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PRIPSEN PIPERAZINE PHOSPHATE POWDER
piperazine phosphate powder
Important information about Pripsen Powder
• This medicine is used to get rid of
threadworms (pinworms) and roundworms.
• It can be given to adults, children and infants
over 3 months.
• Two separate doses are needed as a follow-up
dose is required. See section 3.
• Follow the dosage instructions carefully.
Children of different ages need different
amounts. See section 3.
Do not use…..
• In the first 3 months of pregnancy.
Talk to your doctor…..
• If more than 3 months pregnant.
Now read the rest of the leaflet before
you use this medicine. It includes other
information which might be especially
important for you.
• Keep this leaflet. You may need to read it again.
• Ask your pharmacist if you need any more
information or advice.
• If any of the side effects gets serious, or if
you notice any side effects not listed in this
leaflet, please tell your doctor or pharmacist.
1. What the medicine is for
Pripsen is a powder for oral suspension. It contains
piperazine which paralyses the worms which are
then passed out by the purging effect of the
senna. The first dose treats the adult worms,
but the eggs are left behind. The second dose
treats the young worms that have hatched from
the eggs before they are old enough to have
laid any eggs themselves.
Pripsen is used to get rid of threadworms
(pinworms) and roundworms.
2. Before you use this medicine
Do not use the medicine if you or
• Are allergic to any of the ingredients listed in
• Have kidney or liver disease.
• Have epilepsy.
• Are suffering from a painful stomach ache,
colic or have recently suffered from severe
diarrhoea or vomiting.
Talk to your doctor or pharmacist if
you or your child are taking …..
• Pyrantel pamoate, which may be in other
medicines for getting rid of worms.
• Sedative or anti-depressant medicines.
• Diuretics, which help remove fluids from the
• Cardiac glycosides for heart problems.
Pregnant or breastfeeding ….
• Ask your doctor or pharmacist for advice
before using this medicine if you are
pregnant, might be pregnant or are
• Use within the first 3 months of pregnancy is
not advised. Unless your doctor tells you that
you need immediate treatment, you should
wait until after the baby is born.
• If you are breastfeeding it is best to feed the
baby immediately before taking Pripsen. Allow
8 hours before breastfeeding is resumed.
During this 8 hour period, milk should be
expressed at the usual feeding times and
6. Further information
What is in this medicine
Dose for treating threadworm and
Adults, the elderly and children over 6
Children from 1 – 6 years
One level 5ml spoonful of powder (two
thirds of a sachet).
Infants from 3 months to 1 year
One level 2.5ml spoonful of powder (one
third of a sachet).
Follow up dose:
• For threadworm take a second dose 14
days after the first dose.
• For roundworm take a second dose one
month after the first dose. The dose may need
to be repeated at monthly intervals for up to 3
If you use too much
If you accidentally take too much, see a
doctor straight away. Take the pack with you to
show which medicine you have swallowed.
Like all medicines, Pripsen can have side
effects, although these don’t affect everyone.
Important side effect
If these severe side effects happen, stop taking
your medicine and see a doctor as soon as
• Stevens Johnson Syndrome (severe rashes on
the skin and ulceration of the eyes, mouth,
nose and genitals), swelling and wheals on
the skin, joint pain and fever.
Other possible side effects are:
• Allergic reactions such as rash, itching,
• Mild gastrointestinal upsets such as nausea,
vomiting, stomach ache or diarrhoea.
• Drowsiness, confusion, muscle spasms,
dizziness, unsteadiness, tremors, jerky
movement, slow reflexes, involuntary eye
movements, vertigo and blurred vision.
If you notice these or any other side effect not
included above, stop use and tell your doctor or
pharmacist. They will tell you what to do.
• Keep it out of the reach and sight of children.
• Do not store above 25°C.
• Store in a dry place.
• Do not use after the expiry date shown on the
carton. The expiry date refers to the last day
of that month.
• Medicine should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of any unused
medicine. These measures will help to protect
• The correct dose of powder should be stirred
into a small glass of milk or water and drunk
• It should be taken at bedtime by adults and in
the morning by children.
• For children under 10 years only one dual
dose treatment should be given in any 28 day
period without asking your doctor.
4. Possible side effects
5. Storing this medicine
3. How to use this medicine
The active ingredients per sachet are:
piperazine phosphate 4g and standardized
The other ingredients are: saccharin, vanilla
flavour, raspberry flavour, caramel flavour, red
colour (carminic acid) E120.
What the medicine looks like
Pripsen is a pink powder which smells of
raspberries. It is supplied in packs of 2 sachets.
Marketing authorisation holder
Thornton and Ross Ltd., Huddersfield,
HD7 5QH, UK.
Famar France, 1 Avenue du Champ du Mars,
F45072, Orleans, Cedex 02, France.
This leaflet was revised in March 2008
Pripsen is a trade mark of Thornton and Ross Ltd.
Health and Hygiene Information
What are threadworms (pinworms)?
Threadworms, as their name suggests, are
threadlike, white worms about a centimetre
long. They can often be seen in the stools or on
the toilet paper, where they look like threads of
Threadworms are very common, especially in
children. Experts have estimated that as many
as four out of every ten children suffer from
threadworms before their tenth birthday. People
of all ages can catch threadworms, however
careful they are about their cleanliness.
Although this disorder is a nuisance, it is
harmless and easily treated.
Where do threadworms come from?
Threadworms cannot be caught from pets since
they only live in humans. Even the cleanest
household can catch threadworms because the
microscopic eggs are easily carried on clothes and
bed linen, on skin, under fingernails and on food.
Threadworms are passed from person to
person very easily so it is important to follow a
few simple hygiene rules. If followed carefully
for six weeks they will reduce the risk of
threadworms coming back into your home. The
most important rule is to treat the whole family
on the same day and repeat after 14 days.
Roundworms are generally much longer than
threadworms and can have a longer lifecycle.
They can be caught from several sources e.g. pets
or soil. Where roundworm is suspected, follow
the instructions given in section 3 of the leaflet.
Home Hygiene Rules
• Fingers and nails must be washed and
scrubbed with a nailbrush after each visit to
the toilet and before each meal.
• Disinfect the toilet seat, toilet handle or chain
and the door handle regularly.
• Vacuum bedrooms daily, damp-dust surfaces
and try not to raise dust.
Personal Hygiene Rules
• Keep finger nails cut short.
• Wear pyjamas or pants in bed.
• Bathe each morning, remembering to wash
your bottom thoroughly.
• Have a towel for sole use.
• Change regularly and wash clothes and bed
Follow these hygiene rules for six weeks from the
date of the family taking the first dose of Pripsen.
First dose taken………….........…………(date)
Second dose taken……...…...…………..(date)
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.