KIRA LOWMOOD RELIEF
Active substance(s): ST JOHNS WORT EXTRACT
Low Mood relief
St. John’s Wort extract 450 mg
24 004 045 GB 04P0816 5694
Read all of this leaflet carefully before you start
taking this medicine because it contains important information for you.
– Keep this leaflet. You may need to read it again.
– If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side
effects not listed in this leaflet. See section 4.
– You must talk to a doctor if you do not feel better or
if you feel worse after 6 weeks.
What is in this leaflet
1. What Kira® LowMood relief is and what it is used for
2. What you need to know before you take Kira®
3. How to take Kira® LowMood relief
4. Possible side effects
5. How to store Kira® LowMood relief
6. Contents of the pack and other information
1. What Kira LowMood relief is and what it is
This product is a traditional herbal medicinal product
containing St. John’s Wort extract. Each film-coated
tablet contains 450 mg extract (as dry extract) from
St. John’s Wort aerial parts (Hypericum perforatum L.)
(3-6:1) (equivalent to 1350–2700 mg of St. John’s
Wort). Extraction solvent: Methanol 80 % v/v.
– Stop using it at least 10 days prior to undergoing
Kira® LowMood relief is a traditional herbal medicinal
product used to relieve the symptoms of slightly low
mood and mild anxiety. This usage is based on tradi
tional use only.
You must talk to a doctor if you do not feel better or if
you feel worse after 6 weeks.
Driving and using machines
St. John’s Wort may make you feel dizzy or sleepy. If
affected do not drive or use machines.
2. What you need to know before you take Kira
Do not take Kira® LowMood relief if:
– You are allergic to peanut and soya
– You are allergic to St. John’s Wort or any of the
other ingredients (listed in section 6)
– You are under 18 years of age
– You are pregnant or breast-feeding
– Your skin is exceptionally sensitive to sunlight
– You are having light treatment (phototherapy) for
– You are suffering from depression (see below)
Warnings and precautions
Are you suffering from depression?
Symptoms of depression include feelings of helplessness and hopelessness, loss of interest in daily activities, appetite or weight changes, sleep changes, loss
of energy and difficulty concentrating. If your doctor
has told you that you are suffering from depression
do not take this product. If you think you are suffering from depression you should tell your doctor.
This product contains lactose and soy polysaccharides. Tell your doctor before taking this product if you
have an intolerance to some sugars (see section 6).
Patients who are allergic to peanut or soya must not
use this medicinal product.
While you are taking this product:
– Avoid excessive sunbathing or the use of sunbeds/
Other medicines and Kira LowMood relief
Tell your doctor or pharmacist if you are taking, have
recently taken or might take any other medicines.
St. John’s Wort can affect the way some medicines
work and reduce their effectiveness. Medicines that
can be affected by St. John’s Wort include prescrip
tion medicines, and those that you may have bought
yourself without a prescription.
Therefore it is important that you do not take St.
John’s Wort if you are using any of the medicines
DO NOT TAKE THIS PRODUCT IF YOU ARE TAKING ANY OF THE FOLLOWING MEDICINES
All hormonal contraceptives
The birth control “Pill”, emergency contraception (known as ‘the
morning after pill‘), hormonal implants, creams, patches, intra-uterine
devices with hormones
All medicines for depression/anxiety
Amitriptyline, clomipramine, moclobemide, citalopram, escitalopram,
fluoxetine, fluvoxamine, paroxetine, sertraline, duloxetine, venlafaxine
All hormonal replacement therapy (HRT)
HRT tablets, patches, gels, vaginal rings
All medicines for thinning the blood
All medicines for epilepsy
Carbamazepine, phenobarbitone, phenytoin, primidone, sodium
All immunosuppressant medicines
All medicines for HIV infections
Amprenavir, atazanavir, darunavir, fosamprenavir, indinavir, lopinavir,
nelfinavir, ritonavir, saquinavir, tipranavir, efivarenz, nevirapine,
Some medicines for cholesterol
Some medicines for cancer
Irinotecan, dasatinib, erlotinib, imatinib, sorafenib, sunitinib,
Some medicines for heart disease
Digoxin, ivabradine, amiodarone
Some medicines for migraines
Almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan,
Some medicines for high blood pressure
Amlodipine, nifedipine, felodipine, verapamil
A medicine for regulating mood
A thyroid hormone
St. John’s Wort may also affect the following medi
cines. Therefore do not take this product with these
medicines unless a doctor has said it is safe to do so:
• Fentanyl, propofol, sevoflurane and midazolam
• Tramadol (an analgesic)
• Erythromycin, clarithromycin and telithromycin
• Itraconazole and voriconazole (antifungals)
• Artemether and lumefantrine (antimalarials)
• Rasagiline (anti-Parkinson’s medicine)
• Aripiprazole (antipsychotic medicine)
• Buspirone (anxiolytic)
• Aprepitant (to treat vomiting)
• Butobarbital and Phenobarbital (barbiturates)
• Methyl phenidate (central nervous system or CNS
• Exemestane (hormone antagonist)
• Eplerenone (diuretic)
• Lansoprazole and omeprazole (proton pump
• Theophylline (bronchodilator)
If you forget to take Kira ® LowMood relief
Do not take a double dose to make up for a forgotten
If you have any questions, or are unsure about
anything, please ask your doctor, pharmacist or qualified healthcare practitioner.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following side effects have been reported:
– gastrointestinal disorders such as indigestion, loss
of appetite, nausea, diarrhoea, constipation
– allergic skin reactions such as rash, hives or itching of the skin. If you experience allergic skin
reactions, stop taking the product and consult
Also sunburn-like reactions on skin exposed to strong
sunlight or strong ultraviolet (UV) irradiation e.g. solarium have been reported, particularly in fair skinned
Other side effects that have been reported include
headaches, nerve pain or tingling, anxiety, dizziness
The frequency of these effects occuring is not known.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed
in this leaflet. You can also report side effects directly
via the Yellow Card Scheme,
By reporting side effects you can help provide more
information on the safety of this medicine.
5. How to store Kira ® LowMood relief
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is
stated on the carton and blister. The expiry date refers
to the last day of that month.
Do not throw away any medicines via wastewater or
household waste. Ask your pharmacist how to throw
away medicines you no longer longer use. These
measures will help to protect the environment.
Store the tablets in a cool dry place.
Do not store above 25° C.
Store in original package.
Keep your tablets in the blister pack until it is time to
6. Contents of the pack and other information
What Kira® LowMood relief contains
– The active substance is 450 mg of extract (as dry
extract) from St. John’s Wort aerial parts
(Hypericum perforatum L.) (3–6:1) (equivalent to
1350–2700 mg of St. John’s Wort). Extraction solvent: Methanol 80 % v/v.
– The other ingredients are:
Extract excipients: Lactose monohydrate, silica colloidal anhydrous
Tablet core: Cellulose microcrystalline, silica colloidal
anhydrous, soy polysaccharides, long-chain partial
Film-coating: Hypromellose, cellulose microcrystalline, stearic acid, titanium dioxide (E171), iron oxide
hydrate E 172 (yellow iron oxide), vanillin.
Each film-coated tablet contains 19.15 mg of lactose
and 42 mg of soy polysaccharides.
What Kira® LowMood looks like and contents of
Each pack contains 30 or 60 film-coated tablets. The
film-coated tablets are yellow with smooth, undam
Cassella-med GmbH is a company of the