EPINEPHRINE (ADRENALINE) INJECTION 1:1000 MINIJET
Active substance(s): EPINEPHRINE
Package Leaflet: Information for the patient
1:1,000 Minijet 1mg/ml Solution
FOR ADMINISTRATION BY
Read all of this leaflet carefully
Please note this medicine is
mainly used in emergency
situations and the doctor will have
decided that you needed it.
It is unlikely therefore, that you
will have read this leaflet before
the medicine was administered
− Keep this leaflet. You may need
to read it again.
− If you have any further
questions, ask the doctor or
− If you get any side effects, talk
to your doctor or nurse. This
includes any possible side
effects not listed in this leaflet.
− In this leaflet, Adrenaline
1:1,000 Minijet 1mg/ml Solution
for Injection will be called
What is in this leaflet:
1. What Adrenaline Minijet is and
what it is used for
2. What you need to know before
you are given Adrenaline
3. How Adrenaline Minijet is used
4. Possible side effects
5. How to store Adrenaline Minijet
6. Further information.
1. What Adrenaline Minijet is
and what it is used for
Adrenaline is a type of drug that
constricts blood vessels, makes
the heart pump more strongly and
It is used in life-threatening
emergencies such as severe
allergic reactions or asthma. It
will have been used to save your
2. What you need to know
before you are given
In emergencies, it may be
impossible for the people looking
after you to get all your details
before they have to treat you. They
will have assessed the situation
and decided it was better to give
you the injection now and ask
Please tell your doctor if:
• You are allergic to any of the
ingredients in this medicine
(listed in section 6)
• You suffer from
• You suffer from hypertension
(high blood pressure)
• You suffer from heart disease or
long standing chest disease like
asthma or emphysema
• You suffer from diabetes
• You suffer from closed angle
glaucoma (an eye condition that
causes sudden blurred vision
with pain and redness)
You are allergic to
You have a problem with the
rate or rhythm of your heartbeat
You have had a spinal cord
injury and are suffering from
over-activity of the involuntary
nervous system which causes
your blood pressure to be
You are allergic to sulfites
You suffer from an enlarged
prostate or have difficulty
You have mental disturbances
You are going to have surgery
under a general anaesthetic.
Other medicines and
Tell your doctor if you are taking
or have recently taken any
In particular those:
• For heart problems or
high blood pressure (e.g.
propranolol, digoxin, quinidine,
guanethidine, alpha blockers or
sympathomimetic drugs such as
• For migraine (e.g. ergot
• For depression or other
psychiatric illness (e.g.
inhibitors (MAOIs), tricyclic
• For diabetes (e.g. glibenclamide)
• For post natal bleeding (e.g.
• For Parkinson’s disease (e.g.
• Drugs which cause potassium
• General anaesthetics (e.g.
Pregnancy and breast feeding
Tell your doctor if you are
pregnant as the heartbeat of the
unborn child can be affected.
However, it is safe to continue
Driving and using machines
Not applicable; this medicine is
intended for emergency use only.
Adrenaline Minijet contains
This medicinal product contains
less than 1 mmol sodium per ml
(3mg/ml), i.e. essentially ‘sodium
Sodium metabisulfite may rarely
cause hypersensitivity reactions
and bronchospasm (breathing
3. How Adrenaline Minijet is
This medicine will have been given to
you by a healthcare professional.
Adrenaline Minijet is given slowly
under the skin or into muscle.
Repeated injections should be given at
a different site on the body.
The following is a guide:
Adults and children over 12 years:
0.5 ml. The dose may be repeated
every 5 to 15 minutes as needed.
A lower dose may be used in the
Children under 12 years old:
If you think you have been given too
much medicine, please tell your
If you have any further questions on
the use of this medicine, ask your
doctor or nurse.
4. Possible Side-effects
Like all medicines this medicine
can cause side effects, although not
everyone gets them.
• Your heart may beat an odd rhythm
or you could have a heart attack
• Blood pressure may rise
dangerously high leading to stroke
or fluid in the lungs
• Extreme chest pain which does not
go away when you rest
• Stress which causes the symptoms
of a heart attack
• The cells of your bowel may die
• Cold fingers and toes
• Pallor, headache, dizziness,
breathlessness, shakiness, sweating
• A feeling of anxiety, fear,
restlessness, or weakness
• Feeling sick or being sick
• Difficulty urinating
• Your blood sugar levels may be
altered, making you feel ill
• Repeated injections may damage
Reporting of side effects
If you get any side effects, talk to your
doctor, pharmacist or nurse. This
includes any possible side effects not
listed in this leaflet. You can also
report side effects directly via:
HPRA Pharmacovigilance, Earlsfort
Terrace, IRL - Dublin 2;
Tel: +353 1 6764971;
Fax: +353 1 6762517.
Yellow Card Scheme
By reporting side effects, you can help
provide more information on the
safety of this medicine.
5. How to store Adrenaline
Keep this medicine out of the sight
and reach of children.
Do not use this medicine after the
expiry date which is stated on the
carton and syringe label. The expiry
date refers to the last day of that
Store below 25°C. Keep container in
outer carton in order to protect from
Do not use Adrenaline if you notice
that the solution has discoloured.
Discard any unused portion.
Medicines should not be disposed of
via waste water or household waste.
Ask your pharmacist how to dispose
of medicines no longer required.
These measures will help protect the
6. Contents of the pack and other
What Adrenaline Minijet contains
The active substance is adrenaline
(epinephrine) 1mg per ml.
The other ingredients are citric acid
monohydrate, sodium citrate (E331),
sodium chloride, sodium metabisulfite
(E223), hydrochloric acid (for pH
adjustment), water for injection.
What Adrenaline Minijet looks like
and contents of the pack
Adrenaline Minijet is a solution for
injection. The solution is clear and
colourless and is packed in a clear,
glass syringe. There is one syringe per
Marketing Authorisation holder:
International Medication Systems
(UK) Ltd., 21 St Thomas Street,
Bristol, BS1 6JS, UK
UCB Pharma Ltd, 208 Bath Road,
Slough, Berkshire, SL1 3WE, UK.
This leaflet was last revised
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.