BOOTS VEGETABLE LAXATIVE TABLETS
Trade Name of the Medicinal Product
Boots Vegetable Laxative Tablets
Qualitative and Quantitative Composition
Compound colocynth extract
Hyoscyamus dry extract
Quantity/unit dose mg
White, sugar-coated tablet
For the relief of occasional constipation.
Posology and Method of Administration
For oral administration.
Adults and children over 12 years: Unless otherwise directed by the doctor, one to three
tablets to be taken with water.
Children under 12 years: Not suitable for children under 12 years.
Elderly: The normal adult dosage is appropriate in the elderly.
Hypersensitivity to any of the ingredients. Contraindicated in patients with abdominal pain,
nausea and vomiting, prostatic enlargement, pyloric stenosis, closed angle glaucoma,
paralytic ileus, toxic megacolon and myasthenia gravis.
Special Warnings and Precautions for Use
This product should not be used for prolonged periods since it may decrease the sensitivity
of the intestinal mucous membranes, so larger doses have to be taken and the bowel fails to
respond to normal stimuli.
Should be used with caution in patients with asthma, hypertension, cardiac dysfunction,
tachycardia and unstable angina.
Warning: Do not exceed the stated dose.
For use in occasional constipation.
Laxatives should not be taken where there is severe abdominal pain or used regularly for
prolonged periods except on medical advice.
Keep all medicines out of the reach of children.
Interactions with other Medicaments and other forms of Interaction
The effects of the hyoscyamus content may be enhanced by other drugs with anticholinergic
properties including amantadine, some antihistamines, butyrophenones, phenothiazines and
Pregnancy and Lactation
The use of this product during pregnancy and lactation is contraindicated.
Effects on Ability to Drive and Use Machines
No adverse effects known.
Undesirable effects may include dryness of the mouth, thirst, mydriasis, loss of
accommodation, dysphagia, impotence, urinary retention or hesitancy, dermal flushing,
dizziness, insomnia, photophobia, increased intraocular pressure, dry skin, bradycardia,
followed by tachycardia with palpitations and arrhythmias.
Prolonged use may produce watery diarrhoea with excessive loss of fluid and electrolytes,
muscular weakness and weight loss.
Symptoms of overdosage may include those given under 4.8 above and severe abdominal
pain, vomiting, diarrhoea with blood-stained watery stools and delirium, hyperpyrexia
(particularly in children), urinary retention and excitation.
Treatment consists of emptying the stomach by emesis or aspiration and lavage. Treatment
should include symptomatic and supportive measures, replacement of fluid and electrolyte
losses and the administration of neostigmine injection, either subcutaneously or
intramuscularly, to reverse the peripheral anticholinergic effects.
Jalap and colocynth are stimulant (drastic) purgatives. Hyoscyamus dry extract has
anticholinergic properties and counteracts the spasm and griping induced by jalap and
Peppermint oil has carminative properties and also counteracts the griping induced by jalap
Preclinical Safety Data
There are no preclinical data of relevance to the prescriber which are additional to that
List of Excipients
Maize starch pdr
Liquid glucose BPC '63 (solids)
French chalk for tablets (tablet dusting)
Titanium dioxide (powder 16)
French chalk for tablets
Light petroleum 125-150°
Heavy magnesium carbonate
Stearic acid pdr
Special Precautions for Storage
Nature and Contents of Container
30ml rectangular amber glass bottle having a wadless white polypropylene cap; the ullage is
filled with cotton wool.
Pack size: 100
Instructions for Use/Handling
Marketing Authorisation Holder
The Boots Company PLC
1 Thane Road West
Nottingham NG2 3AA
Marketing Authorisation Number
Date of First Authorisation/Renewal of Authorisation
Date of first authorisation: 24 March 1988
Date of last renewal: 24 March 1993
Date of (Partial) Revision of the Text