CHILDRENS COUGH EXPECTORANT
NAME OF THE MEDICINAL PRODUCT
Ipecacuanha and Squill Linctus Paediatric BPC or Childrens Cough
Asda Children’s Chesty Cough Syrup
QUALITATIVE AND QUANTITATIVE COMPOSITION
Ipecacuanha Tincture BP 2.0% v/v
Squill Tincture BP 3.0% v/v
As an expectorant.
Posology and method of administration
5 ml to be taken three times daily.
Route of administration
Impaired renal function, impaired hepatic function, cardiac disorders,
moderate to severe respiratory insufficiency, alcoholism and raised
intracranial pressure or if hypersensitive to any ingredient.
Special warnings and precautions for use
Use with caution in hypokalaemia.
Interaction with other medicinal products and other forms of interaction
Cardiac glycosides may be present in squill. Serum levels of cardiac
glycosides (e.g. digoxin) may be increased by the concurrent
administration of certain antibiotics (such as erythromycin and
tetracycline) captopril, quinidine, and other drugs acting on the heart.
Fertility, pregnancy and lactation
As with other medicines, the product should not be taken during
pregnancy or lactation unless the benefits are considered to outweigh the
Effects on ability to drive and use machines
No significant effects have been reported.
Large doses may cause nausea, vomiting and diarrhoea.
Overdosage is unlikely in view of the emetic action of ipecacuanha.
However, if it does occur, cardiotoxicity may result from the absorption
of emetine or the cardiac glycosides in squill. Vasomotor collapse
followed by death could occur.
Ipecacuanha and squill have been used traditionally as expectorants.
Their reflex expectorant action is thought to occur as a result of an
irritant action on the respiratory tract producing cough.
No detailed information is available for ipecacuanha. The principal
alkaloid, emetine, is rapidly absorbed after oral administration and is
concentrated in liver, kidneys, lungs and spleen. It is excreted very
slowly with up to 35% being retained at 35 days. Its metabolic fate is
No Pharmacokinetic data are available for squill.
Preclinical safety data
No relevant data.
List of excipients
Compound orange spirit
Citric acid monohydrate
Powdered blackcurrant flavour
No major incompatibilities have been reported.
6 months once opened
Special precautions for storage
Store below 25°C.
Nature and contents of container
2000 ml white polythene bottle with white plastic screw cap with an
500 ml white polythene bottle with white plastic wadless screw cap.
Patient packs or OTC packs as appropriate
100 ml and 200 ml amber glass bottles with plastic Jay cap closures.
Special precautions for disposal
MARKETING AUTHORISATION HOLDER
Wise Pharmaceuticals Ltd
Hani Wells Business Park,
Unit 7, Hardicker Street,
MARKETING AUTHORISATION NUMBER(S)
DATE OF FIRST AUTHORISATION/RENEWAL OF THE
DATE OF REVISION OF THE TEXT
Source: Medicines and Healthcare Products Regulatory Agency
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