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GOLDEN EYE ANTIBIOTIC 0.5% W/V EYE DROPS

Active substance(s): CHLORAMPHENICOL

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Chloramphenicol Eye Drops BP 0.5% w/v

What is in this leaflet
1. What Chloramphenicol Eye Drops are and what
they are used for
2. What you need to know before you use
Chloramphenicol Eye Drops
3. How to use Chloramphenicol Eye Drops
4. Possible side effects
5. How to store Chloramphenicol Eye Drops
6. Contents of the pack and other information
1. WHAT CHLORAMPHENICOL EYE DROPS
ARE AND WHAT ARE THEY USED FOR
Chloramphenicol Eye Drops contain an antibiotic
called chloramphenicol. It is used to treat
bacterial infections that affect the front surfaces
of the eye.
The most common type of infection in this area is
called acute bacterial conjunctivitis. When you
have acute bacterial conjunctivitis the white part
of one or both of your eyes will be red and /or your
eyelids will be red or swollen. There will be a sticky
discharge, which can make the eye difficult to
open in the morning and the eye may feel ‘gritty’
or ‘irritated’.
Chloramphenicol Eye Drops are not suitable for
treating eye infections that have spread to the
deeper layers of the eye coverings or into the fluid
within the eyeball. Antibiotic tablets or injections
are needed to treat these deeper, more serious
infections.
2. WHAT YOU NEED TO KNOW BEFORE YOU
USE CHLORAMPHENICOL EYE DROPS
Chloramphenicol Eye Drops are recommended for
use in children aged 2 years and over, in adults
and the elderly. A child below the age of 2 years
with an eye infection should be seen by a doctor.
Do not use this product if you:
• are allergic to Chloramphenicol or any of the
ingredients of this medicine (listed in section 6).
• have ever had problems with your blood
(in particular very low number of blood cells)
during previous treatment with chloramphenicol
• have a family history of blood problems such as
low white blood cell, red blood cell, or platelet
counts

Do not use this product and seek advice
from your doctor if:
• your eyesight is affected (loss of sight, reduced
vision, blurred vision or halos around lights)
• you have pain within the eye
• your eye has suffered a blow or other injury
• your eye is inflamed and you have a rash on the
scalp or face
• the pupil of your eye looks unusual or your eye
looks cloudy
• your eyes are sensitive to light
• you have (or think you have) a foreign body in
your eye, which has not been removed
• you have recently had an eye infection
• you suffer from or have suffered from glaucoma
or dry eye syndrome
• you wear contact lenses. If you wear contact
lenses and your contact lens practitioner or
doctor has advised you to use this product,
do not wear your lenses during the course of
treatment. Wear your glasses instead. Soft
contact lenses should not be used for 24 hours
after completing treatment.
• you are using any other eye drops or eye
ointment
• you have had eye surgery or laser treatment in
the last 6 months

Tell your pharmacist before using this
product if you:
• are taking any other medicines.
• suffer from any other eye problems.

Other medicines and Chloramphenicol
Eye Drops
If you are taking bone marrow depressant
medicines (medicines which decrease the activity
of the bone marrow, causing low blood cell
counts) such as azathioprine or are receiving
chemotherapy, seek the advice of your pharmacist
or your doctor before using this product.

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you
may be pregnant or are planning to have a baby,
ask your doctor or pharmacist for advice before
using this medicine.

Driving and using machines

After using the drops, you may temporarily get
blurred vision. Do not drive or operate machinery
until your vision is clear. If in doubt, talk to your
pharmacist or doctor.

Chloramphenicol Eye Drops contains
phenylmercuric nitrate

Phenylmercuric nitrate may cause allergic
reactions.
3. HOW TO USE CHLORAMPHENICOL EYE DROPS

Instructions for use

To be used in the eye(s) only
• Check that the seal is not broken before the
first use.
• Wash and dry your hands

V1-150729

Read all of this leaflet carefully before you
start using this medicine because it contains
important information for you.
Always use this medicine exactly as described
in this leaflet or as your doctor or pharmacist
told you.
• Keep this leaflet. You may need to read it
again.
• Ask your pharmacist if you need more
information or advice.
• If you get any side effects, talk to your
doctor or pharmacist. This includes any
possible side effects not listed in this leaflet.
• You must talk to a doctor if you do not feel
better or if you feel worse after 48 hours.

For external use only.
Dose

Apply one drop to the affected eye(s) every
2 hours for the first two days and every
4 hours thereafter. Use during waking hours only.

Length of treatment

The course of treatment is 5 days. Keep using
these eye drops for 5 days. Do not stop just
because you feel better, this could make your
condition worse.
If your symptoms do not improve within
48 hours, consult your doctor. If your symptoms
get worse seek medical advice at once.
Do not use Chloramphenicol Eye Drops for more
than 5 days without consulting doctor. Dispose of
any remaining eye drops appropriately after the 5
day course of treatment (see section 5).

If you forget to use your drops

If you have only just missed a dose and it is a long
time before the next dose is due, put in the missed
dose of drops straight away. If it is nearly time for
your next dose, skip the missed dose and just put in
the next dose of drops at the usual time. Do not
take a double dose to make up for a forgotten dose.
4. POSSIBLE SIDE EFFECTS
Like all medicines, this medicine can cause side
effects, although not everybody gets them. Some
people may get one or more of these side effects.
Some effects happen straight away but do not last
long - others may only happen after several days of
use.
• Allergic reactions such as itching or rashes.
If you get a severe reaction, with swelling or
breathing problems get medical help straight
away.
• Changes in the blood (anaemia) leading to severe
tiredness or easy bruising. If you experience these
effects, stop using the drops immediately and tell
your doctor.
• Discolouration or clouding of the eye surface
(cornea) or lens due to preservative.
• The use of topical Chloramphenicol may
occasionally result in the over growth of other non
susceptible organisms including fungi. If any new
infection appears during treatment you should tell
your doctor.

• Blurred vision or mild burning or stinging when
you put the drops in. These should subside quickly.
• Irritation of the skin around the eyes,
mercurialentis (brown discolouration of the lens)
and atypical band keratopathy (appearance of
calcium on the cornea). These may be due to the
preservative in the drops called phenylmercuric
nitrate.
If you do not feel well or are worried about your
health, talk to a pharmacist or doctor.
If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects
not listed in this leaflet.
Reporting side effects
If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report
side effects directly via the Yellow Card Scheme at
www.mhra.gov.uk/yellowcard
By reporting side effects you can help provide more
information on the safety of this medicine.
5. HOW TO STORE CHLORAMPHENICOL
EYE DROPS
Replace the cap securely after use. Store at 2°C
to 8°C. This is the temperature of most domestic
refrigerators.
Keep this and all medicines out of the sight and
reach of children.
Do not use after the expiry date which is stated on
the bottle and on the carton the bottle is packed in.
Dispose of any medicine left at the end of a 5 day
course of treatment.
Do not throw away any medicines via waste water
or household waste. Ask your pharmacist how to
throw away medicines you no longer use. These
measures will help protect the environment.
6. CONTENTS OF THE PACK AND
OTHER INFORMATION
What Chloramphenicol Eye Drops contains
- The active substance is Chloramphenicol
0.5% w/v.
- The other ingredients are: borax, boric acid, phenyl
mercuric nitrate (as preservative)
0.002% w/v and water for injections.

What Chloramphenicol Eye Drops looks like
and contents of the pack
Each bottle contains 10 ml of drops.
The drops contain 0.5% w/v chloramphenicol,
which is equivalent to 5 mg of chloramphenicol
per millilitre. Chloramphenicol Eye Drops is a clear,
colourless, sterile solution.

Marketing Authorisation Holder
Medicom Healthcare Ltd
235 Hunts Pond Road, Titchfield Common
Fareham, Hants
PO14 4PJ UK

Manufacturer

Excelvision, 27,
rue de la Lombardière, BP 131,
07100 Annonay, France

Distributed by

AAH Pharmaceuticals Ltd,
Coventry, CV2 2TX

PL number: 18956/0004
Hard to see or read the leaflet?
Call +44 (0) 1489 574119 for help
This leaflet was last revised in 11/2015

COLDP-42-GB-PV1

V4-160105

• Tilt your head back while seated or lie down on
your back
• Gently pull the lower eyelid downwards and look
up
• Place the tip of the bottle close to your eye.
Squeeze the bottle and let one drop fall into the
space between the lower eyelid and the eye. Take
care that the tip of the bottle does not touch your
eye, the skin around your eye or your fingers.
• Close your eye for a moment.
• When both eyes are to be treated, repeat for the
other eye
• Replace and tighten the cap immediately after use.
Whilst applying the drops, do not
• breathe on or touch the dropper nozzle
• touch the eyes or eyelids (or any other surface)
with the tip of the bottle
• share your eye drops with anyone else.

Chloramphenicol Eye Drops BP 0.5% w/v

What is in this leaflet
1. What Chloramphenicol Eye Drops are and what
they are used for
2. What you need to know before you use
Chloramphenicol Eye Drops
3. How to use Chloramphenicol Eye Drops
4. Possible side effects
5. How to store Chloramphenicol Eye Drops
6. Contents of the pack and other information
1. WHAT CHLORAMPHENICOL EYE DROPS
ARE AND WHAT ARE THEY USED FOR
Chloramphenicol Eye Drops contain an antibiotic
called chloramphenicol. It is used to treat
bacterial infections that affect the front surfaces
of the eye.
The most common type of infection in this area is
called acute bacterial conjunctivitis. When you
have acute bacterial conjunctivitis the white part
of one or both of your eyes will be red and /or your
eyelids will be red or swollen. There will be a sticky
discharge, which can make the eye difficult to
open in the morning and the eye may feel ‘gritty’
or ‘irritated’.
Chloramphenicol Eye Drops are not suitable for
treating eye infections that have spread to the
deeper layers of the eye coverings or into the fluid
within the eyeball. Antibiotic tablets or injections
are needed to treat these deeper, more serious
infections.
2. WHAT YOU NEED TO KNOW BEFORE YOU
USE CHLORAMPHENICOL EYE DROPS
Chloramphenicol Eye Drops are recommended for
use in children aged 2 years and over, in adults
and the elderly. A child below the age of 2 years
with an eye infection should be seen by a doctor.
Do not use this product if you:
• are allergic to Chloramphenicol or any of the
ingredients of this medicine (listed in section 6).
• have ever had problems with your blood
(in particular very low number of blood cells)
during previous treatment with chloramphenicol
• have a family history of blood problems such as
low white blood cell, red blood cell, or platelet
counts

Do not use this product and seek advice
from your doctor if:
• your eyesight is affected (loss of sight, reduced
vision, blurred vision or halos around lights)
• you have pain within the eye
• your eye has suffered a blow or other injury
• your eye is inflamed and you have a rash on the
scalp or face
• the pupil of your eye looks unusual or your eye
looks cloudy
• your eyes are sensitive to light
• you have (or think you have) a foreign body in
your eye, which has not been removed
• you have recently had an eye infection
• you suffer from or have suffered from glaucoma
or dry eye syndrome
• you wear contact lenses. If you wear contact
lenses and your contact lens practitioner or
doctor has advised you to use this product,
do not wear your lenses during the course of
treatment. Wear your glasses instead. Soft
contact lenses should not be used for 24 hours
after completing treatment.
• you are using any other eye drops or eye
ointment
• you have had eye surgery or laser treatment in
the last 6 months

Tell your pharmacist before using this
product if you:
• are taking any other medicines.
• suffer from any other eye problems.

Other medicines and Chloramphenicol
Eye Drops
If you are taking bone marrow depressant
medicines (medicines which decrease the activity
of the bone marrow, causing low blood cell
counts) such as azathioprine or are receiving
chemotherapy, seek the advice of your pharmacist
or your doctor before using this product.

Pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you
may be pregnant or are planning to have a baby,
ask your doctor or pharmacist for advice before
using this medicine.

Driving and using machines

After using the drops, you may temporarily get
blurred vision. Do not drive or operate machinery
until your vision is clear. If in doubt, talk to your
pharmacist or doctor.

Chloramphenicol Eye Drops contains
phenylmercuric nitrate

Phenylmercuric nitrate may cause allergic
reactions.
3. HOW TO USE CHLORAMPHENICOL EYE DROPS

Instructions for use

To be used in the eye(s) only
• Check that the seal is not broken before the
first use.
• Wash and dry your hands

V1-150728

Read all of this leaflet carefully before you
start using this medicine because it contains
important information for you.
Always use this medicine exactly as described
in this leaflet or as your doctor or pharmacist
told you.
• Keep this leaflet. You may need to read it
again.
• Ask your pharmacist if you need more
information or advice.
• If you get any side effects, talk to your
doctor or pharmacist. This includes any
possible side effects not listed in this leaflet.
• You must talk to a doctor if you do not feel
better or if you feel worse after 48 hours.

For external use only.
Dose

Apply one drop to the affected eye(s) every
2 hours for the first two days and every
4 hours thereafter. Use during waking hours only.

Length of treatment

The course of treatment is 5 days. Keep using
these eye drops for 5 days. Do not stop just
because you feel better, this could make your
condition worse.
If your symptoms do not improve within
48 hours, consult your doctor. If your symptoms
get worse seek medical advice at once.
Do not use Chloramphenicol Eye Drops for more
than 5 days without consulting doctor. Dispose of
any remaining eye drops appropriately after the 5
day course of treatment (see section 5).

If you forget to use your drops

If you have only just missed a dose and it is a long
time before the next dose is due, put in the missed
dose of drops straight away. If it is nearly time for
your next dose, skip the missed dose and just put in
the next dose of drops at the usual time. Do not
take a double dose to make up for a forgotten dose.
4. POSSIBLE SIDE EFFECTS
Like all medicines, this medicine can cause side
effects, although not everybody gets them. Some
people may get one or more of these side effects.
Some effects happen straight away but do not last
long - others may only happen after several days of
use.
• Allergic reactions such as itching or rashes.
If you get a severe reaction, with swelling or
breathing problems get medical help straight
away.
• Changes in the blood (anaemia) leading to severe
tiredness or easy bruising. If you experience these
effects, stop using the drops immediately and tell
your doctor.
• Discolouration or clouding of the eye surface
(cornea) or lens due to preservative.
• The use of topical Chloramphenicol may
occasionally result in the over growth of other non
susceptible organisms including fungi. If any new
infection appears during treatment you should tell
your doctor.

• Blurred vision or mild burning or stinging when you
put the drops in. These should subside quickly.
• Irritation of the skin around the eyes,
mercurialentis (brown discolouration of the lens)
and atypical band keratopathy (appearance of
calcium on the cornea). These may be due to the
preservative in the drops called phenylmercuric
nitrate.
If you do not feel well or are worried about your
health, talk to a pharmacist or doctor.
If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects
not listed in this leaflet.
Reporting side effects
If you get any side effects, talk to your doctor,
pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report
side effects directly via the Yellow Card Scheme at
www.mhra.gov.uk/yellowcard
By reporting side effects you can help provide more
information on the safety of this medicine.
5. HOW TO STORE CHLORAMPHENICOL
EYE DROPS
Replace the cap securely after use. Store at 2°C
to 8°C. This is the temperature of most domestic
refrigerators.
Keep this and all medicines out of the sight and
reach of children.
Do not use after the expiry date which is stated on
the bottle and on the carton the bottle is packed in.
Dispose of any medicine left at the end of a 5 day
course of treatment.
Do not throw away any medicines via waste water
or household waste. Ask your pharmacist how to
throw away medicines you no longer use. These
measures will help protect the environment.
6. CONTENTS OF THE PACK AND
OTHER INFORMATION
What Chloramphenicol Eye Drops contains
- The active substance is Chloramphenicol
0.5% w/v.
- The other ingredients are: borax, boric acid, phenyl
mercuric nitrate (as preservative)
0.002% w/v and water for injections.

What Chloramphenicol Eye Drops looks like
and contents of the pack
Each bottle contains 10 ml of drops.
The drops contain 0.5% w/v chloramphenicol,
which is equivalent to 5 mg of chloramphenicol
per millilitre. Chloramphenicol Eye Drops is a clear,
colourless, sterile solution.

Marketing Authorisation Holder
Medicom Healthcare Ltd
235 Hunts Pond Road, Titchfield Common
Fareham, Hants
PO14 4PJ UK

Manufacturer

Excelvision, 27,
rue de la Lombardière, BP 131,
07100 Annonay, France

Distributed by

AAH Pharmaceuticals Ltd,
Coventry, CV2 2TX

PL number: 18956/0004
Hard to see or read the leaflet?
Call +44 (0) 1489 574119 for help
This leaflet was last revised in 11/2015

COLDP-43-GB-PV1

V4-160105

• Tilt your head back while seated or lie down on
your back
• Gently pull the lower eyelid downwards and look
up
• Place the tip of the bottle close to your eye.
Squeeze the bottle and let one drop fall into the
space between the lower eyelid and the eye. Take
care that the tip of the bottle does not touch your
eye, the skin around your eye or your fingers.
• Close your eye for a moment.
• When both eyes are to be treated, repeat for the
other eye
• Replace and tighten the cap immediately after use.
Whilst applying the drops, do not
• breathe on or touch the dropper nozzle
• touch the eyes or eyelids (or any other surface)
with the tip of the bottle
• share your eye drops with anyone else.

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

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