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NAME OF THE MEDICINAL PRODUCT
QUALITATIVE AND QUANTITATIVE COMPOSITION
Anunonium Bicarbonate BP
Ipecacuanha Tincture BP
Squill Liquid Extract BP
Dark Brown Oral Solution.
A traditional remedy for the temporary relief of symptoms of catarrh and
Posology and method of administration
‘Bronchial’ Mixture is for oral administration.
Not recommended to children under 12 years
Adults (including the elderly):
Two 5ml spoonful diluted with an equal quantity of water, to be sipped slowly
three times a day.
Impaired renal function, impaired hepatic function, cardiac disorders,
moderate to severe respiratory insufficiency, alcoholism and raised intracranial
pressure or if hypersensitive to any ingredient.
Special warnings and precautions for use
The product labelling also contains the following warnings:
Do not exceed the stated dose.
Contact your doctor immediately if too much is taken.
If symptoms persist, consult your doctor.
Not to be taken by children under 12 years.
Store out of children’s reach.
Interaction with other medicinal products and other forms of interaction
An interaction between tricyclic antidepressants and ipecacuanha has been
Fertility, Pregnancy and lactation
There is inadequate evidence of the safety of the active ingredients in human
pregnancy, but they have been widely used for many years without significant
reports of problems.
Effects on ability to drive and use machines
Large doses of ‘Bronchial’ Mixture may cause nausea and vomiting. A case of
gastric rupture caused by an emetic dose of ipecacuanah has been reported.
No special procedures or antidotes are likely to be needed in healthy adults but
see ‘Contraindications’ (4.3).
Ammonium bicarbonate and squill are expectorants.
Ipecacuanha is an emetic and expectorant.
Preclinical safety data
List of excipients
Quantity per 5 ml dose
Benzoic acid BP
Senga liquid extract BP
Tolu solution (1980) BP
Capiscum tincture (1973) BPC
Anise Oil BP
Caramel BPC (1973)
Purified water, Ph.Eur.
TO 5.0 ml
36 Months from date of manufacture.
Special precautions for storage
Store below 25°C.
Nature and contents of container
The product containers are round amber bottles with screw caps, containing
100 ml or 200 ml of product. The Rusco bottles are contained in cartons.
Carton: White backed folding box board printed on white.
Special precautions for disposal
For oral administration after dilution with an equal quantity of water.
MARKETING AUTHORISATION HOLDER
Activase Pharmaceuticals Limited,
11 Boumpoulinas, 3rd Floor,
MARKETING AUTHORISATION NUMBER(S)
DATE OF FIRST AUTHORISATION/RENEWAL OF THE
31st January 1998
DATE OF REVISION OF THE TEXT
Source: Medicines and Healthcare Products Regulatory Agency
Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.