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PROGANDOL XL 8MG TABLETS

Active substance(s): DOXAZOSIN MESILATE / DOXAZOSIN MESILATE

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Package leaflet: Information for the patient

CARDURA® XL 8mg Tablets
(doxazosin mesilate)
Read all of this leaflet carefully before you start taking this
medicine because it contains important information for you.
 Keep this leaflet you may need to read it again.
 If you have any further questions, ask your doctor or
pharmacist.
 This medicine has been prescribed for you only. Do not pass
it on to others. It may harm them, even if their signs of illness
are the same as yours.
 You should take Cardura XL regularly to get the maximum
benefit, even if you are feeling well.
 Most people do not have serious problems when taking
Cardura XL but side effects can occur. If you experience
swelling of the face, tongue or windpipe, see your doctor
immediately. If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects not listed
in this leaflet. See section 4.
 Taking other medicines may sometimes cause problems.
Check with your doctor or pharmacist before taking this or
any other medicines.
 If you are, or are trying to become pregnant, do not take
Cardura XL and tell your doctor or pharmacist.
The name of your medicine is CARDURA XL 8mg Tablets but it will
be referred as Cardura XL throughout this leaflet. Please note that
this leaflet also contains information about other strength
Cardura XL 4mg Tablets.
What is in this leaflet
1. What Cardura XL is and what it is used for
2. What you need to know before you take Cardura XL
3. How to take Cardura XL
4. Possible side effects
5. How to store Cardura XL
6. Contents of the pack and other information

1. What Cardura XL is and what it is used
for
Cardura XL contains the active substance doxazosin mesilate and is
one of a group of medicines called alpha-blockers. It is used to treat
high blood pressure, or the symptoms caused by enlargement of the
prostate gland in men.
Cardura XL can be used to treat high blood pressure (hypertension),
by relaxing blood vessels so that blood passes through them more
easily. This helps to lower blood pressure.
In patients with an enlarged prostate gland, Cardura XL is taken to
treat poor and/or frequent passing of urine. This is common in
patients with an enlarged prostate gland. Cardura XL works by
relaxing muscle around the bladder exit and prostate gland so urine
is passed more easily.

2. What you need to know before you take
Cardura XL
Do not take Cardura XL:
 If you are allergic to doxazosin, other types of quinazolines (such
as prazosin or terazosin), or any of the other ingredients of this
medicine (listed in section 6). This may have been itching,
reddening of the skin or difficulty in breathing
 If you are breast-feeding
 If you have any form of obstruction of the digestive tract
 If you have an enlarged prostate gland (benign prostatic
hyperplasia) and have low blood pressure
 If you have a history of a condition known as ‘orthostatic
hypotension’ which is a form of low blood pressure that causes
you to feel dizzy or light-headed when you stand up from sitting or
lying down
 If you have an enlarged prostate gland with one of the following:
any kind of congestion or blockage in your urinary tract, a
longstanding infection of the urinary tract or you have bladder
stones
 If you have overflow incontinence (you do not feel the urge to
urinate), or anuria (your body is not producing any urine) with or
without kidney problems.
Warnings and precautions
Talk to your doctor or pharmacist before taking Cardura XL as it may
not be suitable for you:
 If you are pregnant or trying to become pregnant
 If you have liver disease
 If you have heart disease
 If you are also taking other medicines
If you are undergoing eye surgery because of cataract (cloudiness of
the lens of the eye), please inform your eye specialist before the
operation that you are using or have previously used Cardura XL.
This is because Cardura XL may cause complications during the
surgery which can be managed if your specialist is prepared in
advance.
If any of these apply to you speak to your doctor before taking this
medicine.

When you start to take Cardura XL you may experience faintness or
dizziness caused by low blood pressure, when getting up from sitting
or lying down. If you feel faint or dizzy, you should sit or lie down until
you feel better and avoid situations where you might fall or hurt
yourself. Your doctor may want to measure your blood pressure
regularly at the start of therapy to reduce the possibility of these
effects happening.
Persistent painful erections may occur very rarely. If this happens you
should contact a doctor immediately.
Before starting treatment with Cardura XL your doctor may perform
tests to rule out other conditions such as prostate cancer that may
cause the same symptoms as benign prostatic hyperplasia.
Children and adolescents
Cardura XL is not recommended for use in children or adolescents
below 18 years as safety and efficacy have not yet been established.
Benign prostate hyperplasia is not relevant in children.
Other medicines and Cardura XL
Tell your doctor or pharmacist if you are taking, have recently taken
or might take any other medicines. There are some medicines that
may interact with Cardura XL:
 Some patients who take alpha-blocker therapy for the treatment
of high blood pressure or prostate enlargement may experience
dizziness or light-headedness, which may be caused by low blood
pressure upon sitting or standing up quickly. Certain patients have
experienced these symptoms when taking drugs for erectile
dysfunction (impotence) with alpha-blockers. In order to reduce
the likelihood that these symptoms occur, you should be on a
regular daily dose of your alpha blocker before you start drugs for
erectile dysfunction.
 Cardura XL may lower your blood pressure even more if you are
already taking other medicines to treat your high blood pressure
such as terazosin and prazosin.
Cardura XL with food and drink
See section 3 How to take Cardura XL
Pregnancy, breast-feeding and fertility
The safety of using Cardura XL during pregnancy has not been
established. If you are pregnant or are planning to have a baby, ask
your doctor or pharmacist for advice before taking this medicine.
Do not take Cardura XL if you are breast-feeding.
Driving and using machines
Take care if you drive or operate machinery. Your tablets may affect
your ability to drive or operate machinery safely, particularly when
you first start to take them. They may make you feel weak or dizzy. If
affected, do not drive or operate machinery and contact your doctor
immediately.

3. How to take Cardura XL
Always take this medicine exactly as your doctor or pharmacist has
told you. Check with your doctor or pharmacist if you are not sure.
Cardura XL is a prolonged release tablet. The medicine is contained
within a non-absorbable shell that has been specially designed to
slowly release the medicine. Once swallowed, doxazosin is slowly
released into the body from the tablet, until the tablet is empty.
Since the empty tablet is eliminated from the body in bowel
movements, you may occasionally observe in the stools, something
that looks like a tablet. This is to be expected and you should not be
concerned.
How to take your medicine
– The recommended dose of Cardura XL is one 4mg prolonged
release tablet taken as a single daily dose each day.
– Your doctor may wish to increase your dose to 8mg. This is the
maximum dose of Cardura XL.
– Swallow Cardura XL whole with water. Do not chew, divide or
crush the tablets.
– Take your tablets as your doctor told you or by following the days
and arrows on the blister foil.
– If you are still not sure, ask your doctor or pharmacist.
– It is important to keep taking your tablets. They help to control
your blood pressure.
– Do not change the dose or stop taking the tablets without first
checking with your doctor.
– Do not wait until your tablets are finished before seeing your
doctor.
If you take more Cardura XL than you should:
Taking too many tablets at once may make you unwell. If several
tablets are taken it may be dangerous. Tell your doctor immediately
or go to your nearest hospital casualty department immediately.
If you forget to take Cardura XL:
Do not worry. If you forget to take a tablet, leave that dose out
completely. Then go on as before. Do not take a double dose to
make up for a forgotten tablet.

4. Possible side effects
Like all medicines, this medicine can cause side effects although not
everybody gets them.
STOP taking Cardura XL and call an ambulance immediately if
you experience any of the following:
 Heart attack
 Weakness of arms, legs or problems speaking which may be
symptoms of a stroke
 Allergic reactions (hypersensitivity). Symptoms include sudden
wheeziness, tightness in the chest, difficulty in breathing, swelling
of the face, tongue or throat, rash or itching (especially the whole
body)

Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You
can also report any side effects directly via the Yellow Card Scheme
at: www.mhra.gov.uk/yellowcard.
By reporting any side effects, you can help provide more information
on the safety of this medicine.

5. How to store Cardura XL




Keep out of the sight and reach of children.
Do not store above 30°C. Store in the original container.
Do not take your tablets after the expiry date which is stated on
the carton and blister label after ‘Exp’. The date refers to the last
day of that month.
The tablet should be swallowed whole to work effectively,
however if you notice any defects (such as broken tablets) consult
your pharmacist immediately.
If your doctor tells you to stop taking the tablets, please take them
back to the pharmacist for safe disposal. Only keep the tablets if
your doctor tells you to.
If the tablets become discoloured or show any other signs of
deterioration, seek the advice of your pharmacist.
Medicines should not be disposed of via wastewater or household
waste. Ask your pharmacist how to dispose of medicines no
longer required. These measures will help to protect the
environment.

Tell your doctor immediately if you experience any of the following
symptoms after taking Cardura XL:
 Feeling your heartbeat (palpitations) (common: may affect up to 1
in 10 people)
 Increased or decreased heartbeat(common: may affect up to 1 in
10 people)
 Shortness of breath, difficulty breathing, wheezing (common: may
affect up to 1 in 10 people)
 Chest pain, angina (uncommon: may affect up to 1 in 100 people)
 Irregular heartbeat (very rare: may affect up to 1 in 10, 000
people)
 Skin rash or itching (especially the whole body) (uncommon: may
affect up to 1 in 100 people)
 Yellowing of the skin or the eyes (jaundice) (very rare: may affect
up to 1 in 10,000 people)
 Low numbers of white blood cells or blood platelets, which may
result in bruising or easy bleeding (very rare: may affect up to 1 in
10,000 people)
 Persistent painful erection of the penis. Seek urgent medical
advice (very rare: may affect up to 1 in 10,000 people)



The following events have been reported in patients being treated
with Cardura XL. If any of these side effects get serious, or if you
notice any side effects not listed in this leaflet, please tell your doctor.

Cardura XL 8mg tablets also contain the following: polyethylene
oxide, sodium chloride, hypromellose, cellulose acetate, magnesium
stearate, macrogol, ammonium hydroxide, titanium dioxide (E171),
black iron oxide (E172), red iron oxide (E172), shellac, n-butyl
alcohol, isopropyl alcohol, and propylene glycol.

Common side effects: may affect up to 1 in 10 people
 dizziness, feeling of spinning or rotation of surroundings (vertigo),
headache
 low blood pressure
 swelling of feet, ankles or fingers
 chest cold, coughing, respiratory tract (nose, throat, lungs)
infection
 nasal stuffiness, sneezing and/or runny nose caused by
inflammation of the lining of the nose (rhinitis)
 stomach/abdominal pains, feeling/being sick
 urinary tract infection, urinary incontinence (inability to control
passing urine), inflammation of the bladder (cystitis)
 sleepiness, general weakness
 indigestion, heartburn, dry mouth
 back pain, painful muscles
 flu-like symptoms
Uncommon side effects: may affect up to 1 in 100 people
 constipation, wind, inflammation of the stomach and intestines
(gastroenteritis) which can cause diarrhoea and vomiting
 pain or discomfort on passing urine, needing to pass urine more
often than usual, blood in urine
 inflammation of the joints (gout), painful joints, general pain
 swelling of the face
 sleeplessness, anxiety, depression
 reduced or altered sense of touch or sensation of the hands and
feet
 increased appetite or loss of appetite, weight gain
 nose bleeds
 ringing in the ears, tremor
 failure/ inability to achieve penile erection
 abnormal results for blood tests which show changes in the way
the liver is working
Rare side effects: may affect up to 1 in 1,000 people
 blockage of the digestive tract
Very Rare side effects: may affect up to 1 in 10,000 people
 faintness or dizziness caused by low blood pressure when getting
up from a sitting or lying position
 hepatitis (liver inflammation) or bile disorder
 hives, hair loss, red or purple patches on the skin, bleeding under
the skin
 tingling or numbness of the hands and feet
 agitation, nervousness
 tiredness, generally feeling unwell
 aggravated wheezing
 muscle cramps, muscle weakness
 blurred vision
 flushing
 disorder in passing urine, needing to pass urine at night,
increased volume of urine passed, increased production of urine
causing an increase in the number of times of passing urine
 discomfort or enlargement of the breasts in men
Not known: frequency cannot be estimated from the
available data
 little or no semen ejaculated at sexual climax, cloudy urine
following sexual climax
 eye problems may occur during eye surgery for cataract
(cloudiness of the lens of the eye). See section 'Warnings and
precautions'.





6. Contents of the pack and other
information
Cardura XL contains 9.70mg of the active ingredient doxazosin
mesilate, equivalent to 8mg of doxazosin in a white, round modified
release tablet, which is, marked ‘CXL 8’ on one side and plain on the
reverse. The tablets are designed to slowly release the drug.

Cardura XL are available in calendar blister packs of 28 tablets.
Manufactured by: Industrias Farmaceuticas Almirall, S.L., Ctra.
Nacional II, Km. 593 08740 Sant Andreu de la barca – Barcelona,
Spain.
Procured from within the EU and repackaged by the Product
Licence holder: B&S Healthcare, Unit 4, Bradfield Road, Ruislip,
Middlesex, HA4 0NU, UK
CARDURA® XL 8mg Tablets; PL 18799/2640

POM

Leaflet date: 18.05.2017
Cardura is a registered trademark of Pfizer group of companies.

Blind or partially sighted?
Is this leaflet hard to see or read?
Call 0208 515 3763 to obtain the
leaflet in a format suitable for you.

Package leaflet: Information for the patient

PROGANDOL® XL 8mg Tablets
(doxazosin mesilate)
Read all of this leaflet carefully before you start taking this
medicine because it contains important information for you.
 Keep this leaflet you may need to read it again.
 If you have any further questions, ask your doctor or
pharmacist.
 This medicine has been prescribed for you only. Do not pass
it on to others. It may harm them, even if their signs of illness
are the same as yours.
 You should take Progandol XL regularly to get the maximum
benefit, even if you are feeling well.
 Most people do not have serious problems when taking
Progandol XL but side effects can occur. If you experience
swelling of the face, tongue or windpipe, see your doctor
immediately. If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects not listed
in this leaflet. See section 4.
 Taking other medicines may sometimes cause problems.
Check with your doctor or pharmacist before taking this or
any other medicines.
 If you are, or are trying to become pregnant, do not take
Progandol XL and tell your doctor or pharmacist.
The name of your medicine is PROGANDOL XL 8mg Tablets but it
will be referred as Progandol XL throughout this leaflet. Please note
that this leaflet also contains information about other strength
Progandol XL 4mg Tablets.
What is in this leaflet
1. What Progandol XL is and what it is used for
2. What you need to know before you take Progandol XL
3. How to take Progandol XL
4. Possible side effects
5. How to store Progandol XL
6. Contents of the pack and other information

1. What Progandol XL is and what it is
used for
Progandol XL contains the active substance doxazosin mesilate and
is one of a group of medicines called alpha-blockers. It is used to
treat high blood pressure, or the symptoms caused by enlargement of
the prostate gland in men.
Progandol XL can be used to treat high blood pressure
(hypertension), by relaxing blood vessels so that blood passes
through them more easily. This helps to lower blood pressure.
In patients with an enlarged prostate gland, Progandol XL is taken to
treat poor and/or frequent passing of urine. This is common in
patients with an enlarged prostate gland. Progandol XL works by
relaxing muscle around the bladder exit and prostate gland so urine
is passed more easily.

2. What you need to know before you take
Progandol XL
Do not take Progandol XL:
 If you are allergic to doxazosin, other types of quinazolines (such
as prazosin or terazosin), or any of the other ingredients of this
medicine (listed in section 6). This may have been itching,
reddening of the skin or difficulty in breathing
 If you are breast-feeding
 If you have any form of obstruction of the digestive tract
 If you have an enlarged prostate gland (benign prostatic
hyperplasia) and have low blood pressure
 If you have a history of a condition known as ‘orthostatic
hypotension’ which is a form of low blood pressure that causes
you to feel dizzy or light-headed when you stand up from sitting or
lying down
 If you have an enlarged prostate gland with one of the following:
any kind of congestion or blockage in your urinary tract, a
longstanding infection of the urinary tract or you have bladder
stones
 If you have overflow incontinence (you do not feel the urge to
urinate), or anuria (your body is not producing any urine) with or
without kidney problems.
Warnings and precautions
Talk to your doctor or pharmacist before taking Progandol XL as it
may not be suitable for you:
 If you are pregnant or trying to become pregnant
 If you have liver disease
 If you have heart disease
 If you are also taking other medicines
If you are undergoing eye surgery because of cataract (cloudiness of
the lens of the eye), please inform your eye specialist before the
operation that you are using or have previously used Progandol XL.
This is because Progandol XL may cause complications during the
surgery which can be managed if your specialist is prepared in
advance.
If any of these apply to you speak to your doctor before taking this
medicine.

When you start to take Progandol XL you may experience faintness
or dizziness caused by low blood pressure, when getting up from
sitting or lying down. If you feel faint or dizzy, you should sit or lie
down until you feel better and avoid situations where you might fall or
hurt yourself. Your doctor may want to measure your blood pressure
regularly at the start of therapy to reduce the possibility of these
effects happening.
Persistent painful erections may occur very rarely. If this happens you
should contact a doctor immediately.
Before starting treatment with Progandol XL your doctor may perform
tests to rule out other conditions such as prostate cancer that may
cause the same symptoms as benign prostatic hyperplasia.
Children and adolescents
Progandol XL is not recommended for use in children or adolescents
below 18 years as safety and efficacy have not yet been established.
Benign prostate hyperplasia is not relevant in children.
Other medicines and Progandol XL
Tell your doctor or pharmacist if you are taking, have recently taken
or might take any other medicines. There are some medicines that
may interact with Progandol XL:
 Some patients who take alpha-blocker therapy for the treatment
of high blood pressure or prostate enlargement may experience
dizziness or light-headedness, which may be caused by low blood
pressure upon sitting or standing up quickly. Certain patients have
experienced these symptoms when taking drugs for erectile
dysfunction (impotence) with alpha-blockers. In order to reduce
the likelihood that these symptoms occur, you should be on a
regular daily dose of your alpha blocker before you start drugs for
erectile dysfunction.
 Progandol XL may lower your blood pressure even more if you
are already taking other medicines to treat your high blood
pressure such as terazosin and prazosin.
Progandol XL with food and drink
See section 3 How to take Progandol XL
Pregnancy, breast-feeding and fertility
The safety of using Progandol XL during pregnancy has not been
established. If you are pregnant or are planning to have a baby, ask
your doctor or pharmacist for advice before taking this medicine.
Do not take Progandol XL if you are breast-feeding.
Driving and using machines
Take care if you drive or operate machinery. Your tablets may affect
your ability to drive or operate machinery safely, particularly when
you first start to take them. They may make you feel weak or dizzy. If
affected, do not drive or operate machinery and contact your doctor
immediately.

3. How to take Progandol XL
Always take this medicine exactly as your doctor or pharmacist has
told you. Check with your doctor or pharmacist if you are not sure.
Progandol XL is a prolonged release tablet. The medicine is
contained within a non-absorbable shell that has been specially
designed to slowly release the medicine. Once swallowed, doxazosin
is slowly released into the body from the tablet, until the tablet is
empty.
Since the empty tablet is eliminated from the body in bowel
movements, you may occasionally observe in the stools, something
that looks like a tablet. This is to be expected and you should not be
concerned.
How to take your medicine
– The recommended dose of Progandol XL is one 4mg prolonged
release tablet taken as a single daily dose each day.
– Your doctor may wish to increase your dose to 8mg. This is the
maximum dose of Progandol XL.
– Swallow Progandol XL whole with water. Do not chew, divide or
crush the tablets.
– Take your tablets as your doctor told you or by following the days
and arrows on the blister foil.
– If you are still not sure, ask your doctor or pharmacist.
– It is important to keep taking your tablets. They help to control
your blood pressure.
– Do not change the dose or stop taking the tablets without first
checking with your doctor.
– Do not wait until your tablets are finished before seeing your
doctor.
If you take more Progandol XL than you should:
Taking too many tablets at once may make you unwell. If several
tablets are taken it may be dangerous. Tell your doctor immediately
or go to your nearest hospital casualty department immediately.
If you forget to take Progandol XL:
Do not worry. If you forget to take a tablet, leave that dose out
completely. Then go on as before. Do not take a double dose to
make up for a forgotten tablet.

4. Possible side effects
Like all medicines, this medicine can cause side effects although not
everybody gets them.
STOP taking Progandol XL and call an ambulance immediately if
you experience any of the following:
 Heart attack
 Weakness of arms, legs or problems speaking which may be
symptoms of a stroke
 Allergic reactions (hypersensitivity). Symptoms include sudden
wheeziness, tightness in the chest, difficulty in breathing, swelling
of the face, tongue or throat, rash or itching (especially the whole
body)
Tell your doctor immediately if you experience any of the following
symptoms after taking Progandol XL:
 Feeling your heartbeat (palpitations) (common: may affect up to 1
in 10 people)
 Increased or decreased heartbeat(common: may affect up to 1 in
10 people)
 Shortness of breath, difficulty breathing, wheezing (common: may
affect up to 1 in 10 people)
 Chest pain, angina (uncommon: may affect up to 1 in 100 people)
 Irregular heartbeat (very rare: may affect up to 1 in 10, 000
people)
 Skin rash or itching (especially the whole body) (uncommon: may
affect up to 1 in 100 people)
 Yellowing of the skin or the eyes (jaundice) (very rare: may affect
up to 1 in 10,000 people)
 Low numbers of white blood cells or blood platelets, which may
result in bruising or easy bleeding (very rare: may affect up to 1 in
10,000 people)
 Persistent painful erection of the penis. Seek urgent medical
advice (very rare: may affect up to 1 in 10,000 people)
The following events have been reported in patients being treated
with Progandol XL. If any of these side effects get serious, or if you
notice any side effects not listed in this leaflet, please tell your doctor.
Common side effects: may affect up to 1 in 10 people
 dizziness, feeling of spinning or rotation of surroundings (vertigo),
headache
 low blood pressure
 swelling of feet, ankles or fingers
 chest cold, coughing, respiratory tract (nose, throat, lungs)
infection
 nasal stuffiness, sneezing and/or runny nose caused by
inflammation of the lining of the nose (rhinitis)
 stomach/abdominal pains, feeling/being sick
 urinary tract infection, urinary incontinence (inability to control
passing urine), inflammation of the bladder (cystitis)
 sleepiness, general weakness
 indigestion, heartburn, dry mouth
 back pain, painful muscles
 flu-like symptoms
Uncommon side effects: may affect up to 1 in 100 people
 constipation, wind, inflammation of the stomach and intestines
(gastroenteritis) which can cause diarrhoea and vomiting
 pain or discomfort on passing urine, needing to pass urine more
often than usual, blood in urine
 inflammation of the joints (gout), painful joints, general pain
 swelling of the face
 sleeplessness, anxiety, depression
 reduced or altered sense of touch or sensation of the hands and
feet
 increased appetite or loss of appetite, weight gain
 nose bleeds
 ringing in the ears, tremor
 failure/ inability to achieve penile erection
 abnormal results for blood tests which show changes in the way
the liver is working
Rare side effects: may affect up to 1 in 1,000 people
 blockage of the digestive tract
Very Rare side effects: may affect up to 1 in 10,000 people
 faintness or dizziness caused by low blood pressure when getting
up from a sitting or lying position
 hepatitis (liver inflammation) or bile disorder
 hives, hair loss, red or purple patches on the skin, bleeding under
the skin
 tingling or numbness of the hands and feet
 agitation, nervousness
 tiredness, generally feeling unwell
 aggravated wheezing
 muscle cramps, muscle weakness
 blurred vision
 flushing
 disorder in passing urine, needing to pass urine at night,
increased volume of urine passed, increased production of urine
causing an increase in the number of times of passing urine
 discomfort or enlargement of the breasts in men
Not known: frequency cannot be estimated from the
available data
 little or no semen ejaculated at sexual climax, cloudy urine
following sexual climax
 eye problems may occur during eye surgery for cataract
(cloudiness of the lens of the eye). See section 'Warnings and
precautions'.

Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You
can also report any side effects directly via the Yellow Card Scheme
at: www.mhra.gov.uk/yellowcard.
By reporting any side effects, you can help provide more information
on the safety of this medicine.

5. How to store Progandol XL








Keep out of the sight and reach of children.
Do not store above 30°C. Store in the original container.
Do not take your tablets after the expiry date which is stated on
the carton and blister label after ‘Exp’. The date refers to the last
day of that month.
The tablet should be swallowed whole to work effectively,
however if you notice any defects (such as broken tablets) consult
your pharmacist immediately.
If your doctor tells you to stop taking the tablets, please take them
back to the pharmacist for safe disposal. Only keep the tablets if
your doctor tells you to.
If the tablets become discoloured or show any other signs of
deterioration, seek the advice of your pharmacist.
Medicines should not be disposed of via wastewater or household
waste. Ask your pharmacist how to dispose of medicines no
longer required. These measures will help to protect the
environment.

6. Contents of the pack and other
information
Progandol XL contains 9.70mg of the active ingredient doxazosin
mesilate, equivalent to 8mg of doxazosin in a white, round modified
release tablet, which is, marked ‘CXL 8’ on one side and plain on the
reverse. The tablets are designed to slowly release the drug.
Progandol XL 8mg tablets also contain the following:
polyethylene oxide, sodium chloride, hypromellose, cellulose acetate,
magnesium stearate, macrogol, ammonium hydroxide, titanium
dioxide (E171), black iron oxide (E172), red iron oxide (E172),
shellac, n-butyl alcohol, isopropyl alcohol, and propylene glycol.
Progandol XL are available in calendar blister packs of 28 tablets.
Manufactured by: Industrias Farmaceuticas Almirall, S.L., Ctra.
Nacional II, Km. 593 08740 Sant Andreu de la barca – Barcelona,
Spain.
Procured from within the EU and repackaged by the Product
Licence holder: B&S Healthcare, Unit 4, Bradfield Road, Ruislip,
Middlesex, HA4 0NU, UK
PROGANDOL® XL 8mg Tablets; PL 18799/2640

POM

Leaflet date: 18.05.2017
Progandol is a registered trademark of Pfizer group of companies.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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