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Pregnancy and breast-feeding

If you are pregnant or might get pregnant, or if you are breast-feeding a baby, talk to your doctor
before you use Ciloxan.

(ciprofloxacin (as hydrochloride))

Driving and using machines

If your sight is temporarily blurred or affected in any way following use of Ciloxan you should not
drive or operate machinery until your vision is clear again.

Your medicine is available using the name Ciloxan 0.3% Eye Drops Solution but will be referred to as
Ciloxan throughout this leaflet.

Using other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines,
including medicines obtained without a prescription.
If you are using more than one type of eye medicine, the medicines must be used at least 5 minutes
apart. Eye ointments should be used last.

Read all of this leaflet carefully before you start using this medicine.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or your pharmacist.
• This medicine has been prescribed for you. Do not pass it on to others. It may harm them,
even if their symptoms are the same as yours.
• If any of the side effects get serious, or if you notice any side effects not listed in this
leaflet, please tell your doctor or pharmacist.


Important information if you wear Contact Lenses

There is a preservative in Ciloxan (benzalkonium chloride) that may cause eye irritation and can
discolour soft contact lenses. Do not wear contact lenses (hard or soft) during treatment with Ciloxan.
If you do continue to wear your lenses, you must remove them before using Ciloxan and wait at least
15 minutes after use before putting your lenses back in.

this leaflet:
What Ciloxan is and what it is used for
Before you use Ciloxan
How to use Ciloxan
Possible side effects
How to store Ciloxan
Further information






The usual dose

This will depend on whether you are being treated for corneal ulcers or for some other bacterial
infection in your eye.

Corneal Ulcers
Dosing is continued during the night time.
Day 1 - 2 drops every 15 minutes for the first 6 hours and then 2 drops every 30 minutes.
Day 2 - 2 drops every hour.
Day 3 to Day 14 - 2 drops every 4 hours.
Your doctor will tell you if treatment needs to be continued for longer than 14 days.

Ciloxan belongs to a group of medicines known as quinolone antibiotics.
It is used for the treatment of corneal ulcers and some other bacterial infections of the eye(s).

Other bacterial infections

1 or 2 drops 4 times a day. For severe infections the dose for the first 2 days may be increased to 1 or
2 drops every 2 hours, while you are awake. It is important that you continue to use Ciloxan for the
full treatment period as advised by your doctor even if your symptoms improve. If you stop using
this medicine too early, your symptoms may re-occur.

Do not use Ciloxan…

If you are allergic (hypersensitive) to ciprofloxacin or any other quinolone antibiotic or to
any of the other ingredients listed in section 6.
Ask your doctor for advice.

Take special care…

You should not use Ciloxan for more than 21 days, unless your doctor says otherwise.

Only use Ciloxan in your eyes.
Only use Ciloxan in children younger than 1 year if prescribed by your doctor.
As with any antibiotic, use of Ciloxan for a long time may lead to other infections. If your
symptoms get worse or suddenly return tell your doctor. You may become more susceptible to
other infections with the use of this medicine, especially after prolonged use.
If you notice the first signs of a skin rash or any other allergic reaction, including hives, itching,
breathing problems stop treatment and immediately contact your doctor. If you have a serious
allergic reaction then you may need emergency treatment.
If you feel pain, swelling or inflammation while or shortly after taking this medicine, stop treatment
and contact your doctor.
If you are elderly or if you are taking medicines called 'corticosteroids' used to treat conditions
such as pain and inflammation, asthma or skin problems then you have a higher risk of getting
tendon problems during treatment with Ciloxan. If you experience any inflammation or
inflammatory condition, stop treatment and immediately consult your doctor.

Remove the loose collar from the cap when the bottle is first opened.
Always use Ciloxan exactly as your doctor has told you. You should check with your doctor or
pharmacist if you are not sure.

How to use

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Wash your hands before you start.
Twist off the bottle cap.
Hold the bottle pointing down, between your thumb and fingers.
Tilt your head back.
Pull down your lower eyelid with a finger, until there is a “pocket” between
the eyelid and your eye. The drop will go in here (picture 1).
Bring the bottle tip close to the eye. Do this in front of a mirror if it helps.
Do not touch your eye or eyelid, surrounding areas or other surfaces
with the dropper. It could infect the drops.
Gently press on the base of the bottle to release one drop at a time
(picture 2).
Do not squeeze the bottle, only a gentle press on the bottom is needed.

If you use drops in both eyes, repeat the steps for your other eye. Put the bottle cap firmly back
on immediately after use.
If a drop misses your eye, try again.
If you forget to use Ciloxan, do not worry, just use it when it is next due. Do not take a
double dose to make up.
If you use more Ciloxan than you should it can be washed out of your eye with lukewarm
If this medicine is accidentally swallowed, it is not likely to cause any serious problems, but
contact your doctor.



What Ciloxan contains

Ciloxan is supplied as a sterile solution in a 5ml dropper bottle containing 3.5mg of ciprofloxacin
hydrochloride (equivalent to 3.0mg of ciprofloxacin) in every ml of solution.
Other ingredients include sodium acetate, acetic acid, mannitol, edetate disodium and purified water.
It also contains 0.06mg of benzalkonium chloride in each ml of solution as a preservative.

If you have any further questions on the use of Ciloxan, ask your doctor or pharmacist.

Hydrochloric acid and/or sodium hydroxide may also be included in very small quantities to adjust the
acidity or alkalinity of the product to ensure comfort of the product in the eye.


What Ciloxan looks like and contents of the pack


Like all medicines, Ciloxan can cause side effects, although not everybody gets them.

Ciloxan is supplied in a 5ml dropper bottle as a clear and colourless to pale yellow solution.

You may experience some or all of the following effects in your eye(s):


Common (1 to 10 users in 100): White deposits on the eye surface (cornea), discomfort

(stinging or burning, gritty feeling in the eye, irritation), redness.
Uncommon (1 to 10 users in 1,000): Damage to the eye surface (cornea), sensitivity to light,
blurred vision, swelling of the eye or eyelid, pain, dry eye, itchiness, eye discharge, eyelid crusting,
eyelids scales, eyelid redness, poor vision, watery eyes, red eyes.
Rare (1 to 10 users in 10,000): Damage of the eye, inflammation, double vision, decreased
eye sensation, tired eyes, stye.

Your medicine is manufactured by: Laboratoires Alcon Cusi, E-08320 El Masnou, Barcelona, Spain.
Procured from within the EU and repackaged by: Doncaster Pharmaceuticals Group Ltd., Kirk Sandall,
Doncaster, DN3 1QR.
Product Licence holder: Landmark Pharma Ltd., 7 Regents Drive, Prudhoe, Northumberland, NE42 6PX.
PL No: 21828/0140

If you notice white particles in your eyes, continue to use Ciloxan but tell your doctor immediately.


You may also experience effects in other areas of your body including:
Common: Bad taste.
Uncommon: Headache, nausea.
Rare: Hypersensitivity, dizziness, ear pain, inflammation inside the nose, nasal sinus discharge,
diarrhoea, abdominal pain, skin inflammation, tendon disorder.


is a registered trademark of Alcon, Inc.

Leaflet revision date: 11.03.15

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side
effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at:
By reporting side effects you can help provide more information on the safety of this medicine.
If you experience an allergic reaction, stop using Ciloxan and tell your doctor.



Keep all medicines out of the sight and reach of children.
Do not store above 25°C.
Keep the container tightly closed.
Do not use after the expiry date printed on the carton or bottle. The expiry date refers to the last
day of that month. The medicine must be discarded one month after first opening.
Medicines should not be disposed of via waste water or household waste. Ask your pharmacist how
to dispose of medicines no longer required. These measures will help to protect the environment.
If your doctor decides to stop treatment, please take the eye drops back to the pharmacist for safe
disposal. Only keep the medicine if your doctor tells you to.
If the medicine become discoloured or show signs of deterioration, take them to your pharmacist
who will advise you.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.