INDEPENDENT PARACETAMOL EXTRA PAIN RELIEF 500MG/65MG TABLETS
3. How to take this medicine
Swallow the tablets whole with water.
Do not chew.
PATIENT INFORMATION LEAFLET
Read all of this leaflet carefully before you
take this medicine because it contains
important information you need to know.
This medicine is available without prescription,
however, you still need to use this product
carefully to get the best results from it.
Keep this leaflet as you may need to read it
again. Ask your pharmacist if you need more
information or advice.
1. What is this medicine and
what is it used for?
This medicine contains:
• paracetamol which is a pain reliever
(analgesic) and helps reduce your
temperature when you have a fever
• caffeine which helps to increase the pain
relief from paracetamol and makes you
These tablets are for the relief of mild to
moderate pain including headache, migraine,
toothache, nerve pain, sore throat and period
pains. They are also for symptomatic relief of
sprains, strains, rheumatic pain, sciatica,
lumbago, fibrositis, muscular aches and pains,
joint swelling and stiffness, flu, feverishness
and feverish colds.
2. Is this medicine suitable
Do not take this medicine if you:
• are allergic to paracetamol, caffeine or
any of the other ingredients
• have high blood pressure or are taking any
medication for high blood pressure, such
as beta blockers
• your heart beat is too fast, too slow or
• are recovering from alcoholism and are
taking the medicine disulfiram
• are taking any medication to treat anxiety,
this includes antidepressants (e.g. lithium
carbonate or monoamine oxidase inhibitors),
anxiolytics or sedatives (e.g. diazepam)
• are currently taking the medicine ephedrine
(a decongestant) or theophylline, which is
used to treat asthma
• are pregnant or breastfeeding.
Please see your doctor or pharmacist
before taking this medicine if you:
• suffer from kidney or liver problems,
including alcoholic liver disease
Adults, the elderly and children over 12
years: 2 tablets every 4 hours as required.
Do not take more than 4 doses (8 tablets) in
any 24 hour period. Do not take more often
than every 4 hours.
If you are taking any of the following
medicines please see your doctor:
• medicines to treat high cholesterol levels
which reduce the amount of fat in the
blood such as colestyramine
• medicines to control feeling sick or being
sick such as metoclopramide or domperidone
• medicines called anti-coagulants, which
are used to thin the blood such as warfarin
or other coumarins - you may take
occasional doses of paracetamol but
should consult your doctor if you need to
take it on a regular basis
• medicines used during hospital tests for
heart conditions such as adenosine and
• medicines used to treat the skin condition
psoriasis, such as methoxsalen
• medicines to treat epilepsy, such as phenytoin
• medicines used to treat thyroid conditions,
such as levothyroxine
• medicines used to treat infections, such as
• Contains paracetamol.
• Do not take anything else containing
paracetamol while taking this medicine.
Do not give to children under 12 years.
Do not take more medicine than the label tells you
to. If you do not get better, talk to your doctor.
Talk to a doctor at once if you take too
much of this medicine even if you feel well.
This is because too much paracetamol
can cause delayed, serious liver damage.
Go to your nearest hospital casualty department.
Take your medicine and this leaflet with you.
If your symptoms continue or your headache
becomes persistent, see your doctor.
4. Possible side effects
Most people do not have any side effects while
taking this medicine. However, if you experience
any of the following side effects, or anything else
unusual happens, stop taking the medicine
immediately, and see your doctor or pharmacist.
Stop taking the medicine and tell your
doctor if you experience:
• allergic reactions which may be severe
such as skin rash, or itching, sometimes
with shortness of breath or swelling of the
mouth, lips, tongue, throat or face.
• breathing problems. These are more likely if
you have experienced them before when
taking other painkillers such as aspirin or
ibuprofen (non-steroidal anti-inflammatories)
• severe rash or peeling of the skin which
may be accompanied by mouth ulcers.
Taking this medicine with food and drink:
Each tablet contains 65 mg of caffeine and up
to 8 tablets (or 520 mg of caffeine) may be
taken per day. If you are also consuming other
medicines or food that contains caffeine (coffee,
tea, cola drinks, chocolate) you may have a high
caffeine intake and might have difficulty sleeping,
start shaking and/or have an uncomfortable
feeling in the chest. You should avoid too
much caffeine in drinks like coffee and tea.
Paracetamol side effects:
Rare side effects are:
• other allergic reactions (e.g. skin rash)
• yellowing of the skin or eyes, pale stools or
upper abdominal pain (these may be signs
of liver problems).
Although the amount of caffeine in a drink of
coffee and tea depends on how they are
made, you can use the table below as a
guide to the amount of caffeine contained
within certain foods and drinks:
Amount* Caffeine content
50 - 100 mg
20 - 73 mg
20 - 73 mg
Up to 20 mg
5 - 20 mg
Your medicine 1 tablet
More rarely, the following side effects
• you may become more prone to bleeding,
bruising, fever and infections, such as sore
throat and ulcers, due to changes in your
Caffeine side effects:
If you do not take more than the recommended
520 mg of caffeine per day side effects are
unlikely, but you must remember to take into
account caffeine from coffee, tea, other
*100 ml is a small cup / glass.
Maximum recommended caffeine intake per
day: 520 mg.
Please turn over ➥
Health Essentials Pain Relief Plus Tablets
medicines, etc. Some people are more sensitive
to caffeine and can get side effects at lower
doses, especially if they have never had caffeine
before or have not had caffeine for some time.
Side effects may include tremor, insomnia,
nervousness, irritability, anxiety, headache,
tinnitus (ringing in the ears), and stomach
complaints (e.g. nausea, vomiting and
diarrhoea). You may also notice palpitations,
changes in heartbeat, an increased need to
pass water, and rapid breathing.
If you experience any caffeine-related side
effects, stop taking all medicines containing
caffeine, including this medicine and stop
consuming food that contains caffeine
(coffee, tea, cola drinks, and chocolate).
If you stop taking caffeine after regular use:
There are some people who may experience
unwanted side effects when they stop taking
tablets or foods containing caffeine after regular
use. The most common effect is headache but
also tiredness and feeling less alert can occur.
These effects are temporary and may last up
to a week but to minimize these effects it is
best to gradually reduce caffeine intake.
Reporting of side effects
If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible
side effects not listed in this leaflet. You can
also report side effects directly via the Yellow
Card Scheme at: www.mhra.gov.uk/yellowcard.
By reporting side effects you can help provide
more information on the safety of this medicine.
5. How to store your medicine
Keep all medicines out of the sight and
reach of children.
Do not use this medicine after the expiry date
printed on the pack.
6. What is in this medicine?
Each tablet contains the active ingredients:
paracetamol 500 mg and caffeine 65 mg.
The other ingredients are: povidone, maize
starch, methylcellulose, talc, calcium stearate
and purified water.
This product is available in pack sizes of 16
and 32 tablets.
7. Who makes this medicine?
The Marketing Authorisation holder and
manufacturer is Wrafton Laboratories Limited,
Braunton, Devon, EX33 2DL, UK.
Text revised: March 2014.
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.