Active substance(s): ERYTHROMYCIN STEARATE
PATIENT INFORMATION LEAFLET ON
Read all of this leaflet carefully before you start
taking this medicine.
- Please keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or
- This medicine has been prescribed for you. Do not pass it
on to others. It may harm them, even if their symptoms are
the same as yours.
- If any of the side effects becomes severe, or if you notice
any side effects not listed in this leaflet, please tell your
doctor or pharmacist.
In this leaflet:
1. What Erythrocin® Tablets are and what they are
2. Before you take Erythrocin® Tablets
3. How to take Erythrocin® Tablets
4. Possible side effects
5. How to store Erythrocin® Tablets
6. Further information
1. WHAT ERYTHROCIN® TABLETS ARE AND WHAT THEY
ARE USED FOR
The name of your medicine is Erythrocin® Tablets.
Erythrocin® contains the active ingredient erythromycin which
belongs to a group of medicines called macrolide antibiotics.
Erythrocin® Tablets are used to prevent and treat infections
• Throat and sinus infections
• Chest infections, such as bronchitis and pneumonia
• Ear infections
• Mouth and dental infections
• Eye infections
• Skin and tissue infections, such as acne
• Stomach and intestinal infections
• Prevention of infection following burns, operations or
• Other infections, such as sexually transmitted diseases,
bone infections or scarlet fever
2. BEFORE YOU TAKE ERYTHROCIN
You should not receive Erythrocin Tablets if you:
• have been told that you are allergic to erythromycin or
other macrolide antibiotics such as clarithromycin or
azithromycin or any of the other ingredients in these
• are currently taking a medicine called
- are taking ergotamine or dihydroergotamine (used to
treat migraines) while taking erythromycin as this may
cause serious side effects;
- are taking terfenadine or astemizole or mizolastine
(widely taken for hayfever and allergies), domperidone
(for nausea (feeling sick) and vomiting (being sick)),
cisapride (for stomach disorders) or pimozide or
amisulpride (for psychiatric conditions) while receiving
erythromycin, as combining these drugs can sometimes
cause serious disturbances in heart rhythm. Consult
your doctor for advice on alternative medicines you can
- simvastatin (used to lower cholesterol and triglycerides
(types of fat) in the blood);
- tolterodine (used for treating overactive bladder with
symptoms of urinary frequency, urgency, and leakage);
• are taking colchicine (used for treatment of gout and
arthritis) whilst taking erythromycin as this may cause
serious side effects;
• have any liver problems or have been told that any drugs
you are taking can cause liver problems;
• have previously experienced diarrhoea following the use of
• are pregnant and have been told that you have a sexually
transmitted disease called syphilis. In this case erythromycin
may not be effective for preventing the transfer of this
infection to your baby. Consult your doctor before receiving
erythromycin. Alternatively if you were treated for early
stages of syphilis during your pregnancy, and your child is
under 1 year and is prescribed erythromycin, consult your
doctor before giving erythromycin to your child;
• are treating a young child with antibiotics and they are
irritable or vomit when fed, you should contact your physician
• suffer from a condition called myasthenia gravis, which
causes muscle weakness, consult your doctor before receiving
• are taking erythromycin with ‘statins’ such as simvastatin or
lovastatin (used to lower cholesterol) as serious side effects
If any of these apply to you, or if you are not sure, tell your
Taking other medicines
Please tell your doctor if you are taking, or have recently taken
any other medicines, including any medicines obtained without a
This is especially important if you are taking medicines from the
• astemizole, terfenadine or mizolastine (used to treat
allergies such as hayfever);
• domperidone (used to treat nausea (feeling sick) and
vomiting (being sick));
• pimozide (used to treat mental problems);
• ergotamine or dihydroergotamine (used to relieve
• cisapride (used to treat stomach disorders);
• statins (used to help lower cholesterol levels e.g. lovastatin
• protease inhibitors (used to treat viral infections e.g.
• oral contraceptives.
This is also important if you are taking medicines called:
• colchicine (used to treat gout and arthritis);
• cimetidine and omeprazole (used to treat acid reflux and
other related conditions);
• clarithromycin, rifabutin, or rifampicin (medicines used to
treat different types of bacterial infection);
• fluconazole, ketoconazole and itraconazole (medicines used
to treat fungal infections);
• digoxin, quinidine or disopyramide (used to treat heart
• cilostazol (a medicine used to treat peripheral circulation
• hexobarbitone, phenobarbital or midazolam (used as
• warfarin and acenocoumarol (used to help thin the blood);
• valproate, carbamazepine or phenytoin (used to control
• theophylline (used to treat asthma and other breathing
• ciclosporin or tacrolimus (used following organ transplants);
• bromocriptine (used to treat Parkinson’s disease);
• zopiclone or triazolam/alprazolam (used to help you sleep or
relieve states of anxiety);
• alfentanil (a medicine used to provide pain relief);
• methylprednisolone (used to help suppress the body's
immune system – this is useful in treating a wide range of
• St John’s Wort (a herbal medicine used to treat depression);
• verapamil (used to treat high blood pressure and chest
• vinblastine (used to treat certain types of cancer);
• sildenafil (used to treat erectile dysfunction).
If you or your child goes for any medical tests, tell your doctor
that you are taking Erythrocin®, as this may interfere with
some test results.
Pregnancy and breast-feeding
Erythromycin should be used by women during pregnancy only
if clearly needed.
If you are pregnant or think you may be pregnant, or if you are
breast-feeding, please consult your doctor before taking this
3. HOW TO TAKE ERYTHROCIN® TABLETS
Always take Erythrocin® Tablets exactly as your doctor has told
you. You should check with your doctor if you are not sure.
The usual dose of Erythrocin® Tablets for adults and children
over 8 years is:
1-2 g daily in divided doses i.e. four to eight 250 mg tablets
daily or two to four 500 mg tablets daily, taken just before or
with meals or food. If you have a bad infection you may be told
to take up to 4 g daily.
Continue to take this medicine until the course is completed or
until your doctor tells you to stop; do not stop taking your
medicine, even if you feel better. If you stop the treatment too
early your problem could come back.
If you take more Erythrocin® than you should
If you accidentally take more medicine in one day than your
doctor has told you to, or if a child has taken some of the
medicine by mistake, contact your doctor or go to your nearest
hospital emergency department immediately.
An overdose of Erythrocin® could cause temporary hearing
loss, nausea, vomiting and diarrhoea.
If you forget to take Erythrocin®
If you forget to take a dose of your medicine, take it as soon as
you remember. Do not take more medicine in one day than
your doctor tells you to.
If you have any further questions on the use of this product ask
your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Erythrocin® Tablets can cause side effects,
although not everybody gets them.
If you notice any of the following, contact your doctor
• difficulty breathing;
• swelling of the face, lips or throat;
• skin rashes;
• severe skin reactions including large fluid-filled blisters,
sores and ulcers;
• ulcers in the mouth and throat, as these may be signs of an
Contact a doctor immediately if you experience a serious skin
reaction: a red, scaly rash with bumps under the skin and blisters
(exanthematous pustulosis). The frequency of this side effect is
not known (cannot be estimated from the available data).
Other side effects of Erythrocin® include:
• diarrhoea which may be severe or prolonged and may
contain blood or mucus;
• feeling sick or being sick;
• increase in a particular type of white blood cells
• stomach pains; these may be a symptom of an inflamed
• ringing in the ears (tinnitus);
• reversible loss of hearing (usually associated with high doses
or in patients with kidney problems);
• various liver or gall-bladder problems, which can cause
yellowing of the skin and/or eyes (jaundice) or pale stools with
• chest pains;
• abnormal heart rhythms (including palpitations);
• fits (seizures);
• vertigo (problems with balance that can result in feelings of
dizziness or sickness – particularly on standing);
• hallucinations (seeing or hearing things that aren’t there);
• feeling generally unwell (malaise);
• inflammation of the kidneys (a condition known as interstitial
• low blood pressure;
• serious skin rashes that may involve blistering and can cover
large areas of the torso, face and limbs (conditions known as
Stevens Johnson syndrome, toxic epidermal necrolysis and
• vomiting and irritability in young children between the age of
1 month and 12 months;
• visual impairment/blurred vision (Mitochondrial optic
If you get any side effects, talk to your doctor or pharmacist. This
includes any possible side effects not listed in this leaflet. You can
also report side effects directly via the Yellow Card Scheme at:
By reporting side effects you can help provide more information
on the safety of this medicine.
5. HOW TO STORE ERYTHROCIN® TABLETS
Do not store above 25°C. Store in the original package.
Do not use these tablets after the expiry date shown on the
blister/label. The expiry date refers to the last day of that month.
KEEP OUT OF THE REACH AND SIGHT OF CHILDREN
Medicines should not be disposed of via waste water or household
waste. Ask your pharmacist how to dispose of medicines no longer
required. These measures will help to protect the environment.
6. FURTHER INFORMATION
What Erythrocin® Tablets contain
Each Erythrocin® 250 tablet contains 250 mg of the active
Each Erythrocin® 500 tablet contains 500 mg of the active
The other ingredients are: hydroxypropyl methyl cellulose, maize
starch, povidone, magnesium hydroxide, sorbic acid, polyethylene
glycol and polacrilin potassium.
What Erythrocin® Tablets look like and the contents of
Erythrocin® tablets are white.
The Erythrocin® 250 tablets are available in containers of 50, 100
or 1000 tablets, or blister packs of 28 tablets.
The Erythrocin® 500 tablets are available in containers of 50, 100
or 1000 tablets, or blister packs of 10, 14, 15, 28 or 56 tablets.
Marketing Authorisation Holder and Manufacturer
Marketing Authorisation Holder:
Amdipharm UK Limited,
Capital House, 85 King William Street, London EC4N 7BL, UK
Aesica Queenborough Limited,
Queenborough, Kent ME11 5EL, UK
This leaflet applies only to Erythrocin® and this leaflet was last
revised in December 2017.
Erythrocin® is a Registered Trademark.
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.