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MINITRAN 15

Active substance(s): GLYCERYL TRINITRATE / GLYCERYL TRINITRATE / GLYCERYL TRINITRATE

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8.25”

What is in this leaflet:
1. What Minitran patches are and what they
are used for
2. What you need to know before you use
Minitran patches
3. How to use Minitran patches
4. Possible side effects
5. How to store Minitran patches
6. Contents of the pack and other information
1. What Minitran patches are and what
they are used for

When you apply a Minitran patch to your
skin the medicine passes through your skin
and into your bloodstream.
Minitran patches are used to help prevent
angina attacks (chest pains). Minitran patches
may be used on their own, or with other treat­
ments for angina prescribed by your doctor.

Package leaflet: Information for the patient

Glyeryl trinitrate
5 mg, 10 mg or 15 mg
transdermal patches

Minitran



034872010367
XXXXXX

BC
FPO

The Minitran 5 mg patch is also used by
doctors and nurses to keep veins open and
improve blood flow when you are given a
drip (intravenous infusion).

BC
FPO

034872010367
XXXXXX

15.5”

Minitran patches contain the active substance
glyceryl trinitrate and belong to a group of
medicines called vasodilators which work
by widening blood vessels. This helps blood
which is carrying oxygen reach the muscle
in your heart.

Minitran



Glyeryl trinitrate
5 mg, 10 mg or 15 mg
transdermal patches

Package leaflet: Information for the patient

Read all of this leaflet carefully before
you start using this medicine because it
contains important information for you.
• Keep this leaflet. You may need to read it
again.
• If you have any further questions, ask your
doctor or pharmacist.
• This medicine has been prescribed for
you. Do not pass it on to others. It may
harm them, even if their signs of illness
are the same as yours.
• If you get any side effects, talk to your
doctor or pharmacist. This includes any
possible side effects not listed in this
­leaflet. See section 4.
• In this leaflet, Minitran 5 mg, 10 mg or
15 mg transdermal patches will be called
Minitran patches.

If you have angina it is important that you
receive effective treatment. If angina is left
untreated the muscle in your heart can
become starved of oxygen and this could
cause a potentially fatal heart attack
­(myocardial infarction).
2. What you need to know before you
use Minitran patches
Do not use Minitran patches if:
• You are taking Viagra (sildenafil) for
male erection problems. A severe and
potentially fatal drop in blood pressure
can occur if these two medicines are
used together
• You are allergic to glyceryl trinitrate or any
of the other ingredients in Minitran patches
(see Section 6)
• You have severe anaemia
• You have glaucoma (high pressure in your
eye) or you have been told that you have
high pressure inside the skull
• You have heart valve disease or percarditis
(inflammation of the lining of the heart)
• You have an angina attack. Your doctor will
give you a different medicine such as a GTN
spray for this
• Severe hypotension (systolic blood
­pressure less than 90 mmHg)
• Severe hypovolemia
• You are taking Riociguat a medicine used
to treat some types of hypertension.
If any of the above apply to you, talk to your
doctor or pharmacist.
Children and adolescents
Minitran patches are not recommended for
use in children.
Check with your doctor before using
Minitran patches if:
• You suffer from any heart or lung problems.
Minitran patches may have to be used under
your doctor’s supervision
• You are pregnant, or are trying to become
pregnant.
Other medicines and Minitran patches
Tell your doctor if you are taking any of the
following medicines:
• Medicines for failure to achieve an
erection such as Viagra. Using Minitran
with these medicines could cause a
severe drop in your blood pressure.

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This could make you unconscious and
may be fatal
• Other vasodilators such as nitrates, hydrala­
zine or minoxidil (used to treat high blood
pressure and angina)
• Medicines used to lower blood pressure
such as beta-blockers, ACE inhibitors and
diuretics (water tablets)
• Medicines to treat depression such as
amitriptyline and dothiepin
• Medicines to treat psychiatric illnesses
such as neuroleptics
• Medicines to treat pain, fever and inflam­
mation such as aspirin or any other
­non-steroidal anti-inflammatory drug
• Dihydroergotamine, a medicine used to
treat migraines
• Any other medicine, including medicines
obtained without a prescription.
• Riociguat a medicine used to treat some
types of hypertension.
These medicines can interfere with how well
your treatment works.

8.25” W x 15.5” H leaflet, Front
08 APR 2008
2.5”
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No Copy / Copy Area
(0.125” L and R, 0.25” T and B)
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Registration

Using Minitran patches with food and
drink
Do not drink alcohol whilst using Minitran
patches as this can cause your blood
­pressure to drop. This may make you feel
dizzy or faint.

BC
FPO

XXXXXX

Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think
you may be pregnant or are planning to
have a baby, ask your doctor or pharmacist
for advice before taking this medicine.

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Driving and using machines
Minitran patches may make you feel dizzy
and faint when you stand up. If this happens
to you, do not drive or use machinery.
3. How to use Minitran patches
Always use Minitran patches exactly as your
doctor or pharmacist has told you. Check
with your doctor or pharmacist if you are not
sure.
The usual starting dose is one Minitran 5 mg
patch per day.Your doctor or pharmacist will
have chosen the strength which best suits
your condition. You should check with your
doctor or pharmacist if you are unsure.

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Remember: Each Minitran patch is con­
tained in a sealed pouch. The sticky side of
the patch is covered by a disposable liner
which must be removed and thrown away
before the patch is applied to your skin.

Bar Code FPO
Bar Code (BC)/BC FPO is 1” W x 0.438” H
Artwork (AW) ID #/AW ID place holder area
is 1” W x 0.125” H
AW ID #/AW ID place holder is to be Arial or Helvetica
AW ID #/AW ID place holder is to be a minimum 6pt,
but must fit in AW ID area
BC, AW ID #, and AW ID place holders print black
AW ID place holder (X’s) is to be replaced with AW ID #
BC area is 1.5” W x 0.938” H (0.25” QZ L, R;
0.188 QZ T, B)
No copy other than BC, AW ID #, or place holders
in BC area
BC area is centered in the panel
BC area top, as the BC/BC FPO reads, is flush to
the first fold

15.

How many patches to use
Normally one patch per day is sufficient.
When to apply the patches
• At the start of your treatment, put on a
patch in the morning
• Remove the patch before you go to bed.

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You should have 8 to 12 hours without a
patch on. This will prevent you from becom­
ing tolerant to the medicine and will ensure
the treatment remains effective
• Each morning put on a new patch
• You can keep the patch in place whilst
bathing, showering or swimming.
How and where to apply the patch
• Choose a smooth area of skin to apply
the patch. The area should be hairless to
ensure good contact of the patch with the
skin. The chest, upper arm or shoulders
are suitable
• Your hands and the skin where you will
apply the patch should be clean and dry.

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Do not use powder or moisturiser.

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Instructions for applying a Minitran
patch
• S
 tarting at the notched corner of the pouch,
tear along the dotted line. Open the
pouch and remove the patch.

If you stop using Minitran patches

What Minitran patches look like

Do not stop using Minitran patches without
first talking to your doctor or pharmacist.

Minitran patches are oval shaped and come
in a square pouch or sachet with a tear-off
top. Each patch is protected by a clear,
­disposable, plastic film liner that must be
removed before use. The liner is split and
comes off as two pieces of film.
Minitran patches come in packs of 30.

4. Possible side effects
Like all medicines Minitran patches can
cause side effects, although not everybody
gets them.

• Fold the patch along the dotted line, so
that the backing comes apart.

• Hold the patch on one side and peel off
the backing on the other side to expose
the sticky patch. Discard the liner. Place
the sticky side of the patch directly onto
the skin.

Possible side effects include:

Marketing Authorisation Holder:

Very common (affects more than 1 in
10 people):
• Feeling and being sick.

Meda Pharmaceuticals Ltd
Skyway House
Parsonage Road
Takeley
Bishop’s Stortford, CM22 6PU.
United Kingdom.

Common (affects 1 in 100 people):
• Headache. This usually disappears after a
few days. If you have a lasting headache
you should talk to your doctor
Uncommon (affects 1 in 1,000 people):
• Slight reddening, itching or burning sen­
sation on the skin where you have applied
the patch. This usually disappears after
the patch has been removed
Rare (affects 1 in 10,000 people):
• An abnormally fast heart beat
• Hot flushes
Very rare (affects less than 1 in 10,000 people)
• Dizziness

• Peel off the remainder of the backing and
discard the liner. Press down firmly on the
patch with the palm of your hand.

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Not known (frequency cannot be estimated
from the available data)
• Skin rash
• Palpitations (noticeable pounding,
­fluttering or irregular heartbeat)
• Fainting
Reporting of side effects

Occasionally a patch may not stick or it may
fall off. If this happens apply a new patch to
a different area of the skin.
When applying the patch you must not:
• Stretch the skin
• Place the patch on a cut or reddened area
of skin
• Stick the same patch back on once it has
been removed from the skin.
When applying the patch you should
always:
• Place the new patch on a different area of
skin
• Allow several days to pass before applying
a fresh patch to the same area of skin.
For patients receiving an intravenous
infusion (drip)
Minitran patches can be used when you are
being given a drip. Your doctor or nurse will
decide on the strength of the patch required
and apply the patch next to the needle that
goes into the vein. The patch will be
changed daily. It will be removed once your
drip is stopped.
If you use more Minitran patches than
you should
Do not use more Minitran patches than you
should. If you accidentally apply too many
patches, remove the patches straight away
and immediately contact the nearest hospital
casualty department or your doctor.
An overdose of Minitran patches can cause
a rapid drop in blood pressure causing
­dizziness or fainting.
If you forget to use Minitran patches
If you forget to use a new patch apply it as
soon as you remember. If you are not sure
when to use your patch please ask your
doctor or pharmacist.

0.25”

8.25” W x 15.5” H leaflet, Back
08 APR 2008
2.5”
Die Line
Fold Line
No Copy / Copy Area
(0.125” L and R, 0.25” T and B)

Manufacturer:
3M Health Care Ltd
1 Morley Street
Loughborough
Leics LE11 1EP
United Kingdom.

2.5”

This leaflet was last revised in
February 2017

If this leaflet is difficult to
see or read, or you would
like it in a different format,
please contact
Meda Pharmaceuticals Ltd,
Skyway House, Parsonage
Road, Takeley, ­Bishop’s
Stortford, CM22 6PU.

Registration

2.5”

If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any
­possible side effects not listed in this leaflet.
You can also report side effects directly via
the Yellow Card Scheme at: www.mhra.gov.
uk/yellowcard.
By reporting side effects you can help pro­
vide more information on the safety of this
medicine.
5. How to store Minitran patches
Keep this medicine out of the sight and
reach of children.
Do not use Minitran patches after the expiry
date on the sachet. The expiry date refers to
the last day of that month. Store Minitran
patches at room temperature (below 25 °C)
in a dry place. Do not expose to light.
The shelf life for Minitran patches is three
years.
Do not throw away any medicines via waste­
water or household waste. Ask your phar­
macist how to throw away medicines you no
longer use. These measures will help pro­
tect the environment.

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6. Contents of the pack and other
­information

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What Minitran patches contain
The active substance in Minitran patches is
glyceryl trinitrate.
• The Minitran 5 mg patch contains 18 mg
of glyceryl trinitrate. The average amount
delivered into the bloodstream in 24 hours
is 5 mg
• The Minitran 10 mg patch contains 36 mg
of glyceryl trinitrate. The average amount
delivered into the bloodstream in 24 hours
is 10 mg
• The Minitran 15 mg patch contains 54 mg
of glyceryl trinitrate. The average amount
delivered into the bloodstream in 24 hours
is 15 mg.
The other ingredients are: isooctyl acrylate/
acrylamide copolymer, ethyl oleate, glyceryl
monolaurate.

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Minitran is a trademark of MEDA AB.
The Triangle Logo on the packaging is
a trademark of 3M and is used under license.
34-8720-1036-7
56UK1814110-03

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Expand Transcript

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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