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PERSANTIN RETARD 200MG MODIFIED RELEASE HARD CAPSULES
Active substance(s): DIPYRIDAMOLE / DIPYRIDAMOLE / DIPYRIDAMOLE
Persantin Retard 200mg
Modified Release Hard
Read all of this leaflet carefully
before you start taking this medicine.
Keep this leaflet. You may need to
read it again.
If you have any further questions, ask
your doctor or pharmacist.
This medicine has been prescribed for
you. Do not pass it on to others. It may
harm them, even if their symptoms are
the same as yours.
If any of the side effects gets
troublesome or serious, or if you notice
any side effects not listed in this
leaflet, please tell your doctor or
The name of your medicine is Persantin
Retard 200mg Modified Release Hard
Capsules, but it will be referred as
Persantin Retard throughout this leaflet.
In this leaflet:
1. What Persantin Retard is and what it is
2. Before you take Persantin Retard
3. How to take Persantin Retard
4. Possible side effects
5. How to store Persantin Retard
6. Further information
1. WHAT PERSANTIN RETARD IS
AND WHAT IT IS USED FOR
The name of your medicine is Persantin
Retard. It contains a medicine called
Dipyridamole. This belongs to a group of
medicines called ‘anti-thrombotic agents’,
which are used to help stop blood clots
Persantin Retard is used:
To help stop blood clots which may
occur if you have had your heart
In people who have had a stroke
caused by a blood clot in the brain.
This medicine reduces the risk of
having another stroke.
2. BEFORE YOU TAKE
Do not take Persantin Retard if you
are allergic (hypersensitive) to:
Any of the other ingredients of
Persantin Retard (see section 6:
Take special care with Persantin
Check with your doctor or pharmacist
before taking your medicine if:
You have angina or other heart
problems (including heart valve or
circulation problems) or have had a
recent heart attack
You have myasthenia gravis (a rare
You have any bleeding problems
You are pregnant or planning to
become pregnant or are breastfeeding
If you are not sure if any of the above
apply to you, talk to your doctor or
pharmacist before taking Persantin
Taking other medicines
Please tell your doctor or pharmacist if you
are taking or have recently taken any
other medicines, including medicines
obtained without a prescription. This
includes herbal medicines. This is
because Persantin Retard can affect the
way some other medicines work. Also
some other medicines can affect the way
Persantin Retard works.
In particular, tell your doctor or pharmacist
if you are taking any of the following
Medicines for high blood pressure
Medicines for muscle weakness such
as something called a ‘cholinesterase
Aspirin (or planning to take aspirin for
Adenosine injection - used for heart
problems or tests on the heart
Warfarin or other medicines to stop
blood clots forming. If so, tell them at
your next visit to the anticoagulant
clinic that you are now taking
If you are having heart tests
Persantin Retard contains dipyridamole.
Dipyridamole is also sometimes given as
an injection during tests to see if the heart
is working properly (also called
‘myocardial imaging’). This means that the
test and your medicine may contain the
same substance. If you are going to have
an injection of dipyridamole, tell the doctor
that you are taking Persantin Retard.
Pregnancy and breast-feeding
Tell your doctor if you are pregnant or
planning to get pregnant.
Tell your doctor if you are breastfeeding as Persantin Retard should
only be used during breast-feeding if
your doctor considers it essential.
Driving and using machines
You may feel dizzy while taking Persantin
Retard. If this happens do not drive or use
any tools or machines.
3. HOW TO TAKE PERSANTIN
Always take this medicine exactly as your
doctor has told you. You should check
with your doctor or pharmacist if you are
The usual dose is:
One capsule twice a day
Usually one in the morning and one in
It is best to take it with food
Swallow the capsule whole
Do not crush or chew it
Do not give to children.
If you take more Persantin Retard
than you should
If you take more of this medicine than you
should, talk to a doctor or go to a hospital
straight away. Take the medicine pack
with you, even if there are no capsules
If you forget to take Persantin Retard
If you forget a dose, take it as soon as
you remember it
However, if it is time for the next dose,
skip the missed dose
Do not take a double dose to make up
for the forgotten dose
If you have any further questions on the
use of this product, ask your doctor or
4. POSSIBLE SIDE EFFECTS
Like all medicines Persantin Retard can
cause side effects, although not
everybody gets them.
If you have an allergic reaction, stop
taking your medicine and see a doctor
straight away. The signs may include
feeling breathless, runny nose, severe
rash with itching, swelling and swelling
around the eyes.
Other side effects that have been reported
for Persantin Retard are described below.
They are listed as either very common,
common, or not known.
Very common (affects more than 1 in 10
Feeling sick (nausea)
Common (affects less than 1 in 10
people but more than 1 in 100 people)
Being sick (vomiting)
Worsening of the symptoms of heart
disease such as chest pain and
shortness of breath
Lowering of blood pressure or
increased heart rate
A blood problem called
‘thrombocytopenia’ which can cause
bruising and prolonged bleeding from
wounds, including during or after
In people who have gallstones, the
dipyridamole in this medicine can be
absorbed into the gallstones.
Reporting of side effects
If you get any side effects, talk to your
doctor, pharmacist or nurse. This includes
any possible side effects not listed in this
leaflet. You can also report side effects
directly via the Yellow Card Scheme at:
By reporting side effects, you can help
provide more information on the safety of
5. HOW TO STORE PERSANTIN
Keep out of the sight and reach of
Do not store above 30 C.
Keep the bottle tightly closed in order to
protect from moisture.
Do not take the capsules after the expiry
date which is stated on the carton and
bottle label after ‘Exp’. The expiry date
refers to the last day of that month.
Discard any capsules remaining 6 weeks
after first opening.
If the capsules become discoloured or
show any signs of deterioration, seek the
advice of your pharmacist.
Medicines should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of medicines
that are no longer required. These
measures will help to protect the
6. FURTHER INFORMATION
What Persantin Retard contains
The active ingredient in Persantin Retard
Each modified release capsule contains
Persantin Retard is a modified release
capsule which releases the active
substance slowly in your body over a
number of hours.
The other ingredients are: tartaric acid,
povidone, eudragit, talc, gum arabic,
hypromellose, hypromellose phthalate,
triacetin, dimethicone, stearic palmitic
acid, gelatin, titanium dioxide, red iron
oxide and yellow iron oxide.
What Persantin Retard looks like and
contents of the pack
Persantin Retard capsules are red and
orange hard gelatin modified release
capsules containing microgranules.
Persantin Retard capsules are available in
a white plastic bottle with a child-resistant
screw cap and a dessicant.
They are available in packs of 60
Manufactured by: Boehringer Ingelheim
Pharma GmbH & Co. KG, Birkendorfer
Strasse 65, D-88397 Biberach an der
Procured from within the EU and
repackaged by the Product Licence
holder: B&S Healthcare, Unit 4,
Bradfield Road, Ruislip, Middlesex,
HA4 0NU, UK.
Persantin Retard 200mg Modified
Release Hard Capsules;
Leaflet Date: 15.08.2016
Persentin Retard is a registered trademark
of Boehringer Ingelheim group of
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.