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IPRATROPIUM BROMIDE 20 MICROGRAMS CFC-FREE INHALER

Active substance(s): IPRATROPIUM BROMIDE

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Package leaflet: Information for the user

Atrovent® 20 micrograms
CFC-Free Inhaler
(ipratropium bromide)






Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or
pharmacist.
This medicine has been prescribed for you. Do not pass it on to
others. It may harm them, even if their symptoms are the same
as yours.
If any of the side effects gets troublesome or serious, or if you
notice any side effects not listed in this leaflet, please tell your
doctor or pharmacist.

The name of your medicine is Atrovent 20 micrograms CFC-Free
Inhaler but it will be referred to as Atrovent throughout this leaflet.
In this leaflet:
1. What Atrovent is and what it is used for
2. Before you use Atrovent
3. How to use Atrovent
4. Possible side effects
5. How to store Atrovent
6. Further information
1. WHAT ATROVENT IS AND WHAT IT IS USED FOR
Atrovent is an inhaler and contains a medicine called ipratropium
bromide. This belongs to a group of medicines called
bronchodilators. It is used to make breathing easier for people with
asthma or ‘chronic obstructive pulmonary disease’ (COPD), often
referred to as chronic bronchitis. You may have difficulty breathing,
shortness of breath, wheezing or tightness in your chest.
Atrovent works by opening up your airways.
2. BEFORE YOU USE ATROVENT
Do not use Atrovent if:
• You are allergic (hypersensitive) to ipratropium or any of the
other ingredients in ATROVENT. (Listed in section 6: Further
information)
• You are allergic to similar medicines which contain atropine or
medicines like atropine
• You are pregnant, think you are pregnant, likely to get pregnant
or are breast-feeding
Do not use if any of the above apply to you. If you are not sure, talk
to your doctor or pharmacist before using Atrovent.
Take special care with Atrovent
Check with your doctor or pharmacist before using this medicine if:
• You have glaucoma, or have been told that you may develop it
• You have problems passing water (urine)
• You are a man who has prostate problems
• You have cystic fibrosis
If you are not sure if any of these apply to you, talk to your doctor or
pharmacist before using Atrovent.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have
recently taken any other medicines, including any inhalers and
medicines obtained without a prescription. This includes herbal
medicines. This is because Atrovent can affect the way some other
medicines work. Also some other medicines can affect the way
Atrovent works.
In particular, tell your doctor or pharmacist if you are taking/ have
taken any of the following medicines:
• Other inhalers to help you to breathe more easily such as the
reliever inhaler salbutamol
• Medicines called ‘xanthines’ to help your breathing such as
theophylline and aminophylline
If you are not sure if any of the above apply to you, talk to your
doctor or pharmacist before using Atrovent.
Pregnancy and breast-feeding
Do not use Atrovent if you are pregnant, think you are pregnant,
likely to get pregnant or are breast-feeding.
Driving and using machines
You may feel dizzy, or have difficulty in focusing, or blurred vision
while taking Atrovent. If this happens do not drive or use any tools
or machines.

Operations
If you attend a hospital appointment or are admitted to hospital, be
sure to take your inhaler(s) and any other medicines (in their
packaging if possible) with you. Some gases used in operations
(anaesthetic gases) may affect how your inhaler works. If you are
about to have surgery, make sure you mention that you are taking
Atrovent to the doctor, dentist or anaesthetist.
3. HOW TO USE ATROVENT
Always use Atrovent exactly as your doctor has told you. You
should check with your doctor or pharmacist if you are not sure.
Follow these instructions to get the best results. If anything is
unclear after reading this leaflet, ask your doctor or pharmacist.
You may notice that this CFC-Free inhaler tastes slightly different
from the last CFC-containing inhaler you used. This is normal.
The inhaler is still as safe and will work as well as your last one.
How much to use
Adults (including the elderly)
• One or two puffs to be inhaled three or four times daily
• Sometimes, in early treatment, up to four puffs at a time may be
taken
Children 6-12 yrs


One or two puffs to be inhaled three times daily

Children under 6 yrs


One puff to be inhaled three times daily

When children are using this medicine they must be supervised by
a responsible adult.
Do not use more than your doctor has told you
See your doctor straight away if:
• You feel that your inhaler is not working as well as usual
• You need to use the inhaler more than your doctor has
recommended
Your doctor may need to check how well your medicine is working.
In some cases your doctor may need to change your medicine.
Testing Your Inhaler
To make sure that your inhaler is working, test fire it twice into the
air before using it for the first time and whenever your inhaler has
not been used for 3 days or more.
How to use your inhaler
Read through numbers 1 to 6 first, before starting to use your
inhaler.
Remove the cap from the mouthpiece.

Hold the inhaler as shown in the picture
(with the arrow on the label pointing
upwards) and breathe out gently.

• Then straight away, put the mouthpiece
in your mouth.
• Hold the mouthpiece with your lips.
• Start to breathe in slowly and deeply
through your mouth.
• Press the top of the inhaler firmly. This
will release one puff of your medicine.
• Keep breathing in.
• Hold your breath for as long as is
comfortable.
• If possible hold your breath for 10
seconds.
• Then breathe out slowly.

• If you are having more than one puff,
wait at least 1 minute before the next
puff.
• Then repeat steps 2, 3 and 4.
After use, replace the cap on the
mouthpiece.

The mouthpiece has been designed specially for use with this
product only. Do not use any other mouthpiece with the product and
do not use the mouthpiece provided here with any other product.
If you find breathing in and pressing the inhaler at the same time
(step 3) difficult you should talk to your doctor or pharmacist, as you
could use a spacer device (Aerochamber Plus™) with your inhaler.
A spacer is a device designed to make step 3 easier. A spacer is
generally a plastic container with a mouthpiece at one end and a
hole for inserting the mouthpiece of the inhaler at the other end.
The puff of medicine from your inhaler is sprayed into the spacer
and the puff of medicine stays there, inside the spacer, until you
breathe in through your mouth from the spacer with the spacer
mouthpiece in your mouth and with your lips closed around it. This
means that you do not have to worry about breathing in and
pressing the inhaler at the same time.
When using your Atrovent take care not to let any of the spray enter
your eyes. If any of the spray accidentally gets into your eyes you
may get painful, stinging or red eyes, dilated pupils, blurred vision,
see colours or lights. If this happens, talk to your doctor for advice.
If you get problems with your eyes at any other time, talk to your
doctor for advice. You may be developing glaucoma, which will
need treatment straight away.
Cleaning
It is important to clean your inhaler regularly. Otherwise it may not
work properly.





Remove the canister and cap
Wash and clean the white mouthpiece in warm soapy water
Rinse in warm water and allow to air-dry without using any
heating system
Make sure the small hole in the mouthpiece is washed through
thoroughly
Once the white mouthpiece is dry, replace the canister and the
cap

Uncommon (affects less than 1 in 100 people)
• Itching, skin rash
• Unexpected tightness of the chest, swelling of the throat, dry
throat
• Blurred vision, dilated pupils, glaucoma, painful, stinging, red or
swelling of the eyes, see colours or lights
• Diarrhoea, constipation or being sick
• Mouth or lip sores
• Problems passing water (urine), especially if you already have
problems passing urine
Rare (affects less than 1 in 1000 people)
• Difficulty focusing
• Nettle rash (urticaria)
If any of the side effects gets troublesome or serious, or if you
notice any side effects not listed in this leaflet, tell your doctor or
pharmacist.
If any of the spray accidentally gets into your eyes you may get
painful, stinging or red eyes, dilated pupils, blurred vision, see
colours or lights. If this happens, talk to your doctor for advice. If
you get problems with your eyes at any other time, talk to your
doctor for advice. You may be developing glaucoma, which will
need treatment straight away. If your eyes are affected in any way
do not drive or operate machinery.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You
can also report side effects directly via the Yellow Card Scheme at:
www.mhra.gov.uk/yellowcard 
By reporting side effects, you can help provide more information on
the safety of this medicine.

Make sure you do not run out of Atrovent
The inhaler has been designed to deliver 200 puffs of your
medicine. However, it is not possible to tell when the inhaler is
empty and when the 200 puffs have been used. There may still be a
small amount of fluid left over in the container. Please make sure
that your inhaler is replaced after you have taken 200 puffs (usually
after 3-4 weeks of regular use) so that you can be certain that you
are getting the right amount of your medicine in each puff.

5. HOW TO STORE ATROVENT
• Keep out of the sight and reach of children
• Do not take your medicine after the expiry date which is stated
on the carton and the canister label after ‘Exp’. The expiry date
refers to the last day of that month.
• Do not store above 25°C.
• Do not freeze.
• Keep pressurised container away from heat and light.
• Do not expose to temperatures higher than 50°C.
• The canister contains a pressurised liquid. Do not pierce or
burn container even when empty.

If you use more Atrovent than you should
If you use more of this inhaler than you should, talk to a doctor or
go to a hospital straight away. Take all your inhalers and any other
medicines you are taking (in their packaging if possible) with you. If
you take too much or too many puffs you may get a dry mouth, a
rapid heart rate or blurred vision.

6. FURTHER INFORMATION
What Atrovent contains
The active ingredient is ipratropium bromide.
Each actuation contains 20 micrograms ipratropium bromide (as the
monohydrate.)



If you forget to take Atrovent
• If you forget a dose, inhale it as soon as you remember it.
• However, if it is time for the next dose, skip the missed dose.
• Do not take a double dose to make up for a forgotten dose.
If you have any further questions, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Atrovent can cause side effects, although not
everybody gets them.
Tell your doctor straight away if you notice any the following
serious side effects - you may need urgent medical treatment:
• If after taking Atrovent you are wheezy or have other difficulties
in breathing, do not take any more (unless you have been told
to by your doctor). You may need to take a fast-acting reliever
inhaler such as salbutamol to help your breathing. Your doctor
may decide that you need different medicines to help your
breathing
• Allergic reactions - the signs may include skin rash and itching
(affects less than 1 in 100 people). In severe cases the signs
include swelling of your mouth and face, sudden difficulties in
breathing and reduction of your blood pressure. Tightening of
your throat (affects less than 1 in 100 people)
• Palpitations (fast or uneven heart beats) or quickening of the
heart rate (affects less than 1 in 100 people)
• Increased heart rate or irregular heart rhythm such as atrial
fibrillation (affects less than 1 in 1000 people)
See your doctor straight away if you have any of these side effects.
The side effects described below have been experienced by people
taking Atrovent and they are listed as either common, uncommon or
rare.
Common (affects less than 1 in 10 people)

Headache, dizziness
• Dry mouth, feeling sick (nausea), stomach upset or discomfort
• Cough and throat irritation when you have just used Atrovent

Other ingredients are HFA-134a (1,1,1,2-tetrafluoroethane),
citric acid anhydrous, ethanol anhydrous and purified water.
Atrovent does not contain any chlorofluorocarbon (CFC)
propellants.
You may have been prescribed Atrovent inhaler CFC-Free as you
were previously being treated with Atrovent inhaler. These products
contain the same medicine, ipratropium bromide, but different
propellants. Propellants are ingredients which enable the delivery of
the medicine to the lungs. Atrovent inhaler contained
chlorofluorocarbons or CFCs as propellants which are known to
damage the ozone layer. Your Atrovent has been developed to
include the new propellant HFA-134a which does not damage the
ozone layer i.e. Atrovent does not contain any CFCs. In terms of
safety and effectiveness the CFC-Free product is the same as the
old CFC-containing product.
What Atrovent looks like and contents of the pack
Atrovent is an inhaler, in which a stainless steel pressurised
canister with metering valve and outer clear and white body with a
green cap. The canister is filled with a clear, colourless liquid.
Each canister contains 10ml solution (200 actuations).
Each carton contains one inhaler.
Manufactured by: Boehringer Ingelheim Pharma GmbH & Co. KG,
Binger Strasse 173, D-55216 Ingelheim/Rhein, Germany.
Procured from within the EU and repackaged by the Product
Licence holder: B&S Healthcare, Unit 4, Bradfield Road, Ruislip,
Middlesex, HA40NU, UK.
®

Atrovent 20 micrograms CFC-Free Inhaler

POM

PL No: 18799/2394
Leaflet date: 29.01.2015
Atrovent is a registered trademark of Boehringer Ingelheim.

Package leaflet: Information for the user

Ipratropium bromide
20 micrograms CFC-Free
Inhaler



Keep this leaflet. You may need to read it again.
If you have any further questions, ask your doctor or
pharmacist.
• This medicine has been prescribed for you. Do not pass it on to
others. It may harm them, even if their symptoms are the same
as yours.
• If any of the side effects gets troublesome or serious, or if you
notice any side effects not listed in this leaflet, please tell your
doctor or pharmacist.
The name of your medicine is Ipratropium bromide 20 micrograms
CFC-Free Inhaler but it will be referred to as Ipratropium throughout
this leaflet.
In this leaflet:
1. What Ipratropium is and what it is used for
2. Before you use Ipratropium
3. How to use Ipratropium
4. Possible side effects
5. How to store Ipratropium
6. Further information
1. WHAT IPRATROPIUM IS AND WHAT IT IS USED FOR
Ipratropium is an inhaler and contains a medicine called ipratropium
bromide. This belongs to a group of medicines called
bronchodilators. It is used to make breathing easier for people with
asthma or ‘chronic obstructive pulmonary disease’ (COPD), often
referred to as chronic bronchitis. You may have difficulty breathing,
shortness of breath, wheezing or tightness in your chest.
Ipratropium works by opening up your airways.
2. BEFORE YOU USE IPRATROPIUM
Do not use Ipratropium if:
• You are allergic (hypersensitive) to ipratropium or any of the
other ingredients in Ipratropium. (Listed in section 6: Further
information)
• You are allergic to similar medicines which contain atropine or
medicines like atropine
• You are pregnant, think you are pregnant, likely to get pregnant
or are breast-feeding
Do not use if any of the above apply to you. If you are not sure, talk
to your doctor or pharmacist before using Ipratropium.
Take special care with Ipratropium
Check with your doctor or pharmacist before using this medicine if:
• You have glaucoma, or have been told that you may develop it
• You have problems passing water (urine)
• You are a man who has prostate problems
• You have cystic fibrosis
If you are not sure if any of these apply to you, talk to your doctor or
pharmacist before using Ipratropium.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have
recently taken any other medicines, including any inhalers and
medicines obtained without a prescription. This includes herbal
medicines. This is because Ipratropium can affect the way some
other medicines work. Also some other medicines can affect the
way Ipratropium works.
In particular, tell your doctor or pharmacist if you are taking/ have
taken any of the following medicines:
• Other inhalers to help you to breathe more easily such as the
reliever inhaler salbutamol
• Medicines called ‘xanthines’ to help your breathing such as
theophylline and aminophylline
If you are not sure if any of the above apply to you, talk to your
doctor or pharmacist before using Ipratropium.
Pregnancy and breast-feeding
Do not use Ipratropium if you are pregnant, think you are pregnant,
likely to get pregnant or are breast-feeding.
Driving and using machines
You may feel dizzy, or have difficulty in focusing, or blurred vision
while taking Ipratropium. If this happens do not drive or use any
tools or machines.

Operations
If you attend a hospital appointment or are admitted to hospital, be
sure to take your inhaler(s) and any other medicines (in their
packaging if possible) with you. Some gases used in operations
(anaesthetic gases) may affect how your inhaler works. If you are
about to have surgery, make sure you mention that you are taking
Ipratropium to the doctor, dentist or anaesthetist.
3. HOW TO USE IPRATROPIUM
Always use Ipratropium exactly as your doctor has told you. You
should check with your doctor or pharmacist if you are not sure.
Follow these instructions to get the best results. If anything is
unclear after reading this leaflet, ask your doctor or pharmacist.
You may notice that this CFC-Free inhaler tastes slightly different
from the last CFC-containing inhaler you used. This is normal.
The inhaler is still as safe and will work as well as your last one.
How much to use
Adults (including the elderly)
• One or two puffs to be inhaled three or four times daily
• Sometimes, in early treatment, up to four puffs at a time may be
taken
Children 6-12 yrs


One or two puffs to be inhaled three times daily

Children under 6 yrs


One puff to be inhaled three times daily

When children are using this medicine they must be supervised by
a responsible adult.
Do not use more than your doctor has told you
See your doctor straight away if:
• You feel that your inhaler is not working as well as usual
• You need to use the inhaler more than your doctor has
recommended
Your doctor may need to check how well your medicine is working.
In some cases your doctor may need to change your medicine.
Testing Your Inhaler
To make sure that your inhaler is working, test fire it twice into the
air before using it for the first time and whenever your inhaler has
not been used for 3 days or more.
How to use your inhaler
Read through numbers 1 to 6 first, before starting to use your
inhaler.
Remove the cap from the mouthpiece.

Hold the inhaler as shown in the picture
(with the arrow on the label pointing
upwards) and breathe out gently.

• Then straight away, put the mouthpiece
in your mouth.
• Hold the mouthpiece with your lips.
• Start to breathe in slowly and deeply
through your mouth.
• Press the top of the inhaler firmly. This
will release one puff of your medicine.
• Keep breathing in.
• Hold your breath for as long as is
comfortable.
• If possible hold your breath for 10
seconds.
• Then breathe out slowly.

• If you are having more than one puff,
wait at least 1 minute before the next
puff.
• Then repeat steps 2, 3 and 4.
After use, replace the cap on the
mouthpiece.

The mouthpiece has been designed specially for use with this
product only. Do not use any other mouthpiece with the product and
do not use the mouthpiece provided here with any other product.
If you find breathing in and pressing the inhaler at the same time
(step 3) difficult you should talk to your doctor or pharmacist, as you
could use a spacer device (Aerochamber Plus™) with your inhaler.
A spacer is a device designed to make step 3 easier. A spacer is
generally a plastic container with a mouthpiece at one end and a
hole for inserting the mouthpiece of the inhaler at the other end.
The puff of medicine from your inhaler is sprayed into the spacer
and the puff of medicine stays there, inside the spacer, until you
breathe in through your mouth from the spacer with the spacer
mouthpiece in your mouth and with your lips closed around it. This
means that you do not have to worry about breathing in and
pressing the inhaler at the same time.
When using your Ipratropium take care not to let any of the spray
enter your eyes. If any of the spray accidentally gets into your eyes
you may get painful, stinging or red eyes, dilated pupils, blurred
vision, see colours or lights. If this happens, talk to your doctor for
advice. If you get problems with your eyes at any other time, talk to
your doctor for advice. You may be developing glaucoma, which will
need treatment straight away.
Cleaning
It is important to clean your inhaler regularly. Otherwise it may not
work properly.





Remove the canister and cap
Wash and clean the white mouthpiece in warm soapy water
Rinse in warm water and allow to air-dry without using any
heating system
Make sure the small hole in the mouthpiece is washed through
thoroughly
Once the white mouthpiece is dry, replace the canister and the
cap

Uncommon (affects less than 1 in 100 people)
• Itching, skin rash
• Unexpected tightness of the chest, swelling of the throat, dry
throat
• Blurred vision, dilated pupils, glaucoma, painful, stinging, red or
swelling of the eyes, see colours or lights
• Diarrhoea, constipation or being sick
• Mouth or lip sores
• Problems passing water (urine), especially if you already have
problems passing urine
Rare (affects less than 1 in 1000 people)
• Difficulty focusing
• Nettle rash (urticaria)
If any of the side effects gets troublesome or serious, or if you
notice any side effects not listed in this leaflet, tell your doctor or
pharmacist.
If any of the spray accidentally gets into your eyes you may get
painful, stinging or red eyes, dilated pupils, blurred vision, see
colours or lights. If this happens, talk to your doctor for advice. If
you get problems with your eyes at any other time, talk to your
doctor for advice. You may be developing glaucoma, which will
need treatment straight away. If your eyes are affected in any way
do not drive or operate machinery.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You
can also report side effects directly via the Yellow Card Scheme at:
www.mhra.gov.uk/yellowcard
By reporting side effects, you can help provide more information on
the safety of this medicine.

Make sure you do not run out of Ipratropium
The inhaler has been designed to deliver 200 puffs of your
medicine. However, it is not possible to tell when the inhaler is
empty and when the 200 puffs have been used. There may still be a
small amount of fluid left over in the container. Please make sure
that your inhaler is replaced after you have taken 200 puffs (usually
after 3-4 weeks of regular use) so that you can be certain that you
are getting the right amount of your medicine in each puff.

5. HOW TO STORE IPRATROPIUM
• Keep out of the sight and reach of children
• Do not take your medicine after the expiry date which is stated
on the carton and the canister label after ‘Exp’. The expiry date
refers to the last day of that month.
• Do not store above 25°C.
• Do not freeze.
• Keep pressurised container away from heat and light.
• Do not expose to temperatures higher than 50°C.
• The canister contains a pressurised liquid. Do not pierce or
burn container even when empty.

If you use more Ipratropium than you should
If you use more of this inhaler than you should, talk to a doctor or
go to a hospital straight away. Take all your inhalers and any other
medicines you are taking (in their packaging if possible) with you. If
you take too much or too many puffs you may get a dry mouth, a
rapid heart rate or blurred vision.

6. FURTHER INFORMATION
What Ipratropium contains
The active ingredient is ipratropium bromide.
Each actuation contains 20 micrograms ipratropium bromide(as the
monohydrate)



If you forget to take Ipratropium
• If you forget a dose, inhale it as soon as you remember it.
• However, if it is time for the next dose, skip the missed dose.
• Do not take a double dose to make up for a forgotten dose.
If you have any further questions, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Ipratropium can cause side effects, although not
everybody gets them.
Tell your doctor straight away if you notice any the following
serious side effects - you may need urgent medical treatment:
• If after taking Ipratropium you are wheezy or have other
difficulties in breathing, do not take any more (unless you have
been told to by your doctor). You may need to take a fast-acting
reliever inhaler such as salbutamol to help your breathing. Your
doctor may decide that you need different medicines to help
your breathing
• Allergic reactions - the signs may include skin rash and itching
(affects less than 1 in 100 people). In severe cases the signs
include swelling of your mouth and face, sudden difficulties in
breathing and reduction of your blood pressure. Tightening of
your throat (affects less than 1 in 100 people)
• Palpitations (fast or uneven heart beats) or quickening of the
heart rate (affects less than 1 in 100 people)
• Increased heart rate or irregular heart rhythm such as atrial
fibrillation (affects less than 1 in 1000 people)
See your doctor straight away if you have any of these side effects.
The side effects described below have been experienced by people
taking Ipratropium and they are listed as either common,
uncommon or rare.
Common (affects less than 1 in 10 people)
• Headache, dizziness
• Dry mouth, feeling sick (nausea), stomach upset or discomfort
• Cough and throat irritation when you have just used Ipratropium

Other ingredients are HFA 134a (1,1,1,2-tetrafluoroethane), citric
acid anhydrous, ethanol anhydrous and purified water.
Ipratropium does not contain any chlorofluorocarbon (CFC)
propellants.
You may have been prescribed Ipratropium inhaler CFC-Free as
you were previously being treated with Ipratropium inhaler. These
products contain the same medicine, ipratropium bromide, but
different propellants. Propellants are ingredients which enable the
delivery of the medicine to the lungs. Ipratropium inhaler contained
chlorofluorocarbons or CFCs as propellants which are known to
damage the ozone layer. Your Ipratropium has been developed to
include the new propellant HFA-134a which does not damage the
ozone layer i.e. Ipratropium does not contain any CFCs. In terms of
safety and effectiveness the CFC-Free product is the same as the
old CFC-containing product.
What Ipratropium looks like and contents of the pack
Iratropium is an inhaler in which a stainless steel pressurised
canister with metering valve and outer clear and white body with a
green cap. The canister is filled with a clear, colourless liquid.
Each canister contains 10ml solution (200 actuations).
Each carton contains one inhaler.
Manufactured by: Boehringer Ingelheim Pharma GmbH & Co. KG,
Binger Strasse 173, D-55216 Ingelheim/Rhein, Germany.
Procured from within the EU and repackaged by the Product
Licence holder: B&S Healthcare, Unit 4, Bradfield Road, Ruislip,
Middlesex, HA40NU, UK.
Ipratropium bromide 20 micrograms CFC-Free Inhaler
PL No: 18799/2394
Leaflet date: 29.01.2015

POM

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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