Skip to Content

OXYTETRACYCLINE TABLETS BP 250MG

Active substance(s): OXYTETRACYCLINE DIHYDRATE

View full screen / Print PDF » Download PDF ⇩
Transcript
• have had kidney or liver problems for a long time
• have systemic lupus erythematosus (SLE), a condition
characterised by a rash (especially on the face), hair
loss, fever, malaise and joint pain

Index
1 What Oxytetracycline tablets
are and what they are used for
2 Before you take
3 How to take
4 Possible side effects
5 How to store
6 Further information

Taking other medicines

1 What Oxytetracycline tablets are and
what they are used for

Oxytetracycline belongs to a group of medicines called
tetracycline antibiotics. It is also known as a broadspectrum antibiotic and may be used to treat a wide
range of infections caused by bacteria. These include:
• lung infections such as pneumonia, bronchitis or
whooping cough
• urinary tract infections
• sexually transmitted diseases such as chlamydia,
gonorrhoea or syphilis
• skin infections such as acne
• infections of the eye such as conjunctivitis
• rickettsial infections such as Q fever or tick fever
(severe headache, rash, high fever)
• other infections including brucellosis (headache,
sickness, fever, swollen lymph nodes), psittacosis
(headache, nose bleeds, shivering, fever), plague
(painful swelling of the lymph nodes), cholera (severe
sickness and diahorrea)
• leptospirosis (fever causing jaundice or meningitis),
gas-gangrene and tetanus (lock jaw).

2 Before you take

Do not take Oxytetracycline tablets and tell your
doctor if you:

• are allergic (hypersensitive) to oxytetracycline, other
similar antibiotics (such as minocycline or doxycycline)
or any other ingredient in the tablet (see section 6).
The tablet contains sunset yellow (E110) which may
cause allergic reactions

83.6mm

Pharmacode
Position

Read all of this leaflet carefully before
you start taking this medicine.
• Keep this leaflet. You may need to read it
again.
• If you have any further questions, ask your
doctor or pharmacist.
• This medicine has been prescribed for
you. Do not pass it on to others. It may
harm them, even if their symptoms are the
same as yours.

Do not give to a child under 12 years old.
Take special care with Oxytetracycline tablets and tell
your doctor if you:
• suffer from myasthenia gravis, a condition
characterised by muscle weakness, difficulty chewing
and swallowing and slurred speech
• have reduced kidney or liver function.
Please tell your doctor or pharmacist if you are taking
or have recently taken any other medicines, including
medicines obtained without a prescription. Especially:
• penicillins such as amoxicillin (to treat infections)
• vitamin A
• retinoids such as acitretin, isotretinoin and tretinoin
(to treat acne)
• oral contraceptives (the pill). Oxytetracycline tablets
may make the oral contraceptive pill less effective. You
should use additional contraceptive precautions whilst
taking Oxytetracycline and for 7 days after stopping
• anticoagulants e.g. warfarin (to stop the blood
clotting)
• diuretics (‘water tablets’ such as furosemide)
• kaolin-pectin and bismuth subsalicylate (to treat
diarrhoea)
• medicines to treat diabetes such as insulin,
glibenclamide or gliclazide
• methoxyflurane (an anaesthetic), if you need an
operation, tell your doctor or dentist you are taking
Oxytetracycline
• medicines such as antacids or other medicines
containing aluminium, calcium, iron, magnesium,
bismuth or zinc salts. Do not take at the same
time as Oxytetracycline tablets, as absorption of
Oxytetracycline may be reduced. Allow 2 to 3 hours
between taking antacids and oxytetracycline.

CL

210mm +/- 0.5mm to centre line of next eye mark

65mm

Oxytetracycline tablets 250mg

Pregnancy and breastfeeding

If you are pregnant, planning to become pregnant or are
breast feeding ask your doctor or pharmacist for advice
before taking any medicine as Oxytetracycline should
not be taken as it could harm the baby.

Tests

During long term treatment blood, kidney and liver tests
will be carried out.

Taking with food or milk

Do not take the tablets at the same time as milk or food,
as they can make the medicine less effective.

Continued top of next column
50326658

15mm

15mm

3 How to take

Always take Oxytetracycline tablets exactly as your doctor
has told you. If you are not sure, check with your doctor or
pharmacist.
Swallow the tablets one hour before or two hours after
meals, with a glass of water. Swallow the tablets when
standing or sitting down and do not take them immediately
before going to bed. Avoid exposure to natural or artificial
sunlight as skin reactions may occur.
The usual doses are for at least 10 days unless otherwise
directed by your doctor:
• Adults, Elderly and Children 12 years or over:
General infections: 1 tablet (250mg) every 6 hours,
you may be given 2 tablets (500mg) initially. For severe
infections your doctor may increase your dosage to 500mg
(2 tablets) every 6 hours.
Specific infections:
Skin infections: 1-2 tablets (250-500mg) daily either as a
single dose or in divided doses for three months.
Brucellosis: 2 tablets (500mg) four times a day with
streptomycin.
Sexually transmitted diseases: 2 tablets (500mg) four
times a day for between 7 and 30 days depending on your
condition.
• Children under 12 years old:
Oxytetracycline tablets are not recommended for
use in children under 12 years of age as it can cause
permanent discolouration of tooth enamel and affect bone
development.

If you take more than you should

If you (or someone else) swallow a lot of tablets at the same
time, or you think a child may have swallowed any contact
your nearest hospital casualty department or tell your doctor
immediately.

If you forget to take the tablets

Do not take a double dose to make up for a forgotten dose. If
you forget to take a dose take it as soon as you remember it
and then take the next dose at the right time.

If you stop taking the tablets

Do not stop treatment early as your infection may return if
you do not finish the course of tablets.

4 Possible side effects

Like all medicines, Oxytetracycline tablets can cause side
effects, although not everybody gets them.

5 How to store

Keep out of the reach and sight of children.
Store below 25°C in a dry place and in the original packaging.
Do not use Oxytetracycline tablets after the expiry date stated
on the label/carton/bottle. The expiry date refers to the last
day of that month.
Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help to
protect the environment.

6 Further information

What Oxytetracycline tablets contain

• The active substance (the ingredient that makes the tablets
work) is oxytetracycline dihydrate.
• The other ingredients in the tablet are magnesium stearate,
maize starch, hydroxypropylcellulose (E463), colloidal silica,
sodium lauryl sulphate.
• The tablet coating contains propylene glycol,sunset yellow
(E110), quinoline yellow (E104), titanium dioxide (E171),
methylhydroxypropylcellulose (E464), purified talc (E553).

What Oxytetracycline tablets look like and
contents of the pack
Oxytetracycline tablets are yellow, circular,
biconvex, film coated tablets which come in
one strength. Each tablet contains 250mg of
the active ingredient.
Pack size is 28 tablets

Marketing Authorisation Holder and
manufacturer
Actavis, Barnstaple, EX32 8NS, UK

This leaflet was last revised in February 2010.

65mm

Tell your doctor if the following side effects occur:
• Feeling or being sick, diarrhoea, stomach upsets, loss
of appetite, discolouration of tooth enamel, difficulty
swallowing, swelling or ulceration of the gullet.
Pseudomembranous colitis (watery diarrhoea, fever and
cramps)
• Inflammation of the pancreas (pancreatitis, causing pain in
the abdomen or back, feeling sick and fever)
Continued top of next column
50326658

If you notice any side effects, they get worse, or if you notice
any not listed, please tell your doctor or pharmacist.

Pharmacode
Position

Stop taking the tablets immediately and seek urgent
medical advice if the following occur:
• symptoms of an allergic reaction: skin rashes which may be
itchy, swelling of the face and tongue. Fever and chest pain
(symptoms of inflammation of the membrane around the
heart) or breathing difficulties and collapse (anaphylaxis)
• symptoms of raised pressure in the skull: headache, visual
problems including blurred vision, “blind” spots, double
vision
• sensitivity to sunlight or artificial light such as sun-bed
(symptoms such as tingling, burning or redness of the skin).

• Changes in the numbers and types of your blood cells. If
you notice increased bruising, nosebleeds, sore throats,
infections, excessive tiredness, breathlessness on exertion or
abnormal paleness of the skin, you should tell your doctor
who may want you to have a blood test
• Redness or colour change of the skin, flaky skin, thrush
or irritation around your bottom and genital area. If you
already suffer from SLE (systemic lupus erythematosus)
Oxytetracycline tablets may make your condition worse
• Changes in liver or kidney function (tiredness, pain in the
abdomen or back, difficulty passing urine) jaundice (yellow
skin or eyes).

Actavis, Barnstaple, EX32 8NS, UK

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Hide