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Package Leaflet - Information for the User
CILOXAN® 3 mg / g eye ointment
Read all of this leaflet carefully before you start using this medicine

Keep this leaflet. You may need to read it again.

If you have any further questions, ask your doctor or your pharmacist.

This medicine has been prescribed for you. Do not pass it on to others. It may harm them,
even if their symptoms are the same as yours.

If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet,
please tell your doctor or pharmacist.


What CILOXAN is and what it is used for
Before you use CILOXAN
How to use CILOXAN
Possible side effects
How to store CILOXAN
Further information

CILOXAN is one of a group of medicines called quinolone antibiotics. It works by killing the germs
which have caused the infection in the eye.
CILOXAN is used to treat infections on the outside of the eye.


Do not use CILOXAN...
 If you are allergic (hypersensitive) to ciprofloxacin, other quinolone antibiotics or any of
the other ingredients listed in section 6.
 In CHILDREN under 1 year of age unless explicitly prescribed by your doctor.
Ask your doctor for advice.
Take special care...
 Only use CILOXAN in your eyes.
 If you notice the first signs of a skin rash or any other allergic reaction, including hives,
itching, breathing problems, stop treatment and immediately contact your doctor. If you have a
serious allergic reaction then you may need emergency treatment.
 If your symptoms get worse or suddenly return, consult your doctor. You may become more
susceptible to other infections with the use of this medicine, especially after prolonged use.
 If you are elderly or if you are taking medicines called ‘corticosteroids’ used to treat
conditions such as pain and inflammation, asthma or skin problems then, you have a higher
risk of getting tendon problems during treatment with CILOXAN. If you experience any
inflammation or inflammatory condition stop treatment and immediately consult your doctor.
 If you feel pain, swelling or inflammation of the tendons while or shortly after taking this
medicine, stop treatment and contact your doctor.
 As with any antibiotic, use of CILOXAN for a long time may lead to other infections. If
your symptoms get worse or suddenly return tell your doctor.
 Do not wear contact lenses (hard or soft) during treatment with CILOXAN.


Pregnancy and breast-feeding
If you are pregnant or might get pregnant, or if you are breast-feeding a baby, talk to your doctor
before you use CILOXAN.
Driving and using machines
You may experience blurred vision after using CILOXAN. Do not drive or use any machines unless
your vision is clear.
Using other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines,
including medicines obtained without a prescription.
If you are using eye drops as well as eye ointments, you should use the drops first. Leave a gap of at
least five minutes between using the drops and using the ointment.


The usual dose
Corneal Ulcer: Apply ointment every 1-2 hours around the clock for 2 days, then every 4 hours for a
further 12 days.
Bacterial Conjunctivitis and Blepharitis : Apply ointment 3 times per day for 2 days, then twice per
day for 5 additional days.
It is important that you continue to use CILOXAN for the full treatment period as advised by your
doctor, even if your symptoms improve. If you stop using this medicine too early, your symptoms may
Always use CILOXAN exactly as your doctor has told you. You should check with your doctor or
pharmacist if you are not sure.
Continued over >
HOW TO USE CILOXAN® (continued)


How to use
 Wash your hands before you start.
 Remove the cap from the tube.
 Tilt your head back.
 Pull down your lower eyelid with a finger, until there is a ‘pocket’ between the eyelid and
your eye. The ointment will go in here (picture 1).

Bring the ointment tube close to the eye. Do this in front of a mirror if it helps.
Do not touch your eye or eyelid, surrounding areas or other surfaces with the tip of the tube.
It could infect the ointment.
Gently squeeze a small ribbon of ointment (about 1.25 cm long) into the pocket formed
between your lower eyelid and your eye (picture 2).


Release the lower eyelid and blink a few times.
If you use ointment in both eyes, repeat the steps for your other eye. Replace and tightly close
the cap on the tube.

If you forget to use CILOXAN, do not worry. Apply the missed dose as soon as you
remember. If it is almost time for your next dose, skip the missed dose and continue with your
regular routine. Do not use a double dose to make up.
If you use more CILOXAN than you should rinse it all out with lukewarm water.
If this medicine is accidentally swallowed, it is not likely to cause any serious problems, but
contact your doctor.

If you have any further questions on the use of CILOXAN, ask your doctor or pharmacist.


Like all medicines, CILOXAN can cause side effects, although not everybody gets them.

You may experience some or all of the following effects in your eye(s) :

Common (affects 1 to 10 people in 100):
Discomfort (stinging or burning, gritty feeling in the eye, irritation), white deposits on eye surface
(cornea), redness.
Uncommon (affects 1 to 10 people in 1000):
Damage to the eye surface ( cornea ), blurred vision, swelling of the eye or eyelid, itching, dry eye,
discharge, eyelid crusting, eyelid scales, eyelid redness, red eyes, poor vision, pain, watery eyes,
sensitivity to light.
Rare (affects 1 to 10 people in 10000):
Eye inflammation, double vision, decreased eye sensation, tired eyes, stye.
If you notice white particles in your eyes, continue to use CILOXAN but tell your doctor

You may also experience effects in other areas of your body including:

Common : Bad taste.
Uncommon : Headache, nausea.
Rare : Hypersensitivity, dizziness, ear pain, inflammation inside the nose, nasal sinus discharge,
diarrhoea, abdominal pain, skin inflammation, tendon disorder.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme
at: By reporting side effects you can help provide more information on
the safety of this medicine.


Keep out of the reach and sight of children.
Do not store above 25 °C.


Keep the tube tightly closed.
Do not use the ointment after the expiry date (marked ‘Exp’) on the tube and the carton. The
expiry date refers to the last day of that month.
Stop using the tube 4 weeks after first opening, to prevent infections.
Medicines should not be disposed of via waste water or household waste. Ask your pharmacist
how to dispose of medicines no longer required. These measures will help to protect the
Do not pass this medicine on to others. It may harm them, even if their symptoms are the same
as yours.

What CILOXAN contains
 The active substance is ciprofloxacin hydrochloride, equivalent to 3 mg/g of ciprofloxacin.
 The other ingredients are liquid paraffin, white soft paraffin.
What CILOXAN looks like and contents of the pack
CILOXAN is a white to off-white ointment supplied in a pack containing a 3.5 g metal tube with a
screw cap.
Marketing authorisation holder :
Novartis Pharmaceuticals UK Limited
Frimley Business Park
GU16 7SR
United Kingdom.
Manufacturer :
SA Alcon-Couvreur NV
Rijksweg 14, B-2870 Puurs, Belgium.
This leaflet was last revised in 03 2017
Alcon a Novartis company


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Further information

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