MAGNAPEN 125MG/125MG/5ML POWDER FOR ORAL SUSPENSION
Active substance(s): AMPICILLIN TRIHYDRATE / FLUCLOXACILLIN MAGNESIUM
Magnapen 125mg/125mg/5ml Powder for Oral Suspension
Co-fluampicil: 125mg Ampicilin/125mg Flucloxacillin
Read all of this leaflet carefully before you start using this medicine.
Keep this leaflet. You may need to read it again.
If you have further questions, please ask your doctor or nurse.
This medicine has been prescribed for you personally and you should not pass it on to others. It
may harm them, even if their symptoms are the same as yours. The name of your medicine is
Magnapen 125mg/125mg/5ml Powder for Oral Suspension. In the rest of this leaflet it is called
In this leaflet:
1. What Magnapen Suspension is and what it is used for
2. Before you take Magnapen Suspension
3. How to take Magnapen Suspension
4. Possible side effects
5. How to store Magnapen Suspension
6. Further information
What Magnapen Suspension is and what it is used for
Magnapen Suspension contains two active ingredients, ampicillin and flucloxacillin which together
are known as co-fluampicil. Magnapen Suspension is an antibiotic medicine. It belongs to the
penicillin group of antibiotics and works by killing bacteria that cause infections.
Magnapen Suspension is used to treat a wide range of infections caused by bacteria. These infections
may affect the chest, ear, nose, throat, skin and soft tissues.
In hospital this medicine may also be used to prevent and treat infections:
which occur after surgery
in patients receiving treatment which affects the immune system of the blood (septicaemia)
associated with difficulties in childbirth (septic abortion (abortion complicated by fever, often
leading to sepsis) and puerperal fever (an infection of the membrane of the uterus following childbirth
Before you take Magnapen Suspension
Do not take Magnapen Suspension if you:
know that you are allergic to penicillin, cephalosporins, any other antibiotic or any of the
ingredients contained in Magnapen Suspension (see ‘What Magnapen Suspension contain’
in section 6)
have ever had a skin rash or swelling of the face or neck when taking an antibiotic
have ever had a serious complaint, such as liver problems, when taking an antibiotic.
If any of the above statements apply to you, you should not be given Magnapen Suspension.
Speak to your doctor before taking Magnapen Suspension if you:
are being treated for kidney or liver problems
have glandular fever
are having blood tests because your medicine sometimes causes short-term changes to blood cell
Additional monitoring of kidney and liver function is recommended for patients on prolonged
treatment e.g. osteomyelitis (bone infection) or endocarditis (infection of the muscle around the heart).
If any of the above apply your doctor may decide to change the dose of Magnapen Suspension or
prescribe a different medicine.
Taking other medicines
Taking another medicine while you are taking Magnapen Suspension can affect how it or the other
medicine works. Please inform your doctor or pharmacist if you are taking or have recently taken any
other medicines, even those you may have brought yourself without a prescription.
Tell your doctor if you are using the following medicines (or any other medicines):
a contraceptive pill as you will need to take extra precautions such as use of a condom
probenecid and allopurinol, used in the treatment of gout
or if you are being treated with any other antibiotics.
If you are required to have a urine test, please inform your doctor you are taking Magnapen. False
positive results can occur with certain tests for sugar in the urine (e.g. the Fehling’s test) whilst taking
If you have any doubts about whether you should take this medicine then discuss matters with your
doctor before taking it.
Pregnancy and breast-feeding
You should let your doctor know if you are pregnant, think you might be pregnant or are breastfeeding before taking this medicine. Your doctor will decide if this medicine is suitable for you.
Important information for patients with an intolerance to some sugars
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor
before taking this medicinal product, as it contains sucrose.
How to take Magnapen Suspension
Always take Magnapen suspension exactly as your doctor has told you. You should check with
your doctor or pharmacist if you are not sure.
The dose of Magnapen suspension your doctor prescribes and the length of time for which you
will have to take it, will depend on your infection.
The usual dose of Magnapen suspension for the elderly, adults and children over 10 years of
age is two spoonfuls (10ml) four times a day.
The usual dose of Magnapen suspension for children under 10 years of age is one spoonful
(5ml) four times a day.
If your infection is severe, your doctor may double these doses.
Magnapen Suspension should be taken half an hour to one hour before food. If this medicine is
taken with food it may not work as well as it should.
Try to take this medicine as part of your daily routine and space the doses as evenly as possible
through the day – for example before meal times and at bedtime. You do not need to take a dose
in the middle of the night unless your doctor has told you to do so.
If you take more Magnapen Suspension than you should
If you take too much Magnapen Suspension contact your doctor or hospital casualty department
immediately. Take this leaflet and any remaining medicine with you. Symptoms of an overdose
include feeling sick, being sick and diarrhoea.
If you miss a dose of Magnapen Suspension
If you forget to take a dose at the right time, take it as soon as you remember. Then go on as before.
But don’t take the next dose too soon. Always try to keep the doses evenly spaced and do not take two
doses within one hour or so of each other.
If you stop taking Magnapen Suspension
Keep taking your suspension until the prescribed course is finished. Do not stop just because you feel
better. If you stop too soon, the infection may start up again. If you feel unwell at the end of your
course of treatment, tell your doctor.
Possible side effects
Like many medicines, Magnapen Suspension may cause side effects in some patients, particularly
when treatment is first started, although not everybody gets them.
Stop taking Magnapen Suspension and see your doctor immediately if you:
get severe diarrhoea with bleeding or stomach pain
notice your urine becoming darker or your faeces becoming paler
notice your skin or the whites of your eyes turning yellow
notice that your face is swollen and you have breathing problems
notice red or purple discolorations on the skin
start to itch or get a rash.
notice blistering of the skin, mouth, eyes or genitals
notice increased bleeding/bruising, pale skin or weakness (due to changes in the levels of certain
develop nephritis (inflammation of the kidneys that can cause swollen ankles or high blood
develop a fever.
Frequent side effects which are usually mild include:
nausea (feeling sick)
vomiting (being sick)
Some of these reactions can be delayed for several weeks after finishing the treatment.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme
By reporting side effects you can help provide more information on the safety of this medicine.
How to store Magnapen Suspension
Keep out of the reach and sight of children
Do not take the medicine after the expiry date printed on the pack. The expiry date refers to the last
day of that month.
Do not store above 25ºC. Keep the medicine in its original bottle and store in a refrigerator (2-8ºC).
If any medicine is left after two weeks (14 days), return it to your pharmacist.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to
dispose of medicines no longer required. These measures will help to protect the environment.
What Magnapen Suspension contains
Magnapen Suspension contains two active ingredients, ampicillin and flucloxacillin which together
are known as co-fluampicil. Each 5 ml of suspension contains 125mg ampicillin as ampicillin
trihydrate and 125mg of flucloxacillin as flucloxacillin magnesium.
Your medicine also contains inactive ingredients. These are sodium benzoate (E211), disodium
edentate, carmellose sodium, sodium citrate (E331), mono-ammonium glycyrrhizinate, blood orange
and menthol flavours, saccharin sodium and sucrose.
What Magnapen Suspension looks like and contents of the pack
Magnapen Suspension is an off white liquid mixture. It is available in a bottle containing 100ml of
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder: Wockhardt UK Ltd, Ash Road North, Wrexham, LL13 9UF, UK
Manufacturer: Laboratorio Reig Jofre, S.A, c/Jarama, 111. (Poligono Industrial) 45007 TOLEDO,
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This leaflet was last revised in 08/2015
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.