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Securon® SR
240 mg Tablets
(verapamil hydrochloride)
This product is available as the above name but
will be referred as Securon SR throughout the
following leaflet. Please note this leaflet also
contains information about Half Securon® SR
120 mg modified release tablets.

Read all of this leaflet carefully
before you start taking this
• Keep this leaflet as you may
need to read it again
• For further information or
advice ask your doctor or
• This medicine is for you only
and should never be given to
anyone else, even if they
appear to have the same
symptoms as you
• Tell your doctor or pharmacist if
you experience any side effects

Leaflet contents:
1. What is Securon SR and what is it used for?
2. What should you know before taking your tablets?
3. How should you take your tablets?
4. Possible side effects.
5. How should you store your tablets?
6. Further information.

1. What is Securon SR and what is it used
Securon SR tablets belong to a group of medicines
called calcium channel blockers. Calcium channel
blockers change the amount of calcium getting into
the muscle cells in your heart and blood vessels.
This can change the strength and speed with which
your heart beats. It also opens up the blood vessels
so blood can be pumped around the body more
easily. This helps more oxygen to get to your heart
muscle and can lower your blood pressure.
Securon SR tablets are used to treat hypertension
(high blood pressure) and to prevent angina (chest
pain) attacks. The tablets may also be prescribed
following a heart attack, to prevent another attack
The active ingredient in Securon SR tablets is
verapamil hydrochloride.

2. What should you know before taking
your tablets?
If the answer to any of the following questions is
‘YES’ please tell your doctor or pharmacist
BEFORE taking any tablets:
• Are you sensitive (allergic) to verapamil or any of
the ingredients in the tablets? (See Section 6).
• Are you pregnant or planning to become pregnant,
or are you breast feeding?
• Do you have very low blood pressure?
• Do you have or have you ever suffered from heart
problems such as heart failure?

• Do you have an abnormally slow or irregular heart
• Have you recently had a heart attack?
• Do you have liver or kidney problems?
• Do you have or have you ever suffered from heart
problems such as heart failure or the heart
condition called Wolff-Parkinson-White syndrome?
• Do you have a condition where the nerve to
muscle transmission is affected e.g. myasthemia
gravis, Lambert-Eaton syndrome, advanced
Duchenne muscular dystrophy?
• Are you being treated with ivabradine (for heart
Taking other medicines.
Please tell your doctor or pharmacist if you are
taking any medicines with or without a
prescription or have recently taken any of the
following medicines:
• beta-blockers used to treat high blood pressure
and heart conditions (these include atenolol,
propranolol and metoprolol)
• alpha blockers used to treat high blood pressure
and heart conditions (these include prazosin and
• diuretics (also called “water pills”)
• medicines known as “statins” such as atorvastatin,
lovastatin, simvastatin used to lower cholesterol levels
• any other medicine for high blood pressure or an
abnormal heart beat (arrhythmia) such as
quinidine, flecainide, digoxin and digitoxin
• dabigatran, used to thin blood
• medicines containing ivabradine for the treatment
of certain heart diseases
• medicines used to treat depression (including the
herbal product St John’s Wort), anxiety or
psychosis. These may include imipramine,
buspirone and lithium.
• medicines known as immunosuppressants such as
ciclosporin, sirolimus, everolimus and tacrolimus.
These are used to prevent organ transplant rejection.
• glibenclamide, used to treat certain types of
• aspirin, a non-steroidal anti-inflammatory painkiller
(NSAID) used to relieve pain and reduce fever

almotriptan, used to treat migraine
midazolam, used as a sedative or anaesthetic
theophylline, used to treat asthma
doxorubicin, an anti-cancer medicine
cimetidine, used to treat indigestion or stomach ulcers
carbamazepine, phenytoin or phenobarbital
(phenobarbitone). These medicines are used as
rifampicin, used to treat tuberculosis and other
types of infection
ritonavir, used to treat HIV
erythromycin, clarithromycin and telithromycin, used
to treat certain types of infection
colchicine or sulfinpyrazone, used to treat gout.

Tell your surgeon or dentist that you are taking
Securon SR if surgery is planned as it may affect the
anaesthetic used.
Driving and operating machines
Do NOT drive, operate machinery or do anything that
requires you to be alert, until you know how the
tablets affect you.
Securon SR can make some people feel dizzy,
especially when they first start to take the tablets.
Other important information
Do NOT drink grapefruit juice whilst taking your
tablets as it can affect the absorption of this
medicine. This does not occur with other fruit juices
such as orange, apple or tomato juice.
Drinking alcohol
Securon SR will increase the time your body takes to
get rid of alcohol. This means that you may not have
to drink as much for your blood alcohol levels to be
above the legal limit to drive. It will also take you
longer to sober up.
Taking Securon SR with food and drink
Your tablets can be taken with a glass of water to
help you swallow them. It does not matter if you have
eaten, so they can be taken with or without food.
Pregnancy and breast feeding
Please discuss with your doctor if you are pregnant,
planning to become pregnant or are breast feeding.

3. How should you take your tablets?
ALWAYS take your tablets exactly as your doctor
has told you. If you are not sure refer to the label on
the carton or check with your doctor or pharmacist.
TAKE YOUR TABLETS with a glass of water. You
should swallow the tablets without chewing or
crushing them. It does not matter if you have not
The number of tablets that you will need to take will
depend on what you are being treated for:
Hypertension (high blood pressure)
The usual dose is one Securon SR 240 mg tablet a
day. If you have not taken Securon SR 240 mg
before, your doctor may prescribe a lower dose such
as a Half Securon SR 120 mg tablet each day. The
maximum dose to treat high blood pressure is 480
mg each day. This is usually taken as one Securon
SR 240 mg tablet in the morning and one in the
evening, leaving a gap of about 12 hours between
each dose.
Angina (chest pain)
The usual starting dose for angina is one Securon
SR 240 mg tablet taken twice a day. You should take
one tablet in the morning and one in the evening,
with a gap of about 12 hours in between them. Your
doctor may prescribe a lower dose according to your
Following a heart attack
The usual dose following a heart attack is 360 mg
each day. This may be taken as one Securon SR
240 mg tablet in the morning and a Half Securon SR
120 mg tablet in the evening or as one Half Securon
SR 120 mg tablet taken three times a day. The
doctor will usually wait at least a week after your
heart attack before prescribing these tablets.
Securon SR and Half Securon SR are NOT
recommended for children under 12 years of age.

If you take more tablets than prescribed (an
overdose) you should contact a doctor or go to the
nearest hospital casualty department IMMEDIATELY
taking your tablets with you.
If you forget to take your tablets take them as
soon as you remember, unless it is almost time for
your next dose. If it is, do not take the missed dose at
all. Never double up on a dose to make up for the
one you have missed.
If you stop taking your tablets your condition may
get worse. It is important that you keep taking these
tablets until your doctor tells you to stop. Do NOT
stop just because you feel better.
Other things to remember about Securon SR
• Securon SR 240 mg tablets may be broken in half
if your doctor advises you to do so (e.g. if a lower
dose has been prescribed).
• The tablets should NOT be crushed or chewed, as
this will affect the modified-release formulation of
the product.

4. Possible side effects
As with all medicines, Securon SR and Half Securon
SR can cause side effects, although not everyone
will suffer from them. If you experience any other
unusual symptoms whilst taking your tablets, tell
your doctor or pharmacist.
Tell your doctor IMMEDIATELY if you experience
any of the following side effects:
• Yellowing of the skin or eyes, a fever or
tenderness around the middle. These are signs
that your liver may not be functioning as well as
• Palpitations, chest pains for the first time or chest
pains becoming more frequent, swollen ankles, hot
and painful hands or feet
• Swelling of the limbs
• Unexpected wheezing, difficulty breathing, swelling
of the mouth, lips or tongue or severe skin rash

The most common side effect is constipation. Other
side effects include abnormal heart beat, flushing of
the face or neck, headaches, feeling or being sick,
abdominal pain or discomfort, dizziness, vertigo,
tinnitus (ringing or buzzing in the ears), tiredness,
tremor, movement disorders, muscle weakness,
aches and pains in the joints and/or muscles, skin
rash or itching, a tingling or prickling feeling on the
skin, numbness and hair loss. Impotence may occur
Other side effects might occur if Securon SR or Half
Securon SR are used for a long time. Tell your
doctor if you develop swollen gums which start to
spread over your teeth, or if your breasts swell
(males) or start to produce milk (males and females).
These effects are rare and are resolved upon
stopping taking the tablets.
Reporting of side effects
If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report
side effects directly via the Yellow Card Scheme at: By reporting side
effects you can help provide more information on the
safety of this medicine.

5. How should you store your tablets?

• If your medicine become discoloured or show
signs of any deterioration, consult your doctor or
pharmacist who will tell you what to do.

6. Further information
What Securon SR contains
Securon SR contains the active ingredient verapamil
hydrochloride, in a sustained release (slow release)
Each tablet contains 240 mg of verapamil
Inactive tablet ingredients:
Core ingredients: microcrystalline cellulose, sodium
alginate, povidone, magnesium stearate and purified
Coating ingredients: hypromellose, macrogol 400,
macrogol 6000, talc, titanium dioxide (E171),
quinoline yellow lake (E104), indigo carmine (E132)
and glycol wax.
Securon SR looks like:
Securon SR is an oblong, pale green, modified
released tablet, scored on both side and embossed
with the Knoll logos (triangles) on one side.
The tablets are available in blister packs of 20 or 30
PL: 15814/1199

• Do not store above 25°C. Store in the original
• Your tablets should be stored in a safe place out of
the sight and reach of children, your medicine
could harm them.
• Do NOT take your tablets after the expiry date
(EXP) date shown on the carton. The expiry date
refers to the last day of that month.
• If your doctor decides to stop your treatment,
return any leftover tablets to your pharmacist. Only
keep the tablets if your doctor tells you to. Do NOT
dispose of leftover tablets carelessly (e.g. down
the toilet or in with your general rubbish).


Manufactured by AbbVie Deutschland GmbH & Co.
KG, Ludwigshafen, Germany.
Procured from within the EU and repackaged by the
Product Licence holder: O.P.D. Laboratories Ltd.,
Unit 6 Colonial Way, Watford, Herts WD24 4PR.
Leaflet revision and issue date (Ref.): 16.02.2016.
Securon is a trademark of Abbott GmbH & Co. KG,
To request a copy of this leaflet in Braille, large print
or audio please call 01923 332 796.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.