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Active substance(s): ACETYLSALICYLIC ACID

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Nu-Seals 75
aspirin (acetylsalicylic acid)
Read all of this leaflet carefully before you start taking this medicine
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you. Do not pass it on to others. It
may harm them, even if their symptoms are the same as yours.
• If any of the side effects gets serious, or if you notice any side effects not
listed in this leaflet please tell your doctor or pharmacist.
The information in this leaflet has been divided into the following
1. What Nu-Seals 75 is and what it is taken for
2. Check before you take Nu-Seals 75
3. How to take Nu-Seals 75
4. Possible side effects
5. How to store Nu-Seals 75
6. Further information

1. What Nu-Seals 75 is and what it is taken for
Nu-Seals 75 contains aspirin. Aspirin is used:
• to prevent recurrence of heart attacks or strokes by thinning the blood. If
someone who has previously had a heart attack or stroke takes Nu-Seals
75 regularly, it reduces the risk of a blood clot occurring in the heart or
brain. This can prevent further heart attacks or strokes.
If you take aspirin in high doses or over a long period of time, it can
irritate your stomach lining. To prevent stomach irritation, these tablets
have a special coating (called enteric) so that the aspirin is not released
until it has passed through the stomach.
Aspirin is released slowly from these tablets, so Nu-Seals 75 is not suitable
for the short-term relief of pain, such as headaches or toothache.

2. Check before you take Nu-Seals 75
Do not take Nu-Seals 75:

if you are allergic to aspirin or if you are allergic to any of the ingredients in
Nu-Seals 75 (see Section 6 Further information)
if you have ever had the problem of your blood not clotting properly
if you have ever had an ulcer in your stomach or small intestine.

Take special care with Nu-Seals 75
Before you take Nu-Seals 75 tell your doctor if you:
• think you may be dehydrated (you may feel thirsty with a dry mouth)
• have trouble with your kidneys or liver
• have high blood pressure
• if you are asthmatic, aspirin may induce an asthma attack
When given to children aspirin may cause Reye’s syndrome. Reye’s
syndrome is a very rare disease, which can be fatal. For this reason,
aspirin should not be given to children aged under 16 years, unless on
the advice of a doctor.
If any of the above applies to you, or if you are not sure, speak to your doctor
or pharmacist before you take Nu-Seals 75.
Taking other medicines
The effect of treatment may be influenced if aspirin is taken at the same time as
some other medicines for:
• thinning of the blood/prevention of clots (e.g. warfarin)
• organ rejection after transplantation (e.g. ciclosporin, tacrolimus)
• high blood pressure (e.g. diuretics and ACE-inhibitors)
• pain and inflammation (e.g. anti-inflammatory medicines such as ibuprofen, or
• gout (e.g. probenecid)
• cancer or rheumatoid arthritis (e.g. methotrexate)

insulin or any other drug to treat diabetes
corticosteroids (used as hormone replacement therapy when the adrenal
glands or pituitary gland have been destroyed or removed, or to treat
inflammation, including rheumatic diseases and inflammation of the
phenytoin or sodium valproate (used to control epilepsy)
sulphonamides (a type of antibiotic) such as sulfamethoxazole.
medicines such as acetazolamide used to treat glaucoma
antacids (indigestion medicine). Do not take antacids just before or after
taking Nu-Seals 75 as they may cause the aspirin to be released too soon.

Before using aspirin you should inform a healthcare professional about the medicines
you are taking. If you are using aspirin regularly you should seek advice before taking
any other medicine (including other medicines you may have bought).

Pregnancy and breast-feeding
Pregnant women should not take aspirin during pregnancy unless advised by
their doctor. Regular or high dose aspirin therapy during late pregnancy can
cause serious complications in the mother or baby.

Do not take Nu-Seals 75 if you are breast-feeding because some of the
aspirin may be in your breast milk, and could harm your baby.
Ask your doctor or pharmacist for advice before taking any medicine.

3. How to take Nu-Seals 75
Always take Nu-Seals 75 exactly as your doctor has told you to. You should
check with your doctor or pharmacist if you are not sure.

Prevention of heart attacks, angina or mini-strokes:
For your first dose your doctor will tell you to chew two 75mg
tablets. Chewing the tablets will help the aspirin
start to work quickly.
After this first dose The usual dose is one or two 75 mg tablets each
day. Sometimes your doctor may tell you to take a
higher dose.

Apart from the first dose of Nu-Seals, swallow the tablets whole with water.
Do not cut, crush or chew them as this will damage the special coating. If the
coating is damaged the tablets are more likely to irritate your stomach.
If you may be taking this medicine for a long time, you should talk to your
doctor about it.
What to do if you take more Nu-Seals 75 than you should
If you (or someone else) accidentally take too many tablets, you should tell
your doctor at once or contact the nearest casualty department. Show any left
over medicines or the empty packet to the doctor.
If you forget to take Nu-Seals 75
Do not worry. If you miss a dose, wait until it is time for your next dose, then
go on as normal. DO NOT take a double dose.
If you have any further questions on the use of this product, ask your doctor or

4. Possible Side Effects
Like all medicines, Nu-Seals 75 can cause side effects, although not everyone
gets them. The more common side effects of aspirin include:
• hypersensitivity (which may mean you have skin rashes or itching, or
wheezing or coughing or difficulty breathing)
• nausea and vomiting
• ringing in your ears
• pain or discomfort in your stomach or lower chest after eating.

Aspirin may sometimes cause asthma or bronchospasm (narrowing of the
airways that causes wheezing or difficulty breathing).
Aspirin may cause bleeding, and you must tell your doctor if you experience
any unusual bleeding.
Rarely, you may suffer more serious side effects, tell your doctor immediately
if you get any of the following:
• blood in your vomit
• blood in your urine
• bruising with purple spots
• coughing up blood (however small the amount)
• any swellings
• black stools
• kidney stones (which can cause severe stomach or back pains).

If any of the side effects gets worse, or if you notice any side effects not listed
in this leaflet, please tell your doctor.

5. How to store Nu-Seals 75
Keep out of the reach and sight of children.
Do not use Nu-Seals 75 after the use before date which is stated on the
carton and blister.
Do not store above 25°C. Do not take Nu-Seals 75 if you notice the
appearance has changed in any way.

Medicines should not be disposed of via wastewater or household waste. Ask
your pharmacist on how to dispose of medicines no longer required. These
measures will help protect the environment.

6. Further information
What Nu-Seals 75 contains
The active ingredient in this medicine is aspirin (acetylsalicylic acid). Each
tablet of Nu-Seals 75 contains 75 milligrams (mg) of aspirin.
The other ingredients are maize starch, hypromellose, talc, methacrylic acidethyl acrylate (1:1) copolymer dispersion 30 percent, polyethylene glycol
3350, propylene glycol, benzyl alcohol, emulsion silicone. Printing ink
containing shellac, iron oxide (E172), isopropyl alcohol, n-butyl alcohol,
propylene glycol, ammonium hydroxide (E527) and simeticone.
What Nu-Seals 75 looks like and contents of the pack

Nu-Seals 75 is a white tablet, with 75 on it in red. Nu-Seals 75 comes in
boxes of 56 tablets.
Marketing Authorisation Holder and Manufacturer
The product licence holder is: Alliance Pharmaceuticals Ltd, Avonbridge
House, Chippenham, Wiltshire, SN15 2BB, UK.
Nu-Seals 75 is manufactured by Chanelle Medical, Loughrea, Co Galway,
The information in this leaflet applies only to Nu-Seals 75. If you have any
questions or you are not sure about anything, ask your doctor or a
This leaflet was last approved : October 2011
Nu-Seals is a trademark of Alliance Pharmaceuticals Limited.
Alliance, Alliance Pharmaceuticals and associated devices are registered
© Alliance Pharmaceuticals Limited, 2011

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.