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IBUPROFEN AND CODEINE 200MG/12.8MG FILM-COATED TABLETS

Active substance(s): CODEINE PHOSPHATE HEMIHYDRATE / IBUPROFEN

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Transcript
Corticosteroids (used for many conditions such as
pain, swelling, allergy, asthma, rheumatism and skin
problems)
● Lithium (for bipolar disorder)
● Methotrexate (for cancer, psoriasis, rheumatism,
Crohn’s disease)
● Zidovudine (for HIV infection)
● Quinolone antibiotics (for infections)
● Medicines for depression (including SSRIs and MAOIs)
● Ciclosporin or tacrolimus (given after transplant surgery,
or for psoriasis or rheumatism)
Some other medicines may also affect or be affected
by the treatment of Ibuprofen and Codeine tablets.
You should therefore always seek the advice of your
doctor or pharmacist before you use this medicine
with any other medicines, including herbal and
homeopathic remedies.


This medicine is available without prescription to treat
minor conditions. However, you still need to take it
carefully to get the best results from it.
● This medicine can only be used for the short term
treatment of acute moderate pain such as
headaches, rheumatic and muscular pain,
backache, migraine, period pain, dental pain and
neuralgia that is not relieved by aspirin, ibuprofen
or paracetamol alone
● This medicine should only be taken when necessary
● You should only take this product for a
maximum of 3 days at a time. If you need to
take it for longer than 3 days you should see your
doctor or pharmacist for advice
● This medicine contains codeine which can
cause addiction if you take it continuously for
more than 3 days. This can give you withdrawal
symptoms from the medicine when you stop taking it
● If you take this medicine for headaches for
more than 3 days it can make them worse
● Keep this leaflet, you may need to read it again
● Ask your pharmacist if you need more
information or advice

What this medicine is for

This medicine can be used for the short term treatment
of acute moderate pain such as headaches, rheumatic
and muscular pain, backache, migraine, period pain,
dental pain and neuralgia that is not relieved by aspirin,
ibuprofen or paracetamol alone.
This medicine contains Codeine. Codeine belongs to a
group of medicines called opioid analgesics which act
to relieve pain.
This codeine-containing medicine can be used in
adults and children aged 12 years and over.
This medicine also contains ibuprofen. Ibuprofen, a
non-steroidal anti-inflammatory medicine (NSAID), also
acts to reduce swelling (inflammation).

Before you take this medicine

This medicine contains codeine which can cause
addiction (physiological and psychological
dependence) if you take it continuously for more than 3
days. This can give you withdrawal symptoms from the
medicine (such as restlessness and irritability) when you
stop taking it. If you find you need to take this medicine
all the time, it is important to talk to your doctor
● If you take a painkiller for headaches for
more than 3 days it can make them worse
This medicine can be taken by adults and children of
12 years and over. However, some people should not
take this medicine or should seek the advice of their
pharmacist or doctor first.


Do not take:

For pain relief in children and adolescents (0-18
years of age) after removal of their tonsils or
adenoids due to obstructive sleep apnoea syndrome
● If you know that you metabolise very rapidly codeine
into morphine
● If you have a stomach ulcer, perforation or
bleeding, or have had one twice or more in the past
If you have had perforation or a bleeding
stomach after taking a non-steroidal antiinflammatory medicine (you may have been sick and it
contained blood or dark particles that look like coffee
grounds, passed blood in your stools or passed black
tarry stools)
● If you are allergic to ibuprofen, codeine or any other
ingredients of the product, aspirin or other
non-steroidal anti-inflammatory medicines (you have
ever had asthma, runny nose, itchy skin or swelling of
the lips, face or throat after taking these medicines)
● If you are taking aspirin with a daily dose above
75 mg, or other non-steroidal anti-inflammatory
medicines
● If you have severe heart, kidney or liver failure
● If you have difficulty breathing or breathing
problems
● If you have constipation on a regular basis or are
continually constipated
● If you are pregnant, and in the last 3 months of
pregnancy
● If you are breastfeeding (see “Other important
information”)


Talk to your pharmacist or doctor:

If you have asthma, a history of asthma or other
allergic disease, bowl problems or Crohn’s disease
● If you have other kidney, heart or liver problems (see
“Do not take”)
● If you have a connective tissue disorder such as SLE
(Systematic Lupus Erythematosus)
● If you have low blood pressure or an underactive
thyroid
● If you have a head injury or a condition where there is
raised pressure in the head
● If you are taking monoamine oxidase inhibitors (MAOIs
for depression), or have taken them in the last 14 days


If you are elderly – you may get more side effects (see
back of the leaflet)
● If you are taking any other painkillers or receiving
regular treatment from your doctor
● If you have had heart problems including heart failure,
angina (chest pain), or if you have had a heart attack,
bypass surgery, peripheral artery disease (poor
circulation in the legs or feet due to narrow or blocked
arteries), or any kind of stroke (including ‘mini-stroke’'
or transient ischaemic attack “TIA”). – see 'Risk of
heart attack or stroke' below
● If you have high blood pressure, diabetes, high
cholesterol, have a family history of heart disease or
stroke, or if you are a smoker.
● If you are pregnant, and in the first 6 months of
pregnancy


How to take this medicine

Check the foil is not broken before use. If it is,
do not take that tablet.

Other important information

Codeine is transformed to morphine in the liver by an
enzyme. Morphine is a substance that produces pain
relief. Some people have a variation of this enzyme
and this can affect people in different ways. In some
people, morphine is not produced or produced in very
small quantities, and will not provide enough pain
relief. Other people are more likely to get serious side
effects because a very high amount of morphine is
produced. If you notice any of the following side
effects, you must stop taking this medicine and seek
immediate medical advice: slow or shallow breathing,
confusion, sleepiness, small pupils, feeling or being
sick, constipation, lack of appetite.
Use in children and adolescents after surgery:
Codeine should not be used for pain relief in children
and adolescents after removal of their tonsils or
adenoids due to obstructive sleep apnoea syndrome.
Use in children with breathing problems: Codeine
is not recommended in children with breathing
problems, since the symptoms of morphine toxicity
may be worse in these children.
Risk of heart attack or stroke:
Anti-inflammatory/pain-killer medicines like ibuprofen
may be associated with a small increased risk of heart
attack or stroke, particularly when used at high doses.
Do not exceed the recommended dose or duration of
treatment.
Pregnancy: During the last 3 months of pregnancy do
not take this medicine. During the first 6 months of
pregnancy talk to your pharmacist or doctor.
Breastfeeding: Do not take codeine while you are
breastfeeding. Codeine and morphine passes into
breast milk.
Women of childbearing age: If you take this
medicine, it may reduce your ability to become
pregnant. This effect will be reversed when you stop
taking the medicine.
Do not drink alcohol (wine, beer, sprits) whilst
taking this medicine. Alcohol may make you feel more
drowsy.
Driving and using machines: This medicine can
affect your ability to drive or use machines as it may
make you feel sleepy or dizzy.
● Do not drive or use machines while taking this
medicine until you are sure you are not affected
● It is an offence to drive if this medicine affects your
ability to drive
● However, you would not be committing an offence if:
- The medicine has been prescribed to treat a medical
or dental problem and
- You have taken it according to the instructions given
by the prescriber or in the information provided with
the medicine and
- It was not affecting your ability to drive safely
Talk to your doctor or pharmacist if you are not sure
whether it is safe for you to drive while taking this
medicine.

If you take other medicines

Before you take these tablets, make sure that you tell
your doctor or pharmacist about ANY other medicines
you might be using at the same time. Ibuprofen and
Codeine tablets may affect or be affected by some
other medicines. For example:
● Other painkillers (including NSAIDs)
● Aspirin 75 mg (to prevent heart attacks or strokes)
– the protection may be reduced when you take
ibuprofen
● Medicines that are anti-coagulants (i.e thin
blood/prevent clotting e.g. aspirin/acetylsalicylic acid,
warfarin, ticlopidine)
● Mifepristone (for termination of pregnancy) –
do not take ibuprofen if you have taken mifepristone in
the last 12 days
● Water tablets (diuretics)
● Medicines that reduce high blood pressure
(ACE-inhibitors such as captopril, beta-blockers such
as atenolol medicines, angiotensin-II receptor
antagonists such as losartan)
● Medicines for heart problems

If you get any of the following side effects see
your pharmacist or doctor:
● Feeling sick or being sick
● Headache, blurred vision, drowsiness - do not drive or
use machines if you feel drowsy or have blurred vision
● High blood pressure, heart failure (you may be tired,
have difficulty breathing or swollen legs)
● Fluid retention, which may cause swelling of the limbs
● Slow or shallow breathing, problems clearing catarrh or
phlegm from the chest
● Very rarely, yellowing of the skin or eyes, pale stools or
upper abdominal pain (these may be signs of liver
problems)
● Swelling or ulcers of the stomach or mouth lining,
constipation
● Rarely, diarrhoea, wind, worsening of colitis or Crohn’s
disease
● Very rarely, tiredness or severe exhaustion, changes in
the blood which may cause unusual bruising or
unexplained bleeding and an increase in the number of
infections that you get (e.g. sore throats, mouth ulcers,
flu-like symptoms including fever)
● A small increased risk of heart attack or stroke
if you take large amounts for a long time
If any side effect becomes severe, or you notice
any side effect not listed here, please tell your
pharmacist or doctor.

Reporting of side effects

If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report side
effects directly via the Yellow Card Scheme at:
www.mhra.gov.uk/yellowcard. By reporting side effects
you can help provide more information on the safety of
this medicine.

How do I know if I am addicted?

Swallow each table with water.
Do not take for more than 3 days. If you need to
use this medicine for more than 3 days you must
speak to your doctor or pharmacist for advice.
Do not give to children under 12 years, due to the risk
of severe breathing problems.
Do not take more than the amount recommended
above.
If you forget to take the tablets, take them as soon as
you remember. Do not make up for the missed tablets
by taking more than 2 tablets at a time.
If your symptoms worsen at any time, or do not go
away within 3 days, you must speak to your doctor or
pharmacist.
If you take too many tablets: Talk to a doctor
straight away. Take your medicine and this leaflet
with you.

Possible withdrawal effects when stopping
treatment

This medicine contains codeine and can cause
addiction If you take it continuously for more than 3
days. When you stop taking it you may get withdrawal
symptoms. You should talk to your doctor or
pharmacist if you think you are suffering from
withdrawal symptoms.

Possible side effects

Most people will not have problems but some people
may have side effects when taking this medicine. If you
are elderly you may be more likely to have some of
these side effects.
If you have any unwanted side effects you should seek
advice from your doctor, pharmacist or other
healthcare professional.
If you get any of these serious side effects,
stop taking the tablets. See a doctor at once:
● You are sick and it contains blood or dark
particles that look like coffee grounds
● Pass blood in your stools or pass black tarry stools
● Stomach problems including pain, indigestion
or heartburn
● Unexplained wheezing (asthma), worsening or existing
asthma, difficulty in breathing, swelling of the face,
tongue, neck or throat, fast heart rate, feeling faint or
dizzy or collapse (severe allergic reactions)
● Allergic skin reactions such as itchy, red, raised rash
(which can sometimes be severe and include peeling,
blistering and lesions of the skin)
● Meningitis (e.g. stiff neck, fever, disorientation)
● Kidney problems, which may lead to kidney failure (you
may pass more or less urine, have blood in the urine
or cloudy urine, or feel breathless, very tired or weak,
have no appetite, or have swollen ankles)

If you take the medicine according to the instructions
on the pack it is unlikely that you will become addicted
to the medicine. However, if the following apply to
you it is important that you talk to your doctor:
● You need to take the medicine for longer periods
of time
● You need to take more than the recommended
amount
● When you stop taking the medicine you feel very
unwell but you feel better if you start taking the
medicine again

How to store this medicine

These film-coated tablets do not require any special
storage conditions. Keep this medicine in a safe place
out of the sight and reach of children, preferably in a
locked cupboard.
Use by the date on the foil or end flap of the carton.
After this date return any unused product to your
nearest pharmacy for safe disposal.

What is in this medicine

Each film-coated tablet contains Codeine Phosphate
Hemihydrate 12.8 mg, Ibuprofen 200 mg, which are the
active ingredients.
As well as the active ingredients, the film-coated
tablets also contain microcrystalline cellulose, sodium
starch glycolate, pregelatinised maize starch,
hypromellose. The tablet coating contains
hypromellose, titanium dioxide (E171), talc.
The pack contains 16 or 32 white capsule-shaped
tablets embossed with l+.

Who makes this medicine

Manufactured for Almus Pharmaceuticals Ltd.,
Chessington, KT9 1SN by
Custom Pharmaceuticals Ltd Conway Street Hove
East Sussex BN3 3LW, UK
MA holder: BCM, Nottingham, NG2 3AA, UK
Leaflet prepared December 2015
If you would like any further information about this
medicine, please contact Almus Pharmaceuticals
Ltd., Chessington, KT9 1SN

Other formats

To request a copy of this leaflet in Braille, large print or
audio please call free of charge:

0800 198 5000 (UK only)

Please be ready to give the following information:
Product name: Ibuprofen and Codeine
200 mg/12.8 mg Tablets
Reference Number: 00014/0662
This is a service provided by the Royal
National Institute of Blind People.

AL0071/Lt8 AL0070/Lt8
PM20491

Lithium (for bipolar disorder)
Methotrexate (for cancer, psoriasis, rheumatism,
Crohn’s disease)
● Zidovudine (for HIV infection)
● Quinolone antibiotics (for infections)
● Medicines for depression (including SSRIs and MAOIs)
● Ciclosporin or tacrolimus (given after transplant surgery,
or for psoriasis or rheumatism)
Some other medicines may also affect or be affected
by the treatment of Ibuprofen and Codeine tablets.
You should therefore always seek the advice of your
doctor or pharmacist before you use this medicine
with any other medicines, including herbal and
homeopathic remedies.



This medicine is available without prescription to treat
minor conditions. However, you still need to take it
carefully to get the best results from it.
● This medicine can only be used for the short term
treatment of acute moderate pain such as
headaches, rheumatic and muscular pain,
backache, migraine, period pain, dental pain and
neuralgia that is not relieved by aspirin, ibuprofen
or paracetamol alone
● This medicine should only be taken when necessary
● You should only take this product for a
maximum of 3 days at a time. If you need to
take it for longer than 3 days you should see your
doctor or pharmacist for advice
● This medicine contains codeine which can
cause addiction if you take it continuously for
more than 3 days. This can give you withdrawal
symptoms from the medicine when you stop taking it
● If you take this medicine for headaches for
more than 3 days it can make them worse
● Keep this leaflet, you may need to read it again
● Ask your pharmacist if you need more
information or advice

Talk to your pharmacist or doctor:

If you have asthma, a history of asthma or other
allergic disease, bowl problems or Crohn’s disease
● If you have other kidney, heart or liver problems (see
“Do not take”)
● If you have a connective tissue disorder such as SLE
(Systematic Lupus Erythematosus)
● If you have low blood pressure or an underactive
thyroid
● If you have a head injury or a condition where there is
raised pressure in the head
● If you are taking monoamine oxidase inhibitors (MAOIs
for depression), or have taken them in the last 14 days
● If you are elderly – you may get more side effects (see
back of the leaflet)
● If you are taking any other painkillers or receiving
regular treatment from your doctor
● If you have had heart problems including heart failure,
angina (chest pain), or if you have had a heart attack,
bypass surgery, peripheral artery disease (poor
circulation in the legs or feet due to narrow or blocked
arteries), or any kind of stroke (including ‘mini-stroke’
or transient ischaemic attack “TIA”). - see “Risk of
heart attack or stroke” below
What this medicine is for
● If you have high blood pressure, diabetes, high
This medicine can be used for the short term treatment
cholesterol, have a family history of heart disease or
of acute moderate pain such as headaches, rheumatic
stroke, or if you are a smoker.
and muscular pain, backache, migraine, period pain,
● If you are pregnant, and in the first 6 months of
dental pain and neuralgia that is not relieved by aspirin,
pregnancy
ibuprofen or paracetamol alone.
This medicine contains Codeine. Codeine belongs to a
Other important information
group of medicines called opioid analgesics which act
Codeine is transformed to morphine in the liver by an
to relieve pain.
enzyme. Morphine is a substance that produces pain
This codeine-containing medicine can be used in
relief. Some people have a variation of this enzyme
adults and children aged 12 years and over.
and this can affect people in different ways. In some
This medicine also contains ibuprofen. Ibuprofen, a
people, morphine is not produced or produced in very
non-steroidal anti-inflammatory medicine (NSAID), also
small quantities, and will not provide enough pain
acts to reduce swelling (inflammation).
relief. Other people are more likely to get serious side
effects because a very high amount of morphine is
Before you take this medicine
produced. If you notice any of the following side
● This medicine contains codeine which can cause
effects, you must stop taking this medicine and seek
addiction (physiological and psychological
immediate medical advice: slow or shallow breathing,
dependence) if you take it continuously for more than 3
confusion, sleepiness, small pupils, feeling or being
days. This can give you withdrawal symptoms from the
sick, constipation, lack of appetite.
medicine (such as restlessness and irritability) when you
Use in children and adolescents after surgery:
stop taking it. If you find you need to take this medicine
Codeine should not be used for pain relief in children
all the time, it is important to talk to your doctor
and adolescents after removal of their tonsils or
● If you take a painkiller for headaches for
adenoids due to obstructive sleep apnoea syndrome.
more than 3 days it can make them worse
Use in children with breathing problems: Codeine
This medicine can be taken by adults and children of
is not recommended in children with breathing
12 years and over. However, some people should not
problems, since the symptoms of morphine toxicity
take this medicine or should seek the advice of their
may be worse in these children.
pharmacist or doctor first.
Risk of heart attack or stroke:
Anti-inflammatory/pain-killer medicines like ibuprofen
Do not take:
may be associated with a small increased risk of heart
● For pain relief in children and adolescents (0-18
attack or stroke, particularly when used at high doses.
years of age) after removal of their tonsils or
Do not exceed the recommended dose or duration of
adenoids due to obstructive sleep apnoea syndrome
treatment.
● If you know that you metabolise very rapidly codeine
Pregnancy: During the last 3 months of pregnancy do
into morphine
not take this medicine. During the first 6 months of
● If you have a stomach ulcer, perforation or
pregnancy talk to your pharmacist or doctor.
bleeding, or have had one twice or more in the past
Breastfeeding: Do not take codeine while you are
If you have had perforation or a bleeding
breastfeeding. Codeine and morphine passes into
stomach after taking a non-steroidal antibreast milk.
inflammatory medicine (you may have been sick and it
Women of childbearing age: If you take this
contained blood or dark particles that look like coffee
medicine, it may reduce your ability to become
grounds, passed blood in your stools or passed black
pregnant. This effect will be reversed when you stop
tarry stools)
taking the medicine.
● If you are allergic to ibuprofen, codeine or any other
Do not drink alcohol (wine, beer, sprits) whilst
ingredients of the product, aspirin or other
taking this medicine. Alcohol may make you feel more
non-steroidal anti-inflammatory medicines (you have
drowsy.
ever had asthma, runny nose, itchy skin or swelling of
Driving and using machines: This medicine can
the lips, face or throat after taking these medicines)
affect your ability to drive or use machines as it may
● If you are taking aspirin with a daily dose above
make you feel sleepy or dizzy.
75 mg, or other non-steroidal anti-inflammatory
● Do not drive or use machines while taking this
medicines
● If you have severe heart, kidney or liver failure
medicine until you are sure you are not affected
● If you have difficulty breathing or breathing
● It is an offence to drive if this medicine affects your
problems
ability to drive
● If you have constipation on a regular basis or are
● However, you would not be committing an offence if:
continually constipated
- The medicine has been prescribed to treat a medical
● If you are pregnant, and in the last 3 months of
or dental problem and
pregnancy
- You have taken it according to the instructions given
● If you are breastfeeding (see “Other important
by the prescriber or in the information provided with
information”)
the medicine and
- It was not affecting your ability to drive safely


How to take this medicine

Check the foil is not broken before use. If it is,
do not take that tablet.

If you get any of the following side effects see
your pharmacist or doctor:
● Feeling sick or being sick
● Headache, blurred vision, drowsiness - do not drive or
use machines if you feel drowsy or have blurred vision
● High blood pressure, heart failure (you may be tired,
have difficulty breathing or swollen legs)
● Fluid retention, which may cause swelling of the limbs
● Slow or shallow breathing, problems clearing catarrh or
phlegm from the chest
● Very rarely, yellowing of the skin or eyes, pale stools or
upper abdominal pain (these may be signs of liver
problems)
● Swelling or ulcers of the stomach or mouth lining,
constipation
● Rarely, diarrhoea, wind, worsening of colitis or Crohn’s
disease
● Very rarely, tiredness or severe exhaustion, changes in
the blood which may cause unusual bruising or
unexplained bleeding and an increase in the number of
infections that you get (e.g. sore throats, mouth ulcers,
flu-like symptoms including fever)
● A small increased risk of heart attack or stroke
if you take large amounts for a long time
If any side effect becomes severe, or you notice
any side effect not listed here, please tell your
pharmacist or doctor.

Reporting of side effects

If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report side
effects directly via the Yellow Card Scheme at:
www.mhra.gov.uk/yellowcard. By reporting side effects
you can help provide more information on the safety of
this medicine.
Swallow each table with water.
Do not take for more than 3 days. If you need to
use this medicine for more than 3 days you must
speak to your doctor or pharmacist for advice.
Do not give to children under 12 years, due to the risk
of severe breathing problems.
Do not take more than the amount recommended
above.
If you forget to take the tablets, take them as soon as
you remember. Do not make up for the missed tablets
by taking more than 2 tablets at a time.
If your symptoms worsen at any time, or do not go
away within 3 days, you must speak to your doctor or
pharmacist.
If you take too many tablets: Talk to a doctor
straight away. Take your medicine and this leaflet
with you.

Possible withdrawal effects when stopping
treatment

This medicine contains codeine and can cause
addiction If you take it continuously for more than 3
days. When you stop taking it you may get withdrawal
symptoms. You should talk to your doctor or
pharmacist if you think you are suffering from
withdrawal symptoms.

Possible side effects

Most people will not have problems but some people
may have side effects when taking this medicine. If you
are elderly you may be more likely to have some of
these side effects.
If you have any unwanted side effects you should seek
advice from your doctor, pharmacist or other
healthcare professional.
If you get any of these serious side effects,
stop taking the tablets. See a doctor at once:
● You are sick and it contains blood or dark
particles that look like coffee grounds
● Pass blood in your stools or pass black tarry stools
● Stomach problems including pain, indigestion
or heartburn
● Unexplained wheezing (asthma), worsening or existing
asthma, difficulty in breathing, swelling of the face,
tongue, neck or throat, fast heart rate, feeling faint or
dizzy or collapse (severe allergic reactions)
● Allergic skin reactions such as itchy, red, raised rash
(which can sometimes be severe and include peeling,
blistering and lesions of the skin)
● Meningitis (e.g. stiff neck, fever, disorientation)
● Kidney problems, which may lead to kidney failure (you
may pass more or less urine, have blood in the urine
or cloudy urine, or feel breathless, very tired or weak,
have no appetite, or have swollen ankles)

How do I know if I am addicted?

If you take the medicine according to the instructions
on the pack it is unlikely that you will become addicted
to the medicine. However, if the following apply to
you it is important that you talk to your doctor:
● You need to take the medicine for longer periods
of time
● You need to take more than the recommended
amount
● When you stop taking the medicine you feel very
unwell but you feel better if you start taking the
medicine again

How to store this medicine

These film-coated tablets do not require any special
storage conditions. Keep this medicine in a safe place
out of the sight and reach of children, preferably in a
locked cupboard.
Use by the date on the foil or end flap of the carton.
After this date return any unused product to your
nearest pharmacy for safe disposal.

What is in this medicine

Each film-coated tablet contains Codeine Phosphate
Hemihydrate 12.8 mg, Ibuprofen 200 mg, which are the
active ingredients.
As well as the active ingredients, the film-coated
tablets also contain microcrystalline cellulose, sodium
starch glycolate, pregelatinised maize starch,
hypromellose. The tablet coating contains
hypromellose, titanium dioxide (E171), talc.
The pack contains 16 or 32 white capsule-shaped
tablets embossed with l+.

Who makes this medicine

Manufactured for Almus Pharmaceuticals Ltd.,
Chessington, KT9 1SN by Famar SA Anthoussa
Attiki 15344 Greece
MA holder: BCM, Nottingham, NG2 3AA, UK
Leaflet prepared December 2015
If you would like any further information about this
medicine, please contact Almus Pharmaceuticals
Ltd., Chessington, KT9 1SN

Other formats

To request a copy of this leaflet in Braille, large print or
audio please call free of charge:

0800 198 5000 (UK only)

Please be ready to give the following information:
Product name: Ibuprofen and Codeine
200 mg/12.8 mg Tablets
Reference Number: 00014/0662
This is a service provided by the Royal
National Institute of Blind People.

Talk to your doctor or pharmacist if you are not sure
whether it is safe for you to drive while taking this
medicine.

If you take other medicines

Before you take these tablets, make sure that you tell
your doctor or pharmacist about ANY other medicines
you might be using at the same time. Ibuprofen and
Codeine tablets may affect or be affected by some
other medicines. For example:
● Other painkillers (including NSAIDs)
● Aspirin 75 mg (to prevent heart attacks or strokes)
– the protection may be reduced when you take
ibuprofen
● Medicines that are anti-coagulants (i.e thin
blood/prevent clotting e.g. aspirin/acetylsalicylic acid,
warfarin, ticlopidine)
● Mifepristone (for termination of pregnancy) –
do not take ibuprofen if you have taken mifepristone in
the last 12 days
● Water tablets (diuretics)
● Medicines that reduce high blood pressure
(ACE-inhibitors such as captopril, beta-blockers such
as atenolol medicines, angiotensin-II receptor
antagonists such as losartan)
● Medicines for heart problems
● Corticosteroids (used for many conditions such as
pain, swelling, allergy, asthma, rheumatism and skin
problems)

AL0071/Lt9
AL0070/Lt9
31023032

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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