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Patient Information Leaflet: Information for the User

Half Securon® SR 120mg modified release tablets
(verapamil hydrochloride)
Read all of this leaflet carefully before you start taking this
 Keep this leaflet as you may need to read it again.
 This leaflet provides a summary of the information currently available
about Securon SR and Half Securon SR.
 For further information or advice ask your doctor or pharmacist.
 This medicine is for you only and should never be given to anyone
else, even if they appear to have the same symptoms as you.
 Tell your doctor or pharmacist if you experience any side effects.
 The name of this medicine is Half Securon® SR 120mg modified
release tablets but will be referred to as Half Securon SR throughout
the remainder of this leaflet.
 The strength Securon SR 240mg is also available.
Leaflet contents:
1) What is Securon SR / Half Securon SR and what is it used for?
2) What should you know before taking your tablets?
3) How should you take your tablets?
4) Possible side effects.
5) How should you store your tablets?
6) Further information.
Securon SR and Half Securon SR tablets belong to a group of medicines
called calcium channel blockers. Calcium channel blockers change the
amount of calcium getting into the muscle cells in your heart and blood
vessels. This can change the strength and speed with which your heart
beats. It also opens up the blood vessels so blood can be pumped
around the body more easily. This helps more oxygen to get to your heart
muscle and can lower your blood pressure.
Securon SR and Half Securon SR tablets are used to treat hypertension
(high blood pressure) and to prevent angina (chest pain) attacks. The
tablets may also be prescribed following a heart attack, to prevent
another attack occuring.
The active ingredient in Securon SR and Half Securon SR tablets is
verapamil hydrochloride.
If the answer to any of the following questions is ‘YES’ please tell
your doctor or pharmacist BEFORE taking any tablets:
 Are you sensitive (allergic) to verapamil or any of the ingredients in the
tablets? (See Section 6).
 Are you pregnant or planning to become pregnant, or are you breast
 Do you have very low blood pressure?
 Do you have or have you ever suffered from heart problems such as
heart failure?
 Do you have an abnormally slow or irregular heart beat?
 Have you recently had a heart attack?
 Do you have liver or kidney problems?
 Do you have or have you ever suffered from heart problems such as
heart failure or the heart condition called Wolff-Parkinson-White
 Do you have a condition where the nerve to muscle transmission is
affected e.g. myasthemia gravis, Lambert-Eaton syndrome, advanced
Duchenne muscular dystrophy?
 Are you being treated with ivabradine (for heart conditions)?

Taking other medicines
Please tell your doctor or pharmacist if you are taking any
medicines with or without a prescription or have recently taken any
of the following medicines:
 beta-blockers used to treat high blood pressure and heart conditions
(these include atenolol, propranolol and metoprolol)
 alpha blockers used to treat high blood pressure and heart conditions
(these include prazosin and terazosin)
 diuretics (also called “water pills”)
 medicines known as “statins” such as atorvastatin, lovastatin,
simvastatin used to lower cholesterol levels
 any other medicine for high blood pressure or an abnormal heart beat
(arrhythmia) such as quinidine, flecainide, digoxin and digitoxin
 dabigatran (medicine to prevent the formation of blood clots)
 medicines containing ivabradine for the treatment of certain heart
 medicines used to treat depression (including the herbal product
St John’s Wort), anxiety or psychosis. These may include imipramine,
buspirone and lithium.
 medicines known as immunosuppressants such as ciclosporin,
sirolimus, everolimus and tacrolimus. These are used to prevent organ
transplant rejection.
 glibenclamide, used to treat certain types of diabetes
 aspirin, a non-steroidal anti-inflammatory painkiller (NSAID) used to
relieve pain and reduce fever
 almotriptan, used to treat migraine
 midazolam, used as a sedative or anaesthetic
 theophylline, used to treat asthma
 doxorubicin, an anti-cancer medicine
 cimetidine, used to treat indigestion or stomach ulcers
 carbamazepine, phenytoin or phenobarbital (phenobarbitone). These
medicines are used as anti-convulsants.
 rifampicin, used to treat tuberculosis and other types of infection
 ritonavir, used to treat HIV
 erythromycin, clarithromycin and telithromycin, used to treat certain
types of infection
 colchicine or sulfinpyrazone, used to treat gout.
Tell your surgeon or dentist that you are taking Securon SR or Half
Securon SR if surgery is planned as it may affect the anaesthetic used.
Driving and operating machines
Do NOT drive, operate machinery or do anything that requires you to be
alert, until you know how the tablets affect you.
Securon SR and Half Securon SR can make some people feel dizzy,
especially when they first start to take the tablets.
Other important information
Do NOT drink grapefruit juice whilst taking your tablets as it can affect
the absorption of this medicine. This does not occur with other fruit juices
such as orange, apple or tomato juice.
Drinking alcohol
Securon SR and Half Securon SR will increase the time your body takes
to get rid of alcohol. This means that you may not have to drink as much
for your blood alcohol levels to be above the legal limit to drive. It will also
take you longer to sober up.
Taking Securon SR and Half Securon SR with food and drink
Your tablets can be taken with a glass of water to help you swallow them.
It does not matter if you have eaten, so they can be taken with or without
Pregnancy and breast feeding
Please discuss with your doctor if you are pregnant, planning to become
pregnant or are breast feeding.

ALWAYS take your tablets exactly as your doctor has told you. If you are
not sure refer to the label on the carton or check with your doctor or
TAKE YOUR TABLETS with a glass of water. You should swallow the
tablets without chewing or crushing them. It does not matter if you have
not eaten.
The number of tablets that you will need to take will depend on what you
are being treated for:
Hypertension (high blood pressure)
The usual dose is one Securon SR 240mg tablet a day. If you have not
taken Securon SR 240mg before, your doctor may prescribe a lower
dose such as a Half Securon SR 120mg tablet each day. The maximum
dose to treat high blood pressure is 480mg each day.
This is usually taken as one Securon SR 240mg tablet in the morning
and one in the evening, leaving a gap of about 12 hours between each
Angina (chest pain)
The usual starting dose for angina is one Securon SR 240mg tablet
taken twice a day. You should take one tablet in the morning and one in
the evening, with a gap of about 12 hours in between them. Your doctor
may prescribe a lower dose according to your symptoms.
Following a heart attack
The usual dose following a heart attack is 360mg each day. This may be
taken as one Securon SR 240mg tablet in the morning and a Half
Securon SR 120mg tablet in the evening or as one Half Securon SR
120mg tablet taken three times a day. The doctor will usually wait at least
a week after your heart attack before prescribing these tablets.
Securon SR and Half Securon SR are NOT recommended for children
under 12 years of age.
If you take more tablets than prescribed (an overdose) you should
contact a doctor or go to the nearest hospital casualty department
IMMEDIATELY taking your tablets with you.
If you forget to take your tablets take them as soon as you remember,
unless it is almost time for your next dose.
If it is, do not take the missed dose at all. Never double up on a dose to
make up for the one you have missed.
If you stop taking your tablets your condition may get worse. It is
important that you keep taking these tablets until your doctor tells you to
stop. Do NOT stop just because you feel better.
Other things to remember about Securon SR and Half Securon SR
 Securon SR 240mg tablets may be broken in half if your doctor
advises you to do so (e.g. if a lower dose has been prescribed).
 The tablets should NOT be crushed or chewed, as this will affect the
modified-release formulation of the product.
As with all medicines, Securon SR and Half Securon SR can cause side
effects, although not everyone will suffer from them. If you experience
any other unusual symptoms whilst taking your tablets, tell your
doctor or pharmacist.
Tell your doctor IMMEDIATELY if you experience any of the
following side effects:
 Yellowing of the skin or eyes, a fever or tenderness around the middle.
These are signs that your liver may not be functioning as well as usual
 Palpitations, chest pains for the first time or chest pains becoming
more frequent, swollen ankles, hot and painful hands or feet
 Swelling of the limbs
 Unexpected wheezing, difficulty breathing, swelling of the mouth, lips
or tongue or severe skin rash
The most common side effect is constipation. Other side effects include
abnormal heart beat, flushing of the face or neck, headaches, feeling or
being sick, abdominal pain or discomfort, dizziness, vertigo, tinnitus
(ringing or buzzing in the ears), tiredness, tremor, movement disorders,
muscle weakness, aches and pains in the joints and/or muscles, skin
rash or itching, a tingling or prickling feeling on the skin, numbness and
hair loss. Impotence may occur rarely.

Other side effects might occur if Securon SR or Half Securon SR are
used for a long time. Tell your doctor if you develop swollen gums
which start to spread over your teeth, or if your breasts swell (males) or
start to produce milk (males and females). These effects are rare and are
resolved upon stopping taking the tablets.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This
includes any possible side effects not listed in this leaflet. You can also
report side effects directly via the Yellow Card Scheme at:
By reporting side effects, you can help provide more information on the
safety of this medicine.

Keep out of the sight and reach of children.
Do not store above 25oC.
Store in the original package.
Do not use this medicine after the expiry date which is stated on the
carton label and blister foil after EXP. The expiry date refers to the last
day of that month.
 If your tablets become discoloured or show any sign of deterioration,
return them to your pharmacist.
 Medicines should not be disposed of via wastewater or household
waste. Ask your pharmacist how to dispose of medicines no longer
required. These measures will help to protect the environment.
What Half Securon SR tablets contain:
Each tablet contains 120mg verapamil hydrochloride.
The other ingredients are:
microcrystalline cellulose, sodium alginate, povidone, magnesium
stearate, hypromellose, macrogol 400, macrogol 6000, talc, titanium
dioxide (E171) and montan wax.
What Half Securon SR tablets look like and contents of the pack:
Half Securon SR tablets are round, white, biconvex and embossed with
the word 'Knoll' on one side and '120 SR' on the reverse.
The tablets are available in packs of 30, 40 and 60 tablets.
Manufactured by
AbbVie Deutschland GmbH & Co.KG., Knollstrasse 50, D-67061
Ludwigshafen, Germany
Famar Anthoussa, Greece.
Procured from within the EU by Product Licence holder:
MPT Pharma Ltd, Westgate Business Park, Unit 5-7 Tintagel Way,
Aldridge, Walsall, WS9 8ER. UK
Repackaged by MPT Pharma Ltd.
PL: 33532/0457
Leaflet dated 29th September 2016
Leaflet coded XXXXXXXXXX


Securon® is a registered trademark of xxxxxxxxxxxxxxxxxxxxxxxxxxxx.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.