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Patient Information Leaflet

Half Securon® SR Tablets
(verapamil hydrochloride)

Leaflet contents:
1. What is Half Securon SR and what is it used for?
2. What should you know before taking your tablets?
3. How should you take your tablets?
4. Possible side effects.
5. How should you store your tablets?
6. Further information
1. What is Half Securon SR and what is it used


Half Securon SR belongs to a group of medicines
called calcium channel blockers. Calcium channel
blockers change the amount of calcium getting into the
muscle cells in your heart and blood vessels. This can
change the strength and speed with which your heart
beats. It also opens up the blood vessels so blood can
be pumped around the body more easily. This helps
more oxygen to get to your heart muscle and can lower
your blood pressure.

Read all of this leaflet carefully
before you start taking this

Half Securon SR is used to treat hypertension (high
blood pressure) and to prevent angina (chest pain)
attacks. The tablets may also be prescribed following a
heart attack, to prevent another attack occurring.

The name of your medicine is Half
Securon SR Tablets but will be
referred to as Half Securon SR
throughout this leaflet. This leaflet
also contains information about
Securon SR 240mg Tablets

Keep this leaflet as you may
need to read it again
This leaflet provides a summary
of the information currently
available about Half Securon
For further information or
advice ask your doctor or
This medicine is for you only
and should never be given to
anyone else, even if they
appear to have the same
symptoms as you
Tell your doctor or pharmacist if
you experience any side effects

The active ingredient in Half Securon SR is verapamil
2. What should you know before taking your
If the answer to any of the following
questions is 'YES' please tell your doctor or
pharmacist BEFORE taking any tablets:
Are you sensitive (allergic) to verapamil or any of the
ingredients in the tablets? (See Section 6).
Are you pregnant or planning to become pregnant,
or are you breast-feeding?
Do you have very low blood pressure?
Do you have or have you ever suffered from heart
problems such as heart failure?
Do you have an abnormally slow or irregular heart
Have you recently had a heart attack?
Do you have liver or kidney problems?

Do you have or have you ever suffered from heart
problems such as heart failure or the heart condition
called Wolff-Parkinson-White syndrome?
Do you have a condition where the nerve to muscle
transmission is affected e.g. myasthenia gravis,
Lambert-Eaton syndrome, advanced Duchenne
muscular dystrophy?
Are you being treated with ivabradine (for heart
Taking other medicines.
Please tell your doctor or pharmacist if you are
taking any medicines with or without a prescription
or have recently taken any of the following
beta-blockers used to treat high blood pressure and
heart conditions (these include atenolol, propranolol
and metoprolol)
alpha-blockers used to treat high blood pressure
and heart conditions (these include prazosin and
diuretics (also called ‘water pills’)
medicines known as ‘statins’ such as atorvastatin,
lovastatin, simvastatin used to lower cholesterol
any other medicine for high blood pressure or an
abnormal heart beat (arrhythmia) such as quinidine,
flecainide, digoxin and digitoxin
dabigatran (medicine to prevent the formation of
blood clots)
medicines containing ivabradine for the treatment of
certain heart diseases
medicines used to treat depression (including the
herbal product St John's Wort), anxiety or psychosis.
These may include imipramine, buspirone and
medicines known as immunosuppressants such as
ciclosporin, sirolimus, everolimus and tacrolimus
These are used to prevent organ transplant rejection
glibenclamide, used to treat certain types of
aspirin, a non-steroidal anti-inflammatory painkiller
(NSAID) used to relieve pain and reduce fever
almotriptan, used to treat migraine
midazolam, used as a sedative or anaesthetic
theophylline, used to treat asthma
doxorubicin, an anti-cancer medicine

cimetidine, used to treat indigestion or stomach
carbamazepine, phenytoin or phenobarbital
(phenobarbitone). These medicines are used as
rifampicin, used to treat tuberculosis and other types
of infection
ritonavir, used to treat HIV
erythromycin, clarithromycin and telithromycin, used
to treat certain types of infection
colchicine or sulfinpyrazone, used to treat gout.
Tell your surgeon or dentist that you are taking Half
Securon SR if surgery is planned as it may affect the
anaesthetic used.
Driving and operating machines
Do NOT drive, operate machinery or do
anything that requires you to be alert, until
you know how the tablets affect you.

Half Securon SR can make some people feel
dizzy, especially when they first start to take
the tablets.
Other important information
Do NOT drink grapefruit juice whilst taking your tablets
as it can affect the absorption of this medicine. This
does not occur with other fruit juices such as orange,
apple or tomato juice.
Drinking alcohol
Half Securon SR will increase the time your body takes
to get rid of alcohol. This means that you may not have
to drink as much for your blood alcohol levels to be
above the legal limit to drive. It will also take you longer
to sober up.
Taking Half Securon SR with food and drink
Your tablets can be taken with a glass of water to help
you swallow them. It does not matter if you have eaten,
so they can be taken with or without food.
Pregnancy and breast-feeding
Please discuss with your doctor if you are pregnant,
planning to become pregnant or are breast-feeding.

3. How should you take your tablets?
ALWAYS take your tablets exactly as your doctor has
told you. If you are not sure refer to the label on the
carton or check with your doctor or pharmacist.
TAKE YOUR TABLETS with a glass of
water. You should swallow the tablets
without chewing or crushing them. It does
not matter if you have not eaten.
The number of tablets that you will need to take will
depend on what you are being treated for:
Hypertension (high blood pressure)
The usual dose is one Securon SR 240mg tablet a day.
If you have not taken Securon SR 240mg before, your
doctor may prescribe a lower dose such as a Half
Securon SR 120mg tablet each day. The maximum
dose to treat high blood pressure is 480mg each day.
This is usually taken as one Securon 240mg tablet in
the morning and one in the evening, leaving a gap of
about 12 hours between each dose.
Angina (chest pain)
The usual starting dose for angina is one Securon SR
240mg tablet taken twice a day. You should take one
tablet in the morning and one in the evening, with a gap
of about 12 hours in between them. Your doctor may
prescribe a lower dose according to your symptoms.
Following a heart attack
The usual dose following a heart attack is 360mg each
day. This may be taken as one Securon SR 240mg
tablet in the morning and a Half Securon SR 120mg
tablet in the evening or as one Half Securon SR 120mg
tablet taken three times a day. The doctor will usually
wait at least a week after your heart attack before
prescribing these tablets.
Half Securon SR is NOT recommended for children
under 12 years of age.
If you take more tablets than prescribed (an
overdose) you should contact a doctor or go to the
nearest hospital casualty department IMMEDIATELY
taking your tablets with you.

If you forget to take your tablets take them as soon
as you remember, unless it is almost time for your next
dose. If it is, do not take the missed dose at all. Never
double up on a dose to make up for the one you have
If you stop taking your tablets your condition may get
worse. It is important that you keep taking these tablets
until your doctor tells you to stop. Do NOT stop just
because you feel better.
Other things to remember about Securon SR and
Half Securon SR
Securon SR 240mg Tablets may be broken in half if
your doctor advises you to do so (e.g. if a lower
dose has been prescribed).
The tablets should NOT be crushed or chewed, as
this will affect the modified-release formulation of the
4. Possible side effects
As with all medicines, Half Securon SR can cause side
effects, although not everyone will suffer from them. If
you experience any other unusual symptoms whilst
taking your tablets, tell your doctor or pharmacist.
Tell your doctor IMMEDIATELY if you experience
any of the following side effects:
Yellowing of the skin or eyes, a fever or tenderness
around the middle. These are signs that your liver
may not be functioning as well as usual
Palpitations, chest pains for the first time or chest
pains becoming more frequent, swollen ankles, hot
and painful hands or feet
Swelling of the limbs
Unexpected wheezing, difficulty breathing, swelling
of the mouth, lips or tongue or severe skin rash
The most common side effect is constipation. Other
side effects include abnormal heart beat, flushing of the
face or neck, headaches, feeling or being sick,
abdominal pain or discomfort, dizziness, vertigo,
tinnitus (ringing or buzzing in the ears), tiredness,
tremor, movement disorders, muscle weakness, aches
and pains in the joints and/or muscles, skin rash or
itching, a tingling or prickling feeling on the skin,
numbness and hair loss. Impotence may occur rarely.

Other side effects might occur if Half Securon SR is
used for a long time. Tell your doctor if you develop
swollen gums which start to spread over your teeth or if
your breasts swell (males) or start to produce milk
(males and females). These effects are rare and are
resolved upon stopping taking the tablets.
Reporting of side effects
If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible
side effects not listed in this leaflet. You can also
report side effects directly via the Yellow Card
Scheme at:
By reporting side effects, you can help provide more
information on the safety of this medicine.
5. How should you store your tablets?
Keep out of the sight and reach of children.
Do not store above 25°C.
Keep them in the original package.
If the tablets become discoloured or show any signs
of deterioration, seek the advice of your pharmacist.
Do not take the tablets after the expiry date which is
stated on the carton and blister label after ‘Exp’. The
expiry date refers to the last day of that month.
If your doctor tells you to stop taking this medicine,
return any unused tablets to your pharmacist for
safe disposal. Only keep this medicine if your doctor
tells you to.
Medicines should not be disposed of via wastewater
or household waste. Ask your pharmacist how to
dispose of medicines no longer required. These
measures will help to protect the environment.

6. Further Information
What Half Securon SR contains:
Each film-coated tablet contains 120mg of verapamil
hydrochloride in a modified release formulation.
Each film-coated tablet also contains the following
inactive ingredients: sodium alginate, povidone K30,
magnesium stearate, macrogol 400, macrogol 6000,
hydroxylpropyl methylcellulose, microcrystalline
cellulose, montan glycol wax, talc and titanium dioxide
What Half Securon SR looks like and contents of
the pack:
The tablets are white, round, biconvex and marked with
‘KNOLL’ on one side and ‘120 SR’ on the other side.
Half Securon SR is available as blister packs of 20 and
100 tablets.
Manufactured by: Abbott GmbH & Co. A.G.,
Knollstrasse 50, 67061 Ludwigshafen, Germany.
Procured from within the EU and repackaged by the
Product Licence holder: B&S Healthcare, Unit 4,
Bradfield Road, Ruislip, Middlesex, HA4 0NU, UK.

Half Securon SR Tablets
PL 18799/2758


Date: 14.09.2016
Securon is a registered trademark of Mylan Healthcare

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.