MAFAMOZ 62.5 mg/25
Package leaflet: Information for the user
Read all of this leaflet carefully before you start using this medicine because it
contains important information for you.
s Keep this leaflet. You may need to read it again.
s If you have any further questions, ask your doctor or pharmacist.
s This medicine has been prescribed for your child only. Do not pass it on to
others. It may harm them, even if their signs of illness are the same as your
s If your child gets any side effects, talk to your doctor or pharmacist. This
includes any possible side effects not listed in this leaflet. See section 4.
7HAT IS IN THIS LEAFLET
1. What Mafamoz 62.5 mg/25 mg Film-coated Tablets are and what they are
2. What you need to know before you use Mafamoz 62.5 mg/25 mg
3. How to use Mafamoz 62.5 mg/25 mg Film-coated Tablets
4. Possible side effects
5. How to store Mafamoz 62.5 mg/25 mg Film-coated Tablets
6. Contents of the pack and other information
1 What Mafamoz 62.5 mg/25 mg Film-coated Tablets are and what
they are used for
Mafamoz belongs to a group of medicines called antimalarials. It contains two
active ingredients, atovaquone and proguanil hydrochloride.
Mafamoz has two uses:
ss TO PREVENT MALARIA FOR CHILDREN WEIGHING BETWEEN KG AND KG
ss TO TREAT MALARIA FOR CHILDREN WEIGHING BETWEEN KG AND KG
Although this medicine is usually used for children and teenagers, it can be
PRESCRIBED FOR ADULTS WEIGHING LESS THAN KG
Malaria is spread by the bite of an infected mosquito, which passes the malaria
PARASITE Plasmodium falciparum into the bloodstream. Mafamoz prevents
malaria by killing this parasite. For people who are already infected with
malaria, Mafamoz also kills these parasites.
Protect your child from catching malaria
People of any age can get malaria. It is a serious disease, but is preventable. As
well as giving Mafamoz, it is very important that you also take steps to avoid
being bitten by mosquitoes.
ss 5SE INSECT REPELLENT ON EXPOSED AREAS OF THE SKIN
ss 7EAR LIGHT COLOURED CLOTHING THAT COVERS MOST OF THE BODY ESPECIALLY AFTER
sunset as this is the time when mosquitoes are most active
ss 3LEEP IN A SCREENED ROOM OR UNDER A MOSQUITO NET IMPREGNATED WITH
ss #LOSE WINDOWS AND DOORS AT SUNSET IF THEY ARE NOT SCREENED
ss #ONSIDER USING AN INSECTICIDE MATS SPRAY PLUG
INS TO CLEAR A ROOM OF INSECTS
or to deter mosquitoes from entering the room.
If you need further advice, talk to your doctor or pharmacist.
It is still possible to get malaria after taking the necessary precautions. Some
types of malaria infection take a long time to cause symptoms, so the illness
may not start until several days, weeks or even months after returning from
See a doctor immediately if your child gets symptoms such as high
temperature, headache, shivering and tiredness after returning home.
2 What you need to know before you use Mafamoz 62.5 mg/25 mg
Do not use Mafamoz:
ss IF YOUR CHILD IS ALLERGIC TO ATOVAQUONEPROGUANIL OR ANY OF THE OTHER INGREDIENTS
OF THIS MEDICINE LISTED IN SECTION
ss FOR PREVENTING MALARIA IF YOUR CHILD HAS SEVERE KIDNEY PROBLEMS
If any of the above applies to your child, talk to your doctor before your child
starts taking this medicine.
Warnings and precautions
Talk to your doctor before taking Mafamoz.
If your child is sick (vomits):
For preventing malaria:
ss IF YOUR CHILD IS SICK VOMITS WITHIN HOUR OF TAKING THE TABLET GIVE ANOTHER
dose straight away
ss IT IS IMPORTANT TO TAKE THE FULL COURSE OF -AFAMOZ )F YOUR CHILD HAS TO TAKE
EXTRA TABLETS DUE TO SICKNESS THEY MAY NEED ANOTHER PRESCRIPTION
ss IF YOUR CHILD HAS BEEN VOMITING IT IS ESPECIALLY IMPORTANT TO USE EXTRA
protection, such as repellents and bednets. Mafamoz may not be as effective,
as the amount absorbed will be reduced.
For treating malaria:
ss IF YOUR CHILD HAS VOMITING AND DIARRHOEA TELL YOUR DOCTOR THEY WILL NEED
regular blood tests. Mafamoz will not be as effective, as the amount absorbed
will be reduced. The tests will check whether the malaria parasite is being
cleared from their blood.
Other medicines and Mafamoz
4ELL YOUR DOCTOR OR PHARMACIST IF YOUR CHILD IS TAKINGUSING HAS RECENTLY
TAKENUSED OR MIGHT TAKEUSE ANY OTHER MEDICINE
Some medicines can affect the way Mafamoz works, or Mafamoz itself can
strengthen or weaken the effectiveness of other medicines taken at the same
time. These include:
ss METOCLOPRAMIDE USED TO TREAT NAUSEA AND VOMITING
ss THE ANTIBIOTICS TETRACYCLINE RIFAMPICIN AND RIFABUTIN
ss EFAVIRENZ OR CERTAIN HIGHLY ACTIVE PROTEASE
INHIBITORS USED TO TREAT ()6
ss WARFARIN AND OTHER MEDICINES THAT STOP BLOOD CLOTTING
ss ETOPOSIDE USED TO TREAT CANCER
Tell your doctor if your child is taking any of these. Your doctor may decide that
-AFAMOZ IS NOT SUITABLE FOR THEM OR THAT THEY NEED EXTRA CHECK UPS WHILST
Remember to tell your doctor if your child starts taking any other medicines
while they are taking Mafamoz.
Pregnancy, breast-feeding and fertility
)F YOUR CHILD IS PREGNANT OR BREAST
FEEDING THINK THEY MAY BE PREGNANT OR ARE
planning to have a baby, ask your doctor or pharmacist for advice before using
If your child is pregnant, do not give this medicine unless your doctor
Ask your doctor or pharmacist for advice before giving this medicine.
$O NOT BREAST
FEED WHILE TAKING -AFAMOZ AS THE INGREDIENTS MAY PASS INTO
breast milk and may harm the baby.
Driving and using machines
Mafamoz makes some people feel dizzy. If this happens to your child they
should not drive, use machines or take part in activities where they put
themselves or others at risk.
3 How to use Mafamoz 62.5 mg/25 mg Film-coated Tablets
!LWAYS USE THIS MEDICINE EXACTLY AS YOUR DOCTOR HAS TOLD YOU #HECK WITH YOUR
doctor or pharmacist if you are not sure.
The recommended dose is:
To prevent malaria
The usual dose to prevent malaria depends on your child’s weight.
KG n TABLET ONCE A DAY
KG n TABLETS ONCE A DAY AS A SINGLE DOSE
KG n TABLETS ONCE A DAY AS A SINGLE DOSE
3TART GIVING THIS MEDICINE n DAYS BEFORE TRAVELLING TO AN AREA WHICH HAS
#ONTINUE GIVING IT EVERY DAY DURING THE STAY
#ONTINUE GIVING IT FOR ANOTHER DAYS AFTER YOUR RETURN TO A MALARIA