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Active substance(s): DIPYRIDAMOLE

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Package leaflet: Information for the user:

Persantin® Retard 200 mg Capsules
Your medicine is known by the above name but will be
referred to in this leaflet as PERSANTIN Retard.
Read all of this leaflet carefully before you
start taking this medicine.
• Keep this leaflet. You may need to read it
• If you have any further questions, ask
your doctor or pharmacist.
• This medicine has been prescribed for
you. Do not pass it on to others. It may
harm them, even if their symptoms are
the same as yours.
• If any of the side effects gets troublesome
or serious, or if you notice any side
effects not listed in this leaflet, please
tell your doctor or pharmacist.
In this leaflet:
1. What PERSANTIN Retard is and what it
is used for
2. Before you take PERSANTIN Retard
3. How to take PERSANTIN Retard
4. Possible side effects
5. How to store PERSANTIN Retard
6. Further information

The name of your medicine is PERSANTIN
Retard. It contains a medicine called
Dipyridamole. This belongs to a group of
medicines called ‘anti-thrombotic agents’,
which are used to help stop blood clots
PERSANTIN Retard is used:
• To help stop blood clots which may
occur if you have had your heart valves
• In people who have had a stroke
caused by a blood clot in the brain. This
medicine reduces the risk of having
another stroke.

Do not take PERSANTIN Retard if you are
allergic (hypersensitive) to:
• Dipyridamole
• Any of the other ingredients of
PERSANTIN Retard (see section 6:
Further Information)
Take special care with PERSANTIN Retard
Check with your doctor or pharmacist
before taking your medicine if:
• You have angina or other heart problems
(including heart valve or circulation
problems) or have had a recent heart
• You have myasthenia gravis (a rare
muscle problem)
• You have any bleeding problems
• You are pregnant or planning to
become pregnant or are breast-feeding
If you are not sure if any of the above
apply to you, talk to your doctor or
pharmacist before taking PERSANTIN

Taking other medicines
Please tell your doctor or pharmacist if you
are taking or have recently taken any other
medicines, including medicines obtained
without a prescription. This includes
herbal medicines. This is because
PERSANTIN Retard can affect the way
some other medicines work. Also some
other medicines can affect the way
PERSANTIN Retard works.
In particular, tell your doctor or pharmacist
if you are taking any of the following
• Medicines for high blood pressure
• Medicines for muscle weakness such as
something called a ‘cholinesterase
• Aspirin (or planning to take aspirin for
any condition)
• Adenosine injection - used for heart
problems or tests on the heart
• Warfarin or other medicines to stop blood
clots forming. If so, tell them at your next
visit to the anticoagulant clinic that you
are now taking PERSANTIN Retard
If you are having heart tests
PERSANTIN Retard contains dipyridamole.
Dipyridamole is also sometimes given as an
injection during tests to see if the heart is
working properly (also called ‘myocardial
imaging’). This means that the test and
your medicine may contain the same
substance. If you are going to have an
injection of dipyridamole, tell the doctor
that you are taking PERSANTIN Retard.
Pregnancy and breast-feeding
• Tell your doctor if you are pregnant or
planning to get pregnant.
• Tell your doctor if you are breast-feeding
as PERSANTIN Retard should only be
used during breast-feeding if your doctor
considers it essential.
Driving and using machines
You may feel dizzy while taking PERSANTIN
Retard. If this happens do not drive or use
any tools or machines.

Always take this medicine exactly as your
doctor has told you. You should check
with your doctor or pharmacist if you are
not sure.
The usual dose is:
• One capsule twice a day
• Usually one in the morning and one in
the evening
• It is best to take it with food
• Swallow the capsule whole
• Do not crush or chew it
Do not give to children.
If you take more PERSANTIN Retard than
you should
If you take more of this medicine than you
should, talk to a doctor or go to a hospital
straight away. Take the medicine pack with
you, even if there are no capsules left.

If you forget to take PERSANTIN Retard
• If you forget a dose, take it as soon as
you remember it
• However, if it is time for the next dose,
skip the missed dose
• Do not take a double dose to make up
for the forgotten dose
If you have any further questions on the
use of this product, ask your doctor or

Like all medicines PERSANTIN Retard can
cause side effects, although not everybody
gets them.
Allergic reactions
If you have an allergic reaction, stop taking
your medicine and see a doctor straight
away. The signs may include feeling
breathless, runny nose, severe rash with
itching, swelling and swelling around the
Other side effects that have been reported
for PERSANTIN Retard are described
below. They are listed as either very
common, common, or not known.
Very common (affects more than 1 in 10
• Headache
• Feeling dizzy
• Feeling sick (nausea)
• Diarrhoea
Common (affects less than 1 in 10 people
but more than 1 in 100 people)
• Muscle pain
• Being sick (vomiting)
• Worsening of the symptoms of heart
disease such as chest pain and shortness
of breath
Not Known
• Hot flushes
• Lowering of blood pressure or increased
heart rate
• A blood problem called ‘thrombocytopenia’
which can cause bruising and
prolonged bleeding from wounds,
including during or after surgery
In people who have gallstones, the
dipyridamole in this medicine can be
absorbed into the gallstones.
Reporting of side effects
If you get any side effects, talk to your
doctor, pharmacist or nurse. This includes
any possible side effects not listed in this
leaflet. You can also report side effects
directly (see details below). By reporting
side effects you can help provide more
information on the safety of this medicine.
United Kingdom
Yellow Card Scheme

Keep out of the sight and reach of
Do not store above 30°C.
Keep the bottle tightly closed. Store in the
original package in order to protect from
Do not use PERSANTIN Retard after the
expiry date which is stated on the carton
and container label after EXP. The expiry
date refers to the last day of that month.
Do not open the bottle until you are
ready to start taking the capsules. If you
have any capsules left after six weeks,
these should not be taken.
Medicines should not be disposed of via
wastewater or household waste. Ask your
pharmacist how to dispose of medicines
no longer required. These measures will
help protect the environment.

What PERSANTIN Retard contains
The active substance is dipyridamole. Each
modified release capsule contains
dipyridamole 200 mg. PERSANTIN Retard
is a modified release capsule which
releases the active substance slowly in
your body over a number of hours.
The other ingredients in PERSANTIN
Retard are: hypromellose, tartaric acid,
acacia, povidone, methacrylic acidmethylmethacrylate
copolymer (1:2), hypromellose phthalate, Dimethicone
350, triacetin, talc and stearic acid.
The capsule shells contain gelatin,
titanium dioxide (E171), red iron oxide
(E172) and yellow iron oxide (E172).
What PERSANTIN Retard looks like and
contents of the pack
Hard gelatin capsules consisting of a red cap and an
orange body.
PERSANTIN Retard is available as a 60 pack size.
Boehringer Ingelheim Pharma GmbH
& Co. KG
Birkendorfer Strasse 65
88397 Biberach an der Riss


Procured from within the EU and repackaged by PL holder
PilsCo Ltd, 10-16 Colvilles Place, East Kilbride, G75 0SN.
PL 39467/0272 Persantin Retard 200 mg Capsules
This leaflet was revised in 25.10.2016
Persantin® is a registered trademark of Boehringer
Ingelheim Pharma GmbH & Co. KG.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.