NARATRIPTAN HYDROCHLORIDE 2.5 MG TABLETS
Active substance(s): NARATRIPTAN HYDROCHLORIDE / NARATRIPTAN HYDROCHLORIDE / NARATRIPTAN HYDROCHLORIDE
NARAMIG® 2.5MG TABLETS
If you have kidney or liver disease
With other migraine medicines, including those
which contain ergotamine, or with similar medicines
such as methysergide, or with other 5-HT1 receptor
agonists, such as sumatriptan.
Your medicine is available as Naramig 2.5mg Tablets, but will
be referred to as Naramig throughout this leaflet.
If any of these apply to you:
Tell your doctor, and don’t take Naramig.
Read all of this leaflet carefully before you
start taking this medicine because it contains
important information for you.
Warnings and precautions
Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or
This medicine has been prescribed for you only. Do not
pass it on to others. It may harm them, even if their
signs of illness are the same as yours.
If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects not
listed in this leaflet. See section 4.
What is in this leaflet
What Naramig is and what it is used for
What you need to know before you take Naramig
How to take Naramig
Possible side effects
How to store Naramig
Contents of the pack and other information
1. What Naramig is and what it is used for
Naramig tablets contain naratriptan (hydrochloride), which
belongs to a group of medicines called triptans (also known
as 5-HT1 receptor agonists).
Naramig tablets are used to treat migraine.
Migraine symptoms may be caused by the temporary
widening of blood vessels in the head. Naramig tablets are
believed to reduce the widening of these blood vessels. This
in turn helps to take away the headache and relieve other
symptoms of a migraine attack, such as feeling or being sick
(nausea or vomiting) and sensitivity to light and sound.
2. What you need to know before you take
Do not take Naramig:
If you are allergic to naratriptan, or any of the other
ingredients of this medicine (listed in section 6)
If you have a heart problem such as heart failure or
chest pains (angina), or have already had a heart attack
If you have circulation problems in your legs that
cause cramp-like pains when you walk (peripheral
If you have had a stroke or a mini-stroke (also called
a transient ischaemic attack or TIA)
If you have high blood pressure. You may be able to
take Naramig if your high blood pressure is mild and is
Talk to your doctor or pharmacist before taking Naramig.
If you have any extra risk factors
If you are a heavy smoker or are using nicotine
replacement therapy, and especially
If you are a man over 40, or
If you are a woman who has been through the
In very rare cases, people have developed serious heart
conditions after taking Naramig, even though they had no
signs of heart disease before.
If any of the points in the list applies to you, it could mean
you have a greater risk of developing heart disease – so:
Tell your doctor so that your heart function can be
checked before Naramig is prescribed for you.
If you are allergic to antibiotics called sulphonamides
If so, you may also be allergic to Naramig. If you know you
are allergic to an antibiotic but you are not sure whether it is
Tell your doctor or pharmacist before taking
If you take Naramig frequently
Taking Naramig too often may make your headaches worse.
Tell your doctor if this applies to you. He or she may
recommend you stop taking Naramig.
If you feel pain or tightness in your chest after you
These effects may be intense but they usually pass quickly.
If they don’t pass quickly, or they become severe:
Get medical help immediately. Section 4 of this
leaflet has more information about these possible side
Not for older people or children under 18
Naramig is not recommended for people aged over 65 or
for children under the age of 18.
Other medicines and Naramig
Tell your doctor if you’re taking, have recently taken or
might take any other medicines.
Some medicines must not be taken with Naramig and others
may cause adverse effects if they’re taken with Naramig. You
must tell your doctor if you are taking:
any medicines for your migraine which contain any
triptan/5-HT1 agonist (such as sumatriptan or
zolmitriptan). Don’t take Naramig at the same time as
these medicines. Stop taking these medicines at least 24
hours before taking Naramig.
ergotamine also used to treat migraine or similar
medicines such as methysergide. Don’t take Naramig
at the same time as these medicines. Stop taking these
medicines at least 24 hours before taking Naramig.
any antidepressants classed as selective serotonin
reuptake inhibitors (SSRIs), such as citalopram,
fluoxetine or paroxetine, or serotonin noradrenaline
reuptake inhibitors (SNRIs) such as venlafaxine. If you
are not sure, talk to your doctor or pharmacist.
St John’s Wort (Hypericum perforatum). Using herbal
remedies that contain St John’s Wort while you are
taking Naramig may make side effects more likely.
Pregnancy and breast-feeding
If you are pregnant, think you may be pregnant or
are planning to have a baby ask your doctor for
advice before taking this medicine. There is only limited
information about the safety of Naramig for pregnant
women, though up till now there is no evidence of any
increased risk of birth defects. Your doctor may
recommend that you do not take Naramig while you are
Don’t breast-feed your baby for 24 hours after
taking Naramig. If you express any breast milk during
this time, discard the milk and don’t give it to your
Driving and using machines
Either the symptoms of migraine or your medicine may
make you drowsy. If you are affected, don’t drive or
Naramig contains lactose
Naramig tablets contain a small amount of a sugar called
If you have an intolerance to lactose or any other sugars:
Ask your doctor for advice about taking Naramig.
3. How to take Naramig
Only take Naramig after your migraine headache
begins. Don’t take Naramig to try to prevent an attack.
Always take this medicine exactly as your doctor has told
you. Check with your doctor or pharmacist if you are not
How much to take
The usual dose for adults aged 18 to 65 is one
Naramig 2.5mg tablet, swallowed whole with water.
Naramig is not recommended for children under 18 and
adults over 65.
Page 1 of 2
When to take Naramig
It’s best to take Naramig as soon as you feel a
migraine coming on, although it can be taken at any
time during an attack.
If your symptoms start to come back
You can take a second Naramig tablet after 4 hours,
unless you have kidney or liver damage.
If you have kidney or liver damage don’t take more
than one tablet in 24 hours.
No one should take more than two tablets in 24
If the first tablet has no effect
Don’t take a second tablet for the same attack.
If Naramig doesn’t give you any relief:
Ask your doctor or pharmacist for advice.
If you take more Naramig than you should
Common: may affect up to 1 in 10 people
Feeling sick (nausea) or being sick (vomiting),
although this may be due to the migraine itself.
Tiredness, drowsiness or sleepiness (somnolence), or
generally feeling unwell.
Dizziness, tingling feelings or getting hot flushes.
If you get any of these effects:
Tell your doctor or pharmacist.
Uncommon: may affect up to 1 in 100 people
Visual disturbances (although these may be due to
the migraine attack itself).
Slight increase in blood pressure which may occur
up to 12 hours after taking Naramig.
If you get any of these effects:
Tell your doctor or pharmacist.
Very rare: may affect up to 1 in 10,000 people
Don’t take more than two Naramig tablets in 24
Taking too much Naramig could make you ill. If you have
taken more than two tablets in 24 hours:
Contact your doctor for advice.
Heart problems, including chest pains (angina) and
Poor blood circulation to the arms and legs, causing
pain and discomfort.
If you get these symptoms:
Tell your doctor or pharmacist.
4. Possible side effects
Reporting of side effects
Like all medicines, this medicine can cause side effects,
although not everybody gets them.
Tell your doctor straight away if you notice any of the
following serious side effects – you may need urgent
Heartbeat may go faster, slower or change rhythm
(affects up to 1 in 100 people).
Pain in the lower left side of the stomach and
bloody diarrhoea (ischaemic colitis – affects up to 1 in
Allergic reaction (affects up to 1 in 1,000 people).
The signs of allergy include rash; hives; itching;
wheezing; swollen eyelids, face or lips; complete
If you get any of these symptoms soon after taking Naramig:
Don’t take any more. Contact a doctor straight
Heaviness, pressure, tightness or pain in the
chest, throat or other parts of the body (affects up to 1
in 100 people). These effects may be intense but
generally pass quickly.
If these effects continue or become severe (especially
the chest pain):
Get medical help urgently. In a very small number of
people these symptoms can be caused by a heart
If you get any side effects, talk to your doctor, pharmacist or
nurse. This includes any possible side effects not listed in this
leaflet. You can also report side effects directly via the
Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.
By reporting side effects you can help provide more
information on the safety of this medicine.
5. How to store Naramig
Keep out of the sight and reach of children.
Do not store above 30°C.
Don’t take Naramig after the expiry date shown on the
carton. The expiry date refers to the last day of that
If your tablets appear to be discoloured or show any
other signs of deterioration, please return to your
pharmacist who will advise you.
If your doctor decides to stop your treatment, return
any left over tablets to the pharmacist. Only keep them
if your doctor tells you to.
Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help
to protect the environment.
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6. Contents of the pack and other
What Naramig contains
Each film-coated tablet contains 2.5mg naratriptan (as the
tablet core: microcrystalline cellulose, lactose,
croscarmellose sodium and magnesium stearate.
coating: hypromellose, titanium dioxide (E171), triacetin,
iron oxide (E172) and indigo carmine aluminium salt (E132).
What Naramig looks like and contents of the pack
Naramig are green, film-coated, D-shaped tablets, engraved
‘GX CE5’ on one side and plain on the reverse.
Your medicine is available in blister packs of 6 or 12 tablets.
This leaflet does not contain all the information about your
medicine. If you have any questions or are not sure about
anything, ask your doctor or pharmacist who have the
information you need, and will advise you.
Your medicine is manufactured by: Glaxo Operations UK Ltd.,
Glaxo Wellcome House, Berkeley Avenue, Greenford,
Middlesex, UB6 0NN.
GlaxoSmithKline Pharmaceuticals S.A., ul. Grunwaldzka 189,
60-322 Poznań, Poland.
Procured from within the EU and repackaged by:
Doncaster Pharmaceuticals Group Ltd., Kirk Sandall,
Doncaster, DN3 1QR.
Product Licence holder: Landmark Pharma Ltd.,
7 Regents Drive, Prudhoe, Northumberland, NE42 6PX.
PL No: 21828/0407
Leaflet issue and revision date (Ref): 19.12.16
Naramig® is a registered trademark of the GlaxoSmithKline
group of companies.
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Call 01302 365000 (Regulatory)
Product name: Naratriptan
Hydrochloride 2.5mg Tablets
Reference No: 21828/0407
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.