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Erythrocin® 250mg Tablets
(erythromycin stearate)
Read all of this leaflet carefully before you start taking
this medicine.
 Please keep this leaflet. You may need to read it
 If you have any further questions, ask your doctor or
 This medicine has been prescribed for you. Do not
pass it on to others. It may harm them, even if their
symptoms are the same as yours.
 If any of the side effects become severe, or if you
notice any side effects not listed in this leaflet, please
tell your doctor or pharmacist.
The name of your medicine is Erythrocin 250mg Tablets
but will be referred to as Erythrocin Tablets or Erythrocin
throughout the remainder of the leaflet.
Erythrocin Tablets are also available in another strength
In this leaflet:
1. What Erythrocin Tablets are and what they are used
2. Before you take Erythrocin Tablets
3. How to take Erythrocin Tablets
4. Possible side effects
5. How to store Erythrocin Tablets
6. Further information.
1. What Erythrocin Tablets are and what they are used
The name of your medicine is Erythrocin Tablets.
Erythrocin contains the active ingredient erythromycin
which belongs to a group of medicines called macrolide
Erythrocin Tablets are used to prevent and treat infections
such as:
 Throat and sinus infections.
 Chest infections, such as bronchitis and pneumonia.
 Ear infections.
 Mouth and dental infections.
 Eye infections.
 Skin and tissue infections, such as acne.
 Stomach and intestinal infections.
 Prevention of infection following burns, operations or
dental procedures.
 Other infections, such as sexually transmitted
diseases, bone infections or scarlet fever.
2. Before you take Erythrocin Tablets
You should not receive Erythrocin Tablets if you:
 have been told that you are allergic to erythromycin or
other macrolide antibiotics such as clarithromycin or
azithromycin or any of the other ingredients in these
 are currently taking a medicine called
 are taking ergotamine or dihydroergotamine (used
to treat migraines) while taking erythromycin as
this may cause serious side effects;
 are taking terfenadine or astemizole or mizolastine
(widely taken for hayfever and allergies),
domperidone (for nausea (feeling sick) and
vomiting(being sick)), cisapride (for stomach
disorders) or pimozide or amisulpride (for
psychiatric conditions) while receiving
erythromycin, as combining these drugs can
sometimes cause serious disturbances in heart
rhythm. Consult your doctor for advice on
alternative medicines you can take instead;
 simvastatin (used to lower cholesterol and
triglycerides (types of fat) in the blood);
 tolterodine (used for treating overactive bladder
with symptoms of urinary frequency, urgency, and

are taking colchicine (used for treatment of gout and
arthritis) whilst taking erythromycin as this may cause
serious side effects;
have any liver problems or have been told that any
drugs you are taking can cause liver problems;
have previously experienced diarrhoea following the
use of antibiotics;
are pregnant and have been told that you have a
sexually transmitted disease called syphilis. In this
case erythromycin may not be effective for preventing
the transfer of this infection to your baby. Consult your
doctor before receiving erythromycin. Alternatively if
you were treated for early stages of syphilis during
your pregnancy, and your child is under 1 year and is
prescribed erythromycin, consult your doctor before
giving erythromycin to your child;
are treating a young child with antibiotics and they are
irritable or vomit when fed, you should contact your
physician immediately;
suffer from a condition called myasthenia gravis,
which causes muscle weakness, consult your doctor
before receiving erythromycin;
are taking erythromycin with ‘statins’ such as
simvastatin or lovastatin (used to lower cholesterol) as
serious side effects can occur.

If any of these apply to you, or if you are not sure, tell your
Taking other medicines
Please tell your doctor if you are taking, or have recently
taken any other medicines, including any medicines
obtained without a prescription.
This is especially important if you are taking medicines
from the following families:
 astemizole, terfenadine or mizolastine (used to treat
allergies such as hayfever);
 domperidone (used to treat nausea (feeling sick) and
vomiting (being sick));
 pimozide (used to treat mental problems);
 ergotamine or dihydroergotamine (used to relieve
 cisapride (used to treat stomach disorders);
 statins (used to help lower cholesterol levels e.g.
lovastatin and simvastatin);
 protease inhibitors (used to treat viral infections e.g.
 oral contraceptives.
This is also important if you are taking medicines called:
 colchicine (used to treat gout and arthritis);
 cimetidine and omeprazole (used to treat acid reflux
and other related conditions);
 clarithromycin, rifabutin, or rifampicin (medicines used
to treat different types of bacterial infection);
 fluconazole, ketoconazole and itraconazole
(medicines used to treat fungal infections);
 digoxin, quinidine or disopyramide (used to treat heart
 cilostazol (a medicine used to treat peripheral
circulation problems);
 hexobarbitone, phenobarbital or midazolam (used as
 warfarin and acenocoumarol (used to help thin the
 valproate, carbamazepine or phenytoin (used to
control epilepsy);
 theophylline (used to treat asthma and other breathing
 ciclosporin or tacrolimus (used following organ
 bromocriptine (used to treat Parkinson’s disease);
 zopiclone or triazolam/alprazolam (used to help you
sleep or relieve states of anxiety);
 alfentanil (a medicine used to provide pain relief);
 methylprednisolone (used to help suppress the body's
immune system – this is useful in treating a wide
range of conditions);

St John’s Wort (a herbal medicine used to treat
verapamil (used to treat high blood pressure and
chest pain);
vinblastine (used to treat certain types of cancer);
sildenafil (used to treat erectile dysfunction).

If you or your child goes for any medical tests, tell your
doctor that you are taking Erythrocin, as this may interfere
with some test results.
Pregnancy and breast-feeding
Erythromycin should be used by women during pregnancy
only if clearly needed.
If you are pregnant or think you may be pregnant, or if you
are breast-feeding, please consult your doctor before
taking this medicine.
3. How to take Erythrocin Tablets
Always take Erythrocin Tablets exactly as your doctor has
told you. You should check with your doctor if you are not
The usual dose of Erythrocin Tablets for adults and
children over 8 years is:
1-2 g daily in divided doses i.e. four to eight 250 mg
tablets daily or two to four 500 mg tablets daily, taken just
before or with meals or food. If you have a bad infection
you may be told to take up to 4 g daily.
Continue to take this medicine until the course is
completed or until your doctor tells you to stop; do not
stop taking your medicine, even if you feel better. If you
stop the treatment too early your problem could come
If you take more Erythrocin than you should
If you accidentally take more medicine in one day than
your doctor has told you to, or if a child has taken some of
the medicine by mistake, contact your doctor or go to your
nearest hospital emergency department immediately. An
overdose of Erythrocin could cause temporary hearing
loss, nausea, vomiting and diarrhoea.
If you forget to take Erythrocin
If you forget to take a dose of your medicine, take it as
soon as you remember. Do not take more medicine in one
day than your doctor tells you to.
If you have any further questions on the use of this
product ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Erythrocin can cause side effects,
although not everybody gets them.
If you notice any of the following, contact your doctor
 difficulty breathing;
 fainting;
 swelling of the face, lips or throat;
 skin rashes;
 severe skin reactions including large fluid-filled
blisters, sores and ulcers;
 ulcers in the mouth and throat, as these may be signs
of an allergic reaction.
Other side effects of Erythrocin include:
 diarrhoea which may be severe or prolonged and may
contain blood or mucus;
 feeling sick or being sick;
 increase in a particular type of white blood cells
 stomach pains; these may be a symptom of an
inflamed pancreas (pancreatitis);
 ringing in the ears (tinnitus);
 reversible loss of hearing (usually associated with high
doses or in patients with kidney problems);
 various liver or gall-bladder problems, which can
cause yellowing of the skin and/or eyes (jaundice) or
pale stools with dark urine;

chest pains;
abnormal heart rhythms (including palpitations);
fits (seizures);
vertigo (problems with balance that can result in
feelings of dizziness or sickness – particularly on
hallucinations (seeing or hearing things that aren’t
feeling generally unwell (malaise);
inflammation of the kidneys (a condition known as
interstitial nephritis);
low blood pressure;
serious skin rashes that may involve blistering and can
cover large areas of the torso, face and limbs
(conditions known as Stevens Johnson syndrome,
toxic epidermal necrolysis and erythema multiforme).

Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist
or nurse. This includes any possible side effects not listed
in this leaflet. You can also report side effects directly via
the Yellow Card Scheme at:
By reporting side effects, you can help provide more
information on the safety of this medicine.

5. How to store Erythrocin Tablets
Do not store above 25°C.
Store in the original container.
Keep the container tightly closed.
Keep out of the sight and reach of children.
Do not use the tablets after the expiry date shown on the
container/outer carton. The expiry date refers to the last
day of the month.
If the tablets show any signs of discolouration or
deterioration consult your pharmacist for advice.
Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help to
protect the environment.
6. Further information
What Erythrocin Tablets contain
Each film-coated tablet contains: 250 mg erythromycin as
erythromycin stearate.
Also contains: hypromellose, maize starch, povidone,
magnesium hydroxide, sorbic acid, macrogol 400,
macrogol 8000 and polacrilin potassium.

What Erythrocin Tablets look like and the contents of
the pack
Erythrocin Tablets are white, oval-shaped film coated
tablets embossed with a logo on one side and plain on the
Erythrocin Tablets are available in containers of 100
Manufactured by: Aesica Queenborough Limited,
Queenborough, Kent, ME11 5EL, UK. Procured from
within the EU. Product Licence holder: Quadrant
Pharmaceuticals Ltd. Lynstock House, Lynstock Way,
Lostock, Bolton BL6 4SA. Repackaged by Maxearn Ltd.
Bolton BL6 4SA.
PL 20774/1339 - Erythrocin 250mg Tablets

Leaflet revision date: 25th August 2016
Erythrocin is a registered trademark of Amdipharm
International Limited.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.