicine is known as Securon SR Tablets 240mg but will be
referred to as Securon SR Tablets or Securon SR throughout the
following leaflet.

medicines known as “statins” such as atorvastatin, lovastatin,
simvastatin used to lower cholesterol levels

any other medicine for high blood pressure or an abnormal
heart beat (arrhythmia) such as quinidine, flecainide,
disopyramide, digoxin and digitoxin


dabigatran (medicine to prevent the formation of blood clots)

Read all of this leaflet carefully before you start taking this

medicines containing ivabradine for the treatment of certain
heart diseases

medicines used to treat depression (including the herbal
product St John’s Wort), anxiety or psychosis. These may
include imipramine, buspirone and lithium

medicines known as immunosuppressants such as ciclosporin,
sirolimus, everolimus and tacrolimus. These are used to
prevent organ transplant rejection

S1590 LEAFLET Securon 20170616


(verapamil hydrochloride)

Keep this leaflet as you may need to read it again

This leaflet provides a summary of the information currently
available about Securon SR

For further information or advice ask your doctor or pharmacist

This medicine is for you only and should never be given to
anyone else, even if they appear to have the same symptoms
as you

glibenclamide, used to treat certain types of diabetes

Tell your doctor or pharmacist if you experience any side effects

aspirin, a non-steroidal anti-inflammatory painkiller (NSAID)
used to relieve pain and reduce fever

almotriptan, used to treat migraine

What is in this leaflet
1. What Securon SR is and what is it used for

midazolam, used as a sedative or anaesthetic

2. What you need to know before you take Securon SR

theophylline, used to treat asthma

3. How to take Securon SR

doxorubicin, an anti-cancer medicine

4. Possible side effects

cimetidine, used to treat indigestion or stomach ulcers

5. How to store Securon SR

rifampicin, used to treat tuberculosis and other types of infection

6. Contents of the pack and other information

carbamazepine, phenytoin or phenobarbital (phenobarbitone).
These medicines are used as anti-convulsants.

Securon SR tablets belong to a group of medicines called calcium
channel blockers. Calcium channel blockers change the amount of
calcium getting into the muscle cells in your heart and blood
vessels. This can change the strength and speed with which your
heart beats. It also opens up the blood vessels so blood can be
pumped around the body more easily. This helps more oxygen to
get to your heart muscle and can lower your blood pressure.
Securon SR tablets are used to treat hypertension (high blood
pressure) and to prevent angina (chest pain) attacks. The tablets
may also be prescribed following a heart attack, to prevent another
attack occuring.

ritonavir, used to treat HIV

erythromycin, clarithromycin and telithromycin, used to treat
certain types of infection

colchicine or sulfinpyrazone, used to treat gout.

Tell your surgeon or dentist that you are taking Securon SR if
surgery is planned as it may affect the anaesthetic used.
Driving and operating machines
Do NOT drive, operate machinery or do anything that requires you
to be alert, until you know how the tablets affect you.

The active ingredient in Securon SR tablets is verapamil

Securon SR can make some people feel dizzy, especially when
they first start to take the tablets.


Other important information

If the answer to any of the following questions is ‘YES’ please
tell your doctor or pharmacist BEFORE taking any tablets:

Are you sensitive (allergic) to verapamil or any of the other
ingredients in the tablets? (See section 6)

Are you pregnant or planning to become pregnant, or are you
breast feeding?

Do you have very low blood pressure?

Do you have or have you ever suffered from heart problems
such as heart failure?

Do you have an abnormally slow or irregular heart beat?

Have you recently had a heart attack?

Do you have liver or kidney problems?

Do you have or have you ever suffered from heart problems
such as heart failure or the heart condition called WolffParkinson-White syndrome?

Do you have a condition where the nerve to muscle
transmission is affected e.g. myasthemia gravis, Lambert-Eaton
syndrome, advanced Duchenne muscular dystrophy?

Are you being treated with ivabradine (for heart conditions)?

Taking other medicines.
Please tell your doctor or pharmacist if you are taking any
medicines with or without a prescription or have recently taken
any of the following medicines:

beta-blockers used to treat high blood pressure and heart
conditions (these include atenolol, propranolol and metoprolol)

Do NOT drink grapefruit juice whilst taking your tablets as it can
affect the absorption of this medicine. This does not occur with
other fruit juices such as orange, apple or tomato juice.
Drinking alcohol
Securon SR will increase the time your body takes to get rid of
alcohol. This means that you may not have to drink as much for
your blood alcohol levels to be above the legal limit to drive. It will
also take you longer to sober up.
Taking Securon SR with food and drink
Your tablets can be taken with a glass of water to help you swallow
them. It does not matter if you have eaten, so they can be taken
with or without food.
Pregnancy and breast feeding
Please discuss with your doctor if you are pregnant, planning to
become pregnant or are breast feeding.
ALWAYS take this medicine exactly as your doctor has told you.
Check with your doctor if you are not sure.
TAKE YOUR TABLETS with a glass of water. You should swallow
the tablets without chewing or crushing them. It does not matter if
you have not eaten.
The number of tablets that you will need to take will depend on what
you are being treated for:

Hypertension (high blood pressure)
The recommended dose is one Securon SR 240 mg tablet a day. If
you have not taken Securon SR 240 mg before, your doctor may
prescribe a lower dose such as a Half Securon SR 120 mg tablet
each day. The maximum dose to treat high blood pressure is 480
mg each day. This is usually taken as one Securon 240 mg tablet in
the morning and one in the evening, leaving a gap of about 12
hours between each dose.
Angina (chest pain)
The usual starting dose for angina is one Securon SR 240 mg tablet
taken twice a day. You should take one tablet in the morning and
one in the evening, with a gap of about 12 hours in between them.
Your doctor may prescribe a lower dose according to your

Other side effects might occur if Securon SR is used for a long time.
Tell your doctor if you develop swollen gums which start to spread
over your teeth, or if your breasts swell (males) or start to produce
milk (males and females). These effects are rare and are resolved
upon stopping taking the tablets.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You
can also report side effects directly via the Yellow Card Scheme at:
By reporting side effects, you can help provide more information on
the safety of this medicine.

Keep out of the sight and reach of children.

Following a heart attack

Do not store your tablets above 25°C.

The usual dose following a heart attack is 360 mg each day. This
may be taken as one Securon SR 240 mg tablet in the morning and
a Half Securon SR 120 mg tablet in the evening or as one Half
Securon SR 120 mg tablet taken three times a day. The doctor will
usually wait at least a week after your heart attack before
prescribing these tablets.

Store in original package.

Do not use Securon SR after the expiry date which is stated on
the carton and blister strip. The expiry date refers to the last day
of that month.

If your doctor tells you to stop using the medicine, please take it
back to the pharmacist for safe disposal. Only keep the
medicine if your doctor tells you to.

If the medicine becomes discoloured or shows any other signs
of deterioration, you should seek the advice of your pharmacist
who will tell you what to do.

Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help to
protect the environment.

Securon SR is NOT recommended for children under 12 years of
The dose will be the same as that for adults. If you have kidney or
liver problem, your doctor may lower your dose.
If you take more Securon SR than you should
If you take more tablets than prescribed (an overdose) you should
contact a doctor or go to the nearest hospital casualty department
IMMEDIATELY taking your tablets with you.
If you forget to take Securon SR
If you forget to take your tablets take them as soon as you
remember, unless it is almost time for your next dose. If it is, do not
take the missed dose at all. Do not take double dose to make up for
a forgotten tablet.
If you stop taking Securon SR
If you stop taking your tablets your condition may get worse. It is
important that you keep taking these tablets until your doctor tells
you to stop. Do NOT stop just because you feel better.

What Securon SR contains

Each tablet contains 240mg of verapamil hydrochloride in a
modified release formulation.

The other ingredients are: microcrystalline cellulose, sodium
alginate, povidone, magnesium stearate, purified water and a
tablet coating: hypromellose, macrogol 400, macrogol 6000,
talc, titanium dioxide (E171), quinoline yellow (E104), indigo
carmine (E 132) and glycol wax.

Other things to remember about Securon SR

What Securon SR looks like and contents of the pack

Securon SR 240 mg tablets may be broken in half if your doctor
advises you to do so (e.g. if a lower dose has been prescribed).

Securon SR Tablets are oblong, pale, green, scored and embossed
with two Knoll logos (triangles) on one side.

The tablets should NOT be crushed, chewed or sucked, as this
will affect the modified-release formulation of the product.

Securon SR is available as blister packs of 20 and 30 tablets.

Product Licence holder

If you have any further questions on the use of this medicine, ask
your doctor or pharmacist.

Procured from within the EU and repackaged by the Product
Licence holder: S&M Medical Ltd, Chemilines House,
Alperton Lane, Wembley, HA0 1DX.



As with all medicines, Securon SR can cause side effects, although
not everyone will suffer from them. If you experience any other
unusual symptoms whilst taking your tablets, tell your doctor
or pharmacist.

This product is manufactured by

Tell your doctor IMMEDIATELY if you experience any of the
following side effects:

Yellowing of the skin or eyes, a fever or tenderness around the
middle. These are signs that your liver may not be functioning
as well as usual

Palpitations, chest pains for the first time or chest pains
becoming more frequent, swollen ankles, hot and painful hands
or feet

Swelling of the limbs

Unexpected wheezing, difficulty breathing, swelling of the
mouth, lips or tongue or severe skin rash

The most common side effect is constipation. Other side effects
include abnormal heart beat, flushing of the face or neck,
headaches, feeling or being sick, abdominal pain or discomfort,
dizziness, vertigo, tinnitus (ringing or buzzing in the ears), tiredness,
tremor, movement disorders, muscle weakness, aches and pains in
the joints and/or muscles, skin rash or itching, a tingling or prickling
feeling on the skin, numbness and hair loss. Impotence may occur

• AbbVie Deutschland GmbH & Co. KG, Knollstrasse, 67061
Ludwigshafen, Germany.
• FAMAR A.V.E Anthoussa plant, Anthoussa Attiki, 15344,

PL: 19488/1590

Leaflet revision date: 16 June 2017

Blind or partially sighted? Is
this leaflet hard to see or read?
Call 02087997607 to obtain the
leaflet in large print, tape, CD
or Braille.
Securon is a registered trade mark of Mylan Healthcare GmbH.
S1590 LEAFLET Securon 20170616

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.