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Active substance(s): BARIUM SULFATE

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E-Z-CAT (UK) PIL TX1216-7 CL89902 02-16_Layout 2/10/16 3:45 PM Page 1



4.9 % w/v oral suspension
barium sulfate

Read all of this leaflet carefully before you have this medicine.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor,
radiographer or nurse helping you with your examination
which is usually called a CT or CAT scan.
• If any of the side effects get serious, or if you notice any side
effects not listed in this leaflet, please tell your doctor,
radiographer or nurse helping you with your examination.

Talk to your doctor before you have E-Z-CAT if you:
• or members of your family suffer from allergies, hay fever,
eczema or asthma
• are elderly
• are feeling weak (debilitated)
• are a baby or small child
• suffer from narrowing of the bowel or stomach (stenosis)
• suffer from a condition known as ‘gastrointestinal fistulae’
• suffer from cancer of any part of the bowel
• suffer from inflammatory intestinal disease
• suffer from a condition known as ‘diverticulitis’ or
• suffer from an infection known as ‘amoebiasis’
• suffer from a condition called Hirschsprung’s Disease
• have ever suffered from aspiration (where you might breathe
in food or liquid into your lungs)
• find swallowing difficult
• have ever suffered from a stroke
• have kidney problems
• suffer from constipation
• are dehydrated
• suffer from heart disease.
If any of the above applies to you, talk to your doctor before you
have E-Z-CAT.

In this leaflet:
1. What E-Z-CAT is and what it is used for
2. Before you have E-Z-CAT
3. How E-Z-CAT will be given to you
4. Possible side effects
5. How to store E-Z-CAT
6. Further information

Using other medicines
Please tell your doctor, radiographer or nurse helping you with
your X-ray examination if you are taking or have recently taken
any other medicines, including medicines obtained without a

1. What E-Z-CAT is and what it is used for
E-Z-CAT belongs to a group of medicines called ‘contrast media’.
It is used when you have an examination called a CT or CAT scan
where X-rays are used. It contains a chemical that helps the
X-ray show up.
E-Z-CAT will be given to you as a drink.
This medicine is for diagnostic use only. It only helps to diagnose
a problem. It cannot be used to treat any diseases.

E-Z-CAT may interfere with the action of other medicines taken at
the same time.  Your doctor may separate the administration of
barium sulfate from that of your other medicines or other
digestive tract examinations.
Pregnancy and breast-feeding
Tell the doctor or nurse if you know that you are pregnant or you
are trying to become pregnant. X-rays can harm unborn babies so
you will only be given an X-ray if it is essential for you.
You can continue to breast feed if you take E-Z-CAT.
Driving and using machines
E-Z-CAT may cause you to feel dizzy. If this happens to you, do
not drive or use machinery until this effect has worn off.

2. Before you have E-Z-CAT
Do not have E-Z-CAT if you:
• are allergic (hypersensitive) to barium sulfate or any of the
other ingredients of E-Z-CAT (see section 6)
• know that you have a hole or blockage in your bowel or
stomach (gastrointestinal perforation or obstruction)
• know that you have an abnormal passage connecting your
stomach with your bowel (gastrointestinal fistula)
• suffer from bleeding in your bowel or stomach
• suffer from insufficient blood supply (ischaemia) of the bowel
• have an enlarged bowel - a condition called megacolon or
toxic megacolon
• have an inflamed condition of the bowel called necrotising
• suffer from severe constipation
• suffer from a stomach condition called impaired gastric
• are a baby and have problems swallowing
• have recently had bowel surgery, such as a procedure called
‘hot’ colonic biopsy or snare polypectomy
• have had radiotherapy (cancer treatment) to your large bowel
(rectum) or prostate gland within the last 4 weeks
• have suffered recent injury to your bowel or stomach,
including chemical burns.

Important information about some of the ingredients of E-Z-CAT
E-Z-CAT contains sorbitol which may have a mild laxative effect.
The calorific value of sorbitol is 2.6 kcal/g. If you have been told
by your doctor that you have an intolerance to some sugars,
contact your doctor before taking this medicinal product.
It also contains approximately 206 mg sodium per 225 mL dose.
Please tell your doctor, radiographer or nurse if you are on a low
sodium (salt) diet.
E-Z-CAT also contains approximately 50 mg potassium per
225 mL dose. Please tell your doctor, radiographer or nurse if
you have kidney problems (reduced renal function) or are on a
low potassium diet.
It also contains methyl parahydroxybenzoate (E218) that can
cause allergic reactions, possibly delayed.
Ask your doctor if one of the above warnings is applicable to
you, or has been in the past.

If any of the above applies to you, you should not be given
E-Z-CAT. You should talk to your doctor again.


Rev. 02/16



4.9 % w/v oral suspension
barium sulfate
The following information is intended for medical or healthcare
professionals only:
It supplements the information provided in the package
leaflet above.

Children: The dosage will be dependent on the size, age, health
state and anatomical region to be imaged of the child. Individual
requirements should be determined, from experience, by
the radiologist.

Posology and method of administration

Special precautions for disposal and other handling

E-Z-CAT is for oral administration.

Shake well before use. E-Z-CAT is intended for dilution prior to
administration. Pour the contents into a litre container. Add water
to give a total volume of 900 mL. Shake well to yield 900 mL of
1.2 % w/v barium sulfate suspension. Alternatively, E-Z-CAT may
be mixed to yield a different density:-

The suspension is diluted with water to obtain a desired
concentration. Recommended dilutions are shown below in
section ‘Special precautions for disposal and other handling’.
Adults and the Elderly: 350 - 450 mL of diluted suspension
30 minutes prior to the scan and the same volume 5 minutes
prior to the scan, or, as directed by the physician.

E-Z-CAT (UK) PIL TX1216-7 CL89902 02-16_Layout 2/10/16 3:45 PM Page 2

3. How E-Z-CAT will be given to you
Adults, the elderly and children: Your doctor determines how
much E-Z-CAT is used.
E-Z-CAT will be given to you as a drink.
If you are dehydrated, prone to suffering from constipation or
elderly you may be offered a laxative before you use E-Z-CAT.
After your examination, you may be given a drink, laxative or put
on a saline drip.

Other possible side effects:
• high blood sugar (hyperglycaemia) in diabetics
• agitation, confusion or nervousness whilst the product is
being administered
• feeling dizzy
• swollen eyes
• tinnitus (ringing in the ears)
• low blood pressure
• problems passing urine
• feeling unwell, pain including headache, fever
• swelling, weakness, muscle or speech problems.
If any of the side effects gets serious, or if you notice any side
effects not listed in this leaflet, please tell your doctor.

4. Possible side effects
5. How to store E-Z-CAT
Like all medicines, E-Z-CAT can cause side effects, although not
everybody gets them.

E-Z-CAT should be kept out of the reach and sight of children.
Do not use E-Z-CAT after the expiry date which is stated on the
packaging behind the word ‘EXP’. The expiry date refers to the
last day of that month.

Seek immediate medical help if you have any of the following
• feeling faint or loss of consciousness
• swelling of the face or throat
• difficulty in breathing or wheezing, shortness of breath.

Your doctor or nurse will make sure your medicine is correctly
stored and disposed of.

These are the signs of a severe and sometimes life threatening
allergic reaction, such as shock.
6. Further information

The following side effects can also develop when you are given
this type of medicine:

What E-Z-CAT contains

Skin problems:
• itching
• redness
• rash
• sweating
• pale, clammy skin
• skin turning a blue or purple colour due to poor circulation.

• The active ingredient is barium sulfate 4.9 % w/v.
• The other ingredients are sorbitol, liquid (crystallising) (E420),
pectin (E440), xanthan gum (E415), simeticone emulsion,
sodium citrate (E331), citric acid (E330), potassium sorbate
(E202), methyl parahydroxybenzoate (E218), liquid orange
flavour, saccharin sodium (E954), sodium carrageenan (E407),
polyoxyyethylene glyceryl mono-oleate, purified water.

Stomach/bowel problems:
• constipation
• blocked bowel (the blockage would have to be removed by a
• diarrhoea
• feeling sick or being sick
• stomach pain or a bloated stomach
• excess wind (flatulence)
• bowel inflammation, ulceration or perforation (a hole)
• swollen tongue
• a damaged bowel wall lining which may lead to bacteria in
the blood, an abscess or appendicitis. You may be given
antibiotics to prevent this.
• in rare cases an enema may damage the lining of the bowel
wall. When this happens, it may result in an infection of the
bowel or its lining (peritonitis), or a type of swelling called
• small amounts of barium sulfate may leak into the blood
supply and end up in other parts of the body such as blood
vessels or arteries. This occurs rarely, but the result can be
very serious and may cause death.
• if you suffer from ulcerative colitis (inflammation of the
bowel), E-Z-CAT may aggravate your condition.

What E-Z-CAT looks like and contents of the pack
E-Z-CAT is a white, milky, viscous oral suspension. It is supplied
in bottles containing 225 mL E-Z-CAT.
Marketing Authorisation Holder
Bracco Imaging spa,
Via Egidio Folli 50, 20134 Milano, Italy
Manufacturer responsible for batch release
Bracco UK Limited,
Wooburn Green, Bucks, HP10 0HH, UK

If this leaflet is difficult to see or read, and you
would like it in a different format, please
contact Bracco UK Limited, Wooburn Green,
Bucks, HP10 0HH, UK.
This leaflet was last approved in May 2016.

Heart problems:
• changes in heart rhythm.
Respiratory problems:
When E-Z-CAT is taken as a drink, there is a small risk that you
could breathe it in. This may lead to:
• difficulty breathing
• cough and sore throat
• pneumonia which can result in death. This is very rare.


4.9 % w/v oral suspension
Barium sulfate
Pour E-Z-CAT contents into mixing container:-

Special precautions for storage


Add water to 700 mL. Yield a 1.6 % w/v suspension.


Add water to 600 mL. Yield a 1.8 % w/v suspension.

This medicinal product does not require any special storage


Add water to 500 mL. Yield a 2.2 % w/v suspension.

Do not freeze.

This pack is for single-dose use only. E-Z-CAT should be
administered immediately following dilution and must not
be stored.

Any unused, opened product or waste material should be
disposed of in accordance with local requirements.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.