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Erythrocin® 250mg Tablets
(erythromycin stearate)
Read all of this leaflet carefully before you start taking this

Please keep this leaflet. You may need to read it again.

If you have any further questions, ask your doctor or

This medicine has been prescribed for you. Do not pass it
on to others. It may harm them, even if their symptoms are
the same as yours.

If any of the side effects become severe, or if you notice any
side effects not listed in this leaflet, please tell your doctor or
The name of your medicine is Erythrocin 250mg Tablets but will
be referred to as Erythrocin Tablets or Erythrocin throughout the
remainder of the leaflet.
Erythrocin Tablets are also available in another strength
In this leaflet:
1. What Erythrocin Tablets are and what they are used for
2. Before you take Erythrocin Tablets
3. How to take Erythrocin Tablets
4. Possible side effects
5. How to store Erythrocin Tablets
6. Further information.
1. What Erythrocin Tablets are and what they are used for
The name of your medicine is Erythrocin Tablets. Erythrocin
contains the active ingredient erythromycin which belongs to a
group of medicines called macrolide antibiotics.
Erythrocin Tablets are used to prevent and treat infections such

Throat and sinus infections.

Chest infections, such as bronchitis and pneumonia.

Ear infections.

Mouth and dental infections.

Eye infections.

Skin and tissue infections, such as acne.

Stomach and intestinal infections.

Prevention of infection following burns, operations or dental

Other infections, such as sexually transmitted diseases,
bone infections or scarlet fever.
2. Before you take Erythrocin Tablets
You should not receive Erythrocin Tablets if you:

have been told that you are allergic to erythromycin or other
macrolide antibiotics such as clarithromycin or azithromycin
or any of the other ingredients in these tablets.

are currently taking a medicine called
− are taking ergotamine or dihydroergotamine (used to
treat migraines) while taking erythromycin as this may
cause serious side effects;
− are taking terfenadine or astemizole or mizolastine
(widely taken for hayfever and allergies), domperidone
(for nausea (feeling sick) and vomiting(being sick)),
cisapride (for stomach disorders) or pimozide or
amisulpride (for psychiatric conditions) while receiving
erythromycin, as combining these drugs can sometimes
cause serious disturbances in heart rhythm. Consult
your doctor for advice on alternative medicines you can
take instead;
− simvastatin (used to lower cholesterol and triglycerides
(types of fat) in the blood);
− tolterodine (used for treating overactive bladder with
symptoms of urinary frequency, urgency, and leakage);

are taking colchicine (used for treatment of gout and
arthritis) whilst taking erythromycin as this may cause
serious side effects;

have any liver problems or have been told that any drugs
you are taking can cause liver problems;

have previously experienced diarrhoea following the use of

are pregnant and have been told that you have a sexually
transmitted disease called syphilis. In this case erythromycin
may not be effective for preventing the transfer of this
infection to your baby. Consult your doctor before receiving
erythromycin. Alternatively if you were treated for early
stages of syphilis during your pregnancy, and your child is
under 1 year and is prescribed erythromycin, consult your
doctor before giving erythromycin to your child;

are treating a young child with antibiotics and they are
irritable or vomit when fed, you should contact your
physician immediately;

suffer from a condition called myasthenia gravis, which
causes muscle weakness, consult your doctor before
receiving erythromycin;

are taking erythromycin with ‘statins’ such as simvastatin or
lovastatin (used to lower cholesterol) as serious side effects
can occur.
If any of these apply to you, or if you are not sure, tell your
Taking other medicines
Please tell your doctor if you are taking, or have recently taken
any other medicines, including any medicines obtained without a
This is especially important if you are taking medicines from the
following families:

astemizole, terfenadine or mizolastine (used to treat
allergies such as hayfever);

domperidone (used to treat nausea (feeling sick) and
vomiting (being sick));

pimozide (used to treat mental problems);

ergotamine or dihydroergotamine (used to relieve migraine);

cisapride (used to treat stomach disorders);

statins (used to help lower cholesterol levels e.g. lovastatin
and simvastatin);

protease inhibitors (used to treat viral infections e.g.

oral contraceptives.
This is also important if you are taking medicines called:

colchicine (used to treat gout and arthritis);

cimetidine and omeprazole (used to treat acid reflux and
other related conditions);

clarithromycin, rifabutin, or rifampicin (medicines used to
treat different types of bacterial infection);

fluconazole, ketoconazole and itraconazole (medicines used
to treat fungal infections);

digoxin, quinidine or disopyramide (used to treat heart

cilostazol (a medicine used to treat peripheral circulation

hexobarbitone, phenobarbital or midazolam (used as

warfarin and acenocoumarol (used to help thin the blood);

valproate, carbamazepine or phenytoin (used to control

theophylline (used to treat asthma and other breathing

ciclosporin or tacrolimus (used following organ transplants);

bromocriptine (used to treat Parkinson’s disease);

zopiclone or triazolam/alprazolam (used to help you sleep or
relieve states of anxiety);

alfentanil (a medicine used to provide pain relief);

methylprednisolone (used to help suppress the body's
immune system – this is useful in treating a wide range of

St John’s Wort (a herbal medicine used to treat depression);

verapamil (used to treat high blood pressure and chest

vinblastine (used to treat certain types of cancer);

sildenafil (used to treat erectile dysfunction).
If you or your child goes for any medical tests, tell your doctor
that you are taking Erythrocin, as this may interfere with some
test results.
Pregnancy and breast-feeding
Erythromycin should be used by women during pregnancy only if
clearly needed.
If you are pregnant or think you may be pregnant, or if you are
breast-feeding, please consult your doctor before taking this

3. How to take Erythrocin Tablets
Always take Erythrocin Tablets exactly as your doctor has told
you. You should check with your doctor if you are not sure.
The usual dose of Erythrocin Tablets for adults and children over
8 years is:
1-2 g daily in divided doses i.e. four to eight 250 mg tablets daily
or two to four 500 mg tablets daily, taken just before or with
meals or food. If you have a bad infection you may be told to
take up to 4 g daily.
Continue to take this medicine until the course is completed or
until your doctor tells you to stop; do not stop taking your
medicine, even if you feel better. If you stop the treatment too
early your problem could come back.
If you take more Erythrocin than you should
If you accidentally take more medicine in one day than your
doctor has told you to, or if a child has taken some of the
medicine by mistake, contact your doctor or go to your nearest
hospital emergency department immediately. An overdose of
Erythrocin could cause temporary hearing loss, nausea, vomiting
and diarrhoea.
If you forget to take Erythrocin
If you forget to take a dose of your medicine, take it as soon as
you remember. Do not take more medicine in one day than your
doctor tells you to.
If you have any further questions on the use of this product ask
your doctor or pharmacist.
4. Possible side effects
Like all medicines, Erythrocin can cause side effects, although
not everybody gets them.
If you notice any of the following, contact your doctor

difficulty breathing;


swelling of the face, lips or throat;

skin rashes;

severe skin reactions including large fluid-filled blisters,
sores and ulcers;

ulcers in the mouth and throat, as these may be signs of an
allergic reaction.
Other side effects of Erythrocin include:

diarrhoea which may be severe or prolonged and may
contain blood or mucus;

feeling sick or being sick;

increase in a particular type of white blood cells

stomach pains; these may be a symptom of an inflamed
pancreas (pancreatitis);

ringing in the ears (tinnitus);

reversible loss of hearing (usually associated with high
doses or in patients with kidney problems);

various liver or gall-bladder problems, which can cause
yellowing of the skin and/or eyes (jaundice) or pale stools
with dark urine;

chest pains;

abnormal heart rhythms (including palpitations);




fits (seizures);

vertigo (problems with balance that can result in feelings of
dizziness or sickness – particularly on standing);

hallucinations (seeing or hearing things that aren’t there);

feeling generally unwell (malaise);

inflammation of the kidneys (a condition known as interstitial

low blood pressure;

serious skin rashes that may involve blistering and can
cover large areas of the torso, face and limbs (conditions
known as Stevens Johnson syndrome, toxic epidermal
necrolysis and erythema multiforme).

vomiting and irritability in young children between the age of
1 month and 12 months;

visual impairment/blurred vision (Mitochondrial optic

Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or
nurse. This includes any possible side effects not listed in this
leaflet. You can also report side effects directly via the Yellow
Card Scheme at: By reporting side
effects, you can help provide more information on the safety of
this medicine.
5. How to store Erythrocin Tablets
Do not store above 25°C.
Store in the original container.
Keep the container tightly closed.
Keep out of the sight and reach of children.
Do not use the tablets after the expiry date shown on the
container/outer carton. The expiry date refers to the last day of
the month.
If the tablets show any signs of discolouration or deterioration
consult your pharmacist for advice.
Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help to
protect the environment.
6. Further information
What Erythrocin Tablets contain
Each film-coated tablet contains: 250 mg erythromycin as
erythromycin stearate.
Also contains: hypromellose, maize starch, povidone,
magnesium hydroxide, sorbic acid, macrogol 400, macrogol
8000 and polacrilin potassium.
What Erythrocin Tablets look like and the contents of the
Erythrocin Tablets are white, oval-shaped film coated tablets
embossed with a logo on one side and plain on the other.
Erythrocin Tablets are available in containers of 100 tablets.
Manufactured by: Aesica Queenborough Limited,
Queenborough, Kent, ME11 5EL, UK. Procured from within the
EU. Product Licence holder: Quadrant Pharmaceuticals Ltd.
Lynstock House, Lynstock Way, Lostock, Bolton BL6 4SA.
Repackaged by Maxearn Ltd. Bolton BL6 4SA.
PL 20774/1339 - Erythrocin 250mg Tablets

Leaflet revision date: 5th July 2017

Blind or partially sighted?
Is this leaflet hard to see or read?
Contact Quadrant Pharmaceuticals
Ltd – 01204 473081
Erythrocin is a registered trademark of Amdipharm
International Limited.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.