Skip to Content

UK Edition. Click here for US version.

RELENZA 5MG INHALATION POWDER

Active substance(s): ZANAMIVIR

View full screen / Print PDF » Download PDF ⇩
Transcript
FRONT PAGE

PHARMA CODE

1
10000000114909

In this leaflet:
1

GSK-FRA-Evreux-FREVR
United Kingdom-GBR

Package Leaflet:
Information for the User

Relenza
1
5 mg per dose, inhalation powder,
pre-dispensed
zanamivir

K

What Relenza is and
what it is used for

2

Before you use Relenza

3

How to use Relenza

4

Possible side effects

5

How to store Relenza

6

Further information

1 What Relenza is and what
it is used for

Relenza contains zanamivir, which belongs to a
group of medicines called antivirals.

02_003_04

Read all of this leaflet carefully before you
start using this medicine.
Keep this leaflet. You may need to read it
again.
If you have any questions, ask your doctor
or pharmacist.
This medicine has been prescribed for you.
Don’t pass it on to others. It may harm
them, even if their symptoms are the same
as yours.
If you have serious side effects, or if you
notice any side effects not listed in this
leaflet, tell your doctor or pharmacist.

Relenza is used to treat flu (influenza virus
infection). It reduces the symptoms of flu, and
helps you recover more quickly.
Relenza is also used to help prevent you from
getting flu, during a flu outbreak.
Adults and children aged 5 years or more can be
treated with Relenza.
Relenza needs to be inhaled (breathed in) into
the lungs, because it is poorly absorbed into the
body if it is swallowed. The flu virus infects the
lungs, and when you inhale Relenza it works
directly on the virus inside your lungs.
Relenza is not a substitute for flu vaccination.
You still need to talk to your doctor about
whether you need to be vaccinated against flu.

Using Relenza with inhaled
medication for breathing problems

2 Before you use Relenza

If you use inhaled medication for asthma or any
other breathing problem, carry on using your
inhaler(s) at the usual times.
• If you have been advised to use Relenza at
the same time of day as your other inhaled
medication, use the other medication a few
minutes before you use Relenza.
• Make sure you have your fast-acting ‘reliever’
inhaler (such as salbutamol) to hand when you
use Relenza.
In very rare cases, Relenza can cause a reaction
including:
• tightness of the throat and chest
• difficulty breathing.
If you get any of these symptoms when you use
Relenza:

Don’t use Relenza:

• if you’re allergic (hypersensitive) to zanamivir
• if you’re allergic (hypersensitive) to lactose or
milk protein.

Take special care with Relenza
If you feel tightness in your throat or chest
when you use Relenza
In very rare cases, Relenza can cause a reaction
including:
• tightness of the throat and chest
• difficulty breathing.
If you get any of these symptoms when you use
Relenza:

➔ Stop using Relenza and get medical help

➔ Stop using Relenza. Use your fast-acting

immediately. Contact your doctor or the
nearest hospital emergency department.
Don’t give Relenza to children under 5 years old.

‘reliever’ inhaler to help your breathing.
Get medical help immediately. Contact
your doctor or the nearest hospital emergency
department.

If you have asthma, or other problems with
your lungs or your breathing

Using other medicines

Your doctor needs to know if you have:
• asthma
• other lung disease that causes breathing
problems — for example, emphysema,
chronic obstructive pulmonary disease (COPD),
or chronic bronchitis.

Please tell your doctor or pharmacist if you
are taking or have recently taken any other
medicines, including medicines obtained without
a prescription.
If you use inhaled medication for asthma or other
breathing problems, make sure you have read the
advice above.

➔ Tell your doctor before you use Relenza,

so that he or she can supervise you more
closely to check that your condition is being
controlled.

If you have been advised to have a flu
vaccination
You can be vaccinated at any time, even if you’re
using Relenza to help prevent you from getting flu.

If you use inhaled medication for your asthma
or other breathing problem, read the next part
of this leaflet — Using Relenza with inhaled
medication for breathing problems — carefully,
before you use Relenza.

Pregnancy and breast-feeding

When to start using Relenza

If you are breast-feeding, pregnant, or if you
could be pregnant:

If you have flu, for maximum benefit, you should
start using Relenza as soon as possible when you
get flu symptoms:
• for adults, within 48 hours after the first
symptoms
• for children, within 36 hours after the first
symptoms.

➔ Talk to your doctor before you use Relenza.
There is only limited information about the safety
of Relenza for pregnant women. Although there
is no evidence so far that Relenza harms unborn
babies, your doctor may advise you not to use it
during pregnancy.
You should not breast-feed while you are using
Relenza. The active ingredient (zanamivir) could
get into breast milk.

Driving and using machines
Relenza should not affect your ability to drive or
use machines.

Important information about some
of the ingredients of Relenza

To help prevent flu
If someone in your household has flu, to help
prevent you getting it, you should start using
Relenza as soon as possible after you have come
into contact with them:
• For adults and children, within 36 hours of
contact with the infected person.
If there is a flu outbreak in your local community,
follow your doctor’s advice on when to start using
Relenza.

How much Relenza to use

Relenza contains lactose and milk protein
Relenza contains a sugar called lactose, and may
contain milk protein.

The amount of Relenza you use depends on
whether you already have flu, or you are using
Relenza to help prevent flu.

If you have an intolerance to lactose or any other
sugars, or to milk protein:
Don’t use Relenza. Ask your doctor for advice
about treating or preventing flu.

If you have flu:
• Adults and children (aged 5 years or more): the
usual dose is 2 inhalations (2 blisters) twice a
day for 5 days.



3 How to use Relenza
Always use Relenza exactly as your doctor has
told you to. Check with your doctor or pharmacist
if you’re not sure.
Relenza is a powdered medicine, which you inhale
into your lungs through your mouth, using the
Diskhaler™ device. The powder is contained in
blisters on a Rotadisk™ — a foil disk which you
load into the Diskhaler.
The medicine in the Rotadisks must only be
inhaled using the Diskhaler device.
Don’t give Relenza to children under 5 years old.

To help prevent flu:
• If someone in your household has flu:
Adults and children (aged 5 years or more): the
usual dose is 2 inhalations (2 blisters) once a day
for 10 days.
If there is a flu outbreak in your local community:
• Adults and children (aged 5 years or more): The
recommended dose is 2 inhalations (2 blisters)
once a day for up to 28 days

If you use more Relenza than
you should
If you accidentally use too much Relenza, it’s

unlikely to cause you any problems.
But if you’re worried, or you feel unwell, especially
if you have asthma or other lung problems:
Ask your doctor for advice.



If you forget to use Relenza
If you forget a dose of Relenza, take your usual dose
as soon as you remember, then carry on as before.
Don’t use a double dose to make up for a
forgotten dose.

If you stop using Relenza
For treating flu, it’s important that you complete
the full course of treatment (normally 5 days),
even if you are feeling better. Otherwise, the flu
symptoms may come back.
If you think you may want to stop your Relenza
treatment early:
Ask your doctor for advice.



There’s a step-by-step guide on the other side of
this leaflet, showing you how to use the Relenza
Diskhaler.
Read it carefully before you use your first dose. If
you’re still not sure how to use the Diskhaler, ask
your pharmacist to go through the instructions
with you.

4 Possible side effects
Like all medicines, Relenza can cause side effects,
although not everybody gets them.

Conditions you need to look out for:
Severe allergic reactions
These are rare and affect less than 1 in 1,000
people using Relenza. Signs include:
Raised and itchy rash (hives).
Swelling, sometimes of the face, mouth or throat,
causing difficulty in breathing.
Collapse.
If you get any of these symptoms:
• Contact your doctor immediately.

Serious skin reactions
These side effects are rare and may affect less
than 1 in 1,000 people using Relenza:
Skin rash, which may blister, and looks like small
targets (central dark spots surrounded by a paler
area, with a dark ring around the edge - erythema
multiforme), a widespread rash with blisters and
peeling skin, particularly around the mouth, nose,
eyes and genitals (Stevens-Johnson Syndrome),
extensive peeling of the skin on much of the body
surface – (toxic epidermal necrolysis).
If you notice any of these symptoms contact a
doctor immediately. Stop taking Relenza.
Other common side effects
These affect less than 1 in 10 people using Relenza:
Skin Rash
Other uncommon side effects
These affect less than 1 in 100 people using
Relenza:
Tightness of the throat or chest, feeling short of
breath, or sudden difficulty in breathing. If you
have lung disease (such as asthma or COPD), you
may need to be monitored while you’re using
Relenza in case you get this side effect.
Swelling of the face, mouth or throat
Hives (itchy bumps on your skin).
Fainting and feeling lightheaded
If you are feeling unwell when you take Relenza
you may faint or become lightheaded after
inhaling Relenza. You must sit down in a relaxed
position before inhaling the dose of Relenza, and
you must only hold your breath for as long as is
comfortable after inhaling the dose.
If you are feeling unwell, you are advised to have
someone with you while you are inhaling the dose
of Relenza.
If you get any of these effects:

➔ Stop using Relenza and get medical help
immediately. Contact your doctor or the
nearest hospital emergency
department.

TURN OVER

10000000114909

BACK PAGE
TYPE SIZE: 7.5/8.5
HORIZONTAL SCALE: 100%

Page 1 of 1

Sudden changes in behaviour, hallucinations and
fits
During treatment with Relenza, changes in behaviour
such as confusion and unresponsiveness have
occurred. Some people may also have hallucinations
(seeing, hearing, or feeling things not there) or fits
(seizures) which can lead to loss of consciousness.
Parents should be especially careful to watch out for
these symptoms if their child or teenager has flu.
These symptoms have been seen in people with flu
who were not taking Relenza. Therefore it is not
known if Relenza played a part in causing them.
If you get any of these symptoms:

What Relenza looks like and contents
of the pack

➔ Contact your doctor immediately.

Not all pack sizes may be marketed.

If you get other side effects

Marketing Authorisation Holder
and Manufacturer



If you notice any side effects not listed in this
leaflet please tell your doctor or pharmacist.

5 How to store Relenza
Keep Relenza out of the reach and sight of
children.
Don’t use Relenza or the Diskhaler after the
expiry date which is stated on the pack.
Don’t store Relenza above 30°C.
Relenza Rotadisks should not be disposed of
via waste water or household waste. Ask your
pharmacist how to dispose of medicines no longer
required. These measures will help to protect the
environment.

6 Further information
What Relenza contains
The active substance is zanamivir (5 mg per dose).
The other ingredient is lactose monohydrate
(which contains milk protein).
10000000114909

v1

Relenza powder is contained in the four blisters
on the silver-coloured foil disk, called a Rotadisk.
Each blister contains 5 mg of zanamivir. The
medicine is inhaled through the mouth from the
Rotadisk using a plastic device called a Diskhaler.
Relenza is supplied in two types of pack:
• a 1-day starter pack containing one Relenza
Rotadisk and one Diskhaler
• a 5-day treatment pack containing five Relenza
Rotadisks and one Diskhaler

1

© 2013 GlaxoSmithKline group of companies

Take one quick, deep breath in through the
mouthpiece. Hold this breath for a few seconds.

Keep the Diskhaler horizontal

Remove the Diskhaler from your mouth.
Carry on holding your breath for a few more seconds
or as long as is comfortable.

Don’t do this until just before you inhale a dose.

3

The Rotadisk fits into the Diskhaler
The Rotadisk fits onto the wheel of the
Diskhaler.
Each of the four blisters on the Rotadisk
contains a single dose of Relenza.

4
• Don’t pierce any of the blisters on the Rotadisk before you
load it onto the Diskhaler.

Don’t put the Diskhaler into your mouth yet.
Breathe out as far as is comfortable, keeping the
Diskhaler away from your mouth. Don’t blow into the
Diskhaler. If you do, you’ll blow the powder out of
the Rotadisk.
Place the mouthpiece between your teeth. Close your
lips firmly around the mouthpiece.
Don’t bite the mouthpiece. Don't block the airholes
on the side of the mouthpiece.

To get your dose ready to inhale:
Refer to the
step-by-step guide

Important:

7

Push the white tray back
into the main body.

If you’re not ready to inhale a dose of Relenza
straight away, replace the blue cover.

Hold the white sliding
tray as shown and pull it
out until it stops.

Hinged lid

Product name:
Relenza 5 mg
Reference number: 10949/0327

Relenza, Diskhaler and Rotadisk are registered
trademarks of the GlaxoSmithKline group of
companies.

2

Piercing needle
This pierces the blisters on the Rotadisk,
to make the medicine ready to inhale.

Please be ready to give the following information:

5

Wheel
The Rotadisk fits onto this.
Finger grip

0800 198 5000 (UK Only)

Leaflet date: March 2013

Remove the blue cover.
Check that the
mouthpiece is clean,
inside and outside.

Mouthpiece
(with a small airhole on each side)

Main body

To inhale your dose of Relenza:

To load a Rotadisk into the Diskhaler:

Sliding tray

Other formats:
To listen to or request a copy of this leaflet in Braille,
large print or audio please call, free of charge:

This is a service provided by the Royal National
Institute of Blind People.

Cover

Don’t take it apart until you have
looked at the step-by-step guide.

Marketing Authorisation Holder:
Glaxo Wellcome UK Ltd trading as
GlaxoSmithKline UK, Stockley Park West,
Uxbridge, Middlesex, UB11 1BT.
Manufacturer:
Glaxo Wellcome Production, Zone Industrielle
No.2, 23 Rue Lavoisier, 27000 Evreux, France.

Step-by-step guide to using your Relenza Diskhaler

The Diskhaler has three parts:

Gently squeeze the
finger grips on the sides
of the white tray.

6

Hold the Diskhaler
horizontally.

Remove the tray from
the main body.

Flip the lid up as far
as it will go.

The white tray should
come out easily.

The lid must be fully
vertical, to make sure
that the blister is
pierced at both the
top and bottom.

Place a new Relenza
Rotadisk on the wheel.

• You can keep a Rotadisk on the Diskhaler between doses, but
don’t pierce a blister until just before you inhale your dose.

Make sure the printed
side is up, with the
blisters facing
downwards.

• Keep the Diskhaler clean. Wipe the mouthpiece with a tissue
after you use it, and replace the blue cover between uses.

The blisters fit into the
holes in the wheel.

To prepare the next blister (the second part of your dose):

8

Pull the white tray out as far as it will go (don’t
remove it completely), then push it back in again.
This will turn the wheel so the next blister will appear.
Repeat if necessary until a full blister is positioned
under the piercing needle.
Repeat steps 6 and 7 to inhale the medicine.

9

After you’ve inhaled the full dose (normally two blisters):
Wipe the mouthpiece with a tissue and replace the blue
cover. It’s important to keep the Diskhaler clean.

Keep the Diskhaler
horizontal

Push the lid back down.
Your Diskhaler is now ready for use.
Keep it horizontal until you have
inhaled your dose.
If you use other inhaled medication, make sure
you read ‘Using Relenza with inhaled medication
for breathing problems’ in Section 2 of this leaflet.

To replace the Rotadisk:

10

When all four blisters are empty, remove the Rotadisk from
the Diskhaler and insert a new one, using steps 1 to 5.

1 What Relenza is and what it is used for

Package Leaflet: Information for the User

2 Before you use Relenza

zanamivir
Read all of this leaflet carefully before you start
using this medicine.
Keep this leaflet. You may need to read it again.
If you have any questions, ask your doctor or
pharmacist.
This medicine has been prescribed for you. Don’t
pass it on to others. It may harm them, even if
their symptoms are the same as yours.
If you have serious
side effects, or if
you notice any side
effects not listed
in this leaflet, tell
your doctor or
pharmacist.

Don’t use Relenza:

4 Possible side effects

• if you’re allergic (hypersensitive) to
zanamivir
• if you’re allergic (hypersensitive) to lactose
or milk protein.

5 How to store Relenza

Take special care with Relenza

6 Further information

If you feel tightness in your throat or
chest when you use Relenza
In very rare cases, Relenza can cause a
reaction including:
• tightness of the throat and chest
• difficulty breathing.
If you get any of these symptoms when you
use Relenza:
➔ Stop using Relenza and get medical help
immediately. Contact your doctor or the
nearest hospital emergency department.
Don’t give Relenza to children under 5 years old.
If you have asthma, or other problems
with your lungs or your breathing
Your doctor needs to know if you have:
• asthma
• other lung disease that causes breathing
problems — for example, emphysema,
chronic obstructive pulmonary disease
(COPD), or chronic bronchitis.
➔ Tell your doctor before you use Relenza,
so that he or she can supervise you more
closely to check that your condition is
being controlled.

3 How to use Relenza

5 mg per dose, inhalation powder,
pre-dispensed

Using Relenza with inhaled
medication for breathing problems

2 Before you use Relenza

1 What Relenza is and what
it is used for

Relenza contains zanamivir, which belongs to
a group of medicines called antivirals.
Relenza is used to treat flu (influenza virus
infection). It reduces the symptoms of flu,
and helps you recover more quickly.
Relenza is also used to help prevent you from
getting flu, during a flu outbreak.
Adults and children aged 5 years or more can
be treated with Relenza.
Relenza needs to be inhaled (breathed in)
into the lungs, because it is poorly absorbed
into the body if it is swallowed. The flu virus
infects the lungs, and when you inhale
Relenza it works directly on the virus inside
your lungs.
Relenza is not a substitute for flu
vaccination. You still need to talk to your
doctor about whether you need to be
vaccinated against flu.

If you use inhaled medication for your asthma
or other breathing problem, read the next part
of this leaflet — Using Relenza with inhaled
medication for breathing problems — carefully,
before you use Relenza.

If you use inhaled medication for asthma or
any other breathing problem, carry on using
your inhaler(s) at the usual times.
• If you have been advised to use Relenza at
the same time of day as your other inhaled
medication, use the other medication a
few minutes before you use Relenza.
• Make sure you have your fast-acting
‘reliever’ inhaler (such as salbutamol) to
hand when you use Relenza.
In very rare cases, Relenza can cause a
reaction including:
• tightness of the throat and chest
• difficulty breathing.
If you get any of these symptoms when you
use Relenza:
➔ Stop using Relenza. Use your fast-acting
‘reliever’ inhaler to help your breathing.
Get medical help immediately. Contact
your doctor or the nearest hospital
emergency department.

Using other medicines
Please tell your doctor or pharmacist if you
are taking or have recently taken any other
medicines, including medicines obtained
without a prescription.
If you use inhaled medication for asthma or
other breathing problems, make sure you
have read the advice above.
If you have been advised to have a flu
vaccination
You can be vaccinated at any time, even if
you’re using Relenza to help prevent you
from getting flu.

Pregnancy and breast-feeding
If you are breast-feeding, pregnant, or if you
could be pregnant:
➔ Talk to your doctor before you use
Relenza.
There is only limited information about the
safety of Relenza for pregnant women.
Although there is no evidence so far that
Relenza harms unborn babies, your doctor
may advise you not to use it during
pregnancy.
You should not breast-feed while you are
using Relenza. The active ingredient
(zanamivir) could get into breast milk.

The medicine in the Rotadisks must only be
inhaled using the Diskhaler device.

When to start using Relenza

• Adults and children (aged 5 years or
more): The recommended dose is
2 inhalations (2 blisters) once a day for up
to 28 days

If you have flu, for maximum benefit, you
should start using Relenza as soon as possible
when you get flu symptoms:

If you use more Relenza than you
should

• for adults, within 48 hours after the first
symptoms

If you accidentally use too much Relenza, it’s
unlikely to cause you any problems.

• for children, within 36 hours after the first
symptoms.

But if you’re worried, or you feel unwell,
especially if you have asthma or other lung
problems:
➔ Ask your doctor for advice.

Don’t give Relenza to children under 5 years old.

Relenza should not affect your ability to
drive or use machines.

To help prevent flu
If someone in your household has flu, to
help prevent you getting it, you should start
using Relenza as soon as possible after you
have come into contact with them:

Important information about some
of the ingredients of Relenza

• For adults and children, within 36 hours of
contact with the infected person.

Relenza contains lactose and milk protein
Relenza contains a sugar called lactose, and
may contain milk protein.
If you have an intolerance to lactose or any
other sugars, or to milk protein:
➔ Don’t use Relenza. Ask your doctor for
advice about treating or preventing flu.

If there is a flu outbreak in your local
community, follow your doctor’s advice on
when to start using Relenza.

Driving and using machines

3 How to use Relenza
Always use Relenza exactly as your doctor
has told you to. Check with your doctor or
pharmacist if you’re not sure.
Relenza is a powdered medicine, which you
inhale into your lungs through your mouth,
using the Diskhaler™ device. The powder is
contained in blisters on a Rotadisk™ — a foil
disk which you load into the Diskhaler.

If there is a flu outbreak in your local community:

How much Relenza to use
The amount of Relenza you use depends on
whether you already have flu, or you are
using Relenza to help prevent flu.
If you have flu:
• Adults and children (aged 5 years or
more): the usual dose is 2 inhalations
(2 blisters) twice a day for 5 days.
To help prevent flu:
• If someone in your household has flu:
Adults and children (aged 5 years or
more): the usual dose is 2 inhalations
(2 blisters) once a day for 10 days.

If you forget to use Relenza
If you forget a dose of Relenza, take your
usual dose as soon as you remember, then
carry on as before.
Don’t use a double dose to make up for a
forgotten dose.

If you stop using Relenza
For treating flu, it’s important that you complete
the full course of treatment (normally 5 days),
even if you are feeling better. Otherwise, the flu
symptoms may come back.
If you think you may want to stop your
Relenza treatment early:

➔ Ask your doctor for advice.
There’s a step-by-step guide on the other
side of this leaflet, showing you how to use
the Relenza Diskhaler.
Read it carefully before you use your first
dose. If you’re still not sure how to use the
Diskhaler, ask your pharmacist to go through
the instructions with you.

461
1
Relenza

TYPE SIZE: 8.0/9.1
HORIZONTAL SCALE: 100%

K

10000000112462
GSK-AUS-Boronia-AUBOR
United Kingdom-GBR

LFT017

2

Boronia - Additional Artwork Information Panel
Component Name

RELENZA ROTADISK 5MG 20D LFT UK/TH/MM

Component No.

10000000112462

Site Change No.

201034477

Specification No.

TLFT010

Note to Supplier: N/A

Front
Page 1 of 2

4 Possible side effects
Like all medicines, Relenza can cause side
effects, although not everybody gets them.

Conditions you need to look out for:
Severe allergic reactions
These are rare and affect less than 1 in
1,000 people using Relenza. Signs include:
Raised and itchy rash (hives).
Swelling, sometimes of the face, mouth or
throat, causing difficulty in breathing.
Collapse.
If you get any of these symptoms:
• Contact your doctor immediately.

Serious skin reactions
These side effects are rare and may affect
less than 1 in 1,000 people using Relenza:
Skin rash, which may blister, and looks like
small targets (central dark spots surrounded
by a paler area, with a dark ring around the
edge - erythema multiforme), a widespread
rash with blisters and peeling skin,
particularly around the mouth, nose, eyes
and genitals (Stevens-Johnson Syndrome),
extensive peeling of the skin on much of the
body surface – (toxic epidermal necrolysis).
If you notice any of these symptoms contact a
doctor immediately. Stop taking Relenza.
Other common side effects
These affect less than 1 in 10 people using
Relenza:
Skin rash
Other uncommon side effects
These affect less than 1 in 100 people using
Relenza:
Tightness of the throat or chest, feeling short
of breath, or sudden difficulty in breathing. If
you have lung disease (such as asthma or

COPD), you may need to be monitored
while you’re using Relenza in case you
get this side effect.
Swelling of the face, mouth or throat
Hives (itchy bumps on your skin).

10000000112462

In this leaflet

Fainting and feeling lightheaded
If you are feeling unwell when you
take Relenza you may faint or become
lightheaded after inhaling Relenza. You must
sit down in a relaxed position before inhaling
the dose of Relenza, and you must only hold
your breath for as long as is comfortable
after inhaling the dose.
If you are feeling unwell, you are advised to
have someone with you while you are
inhaling the dose of Relenza.
If you get any of these effects:

➔ Stop using Relenza and get medical help
immediately. Contact your doctor or the
nearest hospital emergency department.

Sudden changes in behaviour, hallucinations
and fits
During treatment with Relenza, changes in
behaviour such as confusion and
unresponsiveness have occurred. Some people
may also have hallucinations (seeing, hearing,
or feeling things not there) or fits (seizures)
which can lead to loss of consciousness.
Parents should be especially careful to watch
out for these symptoms if their child or
teenager has flu. These symptoms have been
seen in people with flu who were not taking
Relenza. Therefore it is not known if Relenza
played a part in causing them.
If you get any of these symptoms:
➔ Contact your doctor immediately.

If you get other side effects



If you notice any side effects
not listed in this leaflet please
tell your doctor or pharmacist.

turn over

5 How to store Relenza
Keep Relenza out of the reach and sight of
children.
Don’t use Relenza or the Diskhaler after the
expiry date which is stated on the pack.
Don’t store Relenza above 30°C.
Relenza Rotadisks should not be disposed of
via waste water or household waste. Ask your
pharmacist how to dispose of medicines no
longer required. These measures will help to
protect the environment.

6 Further information
What Relenza contains
The active substance is zanamivir (5 mg per
dose).
The other ingredient is lactose monohydrate
(which contains milk protein).

What Relenza looks like and contents
of the pack

10000000112462

Relenza powder is contained in the four
blisters on the silver-coloured foil disk, called
a Rotadisk. Each blister contains 5 mg of
zanamivir. The medicine is inhaled through
the mouth from the Rotadisk using a plastic
device called a Diskhaler.
Relenza is supplied in two types of pack:
• a 1-day starter pack containing one
Relenza Rotadisk and one Diskhaler
• a 5-day treatment pack containing five
Relenza Rotadisks and one Diskhaler
Not all pack sizes may be marketed.

Marketing Authorisation Holder and
Manufacturer
Marketing Authorisation Holder:
Glaxo Wellcome UK Ltd trading as
GlaxoSmithKline UK, Stockley Park West,
Uxbridge, Middlesex, UB11 1BT.
Manufacturer:
Aspen Bad Oldesloe GmbH,
Industriestrasse 32-36, 23843 Bad Oldesloe,
Germany.
Other formats:
To listen to or request a copy of this leaflet in
Braille, large print or audio please call, free of
charge:

Don’t take it apart until you have
looked at the step-by-step guide.

Cover

Remove the blue cover.
Check that the
mouthpiece is clean,
inside and outside.

2

Hold the white sliding
tray as shown and pull
it out until it stops.

Mouthpiece
(with a small airhole on each side)

Main body

To inhale your dose of Relenza:

To load a Rotadisk into the Diskhaler:

1
Sliding tray

Wheel
The Rotadisk fits onto this.
Finger grip
Piercing needle
This pierces the blisters on the Rotadisk,
to make the medicine ready to inhale.

0800 198 5000 (UK Only)
Please be ready to give the following
information:
Product name:
Relenza 5 mg
Reference number: 10949/0327
This is a service provided by the Royal
National Institute of Blind People.
Leaflet date: March 2013
Relenza, Diskhaler and Rotadisk are
registered trademarks of the GlaxoSmithKline
group of companies.
© 2013 GlaxoSmithKline group of companies

Step-by-step guide to using your Relenza Diskhaler

The Diskhaler has three parts:

5

7

Push the white tray back
into the main body.

If you’re not ready to inhale a dose of Relenza
straight away, replace the blue cover.

To get your dose ready to inhale:

Hinged lid
Refer to the
step-by-step guide

Don’t put the Diskhaler into your mouth yet.
Breathe out as far as is comfortable, keeping the Diskhaler
away from your mouth. Don’t blow into the Diskhaler. If
you do, you’ll blow the powder out of the Rotadisk.
Place the mouthpiece between your teeth. Close your lips
firmly around the mouthpiece.
Don’t bite the mouthpiece. Don't block the airholes on the
side of the mouthpiece.
Take one quick, deep breath in through the mouthpiece.
Hold this breath for a few seconds.
Remove the Diskhaler from your mouth.
Carry on holding your breath for a few more seconds or as
long as is comfortable.

Don’t do this until just before you inhale a dose.

3

The Rotadisk fits into the Diskhaler
The Rotadisk fits onto the wheel of the
Diskhaler.
Each of the four blisters on the Rotadisk
contains a single dose of Relenza.

4
Important: • Don’t pierce any of the blisters on the Rotadisk before you
load it onto the Diskhaler.
• You can keep a Rotadisk on the Diskhaler between doses, but
don’t pierce a blister until just before you inhale your dose.
• Keep the Diskhaler clean. Wipe the mouthpiece with a tissue
after you use it, and replace the blue cover between uses.

Gently squeeze the
finger grips on the sides
of the white tray.
Remove the tray from
the main body.
The white tray should
come out easily.

6

Place a new Relenza
Rotadisk on the wheel.
Make sure the printed
side is up, with the
blisters facing
downwards.
The blisters fit into the
holes in the wheel.

Hold the Diskhaler
horizontally.
Flip the lid up as far as
it will go.
The lid must be fully
vertical, to make sure
that the blister is
pierced at both the top
and bottom.

To prepare the next blister (the second part of your dose):

8

Pull the white tray out as far as it will go (don’t remove it
completely), then push it back in again.
This will turn the wheel so the next blister will appear.
Repeat if necessary until a full blister is positioned under
the piercing needle.
Repeat steps 6 and 7 to inhale the medicine.

9

After you’ve inhaled the full dose (normally two blisters):
Wipe the mouthpiece with a tissue and replace the blue
cover. It’s important to keep the Diskhaler clean.

Keep the Diskhaler
horizontal

Push the lid back down.
Your Diskhaler is now ready for use.
Keep it horizontal until you have inhaled your
dose.
If you use other inhaled medication, make sure
you read ‘Using Relenza with inhaled medication
for breathing problems’ in Section 2 of this leaflet.

To replace the Rotadisk:

10

When all four blisters are empty, remove the Rotadisk from
the Diskhaler and insert a new one, using steps 1 to 5.

v2
1
Relenza

TYPE SIZE: 8.0/9.1
HORIZONTAL SCALE: 100%

K

10000000112462
GSK-AUS-Boronia-AUBOR
United Kingdom-GBR

LFT017

Keep the Diskhaler horizontal

2

Boronia - Additional Artwork Information Panel
Component Name

RELENZA ROTADISK 5MG 20D LFT UK/TH/MM

Component No.

10000000112462

Site Change No.

201034477

Specification No.

TLFT010

Note to Supplier: N/A

Back
Page 2 of 2

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Hide