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Active substance(s): ST JOHNS WORT EXTRACT

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Patient Information Leaflet


2. Before you take this product

Higher Nature St John’s Wort
Mood Uplift

DO NOT TAKE this product if:
● you are under 18 years of age
● you are pregnant or breastfeeding
● you are allergic to any of the ingredients (listed in section 6)
● your skin is exceptionally sensitive to sunlight (photosensitive)
● you are having light treatment (phototherapy) for any condition
● you are suffering from depression (see below)

Coated tablets
St John’s Wort extract 425mg

All hormonal contraceptives

All medicines for depression/anxiety

Suffering from depression?
Symptoms of depression include feelings of helplessness and hopelessness, loss
of interest in daily activities, appetite or weight changes, sleep changes, loss of
energy and difficulty concentrating. If your doctor has told you that you are suffering
from depression do not use this product. If you think that you may be suffering from
depression you should tell your doctor.

Please read this leaflet carefully before you start taking these tablets.
It contains some important information about Higher Nature St John’s Wort Mood
Keep this leaflet with the tablets.
You may want to read it again or show it to your doctor, pharmacist or qualified
healthcare practitioner.

Tell your doctor before using this product if you have an intolerance to some
sugars (see section 6).

What is in this leaflet
1: What this product is and what it is used for . . . . . . . . . . . . . . . . .page 1
2: Before you take this product . . . . . . . . . . . . . . . . . . . . . . . . pages
3: How to take this product . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 4
4: Possible side-effects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 5
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 5
5: How to store this product

This product is a traditional herbal medicinal product containing St John’s Wort. Each
coated tablet of this product contains 425mg of extract (as dry extract) from St John’s
Wort aerial parts (Hypericum perforatum L.) (3.5-6:1) (equivalent to 1490-2550mg of St
John’s Wort). Extraction solvent: ethanol 60% v/v.

HRT tablets, patches, gels, vaginal rings.

All medicines for thinning the blood

Warfarin, acenocoumarol.

All medicines for epilepsy

Carbamazepine, phenobarbitone,
phenytoin, primidone, sodium valproate.

All immunosuppressant medicines

Ciclosporin, tacrolimus.

All medicines for HIV infections

Amprenavir, atazanavir, darunavir,
fosamprenavir, indinavir, lopinavir,
nelfinavir, ritonavir, saquinavir, tipranavir,
efavirenz, nevirapine, delavirdine.

Driving and operating machinery
In rare cases St John’s Wort may make you feel dizzy or sleepy. If affected do not drive
or use machines.

Some medicines for cholesterol

Simvastatin, atorvastatin.

Some medicines for cancer

Irinotecan, dasatinib, erlotinib, imatinib,
sorafenib, sunitinib, etoposide, mitotane.

Some medicines for heart disease

Digoxin, ivabradine, amiodarone.

Some medicines for migraines

Almotriptan, eletriptan, frovatriptan,
naratriptan, rizatriptan, sumatriptan,

Some medicines for high blood

Amlodipine, nifedipine, felodipine,

A medicine for regulating mood


A thyroid hormone


St John’s Wort can affect the way some medicines work and reduce their
effectiveness. Medicines that can be affected by St John’s Wort include prescription
medicines, and those that you may have bought yourself without a prescription.

1. What this product is and what it is used for

All hormonal replacement therapy
(HRT) treatments

While you are taking this product:
● avoid excessive sunbathing or the use of sunbeds/solariums
● stop using it at least 10 days prior to undergoing any surgery

this product with other medicines

6: Further information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . page 6

The birth control ‘Pill’, emergency
contraception (also known as 'the
morning after pill'), hormonal implants,
creams, patches, intra-uterine devices
with hormones.
Amitriptyline, clomipramine,
moclobemide, citalopram, escitalopram,
fluoxetine, fluvoxamine, paroxetine,
sertraline, duloxetine, venlafaxine.

Therefore it is important that you do not take St John’s Wort if you are using any of the
medicines listed in the table.

Higher Nature St John’s Wort Mood Uplift is a traditional herbal medicinal
product used for the relief of slightly low mood and mild anxiety based on
traditional use only.




St John’s Wort may also affect the following medicines. Therefore do not take this
product with these medicines unless a doctor or pharmacist has said it is safe to do so:
● fentanyl, propofol, sevoflurane, and midazolam (anaesthetics/pre-operative
● tramadol (an analgesic)
● erythromycin, clarithromycin and telithromycin (antibiotics)
● itraconazole and voriconazole (antifungals)
● artemether and lumefantrine (antimalarials)
● rasagiline (an anti-Parkinson’s medicine)
● aripiprazole (an antipsychotic medicine)
● buspirone (an anxiolytic)
● aprepitant (used to treat post-operative vomiting)
● butobarbital and phenobarbital (barbiturates)
● methyl phenidate (a central nervous system or CNS stimulant)
● exemestane (a hormone antagonist)
● eplerenone (a diuretic)
● lansoprazole and omeprazole (proton pump inhibitors)
● theophylline (a bronchodilator).
● gliclazide (an antidiabetic medicine)
3. How to take this product
Adults and the elderly.
Take 1 tablet daily.
Swallow the tablets whole with some water or other liquid. Do not chew the tablets.
Do not exceed the stated dose.

4. Possible side-effects

6. Further information

Like all medicines, this product can have side-effects, although the frequency is
not known. These side-effects are listed below.

Each coated tablet of this product contains 425mg of extract (as dry extract) from
St John’s Wort aerial parts (Hypericum perforatum L.) (3.5-6:1) (equivalent to 14902550mg of St John’s Wort). Extraction solvent: ethanol 60% v/v.

● digestive upsets such as indigestion,
loss of appetite, nausea, diarrhoea,
● fatigue and restlessness
● allergic skin reactions
such as rash, hives or itching

This product also contains the following ingredients:
Tablet core:
Maltodextrin, silica colloidal anhydrous, microcrystalline cellulose, croscarmellose
sodium, sodium starch glycolate (Type A), magnesium stearate.
Hypromellose, sucrose, talc, calcium carbonate E170, tragacanth, acacia, liquid
glucose (dry substance), titanium dioxide E171, iron oxide hydrate E172 (yellow iron
oxide), vanillin, beeswax white, carnauba wax, shellac.

Stop taking this product immediately if
you experience an allergic reaction.

Other side-effects
These include headaches, nerve pain or tingling (neuropathy), anxiety, dizziness
and mania. Also sunburn-like reactions in skin exposed to strong ultra-violet (UV)
irradiation (e.g. sun, solarium) have been reported, particularly in fair-skinned

If you have been told by your doctor that you have an intolerance to some
sugars, contact your doctor before taking this product.
Each coated tablet contains 6mg of glucose and 234mg of sucrose.

If you notice any other side-effects not mentioned above, tell your doctor
or pharmacist.

Each pack contains 30 coated tablets.

Other side-effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes
any possible side-effects not listed in this leaflet. You can also report side-effects
directly via the Yellow Card Scheme at: By reporting
side-effects you can help provide more information on the safety of this medicine.

Registration holder for this product
Schwabe Pharma (UK) Ltd
Alexander House, Mere Park,
Dedmere Road, Marlow, Bucks, SL7 1FX
Manufacturer of this product
Wiewelhove GmbH
Gildestrasse 39, 49477 Ibbenbüren, Germany

5. How to store this product

If you take too much of this product (overdose).
If you take more than the recommended dose, speak to a doctor, pharmacist or
qualified healthcare practitioner and take this leaflet with you.

Traditional Herbal Registration number:
THR 23056/0007

Do not use your tablets after the expiry date.
Return any out-of-date tablets to your pharmacist who will dispose of them for you.
The expiry date is printed on the box and the blister pack.

If you forget to take this product.
Continue to take your usual dose at the usual time, it does not matter if you have
missed a dose.

If you would like further information about this product, please contact:
Higher Nature
Burwash Common
East Sussex, TN19 7LX
Telephone: 0870 0664478

Store the product in a cool dry place.
Do not store the tablets in a place where the temperature goes above 25°c.

If you have any questions, or are unsure about anything, please ask your doctor,
pharmacist or qualified healthcare practitioner.

Keep your tablets out of the reach and sight of children.
Keep your tablets in the blister pack until it is time to take them.

Leaflet last revised 11/2015.






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Further information

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