GLYCERINE LEMON AND HONEY LINCTUSView full screen / Print PDF » Download PDF ⇩
NAME OF THE MEDICINAL PRODUCT
Glycerin Lemon and Honey Expectorant
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each 5ml contains:
Squill Elixir BP 0.5ml
Ipecacuanha Liquid Extract BP 0.02ml
Citric Acid Mononydrate BP 0.025mg
Tolu Syrup BP 0.5ml
For soothing sore throats or tickly coughs.
Posology and method of administration
Dose (Taken Orally): To be sipped and swallowed slowly 3 or 4 times a day
Not recommended for children under 6 years old.
For children 6 to 12 years old:
One 5ml spoonful three or four times a day (sipped and swallowed slowly)
Two 5ml spoonful three or four times a day (sipped and swallowed slowly)
Impaired renal function, impaired hepatic function, cardiac disorders,
moderate to severe respiratory insufficiency, alcoholism and raised intracranial
Hypersensitivity to any of the actives/excipients.
Not recommended for children under 3 years.
Special warnings and precautions for use
The product contains ipecac and squill both of which are cardioactive and
hence should not be used in patients receiving anti-arrhythmic therapy. This
product cotains sugar.Dental hygiene after each dose is recommended and it is
best avoided by diabetic patients. The stated dose should not be exceeded and
if symptoms persist or deteriorate after 5 days of treatment, a doctor should be
Interaction with other medicinal products and other forms of interaction
Theoretical risk of interaction with anti-arrhythmic drugs through this is
unlikely at recommended doses.
Fertility, pregnancy and lactation
Avoid use during pregnancy.
Squill: There is a documented abortifacient effect. It also modulates the
Effects on ability to drive and use machines
Gastric irritation, nausea and vomiting. Occasionally moderate to severe
diarrhoea can occur if hypersensitive to squill.
Symptoms of overdose are similar to other undesirable effects stated above but
more exaggerated. When taken in large doses, blood diarrhoea, musocal
erosion and albuminuria can occur. If symptoms and signs due to squill
dominate, the clinical picture resembles dioxin toxicity. Fluid and electrolyte
balance together with ECG should be monitored and other symptomatic and
supportive measures should be provided.
Pharmacotherapeutic group: Cold and Cough expectorant
ATC code: R0SCA04
At the levels which they are present in this product the Squill Elixir and the
Ipecacuanha Liquid Extract act as expectorants due to their irritant effect on the
The Citric Acid is present for its cooling properties. It has been used as a cooling
drink to relieve thirst if fever.
Tolu Syrup has mild antiseptic properties and some expectorant action however it is
normally considered as flavour.
The alkaloids from the Ipecacuanha and the glyco sides from the quill are
absorbed by the gastric mucosa, metabolised and excreted in the urine and
faeces. Emetine being the slowest of the ingredients to be metabolised.
Citric Acid is absorbed and oxidised in the body to Carbondioxide and water.
The balsamic acids of the Tolu are absorbed, metabolised and excreted in the
urine and faeces.
Preclinical safety data
List of excipients
Compound Tartrazine Solution
Special precautions for storage
Nature and contents of container
Glass bottles (100ml), (200ml).
Special precautions for disposal
MARKETING AUTHORISATION HOLDER
Activase Pharmaceuticals Limited,
11 Boumpoulinas, 3rd Floor,
MARKETING AUTHORISATION NUMBER(S)
DATE OF FIRST AUTHORISATION/RENEWAL OF THE
DATE OF REVISION OF THE TEXT
Source: Medicines and Healthcare Products Regulatory Agency
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