Skip to Content

UK Edition. Click here for US version.

FLUCONAZOLE 150MG HARD CAPSULES

Active substance(s): FLUCONAZOLE

View full screen / Print PDF » Download PDF ⇩
Transcript
PATIENT INFORMATION LEAFLET
Fluconazole 150mg Hard Capsules
Please read this carefully before you start taking
this medicine.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or
pharmacist.
• This medicine has been prescribed for you. Do not
pass it on to others. It may harm them, even if their
symptoms are the same as yours.
• If any of the side effects gets serious, or if you notice
any side effects not listed in this leaflet, please tell
your doctor or pharmacist.
In this leaflet:
1. What Fluconazole 150 mg Capsules are and what
they are used for
2. What You Need To Know Before You Take Fluconazole
150 Mg Capsules
3. How to take Fluconazole 150 mg Capsules
4. Possible side effects
5. How to store Fluconazole 150 mg Capsules
6. Contents of the pack and other information
1.WHAT FLUCONAZOLE 150 MG CAPSULES ARE
AND WHAT THEY ARE USED FOR
The active substance is fluconazole. Fluconazole is one
of a group of medicines called “antifungals”.
Fluconazole is used to treat infections caused by
fungi and may also be used to stop you from getting a
candidal infection. The most common cause of fungal
infections is a yeast called Candida.
You might be given this medicine by your doctor to treat
genital thrush, infection of the vagina or penis.
2. WHAT YOU NEED TO KNOW BEFORE YOU TAKE
FLUCONAZOLE 150 MG CAPSULES
Do not take Fluconazole 150 mg Capsules if you
• are allergic (hypersensitive) to fluconazole, to other
medicines you have taken to treat fungal infections or
to any of the other ingredients of Fluconazole
150 mg Capsules. The symptoms may include itching,
reddening of the skin or difficulty in breathing
• are taking astemizole, terfenadine (antihistamine
medicines for allergies)
• are taking cisapride (used for stomach upsets)
• are taking pimozide (used for treating mental illness)
• are taking quinidine (used for treating heart
arrhythmia)
• are taking erythromycin (an antibiotic for treating
infections)
• if you are taking amiodarone (used for treating
uneven heartbeats ‘arrhythmias’)
Warnings and precautions
Talk to your doctor or pharmacist before taking
Fluconazole 150mg Capsules if you
• have liver or kidney problems
• suffer from heart disease, including heart rhythm
problems
• have abnormal levels of potassium, calcium or
magnesium in your blood
• develop severe skin reactions (itching, reddening of
the skin or difficulty in breathing).
• develop signs of ‘adrenal insufficiency’ where the
adrenal glands do not produce adequate amounts of
certain steroid hormones such as cortisol (chronic,
or long lasting fatigue, muscle weakness, loss of
appetite, weight loss, abdominal pain)
Children
Although this medicine is for adults it can be used in
adolescents (from 12 to 17 years old) if treatment is
essential and no suitable alternative exists, and should
be taken in the same way as for adults.
Other medicines and Fluconazole 150mg Capsules
Tell your doctor immediately if you are taking astemizole,
terfenadine (an antihistamine for treating allergies) or
cisapride (used for stomach upsets) or pimozide (used
for treating mental illness) or quinidine (used for treating
heart arrhythmia) or erythromycin (an antibiotic for
treating infections) as these should not be taken with
Fluconazole 150 mg Capsules (see section: “Do not take
Fluconazole 150 mg Capsules if you”).
There are some medicines that may interact with
Fluconazole 150 mg Capsules. Make sure your doctor
knows if you are taking any of the following medicines:
• rifampicin or rifabutin (antibiotics for infections)
• alfentanil, fentanyl (used as anaesthetic)

• amitriptyline, nortriptyline (used as anti-depressant)
• amphotericin B, voriconazole (anti-fungal)
• medicines that thin the blood to prevent blood clots
(warfarin or similar medicines)
• benzodiazepines (midazolam, triazolam or similar
medicines) used to help you sleep or for anxiety
• carbamazepine, phenytoin (used for treating fits)
• nifedipine, isradipine, amlodipine, felodipine and
losartan (for hypertension- high blood pressure)
• ciclosporin, everolimus , sirolimus or tacrolimus
(to prevent transplant rejection)
• cyclosphosphamide, vinca alkaloids (vincristine,
vinblastine or similar medicines) used for treating
cancer
• halofantrine (used for treating malaria)
• statins (atorvastatin, simvastatin and fluvastatin or
similar medicines) used for reducing high cholesterol
levels
• methadone (used for pain)
• celecoxib, flurbiprofen, naproxen, ibuprofen,
lornoxicam, meloxicam, diclofenac (Non-Steroidal
Anti-Inflammatory Drugs (NSAID))
• oral contraceptives
• prednisone (steroid)
• zidovudine, also known as AZT; saquinavir (used in
HIV-infected patients)
• medicines for diabetes such as chlorpropamide,
glibenclamide, glipizide or tolbutamide
• theophylline (used to control asthma)
• vitamin A (nutritional supplement)
• amiodarone (used for treating uneven heartbeats
‘arrhythmias’)
Tell your doctor or pharmacist if you are taking or have
recently taken any other medicines, including medicines
obtained without a prescription.
Taking Fluconazole 150 mg Capsules with food and
drink
You can take your medicine with or without a meal.
Pregnancy and breast-feeding
Tell your doctor if you are pregnant, trying to become
pregnant or breast-feeding. You should not take
Fluconazole 150 mg Capsules while you are pregnant or
breast-feeding unless your doctor has told you to.
Ask your doctor or pharmacist for advice before taking
any medicines.
You can continue breast-feeding after taking a single
dose of Fluconazole 150 mg Capsules.
You should not breast-feed if you are taking a repeated
dose of Fluconazole 150mg Capsules.
Driving and using machines
When driving vehicles or using machines, it should be
taken into account that occasionally dizziness or fits may
occur.
Important information about some of the ingredients
of Fluconazole 150 mg Capsules
This medicine contains a small amount of lactose
(milk sugar). If you have been told by your doctor that
you have an intolerance to some sugars, please contact
your doctor before taking this medicine.
The capsule also contains sunset yellow (E110), which
may cause allergic reactions, including asthma, in some
people. This is more common in people who are allergic
to aspirin.
3. HOW TO TAKE FLUCONAZOLE 150 MG
CAPSULES
Always take your medicine exactly as your doctor
has told you. You should check with your doctor or
pharmacist if you are not sure. Swallow the capsule
whole with a glass of water.
Adults
150mg as a single dose.
Doctors sometimes prescribe different doses to these.
Always take your medicine exactly as your doctor
has told you. You should check with your doctor or
pharmacist if you are not sure.
Elderly
The usual adult dose should be given.
Patients with kidney problems
The usual adult dose should be given.
How quickly will the treatment start to work?
Vaginal thrush
Your condition should start to clear up within a few days some women notice an improvement in one day. If your
condition does not clear up within a few days you should
go back to your doctor.

Penis thrush infection
Your condition should start to clear up within a few days
but it may take up to a week.
If your condition has not cleared up after one week, you
should go back to your doctor
If you take more Fluconazole 150 mg Capsules than
you should
Taking too many capsules at once may make you
unwell. Contact your doctor or your nearest hospital
casualty department at once. The symptoms of a
possible overdose may include hearing, seeing, feeling
and thinking things that are not real (hallucination and
paranoid behaviour). Symptomatic treatment (with
supportive measures and gastric lavage if necessary)
may be adequate.
If you forget to take Fluconazole 150 mg Capsules
Do not take a double dose to make up for a forgotten
dose. If you forget to take a dose, take it as soon as you
remember. If it is almost time for your next dose, do not
take the dose that you missed.
If you have any further questions on the use of this
medicine, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Fluconazole 150 mg Capsules can
cause side effects, although not everybody gets them
A few people develop allergic reactions although
serious allergic reactions are rare. If you get any of the
following symptoms, tell your doctor immediately.
• sudden wheezing, difficulty in breathing or tightness
in the chest
• swelling of eyelids, face or lips
• itching all over the body reddening of the skin or itchy
red spots
• skin rash
• severe skin reactions such as a rash that causes
blistering (this can affect the mouth and tongue).
Fluconazole 150 mg Capsules may affect your liver.
The signs of liver problems include:
• tiredness
• loss of appetite
• vomiting
• yellowing of your skin or the whites of your eyes
(jaundice)
Fluconazole Capsules may affect your adrenal glands
and the levels of steroid hormones produced. The signs
of adrenal problems include:
• tiredness
• muscle weakness
• loss of appetite
• weight loss
• abdominal pain
If any of these happen, stop taking Fluconazole 150 mg
Capsules and tell your doctor immediately.
Other side effects:
Additionally, if any of the following side effects gets
serious, or if you notice any side effects not listed in this
leaflet, please tell your doctor or pharmacist.
Common side effects which affect 1 to 10 users in 100
are listed below:
• headache
• stomach discomfort, diarrhoea, feeling sick, vomiting
• increases in blood tests of liver function
• rash
Uncommon side effects which affect 1 to 10 users in
1,000 are listed below:
• reduction in red blood cells which can make skin pale
and cause weakness or breathlessness
• decreased appetite
• inability to sleep, feeling drowsy
• fit, dizziness, sensation of spinning, tingling, pricking
or numbness, changes in sense of taste
• constipation, difficult digestion, wind, dry mouth
• muscle pain
• liver damage and yellowing of the skin and eyes
(jaundice)
• wheals, blistering (hives), itching, increased sweating
• tiredness, general feeling of being unwell, fever

Rare side effects which affect 1 to 10 users in 10,000
are listed below:
• lower than normal white blood cells that help defend
against infections and blood cells that help to stop
bleeding
• red or purple discoloration of the skin which may
be caused by low platelet count, other blood cell
changes
• blood chemistry changes (high blood levels of
cholesterol, fats)
• low blood potassium
• shaking
• abnormal electrocardiogram (ECG), change in heart
rate or rhythm
• liver failure
• allergic reactions (sometimes severe), including
widespread blistering rash and skin peeling, severe
skin reactions, swelling of the lips or face
• hair loss
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist
or nurse. This includes any possible side effects not listed
in this leaflet. You can also report side effects directly via
the yellow card scheme at www.mhra.gov.uk/yellowcard.
By reporting side effects you can help provide more
information on the safety of this medicine.
5. HOW TO STORE FLUCONAZOLE 150 MG
CAPSULES
Keep this medicine out of the sight and reach of children.
Do not use Fluconazole 150 mg Capsules after the
expiry date which is stated on the pack after EXP.
The expiry date refers to the last day of the month.
Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose
of medicines no longer required. These measures will
help to protect the environment.
6. FURTHER INFORMATION
What Fluconazole 150 mg Capsules contains
• The active substance is fluconazole.
• Each hard capsule contains 150 mg mg of
fluconazole.
• The other ingredients are:
Capsule content: lactose monohydrate, microcrystalline
cellulose, pregelatinised maize starch,
colloidal anhydrous silica, magnesium stearate and
sodium lauryl sulphate.
Capsule shell composition: titanium dioxide (E171),
quinoline yellow (E104), sunset yellow (E110) and
gelatin.
What Fluconazole 150 mg Capsules look like and
contents of the pack
Fluconazole 150 mg Capsules are yellow capsules.
Fluconazole 150 mg Capsules are available in a blister
pack containing 1 capsule.
Other formats:
To listen to or request a copy of this leaflet in Braille,
large print or audio please call, free of charge:
0800 198 5000 (UK Only)
Please be ready to give the following information:
Product name
Reference number
Fluconazole 150mg Hard PL 29831/0318
Capsules
This is a service provided by the Royal National Institute
of Blind People.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder
Wockhardt UK Ltd, Ash Road North, Wrexham,
LL13 9UF, UK.
Manufacturer
CP Pharmaceuticals Ltd, Ash Road North, Wrexham,
LL13 9UF, UK.
This leaflet was last revised in 12/2015

104531/6

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.

Hide