Skip to Content

INTRAFUSIN 11

View full screen / Print PDF » Download PDF ⇩

PDF Transcript

INTRAFUSIN® 11
PATIENT INFORMATION LEAFLET
What you should know about Intrafusin® 11
Please read this carefully before you use this medicine. This leaflet provides some useful
information for you on this medicine. If you have any questions or are not sure about
anything, please ask your doctor or pharmacist (chemist).
Remember this medicine is for you. Only a doctor can prescribe it for you. Never give it to
others. It may harm them even if their symptoms are the same as yours.
The name of your medicine is Intrafusin® 11.
What is in your medicine?
Intrafusin® 11 is a clear, sterile solution of amino acids with electrolytes. Amino acids are
the building blocks the body uses to make protein. Electrolytes are essential for normal body
processes having a variety of functions, for example, sodium and potassium help maintain
normal heart rhythm.
1000 ml of Intrafusin® 11 contains the following:
Isoleucine
Leucine
Lysine-L-glutamate 2H2O
Methionine
Phenylalanine
Threonine
Tryptophan
Valine
Arginine
Histidine
N-Acetyl-L-cysteine
Glycine
Alanine
Glutamic acid
Proline
Serine
N-Acetyl-L-tyrosine
Glycerol-1(2)-dihydrogen phosphate
mixture of disodium salt 5H2O
Potassium hydrogen glutamate H2O
Sodium chloride
Potassium chloride
Citric acid

Ph Eur
Ph Eur
Ph Eur
DAB
Ph Eur
Ph Eur
Ph Eur
Ph Eur
Ph Eur
Ph Eur
Ph Eur
Ph Eur
Ph Eur
DAB

2.10 grams
2.85 grams
7.58 grams
2.70 grams
2.03 grams
2.70 grams
1.05 grams
2.33 grams
6.98 grams
1.73 grams
0.53 grams
7.80 grams
12.97 grams
4.70 grams
7.05 grams
7.05 grams
1.13 grams

FP
Ph Eur
Ph Eur
Ph Eur

6.11 grams
4.06 grams
2.34 grams
1.49 grams
1.15 grams

Ph Eur
Ph Eur

Magnesium chloride 6H2O
Calcium chloride 2H2O

Ph Eur
Ph Eur

This provides the following
electrolytes:
Sodium
Calcium
Potassium
Magnesium
Chloride
Phosphate
Citrate

1.02 grams
0.44 grams

80.0 mmol
3.0 mmol
40.0 mmol
5.0 mmol
76.0 mmol
20.0 mmol
6.0 mmol

These ingredients are dissolved in Water for Injections Ph Eur. Each bottle holds 1000 ml of
solution.
Intrafusin® 11 is one of a group of medicines called intravenous (given into the bloodstream)
amino acid solutions with electrolytes. It gives you some of the goodness you would
normally get from the food in your diet. It is used with other solutions to form a balanced
intravenous feed.
The company responsible for Intrafusin® 11 in the UK (also known as the product licence
holder) is Fresenius Kabi Limited, Cestrian Court, Eastgate Way, Manor Park, Runcorn,
Cheshire, WA7 1NT, UK. The product is made by Baxter Deutschland GmbH, Dr.Wandinger-Str.1, D-94447 Plattling, Germany
What is your medicine for?
Intrafusin® 11 helps provide nourishment straight into your bloodstream when you cannot eat
normally. It gives amino acids which your body will use to make proteins. These will build
and repair parts of the body. It also contains electrolytes which help prevent deficiencies
which would otherwise disrupt normal body functions. It is usually used as part of a
balanced intravenous food diet, together with fat, carbohydrates, salts and vitamins.
Things to remember about Intrafusin® 11
It should not be given to children.
Nothing should be added to Intrafusin® 11 unless it is safe to do so.
Before giving you Intrafusin® 11 - your doctor should know
− Whether you have collapsed with very low blood pressure.
− Whether you have or have had any kidney or liver problems.
− Whether you have or have had high levels of potassium in your blood.

− Whether your body has problems using amino acids or protein.
− Whether you are pregnant, likely to become pregnant or are breast feeding
Your doctor may want to do blood tests to check your vitamin levels before or during
treatment.
How your treatment will be given
Dose:
− The dose is dependent upon your individual needs. The recommended dose of Intrafusin®
11 for adults is between 1-2g of amino acids per kg body weight each day. Another way
of saying this is 1000-2000 ml of Intrafusin® 11 daily for an average sized patient (70 kg).
− For pregnant women and for people who have just had surgery, the dose is 1.6-2.0 g amino
acids per kg body weight each day.
Method:
− Intrafusin® 11 will be given slowly by drip through a small plastic tube, called a catheter,
into your bloodstream. An electronic pump may be used to control the speed of your drip.
− One litre of a solution containing Intrafusin ® 11 should be given over at least 7-8 hours.
The rate of infusion should be carefully controlled in patients who tend to develop high blood
potassium or urea levels.
How often will your medicine be given?
Intrafusin® 11 will usually be given every day until you can start eating again.
How long should you take your medicine for?
As long as it takes for you to start eating normally. This could take some time depending on
your illness.
What you should do in case of overdose
In the extremely unlikely event of overdose either in the hospital or home, tell your doctor or
nurse immediately if you are worried.
What should you do if you miss a dose?
Do not worry, but remember to take the next dose as usual. Do not double the dose next
time.
Sometimes your doctor may tell you to cut short or miss a dose but this will be in your best
interest.

What might happen while you are taking your medicine?
Side effects are not expected with Intrafusin® 11, but too rapid an infusion may result in kidney
problems and nausea in sensitive patients. If you suffer any unwanted effects while taking
Intrafusin® 11 please tell your doctor or pharmacist (chemist).
How should you store your medicine?
• If you are storing Intrafusin® 11, keep it away from light at room temperature (15-25°C).
• The bottle label has an expiry date. Do not use Intrafusin® 11 after this date.
• Do not use the solution if the bottle is leaking.
• Do not use the solution if it is cloudy or has bits in it.
• Do not use the solution if it is an unusual colour - it should be colourless.
• If you do not use all the solution in the bottle, throw the rest of it away. Do not re-use it.

Date of revision: August 2006

PL

08828/0106

Expand Transcript

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Hide