Skip to Content



PDF options:  View Fullscreen   Download PDF

PDF Transcript

24 mm

Read all of this leaflet carefully before you start taking
this medicine because it contains important information
for you.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or
• This medicine has been prescribed for you only. Do not
pass it on to others. It may harm them, even if their signs
of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist.
This includes any possible side effects not listed in this
leaflet. See Section 4.
What is in this leaflet
1. What Penicillin tablets are and what they are
used for
2. What you need to know before you take Penicillin
3. How to take Penicillin tablets
4. Possible side effects
5. How to store Penicillin tablets
6. Contents of the pack and other information

1. What Penicillin tablets are and what they are
used for
The name of your medicine is Phenoxymethylpenicillin 250mg
tablets BP referred as Penicillin tablets in this leaflet. The
active ingredient is Phenoxymethylpenicillin potassium.
• Phenoxymethylpenicillin belongs to a group of medicines
called penicillins, which are used to fight bacteria that
cause infections.
• These tablets are used to treat a wide range of bacterial
infections of the ear, throat, respiratory tract, skin and soft
• It may also be used to prevent infections such as rheumatic
fever or chorea (a group of disorders characterized by
brief rapid involuntary movements of limbs, face, trunk and

2. What you need to know before you take
Penicillin tablets
Do not take this medicine if you:
• are allergic to phenoxymethylpenicillin, any other
penicillins or cephalosporins or any other ingredients
(listed in Section 6)
Warnings and Precautions
Talk to your doctor or pharmacist before taking this medicine,
if you have or have had any medical conditions, and
especially if you:
• are suffering from severe illness, nausea, vomiting,
stomach bloating/cramping or heart problems.
• have impaired kidney function.
Other medicines and Penicillin tablets
Tell your doctor or pharmacist if you are taking, have recently
taken or might take any other medicines.
Examples of medicines which can affect phenoxymethylpenicillin are:
• tetracycline, neomycin, erythromycin, chloramphenicol
(other types of antibiotics)
• probenecid (used to treat gout - painful inflammation of
the joints)
• methotrexate (a drug used to treat cancer and psoriasis
– a chronic skin disease)
• anti-coagulants (medication used to prevent blood clots
e.g. Warfarin)
Phenoxymethylpenicillin Solution with food and drink
• Guar gum (used as a thickening agent and normally found
in puddings and ice-cream and benefiber) can reduce
the absorption of phenoxymethylpenicillin.
Pregnancy, breast-feeding and fertility
• If you are pregnant or breast-feeding, think you may be
pregnant or are planning to have a baby, ask your doctor
or pharmacist for advice before taking this medicine.

220 mm

220 x 140 mm

Driving and using machines
• This medicine should not affect your ability to drive or to
use machinery.

3. How to take Penicillin tablets
• Always take these tablets exactly as advised by your doctor.
You should check with your doctor or pharmacist if you are
not sure.
• The dosage and duration of treatment will depend on the
type and severity of the infection.
• It should be given in divided doses (4 times a day). Take
this medicine when your stomach is empty. This means at
least 30mins before food and preferably not less than two
hours after food.
Adults including the elderly and children over 12 years
The usual adult dosage is 125mg or 250mg every six hours
depending on your condition.
6 to 12 years of age: 250mg every 6 hours
1 to 5 years of age: 125mg every 6 hours
Infants (up to 1 year): 62.5mg every 6 hours
Long-term treatment:
Up to 6 years of age: 125mg twice daily
6 to 12 years of age: 250mg twice daily
The liquid form of this medicine may be more suitable for
children under 6 years of age and those with difficulty in
For preventing the recurrence of rheumatic fever or chorea:
The usual dose is 250mg twice daily on a continuing basis.
For the prevention of infection in patients without a spleen or
patients with sickle cell disease:
For adults and children over 12 years, the dosage is 500mg
every 12 hours.
For children aged between 6 and 12 years, the dosage is
250mg every 12 hours and for children below 5 years, the
dosage is 125mg every 12 hours.
For children over 12 years the dose should not exceed the
maximum adult doses.
For elderly, the dosage is as for the adult. The dosage should
be lowered in poor renal function.

140 mm


head) from recurring bacterial endocarditis in susceptible
patients before surgery and to prevent infections in
patients without a spleen or in patients with sickle cell



24 mm

4. Possible Side Effects
Like all medicines, this medicine may sometimes cause side
effects, although not everybody gets them.
STOP TAKING this medicine and tell your doctor immediately
if you suffer from any of the following:
• an allergic reaction (symptoms include shortness of breath,
dizziness skin rash or itching, hives, swelling of lips, face
or tongue, chills or fever, or painful joints)
• unusual bleeding or bruising
• seizures
• Pseudomembranous colitis (severe bloody diarrhoea)
• peeling/blistering of the skin
• Serum sickness-like reactions (characterised by fever,
chills, joint pains and oedema)

5. How to store Penicillin tablets
• Keep this medicine out of the sight and reach of children.
• Blisters: Do not store above 25ºC. Store in the original
Containers: Do not store above 25ºC. Keep the container
tightly closed.
• Do not use this medicine after the expiry date which is
stated on the label or carton (EXP.). The expiry date refers
to the last day of that month.
• Do not throw away any medicines via wastewater or
household waste. Ask your pharmacist how to throw away
medicines you no longer use. These measures will help
protect the environment.

6. Contents of the pack and other information
What these tablets contain
• The active substance is phenoxymethylpenicillin (as
phenoxymethylpenicillin potassium).
• The other ingredients are maize starch, magnesium
stearate, povidone, hypromellose, purified talc, macrogol
and the colouring agent titanium dioxide (E171).
What these tablets look like and contents of the pack
• The tablets are White to off white, round, biconvex filmcoated tablets with BL/250 embossed on one side.
• The tablets come in packs containing 28 or 1000 tablets.
• Not all pack sizes may be marketed.
Marketing Authorisation Holder
Name and address: Bristol Laboratories Ltd.
Unit 3, Canalside, Northbridge Road,
Berkhamsted, Hertfordshire,
HP4 1EG, United Kingdom
0044 (0) 1442 200922
0044 (0) 1442 873717
Wave Pharma Limited,
4th Floor, Cavendish House,
369 Burnt Oak Broadway,
Edgware, HA8 5AW,
United Kingdom
Phenoxymethylpenicillin 250 mg Tablets BP;
PL 17907/0033
This leaflet was last revised in September 2017
To request a copy of this leaflet in Braille, large print or audio
format, please contact the marketing authorisation holder at
the address (or telephone, fax, email) above.

V4 27-09-17 D2


220 mm

140 mm

Tell your doctor or pharmacist if you notice any of the
following and they worry you:
• upset stomach
• diarrhoea
• nausea
• vomiting
• black hairy tongue
• thrush (a yeast infection of the vagina, mouth or skin folds)
• jaundice (yellow colouring of the skin and whites of the
• hepatitis
• sore throats, infections or fever (may be caused by low
white blood cells)
• anaemia (lack of energy or tiredness)
• kidney problems, which might cause blood in the urine or
reduced amounts of urine
• convulsions, especially with high doses or in patients with
severe kidney problems
• pins and needles or numbness
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or
nurse. This includes any possible side effects not listed in
this leaflet. You can also report side effects directly via the
Yellow Card Scheme at: By
reporting side effects you can help provide more information
on the safety of this medicine.


Patients with kidney and liver problems
• If you have kidney problems the dose might be changed
by your doctor.
• Dosage might be changed by your doctor if you have liver
problems along with kidney problem.
If you take more tablets than you should
If you accidently take too many tablets, tell your doctor
immediately or contact your nearest Hospital Casualty/
Accident and Emergency Department even if there are no
signs of discomfort. Take your medicine in its original packaging
with you in order to enable the doctor to identify your
medication easily.
If you forget to take the tablets
If you forget to take a dose, take it as soon as you remember,
however, if it is almost time for your next dose, skip the missed
dose and then take your next dose when it is due.
If you stop taking this medicine
Take all the tablets that have been prescribed for you, even
if you start to feel better. Your symptoms may start to improve
before the condition is completely treated. If you stop taking
the tablets your condition may re-occur or get worse.
If you have any further questions on the use of this medicine,
ask your doctor or pharmacist.

eSign & Date:

eSign & Date:

Approved for
eSign & Date:

Final approval
by MA Holder
eSign & Date

Packing Site
eSign & Date:

Kaypee Design

Artist’s artwork version
with/without date
MA Number (s)
MA Holder

V1 16-08-2014 D0, V2 23-06-2015 D0, V3 29-06-2015 D0, V4 27-09-17 D2

PL 17907/0033

Bristol Laboratories Ltd.

Packaging site
Reason for revision

Text and size changed

220 mm
140 mm

Fonts & size

Arial narrow Text size-7.8, Sub headings size-9, Main Heading size 10

Pantone colours


Manufacturing site

Manufacturing site code if applicable:

IMPORTANT: Artwork, text and content must not be reset, remade, amended or altered.
The only exceptions to this are: bleeds, chokes, spreads or other print related adjustments
required for reproduction by the supplier. We must receive a copy of any 3rd Party Supplier’s
Proof before approval to print will be granted.
To include Manufacturing site’s sub-versions of MA holder’s regulatory artwork version
(Due to frequent machine shift and packaging running on more than one kind of machine)

+ Expand Transcript

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.