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Active substance(s): ACETYLCYSTEINE

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Read all of this leaflet carefully before you start using this medicine

Laetus Pharma Code (mini):
Height: 7 mm
Reading: left to right

Package Leaflet - Information for the User




Laetus Pharma Code (mini):
Height: 7 mm
Reading: left to right

• Keep this leaflet. You may need to read it again.

• If you have any further questions, ask your doctor or your pharmacist.

• This medicine has been prescribed for you. Do not pass it on to others.
It may harm them, even if their symptoms are the same as yours.

• If any of the side effects get serious, or if you notice any side effects
not listed in this leaflet, please tell your doctor or pharmacist.

5% w/v eye drops, solution

1. What ILUBE is and what it is used for
2. Before you use ILUBE
3. How to use ILUBE
4. Possible side effects
5. How to store ILUBE
6. Further information


ILUBE is a solution that acts as an artificial tear.



It is used to provide relief for dry eyes conditions which are associated with a lack of
tears or abnormal tear production. ILUBE works by reducing the stickiness of tears
and lubricating dry eyes to relieve discomfort.


Do not use ILUBE...
• If you are allergic to acetylcysteine or any of the other ingredients listed in
section 6.
Ask your doctor for advice.

Driving and using machines
Your vision may be blurred after using ILUBE. Do not drive or use any machines
unless your vision is clear.

Using other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other
medicines, including medicines obtained without a prescription.

Pregnancy and breast-feeding
If you are pregnant or might get pregnant, or if you are breast-feeding, talk to your
doctor before you use ILUBE.


Important information if you wear Contact Lenses
Do not use the drops while wearing contact lenses. Wait at least 15 minutes after
use before putting your lenses back in. There is a preservative in ILUBE (benzalkonium
chloride) that can discolour soft contact lenses.


The usual dose
The usual dose is 1 or 2 drops into the affected eye 3 or 4 times daily or as advised
by your doctor.
Always use ILUBE exactly as your doctor has told you. You should check with your
doctor or pharmacist if you are not sure.

How to use
• Wash your hands before you start.
• Take the bottle, lift the side of the top as shown (see
diagram A). Remove the yellow plastic disc and the
adjoining aluminium ring.


• Remove the black rubber bung.
• Open the plastic bag and take out the plastic dropper.
• Push the plastic dropper onto the glass bottle. Unscrew
the plastic cap as shown in diagram B.

Continued over ►



HOW TO USE ILUBE (continued)

• Tilt your head back.
• Bring the dropper close to the eye. Do this in front of a
mirror if it helps.


• Close your eye for about 30 seconds (Diagram E).
• If you use drops in both eyes, repeat the steps for your
other eye. Screw the cap on the plastic dropper.


• Do not touch your eye or eyelid, surrounding areas or
other surfaces with the dropper. It could contaminate the
• Pull down your lower eyelid with a finger (Diagram C), until
there is a ‘pocket’ between the eyelid and your eye. Press
lightly on the middle of the plastic dropper.


• Put one or two drops, as directed, in your eye (Diagram D).

• If a drop misses your eye, try again.
• If you forget to use ILUBE, do not worry, just use it as soon as you remember.
Do not take a double dose to make up.
• If you use more ILUBE than you should, close your eyes and rinse off any excess
ILUBE with warm water.


• You may experience some or all of the following effects in your eye(s):
Itching, redness, irritation.
If any of the side effects get serious, or you notice any side effects not listed in this
leaflet, tell your doctor or pharmacist.
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible
side effects not listed in this leaflet. You can also report side effects directly via the national
reporting system:

United Kingdom
Yellow Card Scheme
HPRA Pharmacovigilance
Earlsfort Terrace, IRL - Dublin 2
Tel: +353 1 6764971; Fax: +353 1 6762517
By reporting side effects you can help provide more information on the safety of this medicine.


• Keep out of the reach and sight of children.
• Do not store above 25°C.
• Keep the bottle tightly closed.
• Keep in the outer carton and protect from light.
• Do not use the drops after the expiry date (marked ‘Exp’) on the bottle and the
carton. The expiry date refers to the last day of that month.


If you have any further questions on the use of ILUBE, ask your doctor or pharmacist.


Like all medicines, ILUBE can cause side effects, although not everybody gets them.


• If the contents of the bottle are swallowed, tell your doctor or the casualty
department of a hospital immediately.

• Stop using the bottle 4 weeks after first opening, to prevent infections.
• Medicines should not be disposed of via waste water or household waste. Ask your
pharmacist how to dispose of medicines no longer required. These measures will help to
protect the environment.
• Do not pass this medicine on to others. It may harm them even if their symptoms are
the same as yours.


What ILUBE contains

What ILUBE looks like and contents of the pack

• The active substance is acetylcysteine 50 mg/ml (5 % w/v).
• The other ingredients are hypromellose, disodium edetate, benzalkonium chloride,
sodium hydroxide and purified water.

ILUBE is a clear, colourless liquid supplied in a 10 ml glass bottle. The carton also contains
a white plastic dropper with a screw cap packed separately.

Marketing authorisation holder:


Moorfields Eye Hospital NHS Foundation Trust trading as Moorfields Pharmaceuticals,
25 Provost Street, London, N1 7NH, United Kingdom.

Laboratories Pharmaster, Z.I. Krafft, F-67150 Erstein, France.
This leaflet was last approved in October 2015.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.