Skip to Content

UK Edition. Click here for US version.


Active substance(s): CALCIUM CARBONATE

View full screen / Print PDF » Download PDF ⇩
Calcichew® 500mg Tablets/ Calcioral® 500mg Tablets
(calcium carbonate) equivalent to 500mg Calcium
Your medicine is available using one of the above names but will be referred
to as Calcichew 500mg throughout the following:
Patient Information Leaflet
Read all of this leaflet carefully because it contains important
information for you.
This medicine is available without prescription. However, you still need to
take Calcichew 500mg Chewable Tablets carefully to get the best results
from it.
• Keep this leaflet. You may need to read it again.
• Ask your pharmacist if you need more information or advice
• You must contact a doctor if your symptoms worsen or do not improve
after two weeks.
• If any of these side-effects become serious, or if you notice any side
effect(s) not listed in this leaflet, please talk to your doctor or
In this leaflet:
1) What Calcichew 500mg Tablets are and what they are used for
2) Before you take Calcichew 500mg
3) How to take Calcichew 500mg
4) Possible side effects
5) How to store Calcichew 500mg
6) Further information

1) What Calcichew 500mg Tablets are and what they are used
Calcichew 500mg are orange flavoured chewable tablets. They contain the
active ingredients:
• Calcium (1250mg calcium carbonate: equivalent to 500mg calcium)
Calcium is found in the diet.
Calcichew 500mg may be prescribed by doctors or recommended by
pharmacists to treat and prevent calcium deficiency, or when the diet or
lifestyle does not provide enough, or when body requirements are increased.
This medicine may also be prescribed or recommended for certain bone
conditions, for example osteoporosis, or in pregnancy. It may also be given to
patients receiving kidney dialysis to remove the phosphate from food that
cannot be removed by dialysis.

2) Before you take Calcichew 500mg
Do not take Calcichew 500mg Tablets if you:
• are allergic (hypersensitive) to any of the ingredients (see end of Section
2 and Section 6)
• have a condition causing high levels of calcium in your blood or urine
(hypercalcaemia or hypercalciuria) e.g.
o severe kidney failure in people not on dialysis – you should not take
this medicine unless advised by your doctor
o cancer which has affected your bones
• have kidney stones.
Take special care with Calcichew 500mg
If any of the following applies to you, please tell your doctor:
• phenylketonuria (a deficiency in the enzyme which breaks down
phenylalanine) as these tablets contain aspartame, a source of
• brittle bones (osteoporosis) as a result of being immobile
• taking medicines for your heart, or diuretics
• a high tendency to kidney stone (calculus) formation
• cancer or any other conditions that may have affected your bones.
Your serum calcium or phosphate levels, or urinary calcium excretion
must be monitored if you have any of the following conditions.
• kidney problems
• you are on long-term treatment with Calcichew
• you are already taking additional doses of calcium
If you have increased calcium levels in the blood or develop signs of kidney
problems, the dose of Calcichew 500mg should be reduced or the treatment

Taking other medicines
Please inform your doctor or pharmacist if you are taking or have recently
taken any other medicines, including medicines obtained without a
In particular, the following medicines may interact with Calcichew 500mg
• diuretics (water tablets); your serum calcium levels should be monitored
• heart medicines (cardiac glycosides); you should be monitored by
electrocardiogram and your serum calcium levels measured.
• corticosteroids (e.g. prednisolone, dexamethasone); your dose of
Calcichew 500mg may need to be increased
• tetracycline antibiotics; these should be taken at least two hours before,
or four to six hours afterwards.
• hormones (levothyroxine); these should be taken at least four hours
before, or afterwards.
• anti-infectives (Quinolones: Ciprofloxacin, lomefloxacin, norfloxacin,
sparfloxacin): please speak with your doctor.
• fluoride, or bisphosphonates; Calcichew 500mg should be taken at
least three hours afterwards.
Taking Calcichew 500mg with food and drink
Calcichew 500mg should not be taken within 2 hours of eating foods rich in
oxalic acid (found in spinach and rhubarb) or phytic acid (found in whole
Pregnancy and breastfeeding
Ask your doctor or pharmacist for advice if you are pregnant or breast-feeding
before taking Calcichew 500mg.
Driving and using machines
Calcichew 500mg has no known effect on your ability to drive or use
Important information about some of the ingredients of Calcichew
The following are ingredients in this product:
• Sorbitol and isomalt: if you have been told by your doctor that you have
an intolerance to some sugars, talk to your doctor before taking this
• Aspartame contains a source of phenylalanine and may be harmful to
people with phenylketonuria (a deficiency in the enzyme which breaks
down phenylalanine).

3) How to take Calcichew 500mg
Always take Calcichew 500mg exactly as your doctor has told you. You
should check with your doctor or pharmacist if you are not sure.
For use as additional osteoporosis therapy:
Adults and the elderly:
Chew or suck one tablet 2 or
3 times a day.
For calcium deficiency:
Adults, the elderly and children:
Chew or suck one tablet 2 or
3 times a day.
For osteomalacia (a softening of the bone):
Adults and the elderly:
Chew or suck two to six
chewable tablets a day.
When Calcichew 500mg Chewable Tablets are given to patients on kidney
dialysis, the dose will be different for each patient. Your doctor will decide how
many Calcichew 500mg Chewable Tablets you need.
The tablets should be taken just before, during or just after each meal to
make sure that the calcium binds to the phosphate in the stomach.
If you take more than you should
If you accidentally take more Calcichew 500mg than you should, you may
have an increase in your blood calcium levels.
Symptoms of this are: excessive thirst, nausea, vomiting, constipation,
abdominal pain, muscle weakness, tiredness, mental disturbances, lack of
appetite, bone pain, having to pass more water than usual, kidney problems
and, in severe cases, irregular heartbeat.
Very rarely in addition: irritability, continuing headache, lightheadedness,
muscle spasms, twitches and tingling sensation.

Do not take any more Calcichew 500mg and contact your doctor or
emergency department as soon as possible. Take the packet and any
remaining tablets with you.

Street, 63308 Polva, Estonia. Procured from within the EU and repackaged by
the Product Licence holder: Primecrown Ltd, 4/5 Northolt Trading Estate,
Belvue Road, Northolt, Middlesex, UB5 5QS.

If you forget to take Calcichew 500mg
If you forget to take a dose, leave out that dose completely. Take your next
dose when it is due. Do not take a double dose to make up for a forgotten

Leaflet date: 31.03.2015

4) Possible side effects

Calcichew 500mg contains calcium designed to keep bones healthy. Calcium
is an essential component of bones.

Like all medicines, Calcichew 500mg can cause side-effects, although not
everybody gets them.
Side effects with Calcichew 500mg may include:
Uncommon side-effects (affecting less than 1 in 100 people):
• too much calcium in your blood (hypercalcaemia) – the symptoms
include nausea, vomiting, lack of appetite, constipation, stomach ache,
bone pain, extreme thirst, a need to pass more water than usual, muscle
weakness, drowsiness and confusion.
• too much calcium in your urine (hypercalciuria)
Rare side-effects (affecting less than 1 in 1000 people):
• nausea
• stomach ache
• constipation
• diarrhoea
• wind (flatulence)
• rash
• hives
• itching
Very rare side-effects (affecting less than 1 in 10000 people):
ƒ Milk alkali syndrome –(usually only seen in overdose see “if you take
more than you should”)
If you are taking Calcichew 500mg Chewable Tablets because you are having
kidney dialysis, tell your doctor if you notice any white deposits on your skin.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This
includes any possible side effects not listed in this leaflet. You can also report
side effects directly via the Yellow Card Scheme at: By reporting side effects, you can help provide
more information on the safety of this medicine.

5) How to store Calcichew 500mg
• Keep out of the sight and reach of children.
• Do not store above 25°C. Keep the container tightly closed to protect from
• Don’t use after the expiry date which is stated on the carton or container
label. The expiry date refers to the last day of that month.
• If the tablets become discoloured or show any other signs of deterioration,
you should seek the advice of your pharmacist who will tell you what to do
• Medicines should not be disposed of via wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer required. These
measures will help to protect the environment.

6) Further Information
What Calcichew 500mg Tablets contain
Each tablet contains 1250mg calcium carbonate (equivalent to 500mg
The other ingredients are: sorbitol (E420), povidone, isomalt (E953), mono,
di-fatty acid glycerides, magnesium stearate, orange flavour, and aspartame
(E951) (see also end of Section 2 “Important information about some of the
ingredients of Calcichew 500mg”).
What Calcichew 500mg look like and contents of the pack
The tablets are unmarked, round, white and chewable.
Calcichew 500mg Tablets are available in bottles of 60 tablets.
PL 10383/1236


Who makes and repackages your medicine?
Your medicine is manufactured by Takeda Nycomed AS, Drammensveien
852, P.O. Box 205, 1372 Asker, Norway or Takeda Pharma AS, 55B Jaama

Calcichew is a registered trademark of Takeda Nycomed AS, Norway.
Additional information

Requirements for calcium increase with age and, although many people
obtain enough calcium from their diet, some people may require a supplement
in order that their body has all the calcium it needs to maintain healthy bones.
People with diets and lifestyles that mean they will obtain less than the
recommended intake of calcium are at risk of weakened bones. Prolonged
lack of adequate calcium intake can lead to the development of osteoporosis,
a condition where bones become weak to a level that minimal trauma (for
example, a fall) can result in a fracture, most typically at the hip, spine or
Calcichew 500mg have been designed to give people, whose intake of
calcium is low, a boost to the recommended amounts.
Maintaining healthy bones and helping to avoid osteoporosis is an important
issue for many people. There are many ways that people can help
themselves: regular exercise, a balanced diet with an adequate intake of
calcium and, for some people, advice on how to prevent falls which may lead
to fracture.
For patients in the UK, the National Osteoporosis Society (NOS) is a national
charity dedicated to improving the diagnosis, prevention and treatment of
osteoporosis. The NOS offers support to people with osteoporosis and raises
awareness of the importance of healthy bones.
If you are concerned about osteoporosis, please contact the National
Osteoporosis Society, Camerton, Bath BA2 0PJ. Tel: 01761 471 771, Fax:
01761 471 104 or email:

Expand view ⇕

Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.