Active substance(s): METRONIDAZOLE / METRONIDAZOLE / METRONIDAZOLE
0.8% W/V GEL
Read all of this leaflet carefully before you start using this medicine.
Keep this leaflet. You may need to read it again.
If you have any further questions, ask a doctor or pharmacist
This medicine has been prescribed for you. Do not pass it on to others. It may harm
them, even if their symptoms are the same as yours.
If any of the side effects becomes serious, or if you notice any side effects not listed
in this leaflet, please tell a doctor or pharmacist.
In this leaflet:
1. What Metrotop is and what it is used for
2. Before you use Metrotop
3. How to use Metrotop
4. Possible side effects
5. How to store Metrotop
6. Further information
1. WHAT METROTOP IS AND WHAT IT IS USED FOR
Metrotop is a clear water-based gel containing the active ingredient metronidazole.
Metronidazole is an anti-microbial agent that kills bacteria present in wounds (especially
bacteria found in wounds with poor oxygen supply).
Metrotop is used when tumours have produced open wounds on the skin surface and the
bacteria in these wounds are causing an unpleasant smell. The anti-microbial agent in
Metrotop kills the bacteria and so helps to reduce or remove the smell. Studies have
shown that applying Metrotop usually controls the odour in one to two weeks.
Metrotop can also be used to treat bad odours in leg ulcers and pressure sores.
2. BEFORE YOU USE METROTOP
Do not use Metrotop:
If you are allergic (hypersensitive) to metronidazole or any of the other ingredients of
Metrotop listed in section 6 of this leaflet.
Do not use Metrotop if the above applies to you. If you are not sure, talk to your doctor or
Taking other medicines
Please tell a doctor or healthcare professional if:
You are taking a blood-thinning medication such as coumarin or warfarin
You are taking Phenobarbital (a barbiturate used to treat seizures and fits)
You are taking, or have recently taken, any other medicines, including medicines
obtained without a prescription.
If you are not sure if the above applies to you, talk to your doctor or pharmacist before
Using Metrotop with food and drink
Avoid using alcohol while using Metrotop
Pregnancy and breast-feeding
Ask a doctor or pharmacist for advice before using Metrotop
Important information about some of the ingredients of Metrotop
Benzalkonium chloride is an irritant and may cause skin reactions.
HOW TO USE METROTOP
Always use Metrotop exactly as your doctor has told you. You should check with a doctor or
pharmacist if you are not sure.
Metrotop is for use on the skin only. Do not use Metrotop inside your body.
IF YOU ACCIDENTALLY SWALLOW ANY METROTOP, GO TO YOUR NEAREST
ACCIDENT AND EMERGENCY DEPARTMENT OR CONTACT YOUR DOCTOR
IMMEDIATELY. TAKE THIS LEAFLET AND ANY PACKAGING WITH YOU SO THEY
KNOW WHAT YOU HAVE TAKEN.
HOW TO USE METROTOP (continued)
For topical administration/application
The usual method of use is:
Clean the wounds thoroughly before application
Flat wounds: apply the gel generously over the entire wound area
Sunken wounds: loosely pack with paraffin gauze smeared with the gel
Cover the wound with a non-adherent dressing and a pad of lint or gauze
Apply the gel once or twice daily as necessary, or as directed by your doctor.
If you forget to use Metrotop
Apply the gel when you remember and continue as normal.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
POSSIBLE SIDE EFFECTS
No side effects have been reported when using Metrotop on the skin.
However, the following side effects have been reported when the active ingredient,
metronidazole, is taken by mouth:
shaky movements or
unpleasant taste in the mouth
darkening of the urine
You should talk to your doctor if any of these symptoms occur, or if notice any side effects
not listed in this leaflet.
Allergic reactions such as red raised
patches on the skin – these may
involve the lips, eyes or tongue
Nausea or vomiting
HOW TO STORE METROTOP
Keep out of the reach and sight of children.
Do not store above 25°C.
Do not use Metrotop after the expiry date which is stated on the carton and on the crimp
area of the tube. The expiry date relates to the last day of that month.
Once opened, the contents of the tube should be used within 28 days.
Metrotop should not be disposed of via wastewater of household waste. Ask a pharmacist
how to dispose of medicines no longer required. These measures will help to protect the
What Metrotop contains
The active substance is metronidazole
The other ingredients are hypromelose 4500, benzalkonium chloride solution and
What Metrotop looks like; and contents of the pack
Metrotop is a clear, water-based gel packed in a plastic tube and a cardboard outer carton.
Metrotop is available in 60g, 30g and 15g pack sizes.
MARKETING AUTHORISATION HOLDER AND MANUFACTURER
Marketing Authorisation Holder:
Ayrton Saunders Ltd
9 Arkwright Road
Astmoor Industrial Estate
Cheshire WA7 1NU
This leaflet was last approved in November 2012
Ayrton Saunders Ltd, 9 Arkwright Road, Astmoor Industrial Estate, Runcorn, Cheshire WA7
Metrotop is a trademark
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.