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CAPRIN 75MG GASTRO-RESISTANT TABLETS
CP Pharmaceuticals Limited
340 x 128
128 x 27 / 25
PHARMACODE TO VIEW
Shrinkwrapped in trays
PATIENT INFORMATION LEAFLET FOR ASPIRIN 75MG
1. What Aspirin 75mg Gastro-resistant Tablets are and what they are used for
Your medicine is called Aspirin 75mg Gastro-resistant Tablets (called Aspirin Tablets throughout the
rest of this leaﬂet).
What this medicine does
What this medicine does
Aspirin Tablets are used to reduce the likelihood of further heart
attacks or strokes in patients with a previous history patients
Aspirin Tablets are used to reduce the likelihood of further heart attacks or strokes in of these with a
conditions, when taken regularly. can also also be follow fol bypass
previous history of these conditions, when taken regularly. They They canbe taken takeninglowing
bypass surgery. product is slow release of Aspirin, this product is
surgery. Due to the slow release of Aspirin, thisDue to thenot useful for relieving acute pain.
not useful for relieving acute pain.
Aspirin belongs to a group of medicines called non-steroidal anti-inﬂammatory drugs (NSAIDs).
Aspirin belongs to a group of medicines called non-steroidal antiAspirin thins the blood which helps to reduce the likelihood of having a heart attack.
inﬂammatory drugs (NSAIDs). Aspirin thins the blood which helps to reduce the likelihood of
These tablets have been specially coated (enteric coating) to help minimise stomach upset and
having a heart attack.
feeling sick (sometimes experienced as side effects of these tablets – see Section 4 Possible side
These tablets have been specially coated (enteric coating) to help minimise stomach upset
and feeling sick (sometimes experienced as side effects of these tablets – see Section 4
Possible side effects).
2. Before you take Aspirin Tablets
There is a possible association between aspirin and Reye’s Syndrome when given to
children. Reye’s syndrome is a very rare disease, which can be fatal. For this reason aspirin
should not be given to children aged under 16 years, unless on the advice of a doctor.
Do not take Aspirin Tablets if you:
• are allergic (hypersensitive) to aspirin or other non-steroidal anti-inﬂammatory drugs (NSAIDs)
e.g. ibuprofen, or any of the other ingredients of Aspirin Tablets (see Section 6 What Aspirin Tablets contain).
Symptoms may include rhinitis (runny nose), swollen face, mouth or tongue, itchy rash or asthma attack
• have or have had a stomach ulcer;
• have a condition where your blood does not clot properly (e.g. haemophilia);
• are taking medicines to thin your blood such as warfarin;
• have or have had gout;
• are in the last 3 months of pregnancy or are breast-feeding.
Talk to your doctor or pharmacist if any of the following apply to you:
• if you have asthma, or suffer from allergies;
• if you have problems with your heart, kidneys or liver;
• if you are dehydrated;
• if you have nasal polyps (inflamed swellings inside the nose)
• if you suffer from indigestion (dyspepsia)
• if you have an infection
• if you have high blood pressure;
• if you have a lack of glucose 6-phosphate dehydrogenase (G6PD);
• if you are elderly.
• if you are diabetic.
The product belongs to a group of medicines which may impair the fertility in women. This effect is
reversible on stopping the medicine.
You should let your doctor know you are taking aspirin tablets, particularly if you are going to have
an operation, as you may need to stop taking your tablets several days before the operation.
Your blood, kidney and liver should be monitored during prolonged use of aspirin as blood,
kidney and liver disorders may develop.
Using other medicines
Before using aspirin you should inform a healthcare professional about the medicines you are taking.
If you are using aspirin regularly you should seek advice before taking any other medicine (including
other medicines you may have bought).
Make sure your doctor knows if you are taking a medicine listed here:
• Alcohol: some of the effects of aspirin are enhanced.
• Mifepristone (used to terminate pregnancy). You should not take aspirin until eight to twelve days
after mifepristone. If taken with aspirin this medicine may not be as effective.
• Non-steroidal anti-inﬂammatory (NSAIDs) e.g. ibuprofen or diclofenac sodium (used for pain
relief and to treat inﬂammation) or Corticosteroids e.g. prednisolone and betamethasone (used
to treat allergy or inﬂammation): if taken with aspirin you may have more severe side effects e.g.
increased risk of bleeding or ulcers in the stomach. If you suddenly stop taking corticosteroids you
may develop aspirin poisoning.
• Metoclopramide (used to treat nausea and vomiting): it may increase the effect of aspirin.
• Adsorbents e.g. kaolin (for diarrhoea) and Antacids e.g. aluminium hydroxide and magnesium
carbonate (used to treat indigestion): these medicines may reduce the effect of aspirin.
• Medicines known to affect the clotting of your blood: if you take one of these medicines below
with aspirin you may increase the likelihood of bleeding.
• Coumarins e.g. warfarin, phenindone, streptokinase or heparins (blood thinning medicines).
• Clopidogrel and ticlopidine (used to prevent strokes and heart attacks).
• Calcium channel blockers such as verapamil, used to treat high blood pressure.
• ACE Inhibitors or Angiotensin-II Receptor Antagonists e.g. captopril, enalapril, maleate,
valsartan, losartin (used to lower high blood pressure) taken with asprin these
medicines may not be as effective and you may suffer from Kidney problems.
• Antidepressants (used to treat depression) e.g. Selective Serotonin Re-uptake Inhibitors (SSRIs)
(such as venlafaxine): if taken with aspirin you may increase the likelihood of bleeding.
• Medicines to control epilepsy e.g. phenytoin and valproate: aspirin may increase the effect of
these medicines. If you take sodium valproate with aspirin you may increase the likelihood of bleeding.
• Zaﬁrlukast (used to prevent or treat asthma).
• Spironolactone (diuretic) water tablets, Probenicid or Sulﬁnpyrazone (used to treat gout) and
diuretics used to treat high blood pressure: if taken with aspirin these medicines may not be as
effective. Phenylbutazone may reduce the effect of aspirin.
• Methotrexate (used in the treatment of rheumatoid arthritis, Crohn’s disease and cancer) or
Carbonic anhydrase inhibitors e.g. acetazolamide (used in the treatment of glaucoma, epilepsy
and excess water retention): if taken with aspirin the side effects of these medicines may become
• Thiopental (used as an anaesthetic).
• Gold compounds (used to treat rheumatoid arthritis).
• Insulin and other drugs used to treat diabetes.
• Sulphonamides, such as sulphamethoxazole, used to treat infections.
• Vitamin C.
• Cilostazol (for leg pain that occurs when walking due to poor circulation): the dose of aspirin should
be no greater than 80mg a day.
Aspirin may affect the results of thyroid function tests.
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including
medicines obtained without a prescription.
Pregnancy and breast-feeding
If you are pregnant, thinking of becoming pregnant, or breast-feeding, ask your doctor or pharmacist for
advice before taking Aspirin Tablets.
3. How to take Asprin Tablets
For oral use.
Consult a doctor before commencing therapy for the ﬁrst time.
Follow the instructions on the label about how to take your medicine.
Check with your doctor or pharmacist if you are not sure.
Adults (including the elderly and children over 16 years)
The usual dose for long-term use is one or two tablets once daily.
The tablets should be swallowed whole with water. Do not chew,
crush or break the tablets. In some circumstances your doctor may advise a higher dose of up to
four tablets daily.
Take the tablets with or immediately after food to reduce the risk of getting stomach and bowel irritation.
Do not exceed the stated dose.
If symptoms persist for more than three days, consult your doctor.
Children and Adolescents
Aspirin should not be given to children aged under 16 years of age unless on the advice of a doctor.
If you take more Aspirin Tablets than you should
If you take more Aspirin Tablets than your doctor has prescribed contact your nearest hospital
casualty department or doctor immediately. Take the medicine or this leaﬂet with you to show
Symptoms of an overdose include vomiting, dehydration, tinnitus, vertigo, headache, nausea,
dizziness, restlessness, heart failure, breathing failure, deafness, sweating, warm extremities with
racing pulse, increased breathing rate and hyperventilation.
If you forget to take Aspirin Tablets
• If you forget to take a dose, do not worry. Take the next dose when it is due.
• Do not take double the amount to make up for a forgotten dose.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Aspirin Tablets can cause side effects, although not everybody gets them.
If you experience the following side effects while taking your medicine, you should stop
taking your tablets and tell your doctor straight away:
• allergic reaction (hypersensitivity) which may include lumpy skin or hives, skin rash, swelling of
eyelids, face, lips, mouth or tongue, or sudden wheeziness, or induce or worsen asthma attacks;
• you suffer from severe or persistent indigestion, stomach upset or pain, you may develop ulcers
or bleeding from the stomach which can cause severe stomach pain, bloody or black tarry stools or
Other possible side effects:
• stomach upset and feeling sick;
• an increased tendency to bleed;
• anaemia and other blood disorders;
• mouth ulcers;
• you may succumb to infections more easily;
• you may bruise more easily.
• slight blood loss may result in iron-deficiency anaemia during long term use;
• blood in the urine;
• Stevens-Johnson syndrome (fever, rash, sore mouth and eyes, joint and muscle aches);
• severe skin problem with shedding of upper layer;
Some patients have developed liver problems (particularly with high doses).
If any of the side effects get serious, or if you notice any side effects not listed in this leaﬂet, please
tell your doctor or pharmacist.
5. How to store Aspirin Tablets
Keep out of the reach and sight of children.
Do not use after the expiry date stated on the label. Do not store above 25°C. Store in the original
container in order to protect from moisture.
Do not use if you notice that the pack is damaged. Return it to your pharmacist.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how
to dispose of medicines no longer required. These measures will help to protect the environment.
6. Further information
What Aspirin Tablets contain
The active substance is aspirin. Each gastro-resistant tablet contains 75mg of aspirin.
The other ingredients are potato starch, calcium hydrogen phosphate, microcrystaIline cellulose,
talc, methacrylic acid copolymer (also contains sodium lauryl sulphate and polysorbate), macrogol
What Aspirin Tablets look like and contents of the pack
Aspirin Gastro-resistant Tablets are white, circular tablets, which are plain on both sides. Each pack
of Aspirin Gastro-resistant Tablets contains 28, 32, 56 or 84 tablets. Packs of 32, 56 or 84 tablets are
only available from your pharmacist. Not all pack sizes are marketed.
Marketing Authorisation Holder
Wockhardt UK Ltd, Ash Road North, Wrexham, LL13 9UF, UK
CP Pharmaceuticals Ltd, Ash Road North, Wrexham, LL13 9UF, UK
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Asprin 75mg GastroResistant Tablets
This leaﬂet was last revised in November 2010
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.