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Active substance(s): CALCIUM CARBONATE

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Calcichew® 500mg Chewable Tablets/Calcium Carbonate 500mg Chewable Tablets
(calcium carbonate)
Your medicine is known by one of the above names, but will be referred to
as Calcichew 500 mg throughout this:
Patient Information Leaflet
Read all of this leaflet carefully before you start taking this medicine
because it contains important information for you.

Always take this medicine exactly as described in this leaflet or as
your doctor or pharmacist have told you.

Keep this leaflet. You may need to read it again.

Ask your pharmacist if you need more information or advice.

You must talk to a doctor if you do not feel better or if you feel worse
after two weeks.

If you get any side effects talk to your doctor or pharmacist. This
includes any possible side effects not listed in this leaflet. See
section 4.
In this leaflet:
1) What Calcichew 500mg is and what it is used for
2) What you need to know before you take Calcichew 500mg
3) How to take Calcichew 500mg
4) Possible side-effects
5) How to store Calcichew 500mg
6) Contents of the pack and other information

1) What Calcichew 500mg is and what is it used for
Calcichew 500mg Chewable Tablets are orange flavoured chewable
tablets containing the active ingredient calcium. Calcium is found in the
diet and is an important substance in bone formation.
Calcichew 500mg is used to treat and prevent calcium deficiency which
may occur if your diet or lifestyle does not provide enough, or when body
requirements are increased. This medicine may also be prescribed or
recommended for certain bone conditions, for example osteoporosis, or
during pregnancy. It may also be given to patients receiving kidney dialysis
to remove the phosphate from the blood that cannot be removed by

2) What you need to know before you take Calcichew 500mg
Do not take Calcichew 500mg Chewable Tablets if you:
• are allergic (hypersensitive) to calcium or any of the other ingredients
of this medicine (listed in section 6)
• have a condition that causes excessive amounts of calcium in your
blood or urine (hypercalcaemia or hypercalciuria)
• have kidney stones.
Warnings and precautions
Talk to your doctor or pharmacist before taking Calcichew 500mg:
• if you have osteoporosis (brittle bones) and are also unable to move
• if you are on long term treatment, especially if you are taking
medicines for a heart disorder (cardiac glycosides), or diuretics
(used in the treatment of high blood pressure or oedema)
• if you have signs of impaired kidney function or a high tendency to
kidney stone (calculus) formation
• if you have cancer or any other conditions that may have affected your
Your serum calcium or phosphate levels, or urinary calcium excretion
must be monitored if you have any of the following conditions:
• kidney problems
• you are on long-term treatment with Calcichew
• you are already taking additional doses of calcium
If you have increased calcium levels in the blood or develop signs of
kidney problems, the dose of Calcichew 500mg should be reduced or the
treatment discontinued.
Other medicines and Calcichew 500mg
Tell your doctor or pharmacist if you are taking, have recently taken or
might take any other medicines.
In particular, the following medicines may interact with Calcichew 500mg

thiazide diuretics (water tablets); your serum calcium levels should
be monitored regularly.

cardiac glycosides (heart medicines); you should be monitored by
electrocardiogram (ECG) and your serum calcium levels measured.

tetracycline antibiotics; these should be taken at least two hours
before, or four to six hours afterwards. Calcium carbonate may
interfere with the absorption of tetracycline preparations if taken at the
same time.

levothyroxine (hormone used to treat thyroid deficiency); these
should be taken at least four hours before, or after taking Calcichew

Quinolone antibiotics (ciprofloxacin, lomefloxacin, norfloxacin,
sparfloxacin); the effect of these medicines may be reduced if taken
at the same time as calcium. Take quinolone antibiotics two hours
before or six hours after taking Calcichew 500mg.

Bisphosphonates should be taken at least one hour before
Calcichew 500mg.

Calcium salts may decrease the absorption of iron, zinc and
strontium ranelate. Consequently iron, zinc or strontium ranelate
preparations should be taken at least two hours before or after
Calcichew 500mg.
If you are taking any of the above-mentioned medicines, your doctor will
give you further instructions.
Taking Calcichew 500mg with food and drink
For treatment of calcium deficiency or use as an additional osteoporosis
therapy, Calcichew 500mg can be taken with or without food and drink.
For use as a phosphate binder, Calcichew 500mg should be taken just
before, during or just after each meal.
Pregnancy, breastfeeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are
planning to have a baby, ask your doctor or pharmacist for advice before
taking Calcichew 500mg.
During pregnancy the daily intake should not exceed 2500 mg calcium
(including food and supplementation). If you are pregnant, you may use
Calcichew 500mg in case of a calcium deficiency.
Calcichew 500mg can be used during breastfeeding. Calcium passes into
breast milk.
Driving and using machines
Calcichew 500mg has no known influence on the ability to drive or use
Calcichew 500mg contains isomalt
Calcichew 500mg contains isomalt (E953): if you have been told by your
doctor that you have an intolerance to some sugars, talk to your doctor
before taking this medicine. May be harmful to teeth.
Calcichew 500mg contains aspartame (E951), a source of phenylalanine
which may be harmful for people with phenylketonuria (a deficiency in the
enzyme which breaks down phenylalanine).

3) How to take Calcichew 500mg
Always take this medicine exactly as your doctor or pharmacist has told
you. Check with your doctor or pharmacist if you are not sure.
The recommended dose is:
For use as an additional osteoporosis therapy: One tablet 2 or 3 times
a day.
For calcium deficiency:
One tablet 2 or 3 times a day.
As a phosphate binder (for kidney failure patients on dialysis):
Your doctor will decide how many Calcichew 500mg Chewable Tablets
you need. The label the pharmacist puts on your medicine will tell you
exactly how many tablets to take.
Use in children
The recommended dose for children is one tablet 2 or 3 times a day.
The tablets can be chewed or sucked.
If you take more than you should
If you have taken more Calcichew 500mg than you should, talk to your
doctor or pharmacist immediately.

If you accidentally take more Calcichew 500mg than you should, you may
have an increase in your blood calcium levels. Symptoms of this are:
excessive thirst, nausea, vomiting, constipation, abdominal pain, muscle
weakness, tiredness, mental disturbances, lack of appetite, bone pain,
having to pass more water than usual, kidney problems and, in severe
cases, irregular heartbeat.

What Calcichew 500 mg looks like and contents of the pack
The tablets are round, white, uncoated convex and orange flavoured; they
may have small specks.
The tablets are packed in white, plastic bottles of 90 tablets.
PL 10383/1965

Very rarely in addition: irritability, continuing headache, lightheadedness,
muscle spasms, twitches and tingling sensation.

Calcichew 500 mg Chewable Tablets/
Calcium Carbonate 500 mg Chewable Tablets


If you forget to take Calcichew 500mg Chewable Tablets
Do not take a double dose to make up for a forgotten tablet.
If you have any further questions on the use of this medicine, ask your
doctor or pharmacist.

Who makes and repackages your medicine?
Your medicine is manufactured by Takeda Nycomed AS Drammensveien
852, P.O.Box 205 1372 Asker, Norway. Procured from within the EU and
repackaged by Product Licence Holder: Primecrown Ltd, 4/5 Northolt
Trading Estate, Belvue Road, Northolt, Middlesex, UB5 5QS.

4) Possible side effects

Leaflet date: 06.04.2017

Like all medicines, this medicine can cause side effects, although not
everybody gets them.

Calcichew is a registered trademark of Takeda AS, Norway.

Stop taking your medicine and see a doctor immediately if you
experience any of the following side effects. These side effects may be a
sign of milk-alkali syndrome (also called Burnett’s Syndrome) that is
reported to occur very rarely (affects less than 1 in 10,000 people):

Frequent urge to urinate


Loss of appetite, nausea or vomiting

Unusual tiredness or weakness, along with elevated levels of calcium
in the blood and kidney impairment.
Side effects may include:
Uncommon side effects (may affect up to 1 in 100 people):

excessive amounts of calcium in your blood (hypercalcaemia) or
in your urine (hypercalcuria) may occur with large doses
Rare side effects (may affect up to 1 in 1,000 people):



stomach ache

wind (flatulence)


heartburn (dyspepsia)
Very rare side effects (may affect less than 1 in 10,000 people):



If you are taking Calcichew 500mg Chewable Tablets because you are
having kidney dialysis, tell your doctor if you notice any white deposits on
your skin.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This
includes any possible side effects not listed in this leaflet. You can also
report side effects directly via the Yellow Card Scheme at: By reporting side effects you can help
provide more information on the safety of this medicine.

5) How to store Calcichew 500 mg
• Keep all medicines out of the sight and reach of children.
• Do not store above 30°C. Keep container tightly closed.
Protect from moisture.
• Do not use Calcichew 500 mg after the expiry date which is stated on the
label after EXP. The expiry date refers to the last day of that month. If
the tablets have changed shape or colour do not use.
• If the tablets become discoloured or show signs of any deterioration, you
should ask your pharmacist who will advise you what to do.
• Medicines should not be disposed of via wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer required.
These measures will help to protect the environment.

6) Contents of the pack and other information
What Calcichew 500 mg contains:
Each chewable tablet contains 1250mg calcium carbonate equivalent to
500 mg calcium.
The tablet also contains; sorbitol (E420), povidone, isomalt (E953), mono
and di-fatty acid glycerides, magnesium stearate, orange flavour, and
aspartame (E951).
This product is gluten and lactose free.

Additional Information
Calcichew 500mg contains calcium designed to keep bones healthy.
Calcium is an essential component of bones.
Requirements for calcium increase with age and, although many people
obtain enough calcium from their diet, some people may require a
supplement in order that their body has all the calcium it needs to maintain
healthy bones.
People with diets and lifestyles that mean they will obtain less than the
recommended intake of calcium are at risk of weakened bones. Prolonged
lack of adequate calcium intake can lead to the development of
osteoporosis, a condition where bones become weak to a level that
minimal trauma (for example, a fall) can result in a fracture, most typically
at the hip, spine or wrist.
Calcichew 500mg have been designed to give people, whose intake of
calcium is low, a boost to the recommended amounts.
Maintaining healthy bones and helping to avoid osteoporosis is an
important issue for many people. There are many ways that people can
help themselves: regular exercise, a balanced diet with an adequate intake
of calcium and, for some people, advice on how to prevent falls which may
lead to fracture.
The National Osteoporosis Society (NOS) in the UK and the Irish
Osteoporosis Society (IOS) in the Republic of Ireland, are national
charities dedicated to improving the diagnosis, prevention and treatment of
osteoporosis. The NOS and IOS offer support to people with osteoporosis
and raise awareness of the importance of healthy bones.
For patients in the UK, if you are concerned about osteoporosis, please
contact the National Osteoporosis Society, Camerton, Bath BA2 0PJ. Tel:
01761 471 771, Fax: 01761 471 104 or email: For
patients in the Republic of Ireland, please contact the Irish Osteoporosis
Society, 114 Pembroke Road, Garden Level, Ballsbridge, Dublin 4. Tel:
1890 252 751, Fax: +353 (0)1 668 0098, email:

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