CUPLEX VERRUCA GEL
Active substance(s): LACTIC ACID / SALICYLIC ACID
Read all of this leaflet carefully before you
start using this medicine.
• This medicine is available without
prescription. However, you still need to
use it carefully to get the best results
• Keep this leaflet. You may need to read it
• If you have any further questions, ask
your doctor or pharmacist.
• If any of the side effects get serious, or if
you notice any side effects not listed in
this leaflet, please tell your doctor or
In this leaflet:
1. What Cuplex Verruca Gel is and what it is used for.
2. Before you use Cuplex Verruca Gel.
3. How to use Cuplex Verruca Gel.
4. Possible side effects.
5. How to store Cuplex Verruca Gel.
6. Further information.
1. WHAT CUPLEX VERRUCA GEL IS
AND WHAT IT IS USED FOR
Cuplex Verruca Gel is a treatment for calluses,
corns, verrucas and warts.
Warts and verrucas are small excessive
growths of skin caused by a type of virus.
Warts often occur on the fingers, or on the
back of the hands. You can recognise the
common wart by the rough ‘cauliflower-like’
appearance of the surface. Verrucas occur
only on the sole of the foot. They can be
painful, and often look like a small white ring
of skin with black dots in the centre. The virus
is very infectious. This means that warts and
verrucas can grow and spread, particularly
if left untreated. The virus can also be
transferred from one person to another.
Corns and calluses are hard, thick pads of
skin caused by pressure and friction. They
usually occur on the feet due to poorly fitting
shoes. They can also occur on the hands.
Cuplex Verruca Gel is suitable for use by adults,
the elderly and children aged over 2 years.
Children under 12 should be treated under
supervision and treatment of infants under 2
years is not recommended.
The active ingredients in this product are salicylic
acid and lactic acid, they work by softening the
hard skin growth, making it easier to remove
with a pumice stone or emery board and help to
kill the virus that causes warts and verrucas.
2. BEFORE YOU USE CUPLEX
Do not use Cuplex Verruca Gel
• if you are allergic (hypersensitive) to salicylic
acid, lactic acid or to any of the other ingredients
of Cuplex Verruca Gel. (See Section 6)
• if you are diabetic or suffer from poor blood
circulation to your hands or feet
• anywhere on or near your face, armpits,
breasts, bottom or genital (sex) area.
• on birthmarks, moles (especially pigmented
moles), warts with hairs growing from them,
facial warts or any other spots.
If you are unsure whether you have a callus,
corn, verruca or wart that is suitable for
treatment with Cuplex Verruca Gel, ask your
doctor or pharmacist before starting treatment.
Take special care when using Cuplex Verruca Gel
Apply Cuplex Verruca Gel carefully to the callus,
corn, verruca or wart only by squeezing the tube
• it is important that the gel is only put onto the
callus, corn, verruca or wart and not on to the
surrounding healthy skin. If Cuplex Verruca Gel
is in contact with normal healthy skin for any
length of time it can cause irritation or pain.
• do not apply excessive amounts of gel.
• keep the gel away from your eyes, nose and
mouth and from broken skin, cuts and grazes.
• avoid spillage as this may cause damage to you,
your clothing and your possessions (see
• do not fold the tube because this may damage
it and make it leak.
• the gel is volatile and highly flammable. Do
not use it near flames or ignition sources.
• avoid inhaling the vapour from the gel.
Taking other medicines
This product is not known to affect, or to be
affected by, any other medicines.
Pregnancy and breast-feeding
Ask your doctor or pharmacist for advice before
using this medicine.
Driving and using machinery
Using this product is not known to affect your
ability to drive or use machinery.
3. HOW TO USE CUPLEX
Cuplex Verruca Gel is for external use only and
must not be taken by mouth.
Use Cuplex Verruca Gel only on calluses, corns,
verrucas or warts on sites that it is recommended
Cuplex Verruca Gel is suitable for use in all ages,
except in infants (under 2 years of age).
To use the gel
Follow these steps once every day, usually in the
evening. Carry on using the gel in this way until
the callus, corn, verruca or wart disappears.
The top of the tube is sealed to prevent it being
tampered with. Use the spike in the top of the cap
to pierce this seal when you first use it.
1. Soak the callus, corn, verruca or wart in
warm water for 2-3 minutes.
2. Dry the area thoroughly with your own
towel; this towel should be used only by you
for the affected site(s) only.
3. Carefully apply one or two drops of Cuplex
Verruca Gel to the callus, corn, verruca or
wart only and allow to dry over the surface. It
will form a water resistant clear brown film
over the affected site.
4. Take care to avoid spreading on to
surrounding normal healthy skin. If you use
too much gel, wipe off any excess with a
tissue, if necessary wash the area. No
sticking plaster is required.
5. The next evening remove the clear brown
film and re-apply. Repeat steps 1 to 3 to
re-apply the gel.
6. If removal of the clear brown film is difficult,
carefully re-apply directly over it and leave it
7. Once every week, rub away the callus, corn,
verruca or wart surface carefully with an
emery board or pumice stone. Do not let
anyone else use the emery board or pumice
stone as this may spread the infection to them.
8. Replace the cap on the tube tightly and wash
your hands thoroughly after using the gel.
It is important that you use Cuplex Verruca Gel
regularly and correctly every night. The length of
treatment will depend on the size and resistance of
the callus, corn, verruca or wart.
• Be patient, it will take between 6 and 12 weeks for
most calluses, corns, verrucas or warts to disappear.
• It is important you do not give up on the
treatment until the callus, corn, verruca or wart
has disappeared (unless irritation occurs, see
• At the end of treatment, if the clear brown film
is difficult to remove, you can leave it and it will
eventually fall off.
If the callus, corn, verruca or wart gets worse or has
not disappeared after about 12 weeks of treatment
ask your doctor for advice.
If Cuplex Verruca Gel
• gets in to your eyes or mouth it may cause harm.
Rinse the eyes or mouth with plenty of water.
If rinsing one eye take care to avoid rinsing
product into the other eye. Do not attempt to
induce vomiting. Contact your doctor or local
hospital for further advice.
• is inhaled, it may make you feel light headed. If
this happens get plenty of fresh air.
If you forget to use Cuplex Verruca Gel do not
worry, use it when you remember.
If you have any further questions on the use of this
product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Cuplex Verruca Gel can cause
side effects although not everybody gets them:
• while the gel is working you may feel a slight
tingling sensation and/or some mild tenderness
at the treated area. This is usually temporary,
and in rare cases may appear as a temporary
blemish on the skin.
If you mistakenly allow the gel to spread onto
and remain in contact with areas of normal skin
(see precautions in Section 2), it may cause
If you spill the product on your clothes, fabrics,
jewellery or metal and polished surfaces it may
damage them permanently.
Stop using this product and tell your doctor
or pharmacist if you experience unacceptable
discomfort or if irritation continues, or if any of the
side effects get serious, or you notice any other side
effects not mentioned in this leaflet.
Reporting of side effects
If you get any side effects, talk to your doctor or
pharmacist. This includes any possible side effects
not listed in this leaflet. You can also report side
effects directly via www.mhra.gov.uk/yellowcard.
By reporting side effects you can help provide more
information on the safety of this medicine’
5. HOW TO STORE CUPLEX
Keep Cuplex Verruca Gel out of the reach and sight
Do not use Cuplex Verruca Gel after the expiry date
which is stated on the tube and carton after the
abbreviation used for expiry date (EXP). The expiry
date refers to the last day of that month.
Do not store above 25ºC. Do not allow it to freeze.
Always replace cap tightly after use.
This product is highly flammable. Keep it away
from naked flames or ignition sources.
Medicines should not be disposed of via wastewater
or household waste. Ask your pharmacist how to
dispose of medicines no longer required. These
measures will help to protect the environment.
6. FURTHER INFORMATION
What Cuplex Verruca Gel contains
The name of your medicine is Cuplex Verruca Gel
and it contains 11% w/w Salicylic acid and 4% w/w
Lactic acid as the active ingredients. The other
ingredients are venice turpentine, colophony,
collodion and ethanol (96%).
What Cuplex Verruca Gel looks like and contents
of the pack
Cuplex Verruca Gel is a clear, yellowish brown gel.
Cuplex Verruca Gel is available in 5g tubes.
Marketing Authorisation Holder:
Crawford Healthcare Ltd, King Edward Court,
King Edward Road, Knutsford, Cheshire WA16 0BE.
A/S Den norske Eterfabrikk, Karihaugveien 22,
1086 Oslo, Norway.
This leaflet was last approved in: February 2015.
To listen to an audio version of this
leaflet, or request a copy in large
print, please call 01565 654920
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.